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Quercetin + Dasatinib (D+Q)

Evidence: ★★★☆☆ · Status: OTC Supplement, Controlled, Prescription

💡 Did you know? The senolytic combo dasatinib + quercetin is taken in short 'hit and run' bursts — a couple of days on, then off — to clear 'zombie' cells.

In plain English

Two zombie-cell killers that cover different cell types together. Dasatinib is a real leukemia chemo drug (prescription, serious) — this combo belongs under medical supervision, not DIY.

How it works

The original senolytic cocktail. Dasatinib (a tyrosine-kinase inhibitor, ABL1/SRC) kills senescent fat-cell progenitors; quercetin (BCL-2 / PI3K inhibitor) kills senescent endothelial cells — complementary coverage.

Molecular target & official sources

ABL1 (NCBI Gene) · Dasatinib (PubChem CID 3062316) · Quercetin (PubChem CID 5280343)

Bottom line

Foundational senolytic research; dasatinib's toxicity means clinician-only.

Helps with: Live Longer

Stacks with

Shares a pathway — often paired with: Rapamycin (Sirolimus), EPO (Erythropoietin), Tesamorelin (Egrifta), Human Growth Hormone (Somatropin).

Availability & where to buy

Controlled substance. A controlled substance in most countries — illegal to buy, sell or possess without authorisation (in Singapore: HSA / CNB). Education only.

How it works: the PI3K/Akt growth factor pathway →

Common questions

Does Quercetin + Dasatinib (D+Q) actually work?

Human-evidence rating: 3 of 5. Foundational senolytic research; dasatinib's toxicity means clinician-only.

Is Quercetin + Dasatinib (D+Q) legal or approved?

Regulatory status: OTC Supplement, Controlled, Prescription.