Melanotan II
Evidence: ★★☆☆☆ · Status: Not Approved
In plain English
Tans skin and boosts libido by hitting melanocortin receptors — but it also darkens moles and its long-term safety (including melanoma concern) is unknown.
How it works
Non-selective melanocortin agonist (MC1R tanning + MC4R libido/appetite); darkens skin and raises libido.
Molecular target & official sources
MC1R melanocortin 1 receptor (NCBI Gene) · Melanotan II (PubChem CID 92432)
Watch out
New/changing moles, nausea, unregulated purity.
Bottom line
Effective tanning/libido effect, real unresolved safety questions.
Helps with: Lose Fat · Hormones & Testosterone · Sexual Health · Skin & Hair
Stacks with
Shares a pathway — often paired with: PT-141 (Bremelanotide / Vyleesi), Setmelanotide (Imcivree), KPV.
Availability & where to buy
Not widely approved. Not approved for general sale in most markets (Singapore included). Grey-market only — dose, purity and legality uncertain.
How it works: the Melanocortin pathway →
Compare Melanotan II
- Melanotan II vs Testosterone (TRT)
- Melanotan II vs Finasteride / Dutasteride
- Melanotan II vs PDE-5 Inhibitors (Sildenafil / Tadalafil)
- Melanotan II vs Anastrozole / Exemestane (Aromatase Inhibitors)
- Melanotan II vs PT-141 (Bremelanotide / Vyleesi)
- Melanotan II vs Tongkat Ali (Eurycoma longifolia)
- Melanotan II vs Nandrolone (Deca-Durabolin)
Common questions
Does Melanotan II actually work?
Human-evidence rating: 2 of 5. Effective tanning/libido effect, real unresolved safety questions.
What are the risks or side effects of Melanotan II?
New/changing moles, nausea, unregulated purity.
Is Melanotan II legal or approved?
Regulatory status: Not Approved.