Medicine library

Browse medicines, page 5 of 8

Some records contain detailed evidence; others currently contain only basic identity and regulatory information. Reviewed conclusions appear only when they are available for a specific use and group of people.

Showing 241–300 of 475 records

Topiramate (Topamax / Trokendi XR / Qudexy XR)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Epilepsy, including focal and generalised seizures and Lennox-Gastaut syndrome, and prevention of migraine attacks
Trazodone (Desyrel / Oleptro (both discontinued as brands))
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Depression — although most people who are given it are taking it to sleep, which is not a licensed use
Zilebesiran (ALN-AGT01 (investigational))
RNA-silencing medicineIn Phase 2 testingDetailed record
Use listed on the medicine record
High blood pressure, dosed twice a year instead of daily
Argatroban (Argatroban in 0.9% Sodium Chloride)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Preventing and treating clots in people who have had a dangerous immune reaction to heparin
Aripiprazole (Abilify)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Schizophrenia, bipolar disorder, depression that has not responded to an antidepressant alone, irritability in autism, and Tourette disorder
Azathioprine (Imuran / Azasan)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Stopping the immune system rejecting a transplanted kidney, and severe rheumatoid arthritis that has not responded to other treatment
Beclomethasone (Qvar / Qvar Redihaler / Qnasl / Beconase AQ / Vancenase AQ / Beclovent)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
A daily preventer inhaler for asthma, and a nasal spray for hay fever
Benzonatate (Tessalon)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
A cough, of any cause
Calcitriol (Rocaltrol / Calcijex / Vectical)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Low calcium and overactive parathyroid glands caused by kidney failure, and low calcium caused by absent parathyroid hormone
Cannabis (Plant Preparation) (Sold as flower, resin, concentrate and edible. Isolated delta-9-THC and cannabidiol have their own records on this site)
Nutritional or plant productControlled substance; no approved US useDetailed record
Use listed on the medicine record
Nothing approved as a plant. Used under state medical-cannabis programmes for chronic pain, chemotherapy nausea and multiple sclerosis spasticity, where the trial evidence is for isolated or standardised cannabinoids rather than for smoked flower
Caplacizumab (Cablivi)
Antibody medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Stopping the microscopic clots of acquired TTP by cutting the tether that platelets are being dragged onto
Chlorpheniramine (Chlor-Trimeton / Allergy Relief)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Sneezing, runny nose and itchy eyes — the old allergy tablet
Clopidogrel (Plavix)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Preventing clots after a heart attack, a stent, a stroke, or in blocked leg arteries
Clozapine (Clozaril, FazaClo, Versacloz)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
The antipsychotic used when others have failed, and the only one shown to reduce suicide risk in schizophrenia
Daclatasvir (Daklinza)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Long-standing hepatitis C infection, genotype 1 or 3
Dalteparin (Fragmin)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Preventing and treating blood clots, including the long-term treatment of clots in people with cancer
Dextromethorphan (Sold over the counter in hundreds of cough products. Prescription combinations: Nuedexta (with quinidine, NDA 021879, 2010) and Auvelity (with bupropion, NDA 215430, 2022))
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
The cough suppressant in most supermarket cough syrups. At many times that dose it is a dissociative, and the same molecule is now half of a prescription antidepressant
Dolutegravir (Tivicay / Tivicay PD)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
HIV-1 infection, as part of a combination regimen
Emicizumab (Hemlibra)
Antibody medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
A subcutaneous injection, given as rarely as monthly, that stops the joint and muscle bleeds of haemophilia A without replacing the missing clotting factor
Eplontersen (Wainua)
Gene-silencing medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Hereditary ATTR Amyloidosis with Nerve Damage
Esketamine (Spravato)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Depression that has not responded to at least two other antidepressants
Fluvastatin (Lescol / Lescol XL)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
High cholesterol, and reducing the chance of needing a stent or a bypass in people who already have coronary disease
Glimepiride (Amaryl)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Type 2 diabetes — the sulfonylurea with the largest outcome trial behind it
Glipizide (Glucotrol / Glucotrol XL)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Type 2 diabetes — a tablet that squeezes more insulin out of the pancreas
Haloperidol (Haldol)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Psychosis, and the tics of Tourette disorder
Hydroxyzine (Atarax / Vistaril)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Itching from allergy or hives, anxiety, and sedation before an anaesthetic
Ibutamoren (MK-677, also written MK-0677; ibutamoren mesylate)
Small chemical medicineIn Phase 2 testingDetailed record
Use listed on the medicine record
Age-related muscle loss and fracture recovery — investigational, and the programme ended
Indomethacin (Indocin, Tivorbex, Indocin IV)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Severe arthritis, gout attacks and inflamed shoulders
Lamivudine (Epivir for HIV-1 and Epivir-HBV for hepatitis B, at different strengths; also in Combivir, Epzicom, Triumeq and Dovato)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
HIV-1 infection and chronic hepatitis B
Latanoprost (Xalatan)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
High pressure inside the eye, and the nerve damage it causes
Losartan (Cozaar)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
High blood pressure, thickened heart muscle, and kidney damage from type 2 diabetes
Lovotibeglogene autotemcel (Lyfgenia)
Gene-editing or gene therapyApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Sickle cell disease with a history of severe pain crises
Metronidazole (Flagyl / MetroGel)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Infections caused by parasites and by bacteria that grow without oxygen, including bacterial vaginosis and trichomoniasis
Mometasone (Asmanex Twisthaler / Asmanex HFA / Nasonex / Elocon / Sinuva)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
A steroid that comes as an asthma inhaler, a hay-fever nasal spray, a skin cream and a sinus implant
Naproxen (Naprosyn, Anaprox, Aleve, Naprelan)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Pain, fever and inflammation, especially where it needs to last
Nitrous Oxide (Nitrous Oxide USP, approved as a prescription medical gas under several NDAs including NDA 205704 (2013). Entonox is the 50:50 nitrous oxide / oxygen mixture used for labour and procedural analgesia)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Used in operating theatres, dentistry and childbirth as a fast-on, fast-off anaesthetic and painkiller. The identical gas is sold in cream-charger cartridges with no restriction, and inhaling it repeatedly destroys vitamin B12
Nortriptyline (Pamelor / Aventyl — both discontinued as brands)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Depression — and, off-label, nerve pain, migraine prevention and helping people stop smoking
Olopatadine (Patanol / Pataday / Patanase)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Itchy, red, watering eyes from allergy
Oseltamivir (Tamiflu)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Flu, if started within two days of the first symptom
Pantoprazole (Protonix / Protonix IV)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Reflux that has damaged the lining of the gullet, and rare conditions that make the stomach produce far too much acid
Phenibut (β-Phenyl-GABA) (Fenibut, Anvifen, Noofen — prescription products in Russia, Latvia, Ukraine and Kazakhstan. In the United States it is sold in supplements under names such as Fenibut and β-phenyl-GABA)
Small chemical medicineDietary supplement; not FDA-approved as a medicineDetailed record
Use listed on the medicine record
An anxiety and sleep drug on prescription in Russia and Latvia. In the United States it is a supplement-aisle product that produces coma in about one in sixteen reported exposures
Phentermine (Adipex-P; also the phentermine half of Qsymia)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
A short-term prescription appetite suppressant
Pravastatin (Pravachol)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
High cholesterol, and the prevention of heart attacks, strokes and cardiovascular death
Repaglinide (Prandin)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Type 2 diabetes — a fast, short-acting tablet taken with meals
Rosuvastatin (Crestor)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
High cholesterol, and the risk of a heart attack or stroke
Stenabolic (SR9009) (Sold as Stenabolic; the compound is SR9009, with the close analogue SR9011)
Small chemical medicineLaboratory or animal-stage researchDetailed record
Use listed on the medicine record
Sold as "exercise in a pill" — never tested in a human, and it does not need its own target
Tamoxifen (Nolvadex / Soltamox)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Breast cancer that grows on oestrogen — treating it, and reducing the chance of getting it
Tapentadol (Nucynta / Nucynta ER / Palexia)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Severe pain needing an opioid, including the nerve pain of diabetes, when other options are inadequate
Tofersen (Qalsody)
Gene-silencing medicineFDA accelerated approval (based on an earlier result expected to predict benefit; follow-up evidence may be required)Detailed record
Use listed on the medicine record
SOD1 Amyotrophic Lateral Sclerosis (ALS)
Tramadol (Ultram, Ultram ER, Conzip, Qdolo, Ryzolt)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Moderate to severe pain, as an opioid
Tranexamic Acid (Cyklokapron / Lysteda)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Heavy bleeding — from injury, after childbirth, during surgery, during periods, or after a dental extraction in haemophilia
Tretinoin (topical) (Retin-A / Retin-A Micro / Renova / Atralin / Avita)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Acne, and fine facial lines from sun damage
Vitamin K2 MK-7 (Menaquinone-7; the dominant branded ingredient in the trial literature is MenaQ7)
Nutritional or plant productDietary supplement; not FDA-approved as a medicineDetailed record
Use listed on the medicine record
Taken with vitamin D for bone density and to keep calcium out of the arteries
Zileuton (Zyflo / Zyflo CR)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Long-term asthma control, for the small number of people who cannot use the alternatives
Albuterol (Ventolin HFA / ProAir HFA / Proventil HFA)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
A sudden tight chest and wheeze — the blue rescue inhaler
Alendronate (Fosamax / Binosto)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Thinning, fragile bones that break more easily than they should
Alfuzosin (Uroxatral)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
A weak or hesitant stream, going often, and getting up at night, caused by an enlarged prostate
Aminocaproic Acid (Amicar)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Bleeding that will not stop because the body is dissolving its own clots too fast
Amlodipine / Valsartan (Exforge)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
High blood pressure that one tablet has not brought down
Bimatoprost (Lumigan)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
High pressure inside the eye — and, sold under a different name, thin eyelashes

Topiramate (Topamax / Trokendi XR / Qudexy XR)

Trazodone (Desyrel / Oleptro (both discontinued as brands))

Zilebesiran (ALN-AGT01 (investigational))

Argatroban (Argatroban in 0.9% Sodium Chloride)

Aripiprazole (Abilify)

Azathioprine (Imuran / Azasan)

Beclomethasone (Qvar / Qvar Redihaler / Qnasl / Beconase AQ / Vancenase AQ / Beclovent)

Benzonatate (Tessalon)

Calcitriol (Rocaltrol / Calcijex / Vectical)

Cannabis (Plant Preparation) (Sold as flower, resin, concentrate and edible. Isolated delta-9-THC and cannabidiol have their own records on this site)

Caplacizumab (Cablivi)

Chlorpheniramine (Chlor-Trimeton / Allergy Relief)

Clopidogrel (Plavix)

Clozapine (Clozaril, FazaClo, Versacloz)

Daclatasvir (Daklinza)

Dalteparin (Fragmin)

Dextromethorphan (Sold over the counter in hundreds of cough products. Prescription combinations: Nuedexta (with quinidine, NDA 021879, 2010) and Auvelity (with bupropion, NDA 215430, 2022))

Dolutegravir (Tivicay / Tivicay PD)

Emicizumab (Hemlibra)

Eplontersen (Wainua)

Esketamine (Spravato)

Fluvastatin (Lescol / Lescol XL)

Glimepiride (Amaryl)

Glipizide (Glucotrol / Glucotrol XL)

Haloperidol (Haldol)

Hydroxyzine (Atarax / Vistaril)

Ibutamoren (MK-677, also written MK-0677; ibutamoren mesylate)

Indomethacin (Indocin, Tivorbex, Indocin IV)

Lamivudine (Epivir for HIV-1 and Epivir-HBV for hepatitis B, at different strengths; also in Combivir, Epzicom, Triumeq and Dovato)

Latanoprost (Xalatan)

Losartan (Cozaar)

Lovotibeglogene autotemcel (Lyfgenia)

Metronidazole (Flagyl / MetroGel)

Mometasone (Asmanex Twisthaler / Asmanex HFA / Nasonex / Elocon / Sinuva)

Naproxen (Naprosyn, Anaprox, Aleve, Naprelan)

Nitrous Oxide (Nitrous Oxide USP, approved as a prescription medical gas under several NDAs including NDA 205704 (2013). Entonox is the 50:50 nitrous oxide / oxygen mixture used for labour and procedural analgesia)

Nortriptyline (Pamelor / Aventyl — both discontinued as brands)

Olopatadine (Patanol / Pataday / Patanase)

Oseltamivir (Tamiflu)

Pantoprazole (Protonix / Protonix IV)

Phenibut (β-Phenyl-GABA) (Fenibut, Anvifen, Noofen — prescription products in Russia, Latvia, Ukraine and Kazakhstan. In the United States it is sold in supplements under names such as Fenibut and β-phenyl-GABA)

Phentermine (Adipex-P; also the phentermine half of Qsymia)

Pravastatin (Pravachol)

Repaglinide (Prandin)

Rosuvastatin (Crestor)

Stenabolic (SR9009) (Sold as Stenabolic; the compound is SR9009, with the close analogue SR9011)

Tamoxifen (Nolvadex / Soltamox)

Tapentadol (Nucynta / Nucynta ER / Palexia)

Tofersen (Qalsody)

Tramadol (Ultram, Ultram ER, Conzip, Qdolo, Ryzolt)

Tranexamic Acid (Cyklokapron / Lysteda)

Tretinoin (topical) (Retin-A / Retin-A Micro / Renova / Atralin / Avita)

Vitamin K2 MK-7 (Menaquinone-7; the dominant branded ingredient in the trial literature is MenaQ7)

Zileuton (Zyflo / Zyflo CR)

Albuterol (Ventolin HFA / ProAir HFA / Proventil HFA)

Alendronate (Fosamax / Binosto)

Alfuzosin (Uroxatral)

Aminocaproic Acid (Amicar)

Amlodipine / Valsartan (Exforge)

Bimatoprost (Lumigan)