Browse medicines, page 3 of 49
Some records contain detailed evidence; others currently contain only basic identity and regulatory information. Reviewed conclusions appear only when they are available for a specific use and group of people.
Showing 121–180 of 2,899 records
Levothyroxine (Synthroid / Euthyrox / Levoxyl / Unithroid / Tirosint)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
An underactive thyroid gland
Linezolid (Zyvox)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Serious infections caused by resistant Gram-positive bacteria, including MRSA and vancomycin-resistant enterococci
Mesalamine (Rowasa / Canasa / Asacol / Pentasa / Lialda / Apriso)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Ulcerative colitis — inflammation and ulceration of the lining of the large bowel
Metoprolol (Lopressor (tartrate) / Toprol-XL (succinate))
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
High blood pressure, chest pain, heart failure, and the period after a heart attack
Paroxetine (Paxil / Paxil CR / Pexeva / Brisdelle)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Depression, obsessive-compulsive disorder, panic, social anxiety, generalised anxiety and post-traumatic stress; separately, at a much lower dose, menopausal hot flushes
Prednisolone (Prednisolone Sodium Phosphate / Orapred / Pediapred / Pred Forte / Hydeltrasol)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Inflammation and overactive immune responses, across a very wide range of conditions
Saxagliptin (Onglyza)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Type 2 diabetes — a tablet that makes the gut hormone signal last longer
Tadalafil (Cialis)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
An enlarged prostate causing a weak stream and frequent urination — and, in the same tablet, erectile dysfunction
Verapamil (Calan / Isoptin / Verelan / Verelan PM / Covera-HS)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Chest pain, a racing or irregular heartbeat, and high blood pressure
Buprenorphine (Subutex / Suboxone / Butrans / Belbuca / Sublocade)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Opioid use disorder, and severe long-term pain
Ceftriaxone (Rocephin)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Serious bacterial infections given by injection — pneumonia, meningitis, bloodstream, bone, urinary and sexually transmitted infection
Dexamethasone (Decadron / Dexamethasone Sodium Phosphate / Maxidex / Ozurdex / Hemady)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Severe inflammation and swelling — including brain swelling, croup, some cancers, and COVID-19 severe enough to need oxygen
Diclofenac (Voltaren, Cataflam, Voltaren Arthritis Pain (topical gel), Solaraze)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Arthritis pain and inflammation
Elasomeran (Spikevax)
RNA medicine or vaccineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
COVID-19 prevention in older adults and people at higher risk
Enoxaparin (Lovenox)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Preventing and treating blood clots in the legs and lungs, and in heart attacks
Epinephrine (EpiPen / Auvi-Q / Adrenalin / neffy)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
A severe allergic reaction — the adrenaline pen
Fentanyl (Sublimaze (injection, NDA 016619, 1968); Duragesic (transdermal patch, NDA 019813, 1990); Actiq (oral transmucosal lozenge, NDA 020747, 1998); Fentora, Subsys, Abstral, Lazanda)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
A hospital anaesthetic and a patch for severe chronic pain. Separately, illicitly manufactured fentanyl is the drug involved in most American overdose deaths, and it is increasingly pressed into counterfeit pills
Filgrastim (Neupogen)
Protein medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Rebuilding infection-fighting white cells knocked down by chemotherapy
Finerenone (Kerendia)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Kidney disease caused by type 2 diabetes, and heart failure with a normal or near-normal pumping fraction
Glyburide (Diabeta / Micronase / Glynase PresTab (glibenclamide outside the United States))
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Type 2 diabetes — the strongest and longest-acting of the old sulfonylurea tablets
Hydralazine (Apresoline / Dralzine; as a fixed combination with isosorbide dinitrate, BiDil)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
High blood pressure, including when it must be brought down urgently; and, combined with a nitrate, heart failure
Hydroxychloroquine (Plaquenil / Sovuna)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Lupus, rheumatoid arthritis, and malaria where the parasite is still susceptible
Isosorbide Dinitrate (Isordil / Dilatrate-SR / Sorbitrate; as a fixed combination with hydralazine, BiDil)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Preventing angina — chest pain from narrowed heart arteries
Ketoconazole (Nizoral / Nizoral Anti-Dandruff / Extina / Xolegel / Ketoconazole shampoo 2%)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Dandruff and seborrhoeic dermatitis, and the pale or dark patches of tinea versicolor
Levetiracetam (Keppra)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Epilepsy, including focal seizures and generalised seizures
Lidocaine (Xylocaine)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Numbing part of the body for a procedure, and steadying a dangerously fast heart rhythm
Lumasiran (Oxlumo)
RNA-silencing medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Primary hyperoxaluria type 1 — a genetic cause of kidney stones and kidney failure
Nedosiran (Rivfloza)
RNA-silencing medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Primary hyperoxaluria type 1 — a genetic cause of kidney stones and kidney failure
Ondansetron (Zofran / Zofran ODT / Zuplenz)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Being sick, or feeling sick, after chemotherapy, radiotherapy or an operation
Patisiran (Onpattro)
RNA-silencing medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Nerve damage caused by inherited transthyretin amyloidosis
Phytonadione (Vitamin K1) (Mephyton / AquaMEPHYTON / Konakion)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Bleeding, or a risk of bleeding, because the body cannot finish building four of its clotting proteins — from warfarin, from a newborn gut that has not started making vitamin K yet, or from a condition that stops fat being absorbed
Pitavastatin (Livalo / Zypitamag / Nikita)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
High cholesterol
Raloxifene (Evista)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Thinning bones after menopause, and lowering the chance of developing one type of breast cancer
Rivaroxaban (Xarelto)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Preventing stroke in an irregular heartbeat, treating and preventing clots, and reducing events in stable artery disease
Tacrolimus (Prograf / Astagraf XL / Envarsus XR / Protopic)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Stopping the body rejecting a transplanted organ, and severe eczema that has not responded to steroid creams
Testosterone enanthate (Delatestryl, Xyosted; also sold as generic testosterone enanthate injection)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Testosterone replacement for men whose testicles or pituitary do not make enough
Ticagrelor (Brilinta)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Preventing heart attacks, strokes and stent clots after a heart attack or unstable angina
Trazodone (Desyrel / Oleptro (both discontinued as brands))
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Depression — although most people who are given it are taking it to sleep, which is not a licensed use
Adapalene (Differin / Differin Gel 0.1% (over the counter) / Epiduo (with benzoyl peroxide))
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Acne
Argatroban (Argatroban in 0.9% Sodium Chloride)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Preventing and treating clots in people who have had a dangerous immune reaction to heparin
Aripiprazole (Abilify)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Schizophrenia, bipolar disorder, depression that has not responded to an antidepressant alone, irritability in autism, and Tourette disorder
Azathioprine (Imuran / Azasan)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Stopping the immune system rejecting a transplanted kidney, and severe rheumatoid arthritis that has not responded to other treatment
Bupropion (Wellbutrin / Zyban)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Depression, and help with quitting smoking
Calcipotriene (Dovonex / Sorilux / Calcitrene / Taclonex (with betamethasone dipropionate))
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Plaque psoriasis — the raised, red, scaly patches
Calcitriol (Rocaltrol / Calcijex / Vectical)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Low calcium and overactive parathyroid glands caused by kidney failure, and low calcium caused by absent parathyroid hormone
Caplacizumab (Cablivi)
Antibody medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Stopping the microscopic clots of acquired TTP by cutting the tether that platelets are being dragged onto
Cariprazine (Vraylar)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Schizophrenia, both phases of bipolar I disorder, and depression that has not responded to an antidepressant alone
Chlorpheniramine (Chlor-Trimeton / Allergy Relief)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Sneezing, runny nose and itchy eyes — the old allergy tablet
Clopidogrel (Plavix)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Preventing clots after a heart attack, a stent, a stroke, or in blocked leg arteries
Clozapine (Clozaril, FazaClo, Versacloz)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
The antipsychotic used when others have failed, and the only one shown to reduce suicide risk in schizophrenia
Dextromethorphan (Sold over the counter in hundreds of cough products. Prescription combinations: Nuedexta (with quinidine, NDA 021879, 2010) and Auvelity (with bupropion, NDA 215430, 2022))
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
The cough suppressant in most supermarket cough syrups. At many times that dose it is a dissociative, and the same molecule is now half of a prescription antidepressant
Diltiazem (Cardizem / Cardizem CD / Cardizem LA / Tiadylt / Cartia XT)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Chest pain from narrowed or spasming arteries, high blood pressure, and a heart racing out of rhythm
Dolutegravir (Tivicay / Tivicay PD)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
HIV-1 infection, as part of a combination regimen
Emicizumab (Hemlibra)
Antibody medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
A subcutaneous injection, given as rarely as monthly, that stops the joint and muscle bleeds of haemophilia A without replacing the missing clotting factor
Eplontersen (Wainua)
Gene-silencing medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Hereditary ATTR Amyloidosis with Nerve Damage
Esketamine (Spravato)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Depression that has not responded to at least two other antidepressants
Fitusiran (Qfitlia)
RNA-silencing medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Haemophilia A or B, including when factor replacement no longer works
Fluvastatin (Lescol / Lescol XL)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
High cholesterol, and reducing the chance of needing a stent or a bypass in people who already have coronary disease
Glimepiride (Amaryl)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Type 2 diabetes — the sulfonylurea with the largest outcome trial behind it
Glipizide (Glucotrol / Glucotrol XL)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Type 2 diabetes — a tablet that squeezes more insulin out of the pancreas