Browse medicines, page 2 of 40
Some records contain detailed evidence; others currently contain only basic identity and regulatory information. Reviewed conclusions appear only when they are available for a specific use and group of people.
Showing 61–120 of 2,365 records
Bempedoic acid (Nexletol (Nexlizet in combination with ezetimibe))
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
High cholesterol and cardiovascular risk in people who cannot tolerate a statin
Carvedilol (Coreg)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
A weakened, failing heart, and the months after a heart attack
Clomiphene (Clomid, Serophene, Milophene; clomifene citrate outside the United States)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Ovulation induction in women — and, off-label, restarting testosterone production in men
Ostarine (Enobosarm (development name); also sold as MK-2866 and GTx-024)
Small chemical medicineIn Phase 3 testingDetailed recordUse listed on the medicine record
Muscle wasting — investigational only, and it failed its phase 3
Piracetam (Nootropil; also Myocalm, Lucetam, Nootropyl and many national names)
Small chemical medicineApproved in the European Union (EMA)Detailed recordUse listed on the medicine record
A prescription drug for a rare jerking movement disorder, sold in the US as a supplement
Prednisone (Deltasone / Orasone)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
The short steroid course — for an asthma attack, a bad flare-up, a severe allergic reaction
Roflumilast (Daliresp / Zoryve)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
A daily tablet that damps down inflammation in severe smokers’ lung disease, and — as a cream — a treatment for psoriasis and eczema
Rosiglitazone (Avandia)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
A tablet for type 2 diabetes that makes the body more sensitive to insulin
Simvastatin (Zocor / Flolipid)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
High cholesterol, and the prevention of heart attacks and strokes in people who already have vascular disease or diabetes
Tiotropium (Spiriva Respimat / Spiriva HandiHaler / Spiriva)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
A once-daily inhaler that blocks the nerve signal telling the airway to tighten
Alosetron (Lotronex)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
A tablet for severe diarrhoea-predominant irritable bowel syndrome in women, prescribed only under a special programme
Bisoprolol (Zebeta)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
High blood pressure — and, in most of the world, a weakened heart
Colchicine (Colcrys / Mitigare / Lodoco)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Gout attacks, familial Mediterranean fever, and — for one specific product — reducing heart attack and stroke risk in established artery disease
Ezetimibe (Zetia (Ezetrol outside the United States))
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
High cholesterol, usually alongside a statin
Hydrochlorothiazide (Microzide, and dozens of fixed combinations)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
High blood pressure, and fluid retention
Lansoprazole (Prevacid / Prevacid SoluTab / Prevacid 24HR)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Stomach and duodenal ulcers, reflux that has damaged the gullet, and prevention of ulcers caused by anti-inflammatory painkillers
Lovastatin (Mevacor / Altoprev)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
High cholesterol, and the prevention of a first heart attack in people with average cholesterol and low HDL
Methylene blue (ProvayBlue (injection); methylthioninium chloride. The Alzheimer derivative is hydromethylthionine mesylate, formerly TRx0237 and LMTM)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
An antidote for a blood disorder, taken off-label in tiny doses as a nootropic
Oxandrolone (Oxandrin)
Small chemical medicineWithdrawn from the marketDetailed recordUse listed on the medicine record
Weight gain after severe illness, injury or burns — approved, and no longer marketed in the United States
5-MeO-DMT (5-Methoxy-N,N-dimethyltryptamine) (GH001, a vaporised synthetic formulation in clinical development; the INN assigned to the molecule is mebufotenin)
Small chemical medicineControlled substance; no approved US useDetailed recordUse listed on the medicine record
Nothing approved. A synthetic inhaled version is in trials for depression that has not responded to other drugs; the substance itself is Schedule I
Azithromycin (Zithromax / Z-Pak)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Chest, throat, skin and sexually transmitted bacterial infections, and mass treatment for trachoma
Bivalirudin (Angiomax)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Preventing clots during a procedure to open a blocked heart artery
Bromantane (Ladasten; also written bromantan and, in the doping literature, bromontan)
Small chemical medicineDietary supplement; not FDA-approved as a medicineDetailed recordUse listed on the medicine record
A Russian anti-fatigue drug that became a doping case before most people had heard of it
Cefdinir (Omnicef)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Ear infections in children, and chest, sinus, throat and skin infections
Diphenhydramine (Benadryl / Allergy Relief / Nighttime Sleep Aid)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Allergic reactions, itching and hives, motion sickness, and trouble falling asleep
Fluconazole (Diflucan)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Thrush and other yeast infections, and fungal meningitis in people with advanced HIV
Fluoxetine (Prozac / Prozac Weekly / Sarafem / Selfemra)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Depression, obsessive-compulsive disorder, bulimia and panic attacks
Ibogaine (No marketed product. Historically sold in France as Lambarène, a Tabernanthe extract tonic, until 1966)
Small chemical medicineControlled substance; no approved US useDetailed recordUse listed on the medicine record
Nothing approved. People travel to clinics outside the United States to take it for opioid withdrawal, and the published observational studies of those clinics are the entire clinical evidence base
Isosorbide Mononitrate (Imdur / Monoket / Ismo)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Chest pain from narrowed heart arteries, prevented rather than stopped
Ligandrol (LGD-4033; developed as VK5211)
Small chemical medicineIn Phase 2 testingDetailed recordUse listed on the medicine record
Muscle loss after hip fracture — investigational only, and development stopped
Mirabegron (Myrbetriq)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
An overactive bladder — sudden urgency, going too often, and leaking — for people who cannot tolerate or do not want an anticholinergic drug
Oxycodone (OxyContin / Roxicodone / Xtampza ER / RoxyBond / Oxaydo)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Pain severe enough to need an opioid, when other treatments have not worked
Ranolazine (Ranexa / Aspruzyo Sprinkle)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Chest pain that keeps happening despite the usual drugs
Simeprevir (Olysio)
Small chemical medicineWithdrawn from the marketDetailed recordUse listed on the medicine record
Long-standing hepatitis C infection, genotype 1 or 4 — a drug that is no longer sold in the United States
Boldenone (Equipoise, Boldebal, Ganabol; sold as boldenone undecylenate ("EQ"))
Small chemical medicineControlled substance; no approved US useDetailed recordUse listed on the medicine record
A horse steroid used by people — no human approval anywhere
Cefepime (Maxipime)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Serious hospital infections, including pneumonia and fever in patients whose white cell count has collapsed
Celecoxib (Celebrex, Elyxyb)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Arthritis pain and inflammation, with less stomach damage
Ciprofloxacin (Cipro / Cipro XR)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Serious bacterial infections of the kidney, gut, bone and abdomen, and anthrax after exposure
Cyclosporine (Sandimmune / Neoral / Gengraf / Restasis / Cequa / Verkazia)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Preventing rejection of a transplanted organ, severe rheumatoid arthritis and psoriasis, and chronic dry eye
DMT (N,N-Dimethyltryptamine) (No marketed product. The principal psychoactive constituent of ayahuasca; SPL026 and similar synthetic DMT fumarate formulations are in clinical trials)
Small chemical medicineControlled substance; no approved US useDetailed recordUse listed on the medicine record
Nothing approved. A single randomised trial of ayahuasca in 29 people with depression that had not responded to other treatments
Duloxetine (Cymbalta / Drizalma Sprinkle / Yentreve (European Union, stress urinary incontinence))
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Depression, generalised anxiety, nerve pain from diabetes, fibromyalgia and long-term back or joint pain
Dutasteride (Avodart)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
An enlarged prostate, where the aim is to shrink the gland rather than relax it
Famotidine (Pepcid / Pepcid AC)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Heartburn and acid indigestion, and healing of stomach and duodenal ulcers
Finasteride (Proscar)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
An enlarged prostate causing a weak stream and frequent urination, where the aim is to shrink the gland rather than relax it
JWH-018 and the Synthetic Cannabinoid Class (K2 / Spice) (Sold as herbal incense under hundreds of brand names — Spice, K2, AK-47 24 Karat Gold, Scooby Snax — never under a chemical name)
Small chemical medicineControlled substance; no approved US useDetailed recordUse listed on the medicine record
Nothing. These are laboratory research chemicals sprayed onto plant matter and sold as incense, and the compounds in them change faster than the law can list them
Leflunomide (Arava)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Active rheumatoid arthritis
Levothyroxine (Synthroid / Euthyrox / Levoxyl / Unithroid / Tirosint)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
An underactive thyroid gland
Linezolid (Zyvox)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Serious infections caused by resistant Gram-positive bacteria, including MRSA and vancomycin-resistant enterococci
Mesalamine (Rowasa / Canasa / Asacol / Pentasa / Lialda / Apriso)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Ulcerative colitis — inflammation and ulceration of the lining of the large bowel
Metoprolol (Lopressor (tartrate) / Toprol-XL (succinate))
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
High blood pressure, chest pain, heart failure, and the period after a heart attack
Paroxetine (Paxil / Paxil CR / Pexeva / Brisdelle)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Depression, obsessive-compulsive disorder, panic, social anxiety, generalised anxiety and post-traumatic stress; separately, at a much lower dose, menopausal hot flushes
Prednisolone (Prednisolone Sodium Phosphate / Orapred / Pediapred / Pred Forte / Hydeltrasol)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Inflammation and overactive immune responses, across a very wide range of conditions
Psilocin (4-Hydroxy-N,N-dimethyltryptamine) (No product. It is the active metabolite of psilocybin, which is the compound formulated in every clinical trial)
Small chemical medicineControlled substance; no approved US useDetailed recordUse listed on the medicine record
Nothing. It is the molecule that psilocybin turns into in the body, and it is the one that does the work — every psilocybin trial result on this site is really a psilocin result
Saxagliptin (Onglyza)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Type 2 diabetes — a tablet that makes the gut hormone signal last longer
Tadalafil (Cialis)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
An enlarged prostate causing a weak stream and frequent urination — and, in the same tablet, erectile dysfunction
Verapamil (Calan / Isoptin / Verelan / Verelan PM / Covera-HS)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Chest pain, a racing or irregular heartbeat, and high blood pressure
Benfluorex (Mediator)
Small chemical medicineWithdrawn from the marketDetailed recordUse listed on the medicine record
A tablet marketed for blood fats and for weight in diabetes, widely prescribed in France
Buprenorphine (Subutex / Suboxone / Butrans / Belbuca / Sublocade)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Opioid use disorder, and severe long-term pain
Ceftriaxone (Rocephin)
Small chemical medicineApproved in the United States (FDA)Detailed recordUse listed on the medicine record
Serious bacterial infections given by injection — pneumonia, meningitis, bloodstream, bone, urinary and sexually transmitted infection
Cerivastatin (Baycol / Lipobay)
Small chemical medicineWithdrawn from the marketDetailed recordUse listed on the medicine record
A cholesterol-lowering statin