GHSR
GHSR growth hormone secretagogue receptor — the molecular target that 3 compounds in the wiki act on.
In one line: The "hunger and growth-hormone" receptor that ghrelin — and several peptides — switch on.
GHSR is the receptor for ghrelin, your hunger hormone. When it's activated, two things happen: you feel hungry, and your pituitary gland releases a pulse of growth hormone. A family of peptides (ipamorelin, MK-677, and others) work by pressing this receptor to raise growth hormone naturally — using your own pituitary rather than injecting synthetic hormone.
The upside: more growth hormone means better recovery, deeper sleep, and fuller muscles. The trade-offs come from the same button: increased appetite and, with the stronger ones, water retention and higher blood sugar.
The appeal of these over injecting growth hormone directly is that they keep the body's natural, pulsing rhythm rather than flooding it constantly.