Browse medicines, page 2 of 3
Some records contain detailed evidence; others currently contain only basic identity and regulatory information. Reviewed conclusions appear only when they are available for a specific use and group of people.
Showing 61–120 of 134 records
Atoltivimab (Inmazeb)
Antibody medicineApproved in the United States (FDA)Expanded recordUse listed on the medicine record
Infection caused by Orthoebolavirus zairense
Axatilimab (Niktimvo)
Antibody medicineLaboratory or animal-stage researchExpanded recordUse listed on the medicine record
Chronic graft-versus-host disease (cGVHD) after failure of at least two prior lines of systemic therapy
Belimumab (Benlysta)
Antibody medicineApproved in the United States (FDA)Expanded recordUse listed on the medicine record
Patients 5 years of age and older
Bezlotoxumab (Zinplava)
Antibody medicineApproved in the United States (FDA)Expanded recordUse listed on the medicine record
Recurrence of Clostridioides difficile infection
Blinatumomab (Blincyto)
Antibody medicineApproved in the United States (FDA)Expanded recordUse listed on the medicine record
Adult and pediatric patients one month and older
Burosumab (Crysvita)
Antibody medicineLaboratory or animal-stage researchExpanded recordUse listed on the medicine record
X-linked hypophosphatemia
Clesrovimab (Enflonsia)
Antibody medicineLaboratory or animal-stage researchExpanded recordUse listed on the medicine record
RSV lower respiratory tract disease in neonates and infants who are born during or entering their first RSV season
Crovalimab (Piasky)
Antibody medicineLaboratory or animal-stage researchExpanded recordUse listed on the medicine record
Adult and pediatric patients 13 years and older with paroxysmal nocturnal hemoglobinuria (PNH) and body weight of at least 40 kg
Daclizumab (Zinbryta)
Antibody medicineApproved in the United States (FDA)Expanded recordDalotuzumab (Cell Energy Performance Drops 2048 / Growth Hormone Drops 2160)
Antibody medicineDietary supplement; not FDA-approved as a medicineExpanded recordUse listed on the medicine record
Feeling tired, listless, easily fatigued, or experiencing reduced strength, difficulty concentrating, or a lack of motivation
Daratumumab (Darzalex / Darzalex IV)
Antibody medicineApproved in the United States (FDA)Expanded recordUse listed on the medicine record
The treatment of adult patients with multiple myeloma
Elotuzumab (Empliciti)
Antibody medicineApproved in the United States (FDA)Expanded recordUse listed on the medicine record
• EMPLICITI is indicated in combination with lenalidomide and dexamethasone for the treatment of adult patients with multiple myeloma who have received one to three prior therapies. • EMPLICITI is indicated in combination with pomalidomide and dexamethasone for the treatment of adult patients with multiple myeloma who have received at least two prior therapies including lenalidomide and a proteasome inhibitor.
Elranatamab (Elrexfio)
Antibody medicineApproved in the United States (FDA)Expanded recordUse listed on the medicine record
ELREXFIO is indicated for the treatment of adult patients with relapsed or refractory multiple myeloma who have received at least four prior lines of therapy, including a proteasome inhibitor, an immunomodulatory agent, and an anti-CD38 monoclonal antibody. This indication is approved under accelerated approval based on response rate and durability of response [see Clinical Studies (14) ] . Continued approval for this indication may be contingent upon verification of clinical benefit in a confirmatory trial(s).
Faricimab (Vabysmo)
Antibody medicineLaboratory or animal-stage researchExpanded recordUse listed on the medicine record
The treatment of patients
Fremanezumab (Ajovy)
Antibody medicineLaboratory or animal-stage researchExpanded recordUse listed on the medicine record
AJOVY is indicated for: the preventive treatment of migraine in adults, and the preventive treatment of episodic migraine in pediatric patients who are 6 to 17 years of age and who weigh 45 kg or more. AJOVY is a calcitonin gene-related peptide antagonist indicated for: the preventive treatment of migraine in adults, and the preventive treatment of episodic migraine in pediatric patients who are 6 to 17 years of age and who weigh 45 kg or more. ( 1 )
Galcanezumab (Emgality)
Antibody medicineLaboratory or animal-stage researchExpanded recordUse listed on the medicine record
Episodic cluster headache
Glofitamab (Columvi)
Antibody medicineLaboratory or animal-stage researchExpanded recordUse listed on the medicine record
COLUMVI is indicated for the treatment of adult patients with relapsed or refractory diffuse large B-cell lymphoma, not otherwise specified (DLBCL, NOS) or large B-cell lymphoma (LBCL) arising from follicular lymphoma, after two or more lines of systemic therapy. This indication is approved under accelerated approval based on response rate and durability of response [see Clinical Studies (14.1) ] . Continued approval for this indication may be contingent upon verification and description of clinical benefit in a confirmatory trial(s).
Imciromab (Myoscint)
Antibody medicineApproved in the United States (FDA)Expanded recordMargetuximab (Margenza)
Antibody medicineLaboratory or animal-stage researchExpanded recordUse listed on the medicine record
Metastatic HER2-positive breast cancer who have received two or more prior anti-HER2 regimens, at least one of which was
Narsoplimab (Yartemlea)
Antibody medicineLaboratory or animal-stage researchExpanded recordUse listed on the medicine record
Adult and pediatric patients 2 years of age and older with hematopoietic stem cell transplant-associated thrombotic microangiopathy
Nemolizumab (Nemluvio)
Antibody medicineLaboratory or animal-stage researchExpanded recordUse listed on the medicine record
Prurigo nodularis
Olaratumab (Lartruvo)
Antibody medicineApproved in the United States (FDA)Expanded recordPalivizumab (Synagis)
Antibody medicineApproved in the United States (FDA)Expanded recordUse listed on the medicine record
Serious lower respiratory tract disease caused by respiratory syncytial virus
Penpulimab
Antibody medicineLaboratory or animal-stage researchExpanded recordUse listed on the medicine record
Penpulimab-kcqx is a programmed death receptor-1 (PD-1)-blocking antibody indicated: in combination with either cisplatin or carboplatin and gemcitabine for the first-line treatment of adults with recurrent or metastatic non-keratinizing nasopharyngeal carcinoma (NPC) ( 1.1 ) as a single agent for the treatment of adults with metastatic non-keratinizing NPC with disease progression on or after platinum-based chemotherapy and at least one other prior line of therapy.
Ravulizumab (Ultomiris)
Antibody medicineLaboratory or animal-stage researchExpanded recordUse listed on the medicine record
ULTOMIRIS is a complement inhibitor indicated for: the treatment of adult and pediatric patients one month of age and older with paroxysmal nocturnal hemoglobinuria (PNH). ( 1.1 ) the treatment of adult and pediatric patients one month of age and older with atypical hemolytic uremic syndrome (aHUS) to inhibit complement-mediated thrombotic microangiopathy (TMA). ( 1.2 ) Limitations of Use: ULTOMIRIS is not indicated for the treatment of patients with Shiga toxin E. coli related hemolytic uremic syndrome (STEC-HUS).
Relatlimab (Opdualag)
Antibody medicineLaboratory or animal-stage researchExpanded recordUse listed on the medicine record
Adult and pediatric patients 12 years of age or older with unresectable or metastatic melanoma
Satralizumab (Enspryng)
Antibody medicineApproved in the United States (FDA)Expanded recordUse listed on the medicine record
Neuromyelitis optica spectrum disorder
Teclistamab (Tecvayli)
Antibody medicineLaboratory or animal-stage researchExpanded recordUse listed on the medicine record
Relapsed or refractory multiple myeloma
Vilobelimab (Gohibic)
Antibody medicineFDA accelerated approval (based on an earlier result expected to predict benefit; follow-up evidence may be required)Expanded recordAbciximab (Reopro)
Antibody medicineApproved in the United States (FDA)Expanded recordCosibelimab (Unloxcyt)
Antibody medicineLaboratory or animal-stage researchExpanded recordUse listed on the medicine record
UNLOXCYT is indicated for the treatment of adults with metastatic cutaneous squamous cell carcinoma (mCSCC) or locally advanced CSCC (laCSCC) who are not candidates for curative surgery or curative radiation. UNLOXCYT is a programmed death ligand-1 (PD-L1) blocking antibody indicated for the treatment of adults with metastatic cutaneous squamous cell carcinoma (mCSCC) or locally advanced CSCC (laCSCC) who are not candidates for curative surgery or curative radiation.
Depemokimab (Exdensur)
Antibody medicineLaboratory or animal-stage researchExpanded recordUse listed on the medicine record
Severe asthma characterized by an eosinophilic phenotype
Eculizumab (Soliris / Epysqli / Bkemv)
Antibody medicineApproved in the United States (FDA)Expanded recordUse listed on the medicine record
SOLIRIS is a complement inhibitor indicated for: the treatment of patients with paroxysmal nocturnal hemoglobinuria (PNH) to reduce hemolysis. ( 1.1 ) the treatment of patients with atypical hemolytic uremic syndrome (aHUS) to inhibit complement-mediated thrombotic microangiopathy. ( 1.2 ) Limitation of Use SOLIRIS is not indicated for the treatment of patients with Shiga toxin E. coli related hemolytic uremic syndrome (STEC-HUS).
Emapalumab (Gamifant)
Antibody medicineLaboratory or animal-stage researchExpanded recordUse listed on the medicine record
GAMIFANT is indicated for the treatment of: adult and pediatric patients with primary hemophagocytic lymphohistiocytosis (HLH) with refractory, recurrent or progressive disease or intolerance with conventional HLH therapy. adult and pediatric patients with HLH/macrophage activation syndrome (MAS) in known or suspected Still’s disease, including systemic Juvenile Idiopathic Arthritis (sJIA), with an inadequate response or intolerance to glucocorticoids, or with recurrent MAS.
Epcoritamab (Epkinly)
Antibody medicineLaboratory or animal-stage researchExpanded recordUse listed on the medicine record
EPKINLY is a bispecific CD20-directed CD3 T-cell engager indicated: For the treatment of adult patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL), not otherwise specified, including DLBCL arising from indolent lymphoma, and high-grade B-cell lymphoma after two or more lines of systemic therapy. ( 1.1 ) This indication is approved under accelerated approval based on response rate and durability of response. Continued approval for this indication may be contingent upon verification and description of clinical benefit in a confirmatory trial(s).
Isatuximab (Sarclisa / Sarclisa Escena)
Antibody medicineLaboratory or animal-stage researchExpanded recordUse listed on the medicine record
SARCLISA ESCENA is indicated: in combination with pomalidomide and dexamethasone, for the treatment of adult patients with multiple myeloma who have received at least 1 prior line of therapy including lenalidomide and a proteasome inhibitor. in combination with carfilzomib and dexamethasone, for the treatment of adult patients with relapsed or refractory multiple myeloma who have received 1 to 3 prior lines of therapy.
Obinutuzumab (Gazyva)
Antibody medicineApproved in the United States (FDA)Expanded recordUse listed on the medicine record
Previously untreated chronic lymphocytic leukemia
Odesivimab (Inmazeb)
Antibody medicineApproved in the United States (FDA)Expanded recordUse listed on the medicine record
Infection caused by Orthoebolavirus zairense
Pertuzumab (Perjeta)
Antibody medicineApproved in the United States (FDA)Expanded recordUse listed on the medicine record
HER2-positive metastatic breast cancer who have not received prior anti-HER2 therapy or chemotherapy for metastatic disease [see
Pozelimab (Veopoz)
Antibody medicineLaboratory or animal-stage researchExpanded recordUse listed on the medicine record
Adult and pediatric patients 1 year of age and older with CD55-deficient protein-losing enteropathy (PLE), also known as CHAPLE disease
Raxibacumab
Antibody medicineApproved in the United States (FDA)Expanded recordUse listed on the medicine record
Inhalational anthrax due to Bacillus anthracis
Sibeprenlimab (Voyxact)
Antibody medicineLaboratory or animal-stage researchExpanded recordUse listed on the medicine record
Proteinuria
Tafasitamab (Monjuvi)
Antibody medicineLaboratory or animal-stage researchExpanded recordUse listed on the medicine record
MONJUVI is a CD19-directed cytolytic antibody indicated: in combination with lenalidomide for the treatment of adult patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL) not otherwise specified, including DLBCL arising from low grade lymphoma, and who are not eligible for autologous stem cell transplant (ASCT). This indication is approved under accelerated approval based on overall response rate. Continued approval for this indication may be contingent upon verification and description of clinical benefit in a confirmatory trial(s).
Teplizumab (Tzield)
Antibody medicineLaboratory or animal-stage researchExpanded recordUse listed on the medicine record
TZIELD is indicated to [see Dosage and Administration (2.1) ]: Delay the onset of Stage 3 type 1 diabetes (T1D) in adult and pediatric patients 1 year of age and older with Stage 2 T1D. Delay the decline in endogenous insulin production in pediatric patients aged 8 to 17 years recently diagnosed with Stage 3 T1D. This indication is approved under accelerated approval based on evidence of reduced C-peptide decline [see Clinical Studies (14.2) ] . Continued approval for this indication may be contingent upon verification and description of clinical benefit in confirmatory trial(s).
Concizumab (Alhemo)
Antibody medicineApproved in the United States (FDA)Expanded recordUse listed on the medicine record
Routine prophylaxis to prevent or reduce the frequency of bleeding episodes
Crizanlizumab (Adakveo)
Antibody medicineLaboratory or animal-stage researchExpanded recordUse listed on the medicine record
The frequency of vaso-occlusive crises
Ipilimumab (Yervoy)
Antibody medicineApproved in the United States (FDA)Expanded recordUse listed on the medicine record
YERVOY is a human cytotoxic T-lymphocyte antigen 4 (CTLA-4)-blocking antibody indicated for: Melanoma • Treatment of unresectable or metastatic melanoma in adults and pediatric patients 12 years and older as a single agent or in combination with nivolumab. (1.1) • Adjuvant treatment of adult patients with cutaneous melanoma with pathologic involvement of regional lymph nodes of more than 1 mm who have undergone complete resection, including total lymphadenectomy.
Lebrikizumab (Ebglyss)
Antibody medicineLaboratory or animal-stage researchExpanded recordUse listed on the medicine record
Moderate-to-severe atopic dermatitis
Mirikizumab (Omvoh)
Antibody medicineLaboratory or animal-stage researchExpanded recordUse listed on the medicine record
OMVOH is indicated for the treatment of: moderately to severely active ulcerative colitis in adults. moderately to severely active Crohn's disease in adults. OMVOH TM is an interleukin-23 antagonist indicated for the treatment of: moderately to severely active ulcerative colitis in adults ( 1 ) moderately to severely active Crohn's disease in adults ( 1 )
Mogamulizumab (Poteligeo)
Antibody medicineLaboratory or animal-stage researchExpanded recordUse listed on the medicine record
Relapsed or refractory mycosis fungoides (MF) or Sézary syndrome (SS) after at least one prior systemic therapy
Mosunetuzumab (Lunsumio / Lunsumio Velo)
Antibody medicineLaboratory or animal-stage researchExpanded recordUse listed on the medicine record
Relapsed or refractory follicular lymphoma after two or more lines of systemic therapy
Necitumumab (Portrazza)
Antibody medicineApproved in the United States (FDA)Expanded recordNipocalimab (Imaavy)
Antibody medicineLaboratory or animal-stage researchExpanded recordUse listed on the medicine record
Generalized myasthenia gravis
Nirsevimab (Beyfortus)
Antibody medicineLaboratory or animal-stage researchExpanded recordUse listed on the medicine record
Respiratory Syncytial Virus (RSV) lower respiratory tract disease
Ofatumumab (Kesimpta / Arzerra)
Antibody medicineApproved in the United States (FDA)Expanded recordUse listed on the medicine record
KESIMPTA is indicated for the treatment of relapsing forms of multiple sclerosis (MS), to include clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease, in adults. KESIMPTA is a CD20-directed cytolytic antibody indicated for the treatment of relapsing forms of multiple sclerosis (MS), to include clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease, in adults. ( 1 )
Panitumumab (Vectibix)
Antibody medicineApproved in the United States (FDA)Expanded recordUse listed on the medicine record
KRAS G12C- mutated mCRC, as determined by an FDA-approved test, who have received prior treatment with fluoropyrimidine-
Retifanlimab (Zynyz)
Antibody medicineLaboratory or animal-stage researchExpanded recordUse listed on the medicine record
Locally recurrent or metastatic SCAC with disease progression on or intolerance to platinum-based chemotherapy
Sutimlimab (Enjaymo)
Antibody medicineLaboratory or animal-stage researchExpanded recordUse listed on the medicine record
Hemolysis
Tislelizumab (Tevimbra)
Antibody medicineLaboratory or animal-stage researchExpanded recordUse listed on the medicine record
Unresectable or metastatic esophageal squamous cell carcinoma (ESCC) after prior systemic chemotherapy that did not include a PD
Zolbetuximab (Vyloy)
Antibody medicineLaboratory or animal-stage researchExpanded recordUse listed on the medicine record
The first-line treatment of adults with locally advanced unresectable or metastatic human epidermal growth factor receptor 2 (HER2)‑negative