Astaxanthin
Evidence: ★★★☆☆ · Status: OTC Supplement
In plain English
One of nature's strongest antioxidants (what makes salmon pink). Protects cell membranes, skin against UV, and mitochondria.
How it works
Carotenoid antioxidant (from algae) that spans cell membranes and quenches singlet oxygen far more potently than vitamin E; activates NRF2, supports mitochondria, skin, and eye health.
Molecular target & official sources
Astaxanthin (PubChem CID 5281224) · Examine: astaxanthin
Protocol
4–12 mg/day with fat.
Bottom line
Potent, safe antioxidant with skin and mitochondrial benefits.
Helps with: Endurance · Live Longer · Skin & Hair
The human evidence
A fat-soluble carotenoid antioxidant; the best human evidence is for skin (UV resilience, elasticity), with smaller studies suggesting modest endurance and eye-fatigue benefit. Very safe.
Stacks with
Take with a fatty meal or omega-3 for absorption.
Shares a pathway — often paired with: Omega-3 (EPA/DHA), Metformin, Statins (Atorvastatin/Rosuvastatin), Magnesium.
Availability & where to buy
Available over the counter. Widely available OTC — e.g. iHerb (ships worldwide); in Singapore also Guardian, Watsons, GNC, Shopee / Lazada. Look for a third-party-tested / GMP mark and check the dose per serving. Moderate — ~S$20–40/month for a quality algae-derived source.
How it works: the Mitochondria pathway →
Used in these protocols
Common questions
Does Astaxanthin actually work?
Human-evidence rating: 3 of 5. Potent, safe antioxidant with skin and mitochondrial benefits.
How do you take Astaxanthin?
4–12 mg/day with fat.
Is Astaxanthin legal or approved?
Regulatory status: OTC Supplement.