Epithalon (Epitalon)

Evidence: ★★☆☆☆ · Status: Not Approved

In plain English

Claims to switch on the enzyme that rebuilds the protective caps on your DNA (telomeres). Intriguing but the evidence is largely old, single-group, and hard to verify.

How it works

Tetrapeptide reported to activate telomerase (TERT), lengthening telomeres, and to normalise melatonin/circadian rhythm. Most data are older Russian studies.

Molecular target & official sources

TERT telomerase (NCBI Gene) · Epitalon (PubChem CID 219042)

Watch out

Telomerase activation is also a cancer concern; weak independent data.

Bottom line

Popular in longevity circles; evidence quality is the weak point.

Helps with: Sleep Better · Live Longer

Stacks with

Shares a pathway — often paired with: EPO (Erythropoietin), Tesamorelin (Egrifta), Human Growth Hormone (Somatropin), Insulin (anabolic misuse).

Availability & where to buy

Not widely approved. Not approved for general sale in most markets (Singapore included). Grey-market only — dose, purity and legality uncertain.

How it works: the PI3K/Akt growth factor pathway →