Human Growth Hormone (Somatropin)

Evidence: ★★★★☆ · Status: Prescription, Controlled

In plain English

The actual hormone, injected — rather than coaxing your pituitary to make more. Powerful for genuine deficiency; misused for physique it carries real metabolic and growth risks.

How it works

Recombinant GH acts directly on the GH receptor (GHR) → JAK2/STAT5 signalling → hepatic IGF-1, driving lipolysis, protein synthesis, and collagen turnover.

Molecular target & official sources

GHR growth hormone receptor (NCBI Gene) · Somatropin (PubChem)

Watch out

Insulin resistance, edema, carpal tunnel, acromegaly features, possible tumour growth. Controlled/prescription.

Bottom line

Legitimate for diagnosed deficiency; high-risk off-label.

Helps with: Build Muscle & Strength · Lose Fat · Hormones & Testosterone · Skin & Hair

Stacks with

Shares a pathway — often paired with: EPO (Erythropoietin), Tesamorelin (Egrifta), Insulin (anabolic misuse), Ligandrol (LGD-4033).

Availability & where to buy

Controlled substance. A controlled substance in most countries — illegal to buy, sell or possess without authorisation (in Singapore: HSA / CNB). Education only.

How it works: the PI3K/Akt growth factor pathway →

Compare Human Growth Hormone (Somatropin)

• Human Growth Hormone (Somatropin) vs Vitamin D3 (+ K2)
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• Human Growth Hormone (Somatropin) vs Tretinoin / Retinoids
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