Public dataset
Recorded source agreement and disagreement
Show whether sources print one normalized reading, have incompatible units, lack structured comparison context, or contain a context-matched numeric difference.
- Public rows
- 1,681
- Generated
- Schema version
- source-consensus/2
Coverage
What this run contains
- Compared medicine fields
- 1,681
- Agree
- 1,282
- Differ
- 0
- Not comparable
- 12
- Insufficient context
- 387
- Fields represented
- 5
- bioavailability, halfLife, proteinBinding, tMax, volumeOfDistribution
Method
How the rows were made
- Deterministic rules normalize recorded pharmacokinetic readings and compare only like-for-like values.
- One normalized printed reading may be agree even when clinical context was not extracted; this reports printed-reading agreement only.
- Distinct readings may differ only when their units and denominators are comparable and one matching, non-placeholder population/formulation context was structurally extracted. Otherwise they are insufficient_context.
- not_comparable preserves incompatible units or denominators instead of guessing. insufficient_context preserves missing or non-matching structured context instead of manufacturing agreement or disagreement.
- The agreement rate describes the distribution of recorded source readings; it is not a probability that a value is true.
- Every distinct printed reading retains its unit, population context, source count, and complete source records. The API paginates field rows, never child readings or sources.
- documentsExamined is every matching single-substance archive document inspected for that medicine. The generator has no document, reading, or source ceiling, so there is no hidden available-versus-retained remainder.
Limits
Read these before using a row
- Current label parsing does not structurally extract population or formulation context. Distinct otherwise-comparable readings are therefore insufficient_context, never differ; agree may mean printed-reading agreement only. Source records are complete but are not independent-experiment counts.
- The current deterministic parser does not structurally extract population or formulation context from these sentences. It records that context as unknown and cannot publish distinct same-unit readings as differ.
- Neither reading is marked wrong. Population, formulation, route, and other unextracted context may explain the printed difference.
- Only the recorded fields and source documents in this snapshot are compared.
- A source count is the number of retained source records in the row, not a count of independent experiments.
Provenance
Source examples
abacavir · bioavailability · agree
15 documents examined; 83% (Unknown: population and formulation context were not structurally extracted from this source sentence.)
FDA_LABEL:5676d391-f9a4-44be-9604-954b3d8d0e2b (opens source in a new tab)The geometric mean absolute bioavailability of the tablet was 83%.
alemtuzumab · volumeOfDistribution · not_comparable
2 documents examined; 0.18 L/kg (Unknown: population and formulation context were not structurally extracted from this source sentence.); 14.1 L (Unknown: population and formulation context were not structurally extracted from this source sentence.)
FDA_LABEL:4f5f7255-7abc-4328-bd1a-ceaf139ef3e0 (opens source in a new tab)Distribution After the last 30 mg dose, the mean volume of distribution at steady-state was 0.18 L/kg (range 0.1 to 0.4 L/kg).
abiraterone · halfLife · insufficient_context
31 documents examined; 12 ± 5 hours (Unknown: population and formulation context were not structurally extracted from this source sentence.); 18 hours (Unknown: population and formulation context were not structurally extracted from this source sentence.)
FDA_LABEL:c9eb9b46-f847-40a8-802c-a51b40406d5a (opens source in a new tab)Elimination In patients with metastatic CRPC, the mean terminal half-life of abiraterone in plasma (mean ± SD) is 12 ± 5 hours.
Artifact used for this view: data/source-consensus.ndjson. The reader resolves the current run first and uses the checked-in compatibility run only when a current artifact is absent.
Schema
Fields in the public projection
| Field | Type | Meaning |
|---|---|---|
| medicineSlug | string | Stable RNAWiki medicine route key. |
| field | string | Recorded pharmacokinetic field being compared. |
| comparisonState | string | agree (printed-reading agreement), differ (context-matched comparable disjoint values), not_comparable (unit/denominator mismatch), or insufficient_context. Every state remains declared even when its current count is zero. |
| comparisonReasons | string[] | Deterministic codes explaining the state. |
| documentsExamined | number | Recorded source documents considered for the field. |
| sourceCount | number | Recorded source readings represented. |
| agreementRate | number | Share represented by the leading normalized printed-reading group; not a confidence score or clinical agreement probability. |
| readings | consensus-reading[] | Complete, untruncated reading groups. Each keeps the printed display, numeric value when parsed, unit, population context, source count, and every source identity, version/effective date or explicit absence, retrieval date, locator, safe link, and excerpt. |
Reader
Search and filter the rows
Showing 781–790 of 1,681 matching rows. Filters and search terms remain attached when you move between pages or open the API view.
Projected row 781
- Medicine slug
- isosorbide-dinitrate
- Compared field
- bioavailability
- Comparison state
- agree
- Reason codes
- COMPATIBLE_VALUES_OVERLAP
- Documents examined
- 21
- Source count
- 21
- Agreement rate
- 1
- Recorded readings
10%
- Numeric value
- 10
- Unit
- %
- Source records
- 21
Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.
Show all 21 source records
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:33d14f59-3ae8-4414-b826-06274cf0f3d9 (opens source in a new tab)
Isosorbide Dinitrate label
Version not recorded · Effective date not recorded
Pharmacokinetics Absorption of isosorbide dinitrate after oral dosing is nearly complete, but bioavailability is highly variable (10% to 90%), with extensive first-pass metabolism in the liver.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:829ed058-333f-453c-9f0e-9202e03acf97 (opens source in a new tab)
Isosorbide Dinitrate label
Version not recorded · Effective date not recorded
Pharmacokinetics Absorption of isosorbide dinitrate after oral dosing is nearly complete, but bioavailability is highly variable (10% to 90%), with extensive first-pass metabolism in the liver.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:f1d52e9a-8de1-61db-e053-2a95a90aae50 (opens source in a new tab)
Isosorbide Dinitrate label
Version not recorded · Effective date not recorded
Pharmacokinetics Absorption of isosorbide dinitrate after oral dosing is nearly complete, but bioavailability is highly variable (10% to 90%), with extensive first-pass metabolism in the liver.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:5c94ecc0-fcaa-4af3-82c2-ff124f2df3e1 (opens source in a new tab)
Isosorbide Dinitrate label
Version not recorded · Effective date not recorded
Pharmacokinetics Absorption of isosorbide dinitrate after oral dosing is nearly complete, but bioavailability is highly variable (10% to 90%), with extensive first-pass metabolism in the liver.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:74a7f767-fa2f-4640-be24-34a8a9128217 (opens source in a new tab)
Isosorbide Dinitrate label
Version not recorded · Effective date not recorded
Pharmacokinetics Absorption of isosorbide dinitrate after oral dosing is nearly complete, but bioavailability is highly variable (10% to 90%), with extensive first-pass metabolism in the liver.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:7f860fbd-f130-4652-e053-2991aa0a402e (opens source in a new tab)
Isosorbide Dinitrate label
Version not recorded · Effective date not recorded
Pharmacokinetics Absorption of isosorbide dinitrate after oral dosing is nearly complete, but bioavailability is highly variable (10% to 90%), with extensive first-pass metabolism in the liver.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:0e5842f2-74f6-1f02-01bc-07578bd3b393 (opens source in a new tab)
Isosorbide Dinitrate label
Version not recorded · Effective date not recorded
Pharmacokinetics Absorption of isosorbide dinitrate after oral dosing is nearly complete, but bioavailability is highly variable (10% to 90%), with extensive first-pass metabolism in the liver.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:6c4997e7-9ce6-46a6-a9c1-4bd3d76155eb (opens source in a new tab)
Isosorbide Dinitrate label
Version not recorded · Effective date not recorded
Pharmacokinetics Absorption of isosorbide dinitrate after oral dosing is nearly complete, but bioavailability is highly variable (10% to 90%), with extensive first-pass metabolism in the liver.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:5f585259-59ed-4648-b562-164f3746c821 (opens source in a new tab)
Isosorbide Dinitrate label
Version not recorded · Effective date not recorded
Pharmacokinetics Absorption of isosorbide dinitrate after oral dosing is nearly complete, but bioavailability is highly variable (10% to 90%), with extensive first-pass metabolism in the liver.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:1cf9b6dd-9d4e-4ea1-95ae-e9e46a3d1b20 (opens source in a new tab)
Isosorbide Dinitrate label
Version not recorded · Effective date not recorded
Pharmacokinetics Absorption of isosorbide dinitrate after oral dosing is nearly complete, but bioavailability is highly variable (10% to 90%), with extensive first-pass metabolism in the liver.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:9498fa14-1614-4a8e-b872-41c11745b01e (opens source in a new tab)
Isosorbide Dinitrate label
Version not recorded · Effective date not recorded
Pharmacokinetics Absorption of isosorbide dinitrate after oral dosing is nearly complete, but bioavailability is highly variable (10% to 90%), with extensive first-pass metabolism in the liver.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:5b0db8af-bcf9-458f-b752-420130cba428 (opens source in a new tab)
Isosorbide Dinitrate label
Version not recorded · Effective date not recorded
Pharmacokinetics Absorption of isosorbide dinitrate after oral dosing is nearly complete, but bioavailability is highly variable (10% to 90%), with extensive first-pass metabolism in the liver.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:f0b9b320-0bf8-4342-b654-135ccb6755c2 (opens source in a new tab)
Isosorbide Dinitrate label
Version not recorded · Effective date not recorded
Pharmacokinetics Absorption of isosorbide dinitrate after oral dosing is nearly complete, but bioavailability is highly variable (10% to 90%), with extensive first-pass metabolism in the liver.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:b166eb5b-bad8-4663-9c05-1c43539dab2c (opens source in a new tab)
Isosorbide Dinitrate label
Version not recorded · Effective date not recorded
Pharmacokinetics Absorption of isosorbide dinitrate after oral dosing is nearly complete, but bioavailability is highly variable (10% to 90%), with extensive first-pass metabolism in the liver.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:73a1e6c0-71d0-4ba1-bbca-c067479e487d (opens source in a new tab)
Isosorbide Dinitrate label
Version not recorded · Effective date not recorded
Pharmacokinetics Absorption of isosorbide dinitrate after oral dosing is nearly complete, but bioavailability is highly variable (10% to 90%), with extensive first-pass metabolism in the liver.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:246c749d-aa28-44ce-8d42-984660afff2a (opens source in a new tab)
Isosorbide Dinitrate label
Version not recorded · Effective date not recorded
Pharmacokinetics Absorption of isosorbide dinitrate after oral dosing is nearly complete, but bioavailability is highly variable (10% to 90%), with extensive first-pass metabolism in the liver.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:3d6164d7-3083-41c5-a6a6-7e144fe29f7d (opens source in a new tab)
Isosorbide Dinitrate label
Version not recorded · Effective date not recorded
Pharmacokinetics Absorption of isosorbide dinitrate after oral dosing is nearly complete, but bioavailability is highly variable (10% to 90%), with extensive first-pass metabolism in the liver.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:71fdd147-a987-40b6-9f07-82d56525ceb8 (opens source in a new tab)
Isosorbide Dinitrate label
Version not recorded · Effective date not recorded
Pharmacokinetics Absorption of isosorbide dinitrate after oral dosing is nearly complete, but bioavailability is highly variable (10% to 90%), with extensive first-pass metabolism in the liver.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:723d9f78-9d77-4575-af27-1aa117e6b8d7 (opens source in a new tab)
Isosorbide Dinitrate label
Version not recorded · Effective date not recorded
Pharmacokinetics Absorption of isosorbide dinitrate after oral dosing is nearly complete, but bioavailability is highly variable (10% to 90%), with extensive first-pass metabolism in the liver.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:16818b32-ee5e-4e07-b848-31e892c4b98a (opens source in a new tab)
Isosorbide Dinitrate label
Version not recorded · Effective date not recorded
Pharmacokinetics Absorption of isosorbide dinitrate after oral dosing is nearly complete, but bioavailability is highly variable (10% to 90%), with extensive first-pass metabolism in the liver.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:6df6a2fa-c56c-4eb6-a485-c16585420eb0 (opens source in a new tab)
Isosorbide Dinitrate label
Version not recorded · Effective date not recorded
Pharmacokinetics Absorption of isosorbide dinitrate after oral dosing is nearly complete, but bioavailability is highly variable (10% to 90%), with extensive first-pass metabolism in the liver.
Projected row 782
- Medicine slug
- isosorbide-dinitrate
- Compared field
- halfLife
- Comparison state
- agree
- Reason codes
- COMPATIBLE_VALUES_OVERLAP
- Documents examined
- 21
- Source count
- 21
- Agreement rate
- 1
- Recorded readings
5 hours
- Numeric value
- 5
- Unit
- hours
- Source records
- 21
Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.
Show all 21 source records
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:33d14f59-3ae8-4414-b826-06274cf0f3d9 (opens source in a new tab)
Isosorbide Dinitrate label
Version not recorded · Effective date not recorded
With an overall half-life of about 5 hours, the 5-mononitrate is cleared from the serum by denitration to isosorbide, glucuronidation to the 5-mononitrate glucuronide, and denitration/hydration to sorbitol.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:829ed058-333f-453c-9f0e-9202e03acf97 (opens source in a new tab)
Isosorbide Dinitrate label
Version not recorded · Effective date not recorded
With an overall half-life of about 5 hours, the 5-mononitrate is cleared from the serum by denitration to isosorbide, glucuronidation to the 5-mononitrate glucuronide, and denitration/hydration to sorbitol.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:f1d52e9a-8de1-61db-e053-2a95a90aae50 (opens source in a new tab)
Isosorbide Dinitrate label
Version not recorded · Effective date not recorded
With an overall half-life of about 5 hours, the 5-mononitrate is cleared from the serum by denitration to isosorbide, glucuronidation to the 5-mononitrate glucuronide, and denitration/hydration to sorbitol.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:5c94ecc0-fcaa-4af3-82c2-ff124f2df3e1 (opens source in a new tab)
Isosorbide Dinitrate label
Version not recorded · Effective date not recorded
With an overall half-life of about 5 hours, the 5-mononitrate is cleared from the serum by denitration to isosorbide, glucuronidation to the 5-mononitrate glucuronide, and denitration/hydration to sorbitol.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:74a7f767-fa2f-4640-be24-34a8a9128217 (opens source in a new tab)
Isosorbide Dinitrate label
Version not recorded · Effective date not recorded
With an overall half-life of about 5 hours, the 5-mononitrate is cleared from the serum by denitration to isosorbide, glucuronidation to the 5-mononitrate glucuronide, and denitration/hydration to sorbitol.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:7f860fbd-f130-4652-e053-2991aa0a402e (opens source in a new tab)
Isosorbide Dinitrate label
Version not recorded · Effective date not recorded
With an overall half-life of about 5 hours, the 5-mononitrate is cleared from the serum by denitration to isosorbide, glucuronidation to the 5-mononitrate glucuronide, and denitration/hydration to sorbitol.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:0e5842f2-74f6-1f02-01bc-07578bd3b393 (opens source in a new tab)
Isosorbide Dinitrate label
Version not recorded · Effective date not recorded
With an overall half-life of about 5 hours, the 5-mononitrate is cleared from the serum by denitration to isosorbide, glucuronidation to the 5-mononitrate glucuronide, and denitration/hydration to sorbitol.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:6c4997e7-9ce6-46a6-a9c1-4bd3d76155eb (opens source in a new tab)
Isosorbide Dinitrate label
Version not recorded · Effective date not recorded
With an overall half-life of about 5 hours, the 5-mononitrate is cleared from the serum by denitration to isosorbide, glucuronidation to the 5-mononitrate glucuronide, and denitration/hydration to sorbitol.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:5f585259-59ed-4648-b562-164f3746c821 (opens source in a new tab)
Isosorbide Dinitrate label
Version not recorded · Effective date not recorded
With an overall half-life of about 5 hours, the 5-mononitrate is cleared from the serum by denitration to isosorbide, glucuronidation to the 5-mononitrate glucuronide, and denitration/hydration to sorbitol.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:1cf9b6dd-9d4e-4ea1-95ae-e9e46a3d1b20 (opens source in a new tab)
Isosorbide Dinitrate label
Version not recorded · Effective date not recorded
With an overall half-life of about 5 hours, the 5-mononitrate is cleared from the serum by denitration to isosorbide, glucuronidation to the 5-mononitrate glucuronide, and denitration/hydration to sorbitol.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:9498fa14-1614-4a8e-b872-41c11745b01e (opens source in a new tab)
Isosorbide Dinitrate label
Version not recorded · Effective date not recorded
With an overall half-life of about 5 hours, the 5-mononitrate is cleared from the serum by denitration to isosorbide, glucuronidation to the 5-mononitrate glucuronide, and denitration/hydration to sorbitol.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:5b0db8af-bcf9-458f-b752-420130cba428 (opens source in a new tab)
Isosorbide Dinitrate label
Version not recorded · Effective date not recorded
With an overall half-life of about 5 hours, the 5-mononitrate is cleared from the serum by denitration to isosorbide, glucuronidation to the 5-mononitrate glucuronide, and denitration/hydration to sorbitol.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:f0b9b320-0bf8-4342-b654-135ccb6755c2 (opens source in a new tab)
Isosorbide Dinitrate label
Version not recorded · Effective date not recorded
With an overall half-life of about 5 hours, the 5-mononitrate is cleared from the serum by denitration to isosorbide, glucuronidation to the 5-mononitrate glucuronide, and denitration/hydration to sorbitol.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:b166eb5b-bad8-4663-9c05-1c43539dab2c (opens source in a new tab)
Isosorbide Dinitrate label
Version not recorded · Effective date not recorded
With an overall half-life of about 5 hours, the 5-mononitrate is cleared from the serum by denitration to isosorbide, glucuronidation to the 5-mononitrate glucuronide, and denitration/hydration to sorbitol.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:73a1e6c0-71d0-4ba1-bbca-c067479e487d (opens source in a new tab)
Isosorbide Dinitrate label
Version not recorded · Effective date not recorded
With an overall half-life of about 5 hours, the 5-mononitrate is cleared from the serum by denitration to isosorbide, glucuronidation to the 5-mononitrate glucuronide, and denitration/hydration to sorbitol.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:246c749d-aa28-44ce-8d42-984660afff2a (opens source in a new tab)
Isosorbide Dinitrate label
Version not recorded · Effective date not recorded
With an overall half-life of about 5 hours, the 5-mononitrate is cleared from the serum by denitration to isosorbide, glucuronidation to the 5-mononitrate glucuronide, and denitration/hydration to sorbitol.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:3d6164d7-3083-41c5-a6a6-7e144fe29f7d (opens source in a new tab)
Isosorbide Dinitrate label
Version not recorded · Effective date not recorded
With an overall half-life of about 5 hours, the 5-mononitrate is cleared from the serum by denitration to isosorbide, glucuronidation to the 5-mononitrate glucuronide, and denitration/hydration to sorbitol.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:71fdd147-a987-40b6-9f07-82d56525ceb8 (opens source in a new tab)
Isosorbide Dinitrate label
Version not recorded · Effective date not recorded
With an overall half-life of about 5 hours, the 5-mononitrate is cleared from the serum by denitration to isosorbide, glucuronidation to the 5-mononitrate glucuronide, and denitration/hydration to sorbitol.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:723d9f78-9d77-4575-af27-1aa117e6b8d7 (opens source in a new tab)
Isosorbide Dinitrate label
Version not recorded · Effective date not recorded
With an overall half-life of about 5 hours, the 5-mononitrate is cleared from the serum by denitration to isosorbide, glucuronidation to the 5-mononitrate glucuronide, and denitration/hydration to sorbitol.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:16818b32-ee5e-4e07-b848-31e892c4b98a (opens source in a new tab)
Isosorbide Dinitrate label
Version not recorded · Effective date not recorded
With an overall half-life of about 5 hours, the 5-mononitrate is cleared from the serum by denitration to isosorbide, glucuronidation to the 5-mononitrate glucuronide, and denitration/hydration to sorbitol.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:6df6a2fa-c56c-4eb6-a485-c16585420eb0 (opens source in a new tab)
Isosorbide Dinitrate label
Version not recorded · Effective date not recorded
With an overall half-life of about 5 hours, the 5-mononitrate is cleared from the serum by denitration to isosorbide, glucuronidation to the 5-mononitrate glucuronide, and denitration/hydration to sorbitol.
Projected row 783
- Medicine slug
- isosorbide-dinitrate
- Compared field
- volumeOfDistribution
- Comparison state
- insufficient_context
- Reason codes
- STRUCTURED_CONTEXT_MISSING
- Documents examined
- 21
- Source count
- 21
- Agreement rate
- 0.761905
- Recorded readings
2 to 4 L/kg
- Numeric value
- 2
- Unit
- L/kg
- Source records
- 16
Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.
Show all 16 source records
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:33d14f59-3ae8-4414-b826-06274cf0f3d9 (opens source in a new tab)
Isosorbide Dinitrate label
Version not recorded · Effective date not recorded
Once absorbed, the volume of distribution of isosorbide dinitrate is 2 to 4 L/kg, and this volume is cleared at the rate of 2 to 4 L/min, so ISDN's half-life in serum is about an hour.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:829ed058-333f-453c-9f0e-9202e03acf97 (opens source in a new tab)
Isosorbide Dinitrate label
Version not recorded · Effective date not recorded
Once absorbed, the volume of distribution of isosorbide dinitrate is 2 to 4 L/kg, and this volume is cleared at the rate of 2 to 4 L/min, so ISDN's half-life in serum is about an hour.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:5c94ecc0-fcaa-4af3-82c2-ff124f2df3e1 (opens source in a new tab)
Isosorbide Dinitrate label
Version not recorded · Effective date not recorded
Once absorbed, the volume of distribution of isosorbide dinitrate is 2 to 4 L/kg, and this volume is cleared at the rate of 2 to 4 L/min, so isosorbide dinitrate's half-life in serum is about an hour.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:74a7f767-fa2f-4640-be24-34a8a9128217 (opens source in a new tab)
Isosorbide Dinitrate label
Version not recorded · Effective date not recorded
Once absorbed, the volume of distribution of isosorbide dinitrate is 2 to 4 L/kg, and this volume is cleared at the rate of 2 to 4 L/min, so ISDN's half-life in serum is about an hour.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:7f860fbd-f130-4652-e053-2991aa0a402e (opens source in a new tab)
Isosorbide Dinitrate label
Version not recorded · Effective date not recorded
Once absorbed, the volume of distribution of isosorbide dinitrate is 2 to 4 L/kg, and this volume is cleared at the rate of 2 to 4 L/min, so ISDN’s half-life in serum is about an hour.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:0e5842f2-74f6-1f02-01bc-07578bd3b393 (opens source in a new tab)
Isosorbide Dinitrate label
Version not recorded · Effective date not recorded
Once absorbed, the volume of distribution of isosorbide dinitrate is 2 to 4 L/kg, and this volume is cleared at the rate of 2 to 4 L/min, so isosorbide dinitrate's half-life in serum is about an hour.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:6c4997e7-9ce6-46a6-a9c1-4bd3d76155eb (opens source in a new tab)
Isosorbide Dinitrate label
Version not recorded · Effective date not recorded
Once absorbed, the volume of distribution of isosorbide dinitrate is 2 to 4 L/kg, and this volume is cleared at the rate of 2 to 4 L/min, so ISDN’s half-life in serum is about an hour.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:5f585259-59ed-4648-b562-164f3746c821 (opens source in a new tab)
Isosorbide Dinitrate label
Version not recorded · Effective date not recorded
Once absorbed, the volume of distribution of isosorbide dinitrate is 2 to 4 L/kg, and this volume is cleared at the rate of 2 to 4 L/min, so ISDN’s half-life in serum is about an hour.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:1cf9b6dd-9d4e-4ea1-95ae-e9e46a3d1b20 (opens source in a new tab)
Isosorbide Dinitrate label
Version not recorded · Effective date not recorded
Once absorbed, the volume of distribution of isosorbide dinitrate is 2 to 4 L/kg, and this volume is cleared at the rate of 2 to 4 L/min, so ISDN's half-life in serum is about an hour.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:9498fa14-1614-4a8e-b872-41c11745b01e (opens source in a new tab)
Isosorbide Dinitrate label
Version not recorded · Effective date not recorded
Once absorbed, the volume of distribution of isosorbide dinitrate is 2 to 4 L/kg, and this volume is cleared at the rate of 2 to 4 L/min, so ISDN's half-life in serum is about an hour.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:f0b9b320-0bf8-4342-b654-135ccb6755c2 (opens source in a new tab)
Isosorbide Dinitrate label
Version not recorded · Effective date not recorded
Once absorbed, the volume of distribution of isosorbide dinitrate is 2 to 4 L/kg, and this volume is cleared at the rate of 2 to 4 L/min, so ISDN’s half-life in serum is about an hour.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:b166eb5b-bad8-4663-9c05-1c43539dab2c (opens source in a new tab)
Isosorbide Dinitrate label
Version not recorded · Effective date not recorded
Once absorbed, the volume of distribution of isosorbide dinitrate is 2 to 4 L/kg, and this volume is cleared at the rate of 2 to 4 L/min, so ISDN's half-life in serum is about an hour.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:73a1e6c0-71d0-4ba1-bbca-c067479e487d (opens source in a new tab)
Isosorbide Dinitrate label
Version not recorded · Effective date not recorded
Once absorbed, the volume of distribution of isosorbide dinitrate is 2 to 4 L/kg, and this volume is cleared at the rate of 2 to 4 L/min, so isosorbide dinitrate’s half-life in serum is about an hour.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:3d6164d7-3083-41c5-a6a6-7e144fe29f7d (opens source in a new tab)
Isosorbide Dinitrate label
Version not recorded · Effective date not recorded
Once absorbed, the volume of distribution of isosorbide dinitrate is 2 to 4 L/kg, and this volume is cleared at the rate of 2 to 4 L/min, so isosorbide dinitrate’s half-life in serum is about an hour.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:723d9f78-9d77-4575-af27-1aa117e6b8d7 (opens source in a new tab)
Isosorbide Dinitrate label
Version not recorded · Effective date not recorded
Once absorbed, the volume of distribution of isosorbide dinitrate is 2 to 4 L/kg, and this volume is cleared at the rate of 2 to 4 L/min, so ISDN's half-life in serum is about an hour.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:6df6a2fa-c56c-4eb6-a485-c16585420eb0 (opens source in a new tab)
Isosorbide Dinitrate label
Version not recorded · Effective date not recorded
Once absorbed, the volume of distribution of isosorbide dinitrate is 2 to 4 L/kg, and this volume is cleared at the rate of 2 to 4 L/min, so isosorbide dinitrate's half-life in serum is about an hour.
2 L/kg
- Numeric value
- 2
- Unit
- L/kg
- Source records
- 5
Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.
Show all 5 source records
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:f1d52e9a-8de1-61db-e053-2a95a90aae50 (opens source in a new tab)
Isosorbide Dinitrate label
Version not recorded · Effective date not recorded
Once absorbed, the volume of distribution of isosorbide dinitrate is 2 L/kg to 4 L/kg, and this volume is cleared at the rate of 2 L/min to 4 L/min, so ISDN's half-life in serum is about an hour.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:5b0db8af-bcf9-458f-b752-420130cba428 (opens source in a new tab)
Isosorbide Dinitrate label
Version not recorded · Effective date not recorded
Once absorbed, the volume of distribution of isosorbide dinitrate is 2 L/kg to 4 L/kg, and this volume is cleared at the rate of 2 L/min to 4 L/min, so ISDN's half-life in serum is about an hour.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:246c749d-aa28-44ce-8d42-984660afff2a (opens source in a new tab)
Isosorbide Dinitrate label
Version not recorded · Effective date not recorded
Once absorbed, the volume of distribution of isosorbide dinitrate is 2 L/kg to 4 L/kg, and this volume is cleared at the rate of 2 L/min to 4 L/min, so ISDN's half-life in serum is about an hour.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:71fdd147-a987-40b6-9f07-82d56525ceb8 (opens source in a new tab)
Isosorbide Dinitrate label
Version not recorded · Effective date not recorded
Once absorbed, the volume of distribution of isosorbide dinitrate is 2 L/kg to 4 L/kg, and this volume is cleared at the rate of 2 L/min to 4 L/min, so ISDN’s half-life in serum is about an hour.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:16818b32-ee5e-4e07-b848-31e892c4b98a (opens source in a new tab)
Isosorbide Dinitrate label
Version not recorded · Effective date not recorded
Once absorbed, the volume of distribution of isosorbide dinitrate is 2 L/kg to 4 L/kg, and this volume is cleared at the rate of 2 L/min to 4 L/min, so ISDN's half-life in serum is about an hour.
Projected row 784
- Medicine slug
- isosorbide-mononitrate
- Compared field
- bioavailability
- Comparison state
- agree
- Reason codes
- COMPATIBLE_VALUES_OVERLAP
- Documents examined
- 38
- Source count
- 29
- Agreement rate
- 1
- Recorded readings
100%
- Numeric value
- 100
- Unit
- %
- Source records
- 29
Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.
Show all 29 source records
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:7443a5b6-6153-4227-870c-3c710f1f2174 (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
Pharmacokinetics and Metabolism After oral administration of ISMN as a solution or immediate-release tablets, maximum plasma concentrations of ISMN are achieved in 30 to 60 minutes, with an absolute bioavailability of approximately 100%.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:8cbb364a-bafe-454b-a53f-bd7cd69a5593 (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
Pharmacokinetics and Metabolism After oral administration of ISMN as a solution or immediate-release tablets, maximum plasma concentrations of ISMN are achieved in 30 to 60 minutes, with an absolute bioavailability of approximately 100%.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:86be0e85-5337-bee4-e053-2a91aa0a8158 (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
Pharmacokinetics and Metabolism After oral administration of ISMN as a solution or immediate-release tablets, maximum plasma concentrations of ISMN are achieved in 30 to 60 minutes, with an absolute bioavailability of approximately 100%.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:55810c9d-1140-40b8-a297-210a84afc05a (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
Pharmacokinetics and Metabolism After oral administration of ISMN as a solution or immediate-release tablets, maximum plasma concentrations of ISMN are achieved in 30 to 60 minutes, with an absolute bioavailability of approximately 100%.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:d01d4f0f-5164-4ea3-b772-72b97961c6fb (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
Pharmacokinetics and Metabolism After oral administration of ISMN as a solution or immediate-release tablets, maximum plasma concentrations of ISMN are achieved in 30 to 60 minutes, with an absolute bioavailability of approximately 100%.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:c950760f-0e32-483f-96f2-eecaf057c0ec (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
Pharmacokinetics and Metabolism After oral administration of ISMN as a solution or immediate-release tablets, maximum plasma concentrations of ISMN are achieved in 30 to 60 minutes, with an absolute bioavailability of approximately 100%.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:5fd86c08-18de-43a2-9962-ab6cbf57d6c0 (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
Pharmacokinetics and Metabolism After oral administration of ISMN as a solution or immediate-release tablets, maximum plasma concentrations of ISMN are achieved in 30 to 60 minutes, with an absolute bioavailability of approximately 100%.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:18cf36bc-e73f-4274-b381-c2f2aa02f57d (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
Pharmacokinetics and Metabolism After oral administration of ISMN as a solution or immediate-release tablets, maximum plasma concentrations of ISMN are achieved in 30 to 60 minutes, with an absolute bioavailability of approximately 100%.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:44a0f691-b826-4580-ab2d-b5d1cc99e283 (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
Pharmacokinetics and Metabolism After oral administration of ISMN as a solution or immediate-release tablets, maximum plasma concentrations of ISMN are achieved in 30 to 60 minutes, with an absolute bioavailability of approximately 100%.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:5a8164a3-56e2-4b9b-8718-0423b4b4958f (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
Pharmacokinetics and Metabolism After oral administration of ISMN as a solution or immediate-release tablets, maximum plasma concentrations of ISMN are achieved in 30 to 60 minutes, with an absolute bioavailability of approximately 100%.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:adcca9b8-0505-4bbc-81ab-05efc7407b6b (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
Pharmacokinetics and Metabolism After oral administration of ISMN as a solution or immediate-release tablets, maximum plasma concentrations of ISMN are achieved in 30 to 60 minutes, with an absolute bioavailability of approximately 100%.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:cd953cfa-b6f5-4b82-afcc-52a57236b9d3 (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
Pharmacokinetics and Metabolism After oral administration of ISMN as a solution or immediate-release tablets, maximum plasma concentrations of ISMN are achieved in 30 to 60 minutes, with an absolute bioavailability of approximately 100%.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:0e3c4461-2e04-481f-a9e5-29f21cc71ec5 (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
Pharmacokinetics and Metabolism After oral administration of ISMN as a solution or immediate-release tablets, maximum plasma concentrations of ISMN are achieved in 30 to 60 minutes, with an absolute bioavailability of approximately 100%.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:cd60ded0-01d9-4a51-a8ad-cdfeb27d88fb (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
Pharmacokinetics and Metabolism After oral administration of ISMN as a solution or immediate-release tablets, maximum plasma concentrations of ISMN are achieved in 30 to 60 minutes, with an absolute bioavailability of approximately 100%.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:df5fd5e2-3a7b-5a5b-e053-2995a90a0dd3 (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
Pharmacokinetics and Metabolism After oral administration of ISMN as a solution or immediate-release tablets, maximum plasma concentrations of ISMN are achieved in 30 to 60 minutes, with an absolute bioavailability of approximately 100%.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:72b8a20c-5833-4765-a4b5-9066eaec6ea1 (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
Pharmacokinetics and Metabolism After oral administration of ISMN as a solution or immediate-release tablets, maximum plasma concentrations of ISMN are achieved in 30 to 60 minutes, with an absolute bioavailability of approximately 100%.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:46b3030d-f492-da9d-e063-6294a90a31b3 (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
Pharmacokinetics and Metabolism After oral administration of ISMN as a solution or immediate-release tablets, maximum plasma concentrations of ISMN are achieved in 30 to 60 minutes, with an absolute bioavailability of approximately 100%.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:96420729-2bc7-4d03-9c51-f786ea678998 (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
Pharmacokinetics and Metabolism After oral administration of ISMN as a solution or immediate-release tablets, maximum plasma concentrations of ISMN are achieved in 30 to 60 minutes, with an absolute bioavailability of approximately 100%.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:63dc518f-4f86-4820-98c2-5de8aed09a4b (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
Pharmacokinetics and Metabolism After oral administration of ISMN as a solution or immediate-release tablets, maximum plasma concentrations of ISMN are achieved in 30 to 60 minutes, with an absolute bioavailability of approximately 100%.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:b38f43c8-d02d-4aee-ab23-e898cbfadfbc (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
Pharmacokinetics and Metabolism After oral administration of ISMN as a solution or immediate-release tablets, maximum plasma concentrations of ISMN are achieved in 30 to 60 minutes, with an absolute bioavailability of approximately 100%.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:ba6120c8-c885-4cfa-b68e-9eee7a3bad6d (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
Pharmacokinetics and Metabolism After oral administration of ISMN as a solution or immediate-release tablets, maximum plasma concentrations of ISMN are achieved in 30 to 60 minutes, with an absolute bioavailability of approximately 100%.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:4da5a0ac-574d-48ea-80ba-55344bfefb91 (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
Pharmacokinetics and Metabolism After oral administration of ISMN as a solution or immediate-release tablets, maximum plasma concentrations of ISMN are achieved in 30 to 60 minutes, with an absolute bioavailability of approximately 100%.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:0af6c67f-919d-4515-8074-f6c3aaa835b5 (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
Pharmacokinetics and Metabolism After oral administration of ISMN as a solution or immediate-release tablets, maximum plasma concentrations of ISMN are achieved in 30 to 60 minutes, with an absolute bioavailability of approximately 100%.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:17525ff2-9ec0-15a1-e063-6394a90ab762 (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
Pharmacokinetics and Metabolism After oral administration of ISMN as a solution or immediate-release tablets, maximum plasma concentrations of ISMN are achieved in 30 to 60 minutes, with an absolute bioavailability of approximately 100%.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:2d99893a-296a-134c-e063-6294a90ace3b (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
Pharmacokinetics and Metabolism After oral administration of ISMN as a solution or immediate-release tablets, maximum plasma concentrations of ISMN are achieved in 30 to 60 minutes, with an absolute bioavailability of approximately 100%.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:6a582db5-eb45-4320-98c1-55517d7d8c38 (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
Pharmacokinetics and Metabolism After oral administration of ISMN as a solution or immediate-release tablets, maximum plasma concentrations of ISMN are achieved in 30 to 60 minutes, with an absolute bioavailability of approximately 100%.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:441ddd35-6cb8-44d0-8009-1635390ede83 (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
Pharmacokinetics and Metabolism After oral administration of ISMN as a solution or immediate-release tablets, maximum plasma concentrations of ISMN are achieved in 30 to 60 minutes, with an absolute bioavailability of approximately 100%.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:65935a15-a023-1941-e053-2991aa0a5eb4 (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
Pharmacokinetics and Metabolism: After oral administration of ISMN as a solution or immediate-release tablets, maximum plasma concentrations of ISMN are achieved in 30 to 60 minutes, with an absolute bioavailability of approximately 100%.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:0a1e317a-7b05-4d30-9bbc-1d4ccd56ba3c (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
Pharmacokinetics and Metabolism After oral administration of ISMN as a solution or immediate-release tablets, maximum plasma concentrations of ISMN are achieved in 30 to 60 minutes, with an absolute bioavailability of approximately 100%.
Projected row 785
- Medicine slug
- isosorbide-mononitrate
- Compared field
- halfLife
- Comparison state
- agree
- Reason codes
- COMPATIBLE_VALUES_OVERLAP
- Documents examined
- 38
- Source count
- 38
- Agreement rate
- 1
- Recorded readings
5 hours
- Numeric value
- 5
- Unit
- hours
- Source records
- 38
Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.
Show all 38 source records
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:7443a5b6-6153-4227-870c-3c710f1f2174 (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
The mean plasma elimination half-life of ISMN is approximately 5 hours.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:8cbb364a-bafe-454b-a53f-bd7cd69a5593 (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
The mean plasma elimination half-life of ISMN is approximately 5 hours.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:86be0e85-5337-bee4-e053-2a91aa0a8158 (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
The mean plasma elimination half-life of ISMN is approximately 5 hours.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:55810c9d-1140-40b8-a297-210a84afc05a (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
The mean plasma elimination half-life of ISMN is approximately 5 hours.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:d01d4f0f-5164-4ea3-b772-72b97961c6fb (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
The mean plasma elimination half-life of ISMN is approximately 5 hours.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:c950760f-0e32-483f-96f2-eecaf057c0ec (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
The mean plasma elimination half-life of ISMN is approximately 5 hours.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:5fd86c08-18de-43a2-9962-ab6cbf57d6c0 (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
The mean plasma elimination half-life of ISMN is approximately 5 hours.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:18cf36bc-e73f-4274-b381-c2f2aa02f57d (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
The mean plasma elimination half-life of ISMN is approximately 5 hours.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:44a0f691-b826-4580-ab2d-b5d1cc99e283 (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
The mean plasma elimination half-life of ISMN is approximately 5 hours.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:5a8164a3-56e2-4b9b-8718-0423b4b4958f (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
The mean plasma elimination half-life of ISMN is approximately 5 hours.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:adcca9b8-0505-4bbc-81ab-05efc7407b6b (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
The mean plasma elimination half-life of ISMN is approximately 5 hours.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:cd953cfa-b6f5-4b82-afcc-52a57236b9d3 (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
The mean plasma elimination half-life of ISMN is approximately 5 hours.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:0e3c4461-2e04-481f-a9e5-29f21cc71ec5 (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
The mean plasma elimination half-life of ISMN is approximately 5 hours.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:f871dfa7-219f-4704-8e4d-215caeb7408d (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
The overall elimination half-life of isosorbide mononitrate is about 5 hours.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:cdf01e14-778b-4b3f-8372-1c18f266fb98 (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
The overall elimination half-life of isosorbide mononitrate is about 5 hours.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:cd60ded0-01d9-4a51-a8ad-cdfeb27d88fb (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
The mean plasma elimination half-life of ISMN is approximately 5 hours.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:3dffc84e-93e4-0005-e063-6294a90aa9ca (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
The overall elimination half-life of isosorbide mononitrate is about 5 hours.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:06839534-85b8-42aa-b0e3-079ed236be44 (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
The overall elimination half-life of isosorbide mononitrate is about 5 hours.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:55f240e1-3056-38cc-e063-6294a90a814e (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
The overall elimination half-life of isosorbide mononitrate is about 5 hours.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:bf9e7e35-7707-42a0-88d6-6292fa52bbfa (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
The overall elimination half-life of isosorbide mononitrate is about 5 hours.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:df5fd5e2-3a7b-5a5b-e053-2995a90a0dd3 (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
The mean plasma elimination half-life of ISMN is approximately 5 hours.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:72b8a20c-5833-4765-a4b5-9066eaec6ea1 (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
The mean plasma elimination half-life of ISMN is approximately 5 hours.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:46b3030d-f492-da9d-e063-6294a90a31b3 (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
The mean plasma elimination half-life of ISMN is approximately 5 hours.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:96420729-2bc7-4d03-9c51-f786ea678998 (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
The mean plasma elimination half-life of ISMN is approximately 5 hours.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:63dc518f-4f86-4820-98c2-5de8aed09a4b (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
The mean plasma elimination half-life of ISMN is approximately 5 hours.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:3e0e013f-6887-fa72-e063-6294a90a18ca (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
The overall elimination half-life of isosorbide mononitrate is about 5 hours.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:b38f43c8-d02d-4aee-ab23-e898cbfadfbc (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
The mean plasma elimination half-life of ISMN is approximately 5 hours.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:ba6120c8-c885-4cfa-b68e-9eee7a3bad6d (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
The mean plasma elimination half-life of ISMN is approximately 5 hours.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:4da5a0ac-574d-48ea-80ba-55344bfefb91 (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
The mean plasma elimination half-life of ISMN is approximately 5 hours.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:0af6c67f-919d-4515-8074-f6c3aaa835b5 (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
The mean plasma elimination half-life of ISMN is approximately 5 hours.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:17525ff2-9ec0-15a1-e063-6394a90ab762 (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
The mean plasma elimination half-life of ISMN is approximately 5 hours.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:ae8f74f0-e600-4452-8557-958b603e2709 (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
The overall elimination half-life of isosorbide mononitrate is about 5 hours.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:2d99893a-296a-134c-e063-6294a90ace3b (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
The mean plasma elimination half-life of ISMN is approximately 5 hours.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:6a582db5-eb45-4320-98c1-55517d7d8c38 (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
The mean plasma elimination half-life of ISMN is approximately 5 hours.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:441ddd35-6cb8-44d0-8009-1635390ede83 (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
The mean plasma elimination half-life of ISMN is approximately 5 hours.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:0d739bf3-0672-4504-9064-b39d6b200b47 (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
The overall elimination half-life of isosorbide mononitrate is about 5 hours.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:65935a15-a023-1941-e053-2991aa0a5eb4 (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
The mean plasma elimination half-life of ISMN is approximately 5 hours.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:0a1e317a-7b05-4d30-9bbc-1d4ccd56ba3c (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
The mean plasma elimination half-life of ISMN is approximately 5 hours.
Projected row 786
- Medicine slug
- isosorbide-mononitrate
- Compared field
- proteinBinding
- Comparison state
- agree
- Reason codes
- COMPATIBLE_VALUES_OVERLAP
- Documents examined
- 38
- Source count
- 9
- Agreement rate
- 1
- Recorded readings
5%
- Numeric value
- 5
- Unit
- %
- Source records
- 9
Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.
Show all 9 source records
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:f871dfa7-219f-4704-8e4d-215caeb7408d (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
Plasma protein binding of isosorbide mononitrate was found to be less than 5%.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:cdf01e14-778b-4b3f-8372-1c18f266fb98 (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
Plasma protein binding of isosorbide mononitrate was found to be less than 5%.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:3dffc84e-93e4-0005-e063-6294a90aa9ca (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
Plasma protein binding of isosorbide mononitrate was found to be less than 5%.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:06839534-85b8-42aa-b0e3-079ed236be44 (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
Plasma protein binding of isosorbide mononitrate was found to be less than 5%.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:55f240e1-3056-38cc-e063-6294a90a814e (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
Plasma protein binding of isosorbide mononitrate was found to be less than 5%.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:bf9e7e35-7707-42a0-88d6-6292fa52bbfa (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
Plasma protein binding of isosorbide mononitrate was found to be less than 5%.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:3e0e013f-6887-fa72-e063-6294a90a18ca (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
Plasma protein binding of isosorbide mononitrate was found to be less than 5%.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:ae8f74f0-e600-4452-8557-958b603e2709 (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
Plasma protein binding of isosorbide mononitrate was found to be less than 5%.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:0d739bf3-0672-4504-9064-b39d6b200b47 (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
Plasma protein binding of isosorbide mononitrate was found to be less than 5%.
Projected row 787
- Medicine slug
- isosorbide-mononitrate
- Compared field
- volumeOfDistribution
- Comparison state
- insufficient_context
- Reason codes
- STRUCTURED_CONTEXT_MISSING
- Documents examined
- 38
- Source count
- 38
- Agreement rate
- 0.763158
- Recorded readings
0.6 to 0.7 L/kg
- Numeric value
- 0.6
- Unit
- L/kg
- Source records
- 29
Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.
Show all 29 source records
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:7443a5b6-6153-4227-870c-3c710f1f2174 (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
After intravenous administration, ISMN is distributed into total body water in about 9 minutes with a volume of distribution of approximately 0.6 to 0.7 L/kg.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:8cbb364a-bafe-454b-a53f-bd7cd69a5593 (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
After intravenous administration, ISMN is distributed into total body water in about 9 minutes with a volume of distribution of approximately 0.6-0.7 L/kg.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:86be0e85-5337-bee4-e053-2a91aa0a8158 (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
After intravenous administration, ISMN is distributed into total body water in about 9 minutes with a volume of distribution of approximately 0.6 to 0.7 L/kg.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:55810c9d-1140-40b8-a297-210a84afc05a (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
After intravenous administration, ISMN is distributed into total body water in about 9 minutes with a volume of distribution of approximately 0.6 to 0.7 L/kg.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:d01d4f0f-5164-4ea3-b772-72b97961c6fb (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
After intravenous administration, ISMN is distributed into total body water in about 9 minutes with a volume of distribution of approximately 0.6-0.7 L/kg.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:c950760f-0e32-483f-96f2-eecaf057c0ec (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
After intravenous administration, ISMN is distributed into total body water in about 9 minutes with a volume of distribution of approximately 0.6 to 0.7 L/kg.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:5fd86c08-18de-43a2-9962-ab6cbf57d6c0 (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
After intravenous administration, ISMN is distributed into total body water in about 9 minutes with a volume of distribution of approximately 0.6 to 0.7 L/kg.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:18cf36bc-e73f-4274-b381-c2f2aa02f57d (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
After intravenous administration, ISMN is distributed into total body water in about 9 minutes with a volume of distribution of approximately 0.6 to 0.7 L/kg.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:44a0f691-b826-4580-ab2d-b5d1cc99e283 (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
After intravenous administration, ISMN is distributed into total body water in about 9 minutes with a volume of distribution of approximately 0.6 to 0.7 L/kg.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:5a8164a3-56e2-4b9b-8718-0423b4b4958f (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
After intravenous administration, ISMN is distributed into total body water in about 9 minutes with a volume of distribution of approximately 0.6 to 0.7 L/kg.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:adcca9b8-0505-4bbc-81ab-05efc7407b6b (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
After intravenous administration, ISMN is distributed into total body water in about 9 minutes with a volume of distribution of approximately 0.6 to 0.7 L/kg.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:cd953cfa-b6f5-4b82-afcc-52a57236b9d3 (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
After intravenous administration, ISMN is distributed into total body water in about 9 minutes with a volume of distribution of approximately 0.6-0.7 L/kg.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:0e3c4461-2e04-481f-a9e5-29f21cc71ec5 (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
After intravenous administration, ISMN is distributed into total body water in about 9 minutes with a volume of distribution of approximately 0.6 to 0.7 L/kg.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:cd60ded0-01d9-4a51-a8ad-cdfeb27d88fb (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
After intravenous administration, ISMN is distributed into total body water in about 9 minutes with a volume of distribution of approximately 0.6-0.7 L/kg.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:df5fd5e2-3a7b-5a5b-e053-2995a90a0dd3 (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
After intravenous administration, ISMN is distributed into total body water in about 9 minutes with a volume of distribution of approximately 0.6 to 0.7 L/kg.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:72b8a20c-5833-4765-a4b5-9066eaec6ea1 (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
After intravenous administration, ISMN is distributed into total body water in about 9 minutes with a volume of distribution of approximately 0.6-0.7 L/kg.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:46b3030d-f492-da9d-e063-6294a90a31b3 (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
After intravenous administration, ISMN is distributed into total body water in about 9 minutes with a volume of distribution of approximately 0.6 to 0.7 L/kg.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:96420729-2bc7-4d03-9c51-f786ea678998 (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
After intravenous administration, ISMN is distributed into total body water in about 9 minutes with a volume of distribution of approximately 0.6 to 0.7 L/kg.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:63dc518f-4f86-4820-98c2-5de8aed09a4b (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
After intravenous administration, ISMN is distributed into total body water in about 9 minutes with a volume of distribution of approximately 0.6-0.7 L/kg.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:b38f43c8-d02d-4aee-ab23-e898cbfadfbc (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
After intravenous administration, ISMN is distributed into total body water in about 9 minutes with a volume of distribution of approximately 0.6-0.7 L/kg.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:ba6120c8-c885-4cfa-b68e-9eee7a3bad6d (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
After intravenous administration, ISMN is distributed into total body water in about 9 minutes with a volume of distribution of approximately 0.6-0.7 L/kg.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:4da5a0ac-574d-48ea-80ba-55344bfefb91 (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
After intravenous administration, ISMN is distributed into total body water in about 9 minutes with a volume of distribution of approximately 0.6 to 0.7 L/kg.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:0af6c67f-919d-4515-8074-f6c3aaa835b5 (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
After intravenous administration, ISMN is distributed into total body water in about 9 minutes with a volume of distribution of approximately 0.6 to 0.7 L/kg.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:17525ff2-9ec0-15a1-e063-6394a90ab762 (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
After intravenous administration, ISMN is distributed into total body water in about 9 minutes with a volume of distribution of approximately 0.6 to 0.7 L/kg.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:2d99893a-296a-134c-e063-6294a90ace3b (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
After intravenous administration, ISMN is distributed into total body water in about 9 minutes with a volume of distribution of approximately 0.6 to 0.7 L/kg.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:6a582db5-eb45-4320-98c1-55517d7d8c38 (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
After intravenous administration, ISMN is distributed into total body water in about 9 minutes with a volume of distribution of approximately 0.6-0.7 L/kg.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:441ddd35-6cb8-44d0-8009-1635390ede83 (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
After intravenous administration, ISMN is distributed into total body water in about 9 minutes with a volume of distribution of approximately 0.6 to 0.7 L/kg.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:65935a15-a023-1941-e053-2991aa0a5eb4 (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
After intravenous administration, ISMN is distributed into total body water in about 9 minutes with a volume of distribution of approximately 0.6 to 0.7 L/kg.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:0a1e317a-7b05-4d30-9bbc-1d4ccd56ba3c (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
After intravenous administration, ISMN is distributed into total body water in about 9 minutes with a volume of distribution of approximately 0.6-0.7 L/kg.
0.6 L/kg
- Numeric value
- 0.6
- Unit
- L/kg
- Source records
- 9
Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.
Show all 9 source records
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:f871dfa7-219f-4704-8e4d-215caeb7408d (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
The volume of distribution is approximately 0.6 L/kg.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:cdf01e14-778b-4b3f-8372-1c18f266fb98 (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
The volume of distribution is approximately 0.6 L/kg.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:3dffc84e-93e4-0005-e063-6294a90aa9ca (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
The volume of distribution is approximately 0.6 L/kg.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:06839534-85b8-42aa-b0e3-079ed236be44 (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
The volume of distribution is approximately 0.6 L/kg.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:55f240e1-3056-38cc-e063-6294a90a814e (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
The volume of distribution is approximately 0.6 L/kg.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:bf9e7e35-7707-42a0-88d6-6292fa52bbfa (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
The volume of distribution is approximately 0.6 L/kg.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:3e0e013f-6887-fa72-e063-6294a90a18ca (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
The volume of distribution is approximately 0.6 L/kg.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:ae8f74f0-e600-4452-8557-958b603e2709 (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
The volume of distribution is approximately 0.6 L/kg.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:0d739bf3-0672-4504-9064-b39d6b200b47 (opens source in a new tab)
Isosorbide Mononitrate label
Version not recorded · Effective date not recorded
The volume of distribution is approximately 0.6 L/kg.
Projected row 788
- Medicine slug
- isotretinoin
- Compared field
- halfLife
- Comparison state
- insufficient_context
- Reason codes
- STRUCTURED_CONTEXT_MISSING
- Documents examined
- 19
- Source count
- 9
- Agreement rate
- 0.555556
- Recorded readings
90 hours
- Numeric value
- 90
- Unit
- hours
- Source records
- 5
Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.
Show all 5 source records
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:27b3cf26-f22e-5b70-1c24-009933b7c6ee (opens source in a new tab)
Isotretinoin label
Version not recorded · Effective date not recorded
Elimination Following oral administration of an 80 mg dose of 14 C-isotretinoin as a liquid suspension, 14 C-activity in blood declined with a half-life of 90 hours.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:c369e1c3-90c5-4768-9741-56c62253a2c4 (opens source in a new tab)
Isotretinoin label
Version not recorded · Effective date not recorded
Elimination Following oral administration of an 80 mg dose of 14 C-isotretinoin as a liquid suspension, 14 C-activity in blood declined with a half-life of 90 hours.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:486d4a4b-0de5-431a-bef7-dae6b0e4fa20 (opens source in a new tab)
Isotretinoin label
Version not recorded · Effective date not recorded
Elimination Following oral administration of an 80 mg dose of 14 C-isotretinoin as a liquid suspension, 14 C-activity in blood declined with a half-life of 90 hours.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:5b524a51-a16b-496e-b764-11c98c479c36 (opens source in a new tab)
Isotretinoin label
Version not recorded · Effective date not recorded
Elimination Following oral administration of an 80 mg dose of 14 C-isotretinoin as a liquid suspension, 14 C-activity in blood declined with a half-life of 90 hours.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:0114567b-3bac-490d-b9eb-03a6c5d90935 (opens source in a new tab)
Isotretinoin label
Version not recorded · Effective date not recorded
Elimination Following oral administration of an 80 mg dose of 14 C-isotretinoin as a liquid suspension, 14 C-activity in blood declined with a half-life of 90 hours.
21± 8.2 hours
- Numeric value
- 21
- Unit
- hours
- Source records
- 4
Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.
Show all 4 source records
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:b2cb63c9-f825-4991-9a2c-6260f1bbcc2c (opens source in a new tab)
Isotretinoin label
Version not recorded · Effective date not recorded
Elimination The mean ± SD elimination half-life of isotretinoin is 21± 8.2 hours and 24 ± 5.3 hours for its 4-oxo-isotretinoin metabolite.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:c2917c3d-3499-48a0-ba53-120cb979195d (opens source in a new tab)
Isotretinoin label
Version not recorded · Effective date not recorded
Elimination The mean ± SD elimination half-life of isotretinoin is 21± 8.2 hours and 24 ± 5.3 hours for its 4-oxo-isotretinoin metabolite.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:28948c32-a598-4bb5-bdb5-efbd87214d98 (opens source in a new tab)
Isotretinoin label
Version not recorded · Effective date not recorded
Elimination The mean ± SD elimination half-life of isotretinoin is 21± 8.2 hours and 24 ± 5.3 hours for its 4-oxo-isotretinoin metabolite.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:a31fd109-d0fd-4ab9-ba98-a3d64333c18d (opens source in a new tab)
Isotretinoin label
Version not recorded · Effective date not recorded
Elimination The mean ± SD elimination half-life of isotretinoin is 21 ± 8.2 hours and 24 ± 5.3 hours for its 4-oxo-isotretinoin metabolite.
Projected row 789
- Medicine slug
- isotretinoin
- Compared field
- tMax
- Comparison state
- insufficient_context
- Reason codes
- STRUCTURED_CONTEXT_MISSING
- Documents examined
- 19
- Source count
- 14
- Agreement rate
- 0.714286
- Recorded readings
6.4 hours
- Numeric value
- 6.4
- Unit
- hours
- Source records
- 10
Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.
Show all 10 source records
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:ebe1b3e3-1013-4cf6-bdc8-2baa3dc26e16 (opens source in a new tab)
Isotretinoin label
Version not recorded · Effective date not recorded
Absorption Following Isotretinoin Administration The isotretinoin mean T max was 6.4 hours under fed conditions and 2.9 hours under fasting conditions following administration of a single 40 mg dose.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:b44200ba-6672-4ea7-b151-7caec3f53c9c (opens source in a new tab)
Isotretinoin label
Version not recorded · Effective date not recorded
Absorption Following Isotretinoin Capsules Administration The isotretinoin capsules mean T max was 6.4 hours under fed conditions and 2.9 hours under fasting conditions following administration of a single 40 mg dose.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:9f1c8971-c6dc-4708-848b-5cee50b6c32a (opens source in a new tab)
Isotretinoin label
Version not recorded · Effective date not recorded
Absorption Following Isotretinoin Administration The isotretinoin mean T max was 6.4 hours under fed conditions and 2.9 hours under fasting conditions following administration of a single 40 mg dose.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:4e8516dc-a3c6-4d8f-aa14-2c37c6c8f6e6 (opens source in a new tab)
Isotretinoin label
Version not recorded · Effective date not recorded
Absorption Following Isotretinoin Administration The isotretinoin mean T max was 6.4 hours under fed conditions and 2.9 hours under fasting conditions following administration of a single 40 mg dose.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:08529687-26b2-41e5-b6fb-35b4c0d891fe (opens source in a new tab)
Isotretinoin label
Version not recorded · Effective date not recorded
Absorption Following Isotretinoin Administration The isotretinoin mean T max was 6.4 hours under fed conditions and 2.9 hours under fasting conditions following administration of a single 40 mg dose.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:3ef0cff8-19c1-4441-b780-fca6c7ee1615 (opens source in a new tab)
Isotretinoin label
Version not recorded · Effective date not recorded
Absorption Following ABSORICA Administration The ABSORICA mean T max was 6.4 hours under fed conditions and 2.9 hours under fasting conditions following administration of a single 40 mg dose.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:ff1edbb8-ac0e-4563-9c2a-94385ce055e3 (opens source in a new tab)
Isotretinoin label
Version not recorded · Effective date not recorded
Absorption Following Isotretinoin Administration The isotretinoin mean T max was 6.4 hours under fed conditions and 2.9 hours under fasting conditions following administration of a single 40 mg dose.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:31f62a49-4c6d-4ce3-a0ca-d159562370b1 (opens source in a new tab)
Isotretinoin label
Version not recorded · Effective date not recorded
Absorption Following Isotretinoin Administration The isotretinoin mean Tmax was 6.4 hours under fed conditions and 2.9 hours under fasting conditions following administration of a single 40 mg dose.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:1cf11710-f966-4529-8e08-02175f588bca (opens source in a new tab)
Isotretinoin label
Version not recorded · Effective date not recorded
Absorption Following Isotretinoin Administration The isotretinoin mean T max was 6.4 hours under fed conditions and 2.9 hours under fasting conditions following administration of a single 40 mg dose.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:72867c88-070f-4608-bfef-cc5225ebce6d (opens source in a new tab)
Isotretinoin label
Version not recorded · Effective date not recorded
Absorption Following Isotretinoin Administration The isotretinoin mean T max was 6.4 hours under fed conditions and 2.9 hours under fasting conditions following administration of a single 40 mg dose.
5.3 hours
- Numeric value
- 5.3
- Unit
- hours
- Source records
- 4
Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.
Show all 4 source records
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:b2cb63c9-f825-4991-9a2c-6260f1bbcc2c (opens source in a new tab)
Isotretinoin label
Version not recorded · Effective date not recorded
Absorption Isotretinoin time to maximum concentration (T max ) is 5.3 hours (77%) when administered with food.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:c2917c3d-3499-48a0-ba53-120cb979195d (opens source in a new tab)
Isotretinoin label
Version not recorded · Effective date not recorded
Absorption Isotretinoin time to maximum concentration (T max ) is 5.3 hours (77%) when administered with food.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:28948c32-a598-4bb5-bdb5-efbd87214d98 (opens source in a new tab)
Isotretinoin label
Version not recorded · Effective date not recorded
Absorption Isotretinoin time to maximum concentration (T max ) is 5.3 hours (77%) when administered with food.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:a31fd109-d0fd-4ab9-ba98-a3d64333c18d (opens source in a new tab)
Isotretinoin label
Version not recorded · Effective date not recorded
Absorption Isotretinoin time to maximum concentration (T max ) is 5.3 hours (77%) when administered with food.
Projected row 790
- Medicine slug
- isradipine
- Compared field
- bioavailability
- Comparison state
- agree
- Reason codes
- COMPATIBLE_VALUES_OVERLAP
- Documents examined
- 3
- Source count
- 3
- Agreement rate
- 1
- Recorded readings
15%
- Numeric value
- 15
- Unit
- %
- Source records
- 3
Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.
Show all 3 source records
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:bf3425e0-428d-4bdb-ac9a-3b9d483df83a (opens source in a new tab)
Isradipine label
Version not recorded · Effective date not recorded
Pharmacokinetics and Metabolism Isradipine is 90% to 95% absorbed and is subject to extensive first-pass metabolism, resulting in a bioavailability of about 15% to 24%.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:acf7c376-6cb6-4857-b455-0bf5da29346c (opens source in a new tab)
Isradipine label
Version not recorded · Effective date not recorded
Pharmacokinetics and Metabolism Isradipine is 90% to 95% absorbed and is subject to extensive first-pass metabolism, resulting in a bioavailability of about 15% to 24%.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:fdb4c50e-6e6f-a43d-e053-6294a90aa24f (opens source in a new tab)
Isradipine label
Version not recorded · Effective date not recorded
Pharmacokinetics and Metabolism Isradipine is 90%-95% absorbed and is subject to extensive first-pass metabolism, resulting in a bioavailability of about 15%-24%.
Access
Query or download the projection
GET /api/datasets/source-consensus?limit=10&offset=780Allowed query parameters
- q
- Case-insensitive text search over the public fields named for this dataset.
- state
- Exact comparability state.Values: agree, differ, not_comparable, insufficient_context
- field
- Exact recorded field key.Values: bioavailability, halfLife, proteinBinding, tMax, volumeOfDistribution
- limit / offset
- Pagination is required. limit is at most 200; offset is bounded. Set format=csv for the same projected page as a download.
Reuse and corrections
Keep the boundary attached
CC BY 4.0 applies to RNAWiki licenses its selection, schema, structure, and derived projection. Quoted source passages and third-party records retain their original rights.
Cite RNAWiki, this dataset identifier, and the generated date. Keep the “does not mean” statement with any downstream display so a corpus measurement is not mistaken for medical advice.