Ipamorelin
Evidence: ★★★☆☆ · Status: Not Approved
In plain English
Presses the "release growth hormone now" button cleanly — without making you ravenous or spiking stress hormones like the older versions did.
How it works
Selective GHSR (ghrelin receptor) agonist (pentapeptide) that triggers GH release without the cortisol, prolactin, or hunger spikes of older GHRPs.
Molecular target & official sources
GHSR growth hormone secretagogue receptor (NCBI Gene) · Ipamorelin (PubChem CID 9831659)
Bottom line
The "clean" ghrelin-side peptide; standard partner to CJC-1295.
Helps with: Hormones & Testosterone · Stress & Anxiety
Stacks with
Shares a pathway — often paired with: Magnesium, Phentermine / Qsymia (phentermine-topiramate), Ashwagandha (Withania somnifera), Vitamin C (Ascorbate).
Availability & where to buy
Not widely approved. Not approved for general sale in most markets (Singapore included). Grey-market only — dose, purity and legality uncertain.
How it works: the HPA axis pathway →
Common questions
Does Ipamorelin actually work?
Human-evidence rating: 3 of 5. The "clean" ghrelin-side peptide; standard partner to CJC-1295.
Is Ipamorelin legal or approved?
Regulatory status: Not Approved.