Statins (Atorvastatin/Rosuvastatin)

Evidence: ★★★★★ · Status: FDA Approved

In plain English

Turn down your liver's cholesterol factory so it pulls LDL out of your blood instead. The most evidence-backed drugs for preventing heart attacks. Pair with CoQ10 (statins deplete it).

How it works

Inhibit HMG-CoA reductase (HMGCR), the rate-limiting enzyme of cholesterol synthesis → upregulated LDL receptors clear LDL from blood; also anti-inflammatory (lower CRP).

Molecular target & official sources

HMGCR (NCBI Gene) · Atorvastatin (PubChem CID 60823)

Bottom line

Cornerstone of cardiovascular prevention.

Helps with: Cardiovascular

Stacks with

Shares a pathway — often paired with: Omega-3 (EPA/DHA), Metformin, Magnesium, SGLT2 Inhibitors (Empagliflozin / Canagliflozin).

Availability & where to buy

Available over the counter. Widely available OTC — e.g. iHerb (ships worldwide); in Singapore also Guardian, Watsons, GNC, Shopee / Lazada. Look for a third-party-tested / GMP mark and check the dose per serving.

How it works: the Mitochondria pathway →

Used in these protocols

• High Cholesterol / Lipids

Compare Statins (Atorvastatin/Rosuvastatin)

• Statins (Atorvastatin/Rosuvastatin) vs Omega-3 (EPA/DHA)
• Statins (Atorvastatin/Rosuvastatin) vs Semaglutide (Ozempic / Wegovy / Rybelsus)
• Statins (Atorvastatin/Rosuvastatin) vs Amphetamine (Adderall) / Lisdexamfetamine (Vyvanse)
• Statins (Atorvastatin/Rosuvastatin) vs PCSK9 Inhibitors (Evolocumab, Inclisiran)
• Statins (Atorvastatin/Rosuvastatin) vs Magnesium
• Statins (Atorvastatin/Rosuvastatin) vs L-Citrulline / Citrulline Malate
• Statins (Atorvastatin/Rosuvastatin) vs Ephedrine (EC/ECA stack)