Semax / Selank

Evidence: ★★☆☆☆ · Status: Not Approved

In plain English

Russian nasal-spray peptides — Semax for focus and brain-protection, Selank for calm-focus. Boost the brain's growth factors; mostly Russian clinical use.

How it works

Semax (ACTH4-10 analog) raises BDNF/NGF and modulates dopamine — focus/neuroprotection. Selank (tuftsin analog) modulates GABA/serotonin and BDNF — anxiolytic without sedation.

Molecular target & official sources

BDNF (NCBI Gene) · Semax (PubChem CID 108987)

Bottom line

Interesting, well-tolerated; evidence is largely non-Western.

Helps with: Focus & Cognition · Stress & Anxiety

Stacks with

Shares a pathway — often paired with: Caffeine, Modafinil / Armodafinil, EPO (Erythropoietin), Amphetamine (Adderall) / Lisdexamfetamine (Vyvanse).

Availability & where to buy

Not widely approved. Not approved for general sale in most markets (Singapore included). Grey-market only — dose, purity and legality uncertain.

How it works: the PI3K/Akt growth factor pathway →