MGF / PEG-MGF

Evidence: ★★☆☆☆ · Status: Not Approved

In plain English

The local signal muscle releases after damage to call in repair stem cells. Injected to try to boost recovery; mostly animal data.

How it works

Mechano-Growth Factor, a splice variant of IGF-1 (IGF1) released by damaged muscle, activating satellite (stem) cells for repair; PEGylation extends half-life.

Molecular target & official sources

IGF1 (NCBI Gene) · Frontiers peptide review

Bottom line

Interesting muscle-repair biology; unproven in humans.

Helps with: Build Muscle & Strength · Recover Faster · Hormones & Testosterone

Stacks with

Shares a pathway — often paired with: EPO (Erythropoietin), Tesamorelin (Egrifta), Human Growth Hormone (Somatropin), Insulin (anabolic misuse).

Availability & where to buy

Not widely approved. Not approved for general sale in most markets (Singapore included). Grey-market only — dose, purity and legality uncertain.

How it works: the PI3K/Akt growth factor pathway →