Bromantane

Evidence: ★★☆☆☆ · Status: Not Approved

In plain English

Increases how much dopamine you make (not just release), giving calm stimulation. Russian anti-fatigue drug; limited Western data.

How it works

"Actoprotector" that upregulates tyrosine hydroxylase (TH) gene expression → increased dopamine synthesis, combined with mild anxiolysis — stimulation without the crash.

Molecular target & official sources

TH (NCBI Gene) · Bromantane (PubChem CID 108030)

Bottom line

Novel mechanism; sparse independent evidence.

Helps with: Focus & Cognition · Stress & Anxiety

Stacks with

Shares a pathway — often paired with: Caffeine, Modafinil / Armodafinil, Amphetamine (Adderall) / Lisdexamfetamine (Vyvanse), Methylphenidate (Ritalin).

Availability & where to buy

Not widely approved. Not approved for general sale in most markets (Singapore included). Grey-market only — dose, purity and legality uncertain.

How it works: the Monoamines pathway →