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Public dataset

Recorded source agreement and disagreement

Show whether sources print one normalized reading, have incompatible units, lack structured comparison context, or contain a context-matched numeric difference.

What this does not mean: agree can mean only that sources print the same normalized reading; it is not clinical-context equivalence, independent replication, or proof. differ requires matching structured context and disjoint comparable values. not_comparable and insufficient_context are not disagreement.
Public rows
1,681
Generated
Schema version
source-consensus/2

Coverage

What this run contains

Compared medicine fields
1,681
Agree
1,282
Differ
0
Not comparable
12
Insufficient context
387
Fields represented
5
bioavailability, halfLife, proteinBinding, tMax, volumeOfDistribution

Method

How the rows were made

  1. Deterministic rules normalize recorded pharmacokinetic readings and compare only like-for-like values.
  2. One normalized printed reading may be agree even when clinical context was not extracted; this reports printed-reading agreement only.
  3. Distinct readings may differ only when their units and denominators are comparable and one matching, non-placeholder population/formulation context was structurally extracted. Otherwise they are insufficient_context.
  4. not_comparable preserves incompatible units or denominators instead of guessing. insufficient_context preserves missing or non-matching structured context instead of manufacturing agreement or disagreement.
  5. The agreement rate describes the distribution of recorded source readings; it is not a probability that a value is true.
  6. Every distinct printed reading retains its unit, population context, source count, and complete source records. The API paginates field rows, never child readings or sources.
  7. documentsExamined is every matching single-substance archive document inspected for that medicine. The generator has no document, reading, or source ceiling, so there is no hidden available-versus-retained remainder.

Limits

Read these before using a row

  • Current label parsing does not structurally extract population or formulation context. Distinct otherwise-comparable readings are therefore insufficient_context, never differ; agree may mean printed-reading agreement only. Source records are complete but are not independent-experiment counts.
  • The current deterministic parser does not structurally extract population or formulation context from these sentences. It records that context as unknown and cannot publish distinct same-unit readings as differ.
  • Neither reading is marked wrong. Population, formulation, route, and other unextracted context may explain the printed difference.
  • Only the recorded fields and source documents in this snapshot are compared.
  • A source count is the number of retained source records in the row, not a count of independent experiments.

Provenance

Source examples

abacavir · bioavailability · agree

15 documents examined; 83% (Unknown: population and formulation context were not structurally extracted from this source sentence.)

FDA_LABEL:5676d391-f9a4-44be-9604-954b3d8d0e2b (opens source in a new tab)
The geometric mean absolute bioavailability of the tablet was 83%.

alemtuzumab · volumeOfDistribution · not_comparable

2 documents examined; 0.18 L/kg (Unknown: population and formulation context were not structurally extracted from this source sentence.); 14.1 L (Unknown: population and formulation context were not structurally extracted from this source sentence.)

FDA_LABEL:4f5f7255-7abc-4328-bd1a-ceaf139ef3e0 (opens source in a new tab)
Distribution After the last 30 mg dose, the mean volume of distribution at steady-state was 0.18 L/kg (range 0.1 to 0.4 L/kg).

abiraterone · halfLife · insufficient_context

31 documents examined; 12 ± 5 hours (Unknown: population and formulation context were not structurally extracted from this source sentence.); 18 hours (Unknown: population and formulation context were not structurally extracted from this source sentence.)

FDA_LABEL:c9eb9b46-f847-40a8-802c-a51b40406d5a (opens source in a new tab)
Elimination In patients with metastatic CRPC, the mean terminal half-life of abiraterone in plasma (mean ± SD) is 12 ± 5 hours.

Artifact used for this view: data/source-consensus.ndjson. The reader resolves the current run first and uses the checked-in compatibility run only when a current artifact is absent.

Schema

Fields in the public projection

FieldTypeMeaning
medicineSlugstringStable RNAWiki medicine route key.
fieldstringRecorded pharmacokinetic field being compared.
comparisonStatestringagree (printed-reading agreement), differ (context-matched comparable disjoint values), not_comparable (unit/denominator mismatch), or insufficient_context. Every state remains declared even when its current count is zero.
comparisonReasonsstring[]Deterministic codes explaining the state.
documentsExaminednumberRecorded source documents considered for the field.
sourceCountnumberRecorded source readings represented.
agreementRatenumberShare represented by the leading normalized printed-reading group; not a confidence score or clinical agreement probability.
readingsconsensus-reading[]Complete, untruncated reading groups. Each keeps the printed display, numeric value when parsed, unit, population context, source count, and every source identity, version/effective date or explicit absence, retrieval date, locator, safe link, and excerpt.

Reader

Search and filter the rows

Case-insensitive text search over the public fields named for this dataset.

Exact comparability state.

Exact recorded field key.

Clear

Showing 771780 of 1,681 matching rows. Filters and search terms remain attached when you move between pages or open the API view.

  1. Projected row 771

    Medicine slug
    ioversol
    Compared field
    volumeOfDistribution
    Comparison state
    agree
    Reason codes
    • COMPATIBLE_VALUES_OVERLAP
    Documents examined
    3
    Source count
    3
    Agreement rate
    1
    Recorded readings
    1. 0.26 L/kg

      Numeric value
      0.26
      Unit
      L/kg
      Source records
      3

      Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.

      Show all 3 source records
      1. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:549d38db-d4ed-4708-8f76-7cdaa157063f (opens source in a new tab)

        Ioversol label

        Version not recorded · Effective date not recorded

        The volume of distribution in adults was 0.26 L/kg body weight, consistent with distribution to the extracellular space.
      2. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:6cb6ca5f-b249-49b0-a9eb-8aa583da7c74 (opens source in a new tab)

        Ioversol label

        Version not recorded · Effective date not recorded

        The volume of distribution in adults was 0.26 L/kg body weight, consistent with distribution to the extracellular space.
      3. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:cd718d1c-f813-4114-a50d-c744ff7eb1bf (opens source in a new tab)

        Ioversol label

        Version not recorded · Effective date not recorded

        The volume of distribution in adults was 0.26 L/kg body weight, consistent with distribution to the extracellular space.
  2. Projected row 772

    Medicine slug
    irbesartan
    Compared field
    bioavailability
    Comparison state
    agree
    Reason codes
    • COMPATIBLE_VALUES_OVERLAP
    Documents examined
    45
    Source count
    45
    Agreement rate
    1
    Recorded readings
    1. 60%

      Numeric value
      60
      Unit
      %
      Source records
      45

      Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.

      Show all 45 source records
      1. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:1ab1ff46-d0b1-4762-9ebf-3e07dde8b048 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        There was no effect on serum uric acid during chronic oral administration, and no uricosuric effect. 12.3 Pharmacokinetics Absorption The oral absorption of irbesartan is rapid and complete with an average absolute bioavailability of 60% to 80%.
      2. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:868bd0a7-38ff-4722-8063-a697af3be527 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics Absorption The oral absorption of irbesartan is rapid and complete with an average absolute bioavailability of 60% to 80%.
      3. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:a7c093c2-3eef-4956-8a14-c36aada0304f (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics Absorption The oral absorption of irbesartan is rapid and complete with an average absolute bioavailability of 60% to 80%.
      4. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:ddca7d7c-07fe-4df6-83ae-a9c05048b66e (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics Absorption The oral absorption of irbesartan is rapid and complete with an average absolute bioavailability of 60% to 80%.
      5. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:6eb0cb56-2e51-45ef-9fd5-5646cf9f78a3 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        There was no effect on serum uric acid during chronic oral administration, and no uricosuric effect. 12.3 Pharmacokinetics Absorption The oral absorption of irbesartan is rapid and complete with an average absolute bioavailability of 60% to 80%.
      6. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:f0ec2ccc-7d79-4cde-a13e-08faeea4e934 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics Absorption The oral absorption of irbesartan is rapid and complete with an average absolute bioavailability of 60% to 80%.
      7. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:9644fa38-dd28-4888-9d55-80967c4fc8d7 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics Absorption The oral absorption of irbesartan is rapid and complete with an average absolute bioavailability of 60% to 80%.
      8. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:08c85ada-de6f-4cff-bc81-2332a22bef45 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics Absorption The oral absorption of irbesartan is rapid and complete with an average absolute bioavailability of 60% to 80%.
      9. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:0f3408b4-44be-4a92-a59f-9b5a9716bc9a (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics Absorption The oral absorption of irbesartan is rapid and complete with an average absolute bioavailability of 60% to 80%.
      10. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:ecc490ea-a68e-4261-8be2-5020ac5ab803 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        There was no effect on serum uric acid during chronic oral administration, and no uricosuric effect. 12.3 Pharmacokinetics Absorption The oral absorption of irbesartan is rapid and complete with an average absolute bioavailability of 60% to 80%.
      11. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:bfdf76ae-fedf-630c-e053-2995a90a9868 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        There was no effect on serum uric acid during chronic oral administration, and no uricosuric effect. 12.3 Pharmacokinetics Absorption The oral absorption of irbesartan is rapid and complete with an average absolute bioavailability of 60% to 80%.
      12. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:2113a901-2612-4557-b86d-3afc006fb8bb (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics Absorption The oral absorption of irbesartan is rapid and complete with an average absolute bioavailability of 60% to 80%.
      13. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:33416f1e-adee-4a45-b6fe-1fc39044e307 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics Absorption The oral absorption of irbesartan is rapid and complete with an average absolute bioavailability of 60% to 80%.
      14. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:6916c617-92d2-44f5-b968-6267517a2ce6 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        There was no effect on serum uric acid during chronic oral administration, and no uricosuric effect. 12.3 Pharmacokinetics Absorption The oral absorption of irbesartan is rapid and complete with an average absolute bioavailability of 60% to 80%.
      15. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:61ab1b6e-c849-49ca-a3f0-150774db649d (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        There was no effect on serum uric acid during chronic oral administration, and no uricosuric effect. 12.3 Pharmacokinetics Absorption The oral absorption of irbesartan is rapid and complete with an average absolute bioavailability of 60% to 80%.
      16. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:2d80abcb-c995-82bc-e063-6294a90aa530 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        There was no effect on serum uric acid during chronic oral administration, and no uricosuric effect. 12.3 Pharmacokinetics Absorption The oral absorption of irbesartan is rapid and complete with an average absolute bioavailability of 60% to 80%.
      17. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:950e33da-5e77-40df-b73b-dd084b36a804 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics Absorption The oral absorption of irbesartan is rapid and complete with an average absolute bioavailability of 60% to 80%.
      18. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:b587d89b-8ff9-4180-b31a-bbff5d365a1d (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        There was no effect on serum uric acid during chronic oral administration, and no uricosuric effect. 12.3 Pharmacokinetics Absorption The oral absorption of irbesartan is rapid and complete with an average absolute bioavailability of 60% to 80%.
      19. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:029a90b6-0722-49be-8400-3ec29526aafd (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        There was no effect on serum uric acid during chronic oral administration, and no uricosuric effect. 12.3 Pharmacokinetics Absorption The oral absorption of irbesartan is rapid and complete with an average absolute bioavailability of 60% to 80%.
      20. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:5b259fdd-ca4c-49c9-a50d-86066f5b0746 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics Absorption The oral absorption of irbesartan is rapid and complete with an average absolute bioavailability of 60% to 80%.
      21. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:efcd5f2e-1837-44ae-bc91-410c4d8b27c7 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        There was no effect on serum uric acid during chronic oral administration, and no uricosuric effect. 12.3 Pharmacokinetics Absorption The oral absorption of irbesartan is rapid and complete with an average absolute bioavailability of 60% to 80%.
      22. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:14d85774-2d74-4300-b4bb-c2836db4d5bd (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        There was no effect on serum uric acid during chronic oral administration, and no uricosuric effect. 12.3 Pharmacokinetics Absorption The oral absorption of irbesartan is rapid and complete with an average absolute bioavailability of 60% to 80%.
      23. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:44b72da1-4434-461f-8e3c-264ad46f85df (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics Absorption The oral absorption of irbesartan is rapid and complete with an average absolute bioavailability of 60% to 80%.
      24. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:8c9bb449-6341-4f24-9d38-6ca952e07122 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics Absorption The oral absorption of irbesartan is rapid and complete with an average absolute bioavailability of 60% to 80%.
      25. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:197871da-e0c5-49a9-8dd0-34a8c2685c6b (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics Absorption The oral absorption of irbesartan is rapid and complete with an average absolute bioavailability of 60% to 80%.
      26. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:21dd9a41-93c7-470c-94ed-f4c24e3d5633 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics Absorption The oral absorption of irbesartan is rapid and complete with an average absolute bioavailability of 60% to 80%.
      27. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:7885b2a8-be4e-48ab-8113-4e6ab791eb98 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics Absorption The oral absorption of irbesartan is rapid and complete with an average absolute bioavailability of 60% to 80%.
      28. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:fdf196d5-e933-49de-9c4c-bde50149c7d4 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics Absorption The oral absorption of irbesartan is rapid and complete with an average absolute bioavailability of 60% to 80%.
      29. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:83f5d5c8-27c0-4208-a291-0c4aa55a1ff5 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics Absorption The oral absorption of irbesartan is rapid and complete with an average absolute bioavailability of 60% to 80%.
      30. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:0898f423-0aa9-409c-8d4e-1349b59141d1 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics Absorption The oral absorption of irbesartan is rapid and complete with an average absolute bioavailability of 60% to 80%.
      31. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:e8635a1c-ae06-4e23-99f7-e704f91d6f43 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics Absorption The oral absorption of irbesartan is rapid and complete with an average absolute bioavailability of 60% to 80%.
      32. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:5c125c2a-a709-4cf1-b2d5-6e1d24a77377 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics Absorption The oral absorption of irbesartan is rapid and complete with an average absolute bioavailability of 60% to 80%.
      33. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:61b60f94-35e6-b90b-08ce-fbb2fe011f34 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        Drug Interactions (See PRECAUTIONS : Drug Interactions .) Pharmacokinetics Absorption The oral absorption of irbesartan is rapid and complete with an average absolute bioavailability of 60% to 80%.
      34. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:1f98fd95-e564-45b3-947f-45eba77f2af5 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics Absorption The oral absorption of irbesartan is rapid and complete with an average absolute bioavailability of 60% to 80%.
      35. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:7e0ddb7b-80c5-47ab-afee-c74bb735e829 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics Absorption The oral absorption of irbesartan is rapid and complete with an average absolute bioavailability of 60% to 80%.
      36. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:0c1fc197-c2d9-453c-b79f-b53de89c188b (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics Absorption The oral absorption of irbesartan is rapid and complete with an average absolute bioavailability of 60% to 80%.
      37. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:70a25c6d-23ce-488c-9ef8-62b3b99e5052 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        There was no effect on serum uric acid during chronic oral administration, and no uricosuric effect. 12.3 Pharmacokinetics Absorption The oral absorption of irbesartan is rapid and complete with an average absolute bioavailability of 60% to 80%.
      38. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:bc07bbf5-b1c6-4854-b6af-e06520c20728 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics Absorption The oral absorption of irbesartan is rapid and complete with an average absolute bioavailability of 60% to 80%.
      39. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:068224c4-a34d-32d7-bb2a-7eed44ccf7d3 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        There was no effect on serum uric acid during chronic oral administration, and no uricosuric effect. 12.3 Pharmacokinetics Absorption The oral absorption of irbesartan is rapid and complete with an average absolute bioavailability of 60% to 80%.
      40. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:9adacfa2-2814-4deb-9e34-c3b3c8dcd41a (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        There was no effect on serum uric acid during chronic oral administration, and no uricosuric effect. 12.3 Pharmacokinetics Absorption The oral absorption of irbesartan is rapid and complete with an average absolute bioavailability of 60% to 80%.
      41. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:6babdb48-8384-49ce-a759-d380d79a4010 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        There was no effect on serum uric acid during chronic oral administration, and no uricosuric effect. 12.3 Pharmacokinetics Absorption The oral absorption of irbesartan is rapid and complete with an average absolute bioavailability of 60% to 80%.
      42. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:ada35ec2-8472-411a-8e7c-ff1a0df94ab5 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics Absorption The oral absorption of irbesartan is rapid and complete with an average absolute bioavailability of 60% to 80%.
      43. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:ed789dc1-0b39-4efc-990d-7b6b43a8b3ba (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics Absorption The oral absorption of irbesartan is rapid and complete with an average absolute bioavailability of 60% to 80%.
      44. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:bb58acb0-2dc0-45ee-86bb-b405b1b75cff (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics Absorption The oral absorption of irbesartan is rapid and complete with an average absolute bioavailability of 60% to 80%.
      45. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:9b8581c1-d052-4fe2-a9fc-cf7adf0f9061 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics Absorption The oral absorption of irbesartan is rapid and complete with an average absolute bioavailability of 60% to 80%.
  3. Projected row 773

    Medicine slug
    irbesartan
    Compared field
    halfLife
    Comparison state
    insufficient_context
    Reason codes
    • STRUCTURED_CONTEXT_MISSING
    Documents examined
    45
    Source count
    45
    Agreement rate
    0.977778
    Recorded readings
    1. 11 to 15 hours

      Numeric value
      11
      Unit
      hours
      Source records
      44

      Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.

      Show all 44 source records
      1. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:1ab1ff46-d0b1-4762-9ebf-3e07dde8b048 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The terminal elimination half-life of irbesartan averages 11 to 15 hours.
      2. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:868bd0a7-38ff-4722-8063-a697af3be527 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The terminal elimination half-life of irbesartan averages 11 to 15 hours.
      3. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:a7c093c2-3eef-4956-8a14-c36aada0304f (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The terminal elimination half-life of irbesartan averages 11 to 15 hours.
      4. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:6eb0cb56-2e51-45ef-9fd5-5646cf9f78a3 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The terminal elimination half-life of irbesartan averages 11 to 15 hours.
      5. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:f0ec2ccc-7d79-4cde-a13e-08faeea4e934 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The terminal elimination half-life of irbesartan averages 11 to 15 hours.
      6. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:9644fa38-dd28-4888-9d55-80967c4fc8d7 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The terminal elimination half-life of irbesartan averages 11 to 15 hours.
      7. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:08c85ada-de6f-4cff-bc81-2332a22bef45 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The terminal elimination half-life of irbesartan averages 11 to 15 hours.
      8. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:0f3408b4-44be-4a92-a59f-9b5a9716bc9a (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The terminal elimination half-life of irbesartan averages 11 to 15 hours.
      9. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:ecc490ea-a68e-4261-8be2-5020ac5ab803 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The terminal elimination half-life of irbesartan averages 11 to 15 hours.
      10. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:bfdf76ae-fedf-630c-e053-2995a90a9868 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The terminal elimination half-life of irbesartan averages 11 to 15 hours.
      11. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:2113a901-2612-4557-b86d-3afc006fb8bb (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The terminal elimination half-life of irbesartan averages 11 to 15 hours.
      12. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:33416f1e-adee-4a45-b6fe-1fc39044e307 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The terminal elimination half-life of irbesartan averages 11 to 15 hours.
      13. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:6916c617-92d2-44f5-b968-6267517a2ce6 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The terminal elimination half-life of irbesartan averages 11 to 15 hours.
      14. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:61ab1b6e-c849-49ca-a3f0-150774db649d (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The terminal elimination half-life of irbesartan averages 11 to 15 hours.
      15. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:2d80abcb-c995-82bc-e063-6294a90aa530 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The terminal elimination half-life of irbesartan averages 11 to 15 hours.
      16. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:950e33da-5e77-40df-b73b-dd084b36a804 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The terminal elimination half-life of irbesartan averages 11 to 15 hours.
      17. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:b587d89b-8ff9-4180-b31a-bbff5d365a1d (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The terminal elimination half-life of irbesartan averages 11 to 15 hours.
      18. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:029a90b6-0722-49be-8400-3ec29526aafd (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The terminal elimination half-life of irbesartan averages 11 to 15 hours.
      19. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:5b259fdd-ca4c-49c9-a50d-86066f5b0746 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The terminal elimination half-life of irbesartan averages 11 to 15 hours.
      20. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:efcd5f2e-1837-44ae-bc91-410c4d8b27c7 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The terminal elimination half-life of irbesartan averages 11 to 15 hours.
      21. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:14d85774-2d74-4300-b4bb-c2836db4d5bd (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The terminal elimination half-life of irbesartan averages 11 to 15 hours.
      22. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:44b72da1-4434-461f-8e3c-264ad46f85df (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The terminal elimination half-life of irbesartan averages 11 to 15 hours.
      23. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:8c9bb449-6341-4f24-9d38-6ca952e07122 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The terminal elimination half-life of irbesartan averages 11 to 15 hours.
      24. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:197871da-e0c5-49a9-8dd0-34a8c2685c6b (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The terminal elimination half-life of irbesartan averages 11 to 15 hours.
      25. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:21dd9a41-93c7-470c-94ed-f4c24e3d5633 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The terminal elimination half-life of irbesartan averages 11 to 15 hours.
      26. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:7885b2a8-be4e-48ab-8113-4e6ab791eb98 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The terminal elimination half-life of irbesartan averages 11 to 15 hours.
      27. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:fdf196d5-e933-49de-9c4c-bde50149c7d4 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The terminal elimination half-life of irbesartan averages 11 to 15 hours.
      28. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:83f5d5c8-27c0-4208-a291-0c4aa55a1ff5 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The terminal elimination half-life of irbesartan averages 11 to 15 hours.
      29. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:0898f423-0aa9-409c-8d4e-1349b59141d1 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The terminal elimination half-life of irbesartan averages 11 to 15 hours.
      30. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:e8635a1c-ae06-4e23-99f7-e704f91d6f43 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The terminal elimination half-life of irbesartan averages 11 to 15 hours.
      31. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:5c125c2a-a709-4cf1-b2d5-6e1d24a77377 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The terminal elimination half-life of irbesartan averages 11 to 15 hours.
      32. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:61b60f94-35e6-b90b-08ce-fbb2fe011f34 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The terminal elimination half-life of irbesartan averages 11 to 15 hours.
      33. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:1f98fd95-e564-45b3-947f-45eba77f2af5 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The terminal elimination half-life of irbesartan averages 11 to 15 hours.
      34. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:7e0ddb7b-80c5-47ab-afee-c74bb735e829 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The terminal elimination half-life of irbesartan averages 11 to 15 hours.
      35. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:0c1fc197-c2d9-453c-b79f-b53de89c188b (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The terminal elimination half-life of irbesartan averages 11 to 15 hours.
      36. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:70a25c6d-23ce-488c-9ef8-62b3b99e5052 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The terminal elimination half-life of irbesartan averages 11 to 15 hours.
      37. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:bc07bbf5-b1c6-4854-b6af-e06520c20728 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The terminal elimination half-life of irbesartan averages 11 to 15 hours.
      38. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:068224c4-a34d-32d7-bb2a-7eed44ccf7d3 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The terminal elimination half-life of irbesartan averages 11 to 15 hours.
      39. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:9adacfa2-2814-4deb-9e34-c3b3c8dcd41a (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The terminal elimination half-life of irbesartan averages 11 to 15 hours.
      40. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:6babdb48-8384-49ce-a759-d380d79a4010 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The terminal elimination half-life of irbesartan averages 11 to 15 hours.
      41. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:ada35ec2-8472-411a-8e7c-ff1a0df94ab5 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The terminal elimination half-life of irbesartan averages 11 to 15 hours.
      42. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:ed789dc1-0b39-4efc-990d-7b6b43a8b3ba (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The terminal elimination half-life of irbesartan averages 11 to 15 hours.
      43. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:bb58acb0-2dc0-45ee-86bb-b405b1b75cff (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The terminal elimination half-life of irbesartan averages 11 to 15 hours.
      44. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:9b8581c1-d052-4fe2-a9fc-cf7adf0f9061 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The terminal elimination half-life of irbesartan averages 11 to 15 hours.
    2. 11 hours

      Numeric value
      11
      Unit
      hours
      Source records
      1

      Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.

      Show all 1 source records
      1. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:ddca7d7c-07fe-4df6-83ae-a9c05048b66e (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The terminal elimination half-life of irbesartan averages 11 hours to 15 hours.
  4. Projected row 774

    Medicine slug
    irbesartan
    Compared field
    tMax
    Comparison state
    insufficient_context
    Reason codes
    • STRUCTURED_CONTEXT_MISSING
    Documents examined
    45
    Source count
    45
    Agreement rate
    0.977778
    Recorded readings
    1. 1.5 to 2 hours

      Numeric value
      1.5
      Unit
      hours
      Source records
      44

      Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.

      Show all 44 source records
      1. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:1ab1ff46-d0b1-4762-9ebf-3e07dde8b048 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        Following oral administration of irbesartan tablets, peak plasma concentrations of irbesartan are attained at 1.5 to 2 hours after dosing.
      2. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:868bd0a7-38ff-4722-8063-a697af3be527 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        Following oral administration of irbesartran, peak plasma concentrations of irbesartan are attained at 1.5 to 2 hours after dosing.
      3. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:a7c093c2-3eef-4956-8a14-c36aada0304f (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        Following oral administration of irbesartan, peak plasma concentrations of irbesartan are attained at 1.5 to 2 hours after dosing.
      4. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:6eb0cb56-2e51-45ef-9fd5-5646cf9f78a3 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        Following oral administration of irbesartan tablets, peak plasma concentrations of irbesartan are attained at 1.5 to 2 hours after dosing.
      5. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:f0ec2ccc-7d79-4cde-a13e-08faeea4e934 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        Following oral administration of irbesartan tablets, peak plasma concentrations of irbesartan are attained at 1.5 to 2 hours after dosing.
      6. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:9644fa38-dd28-4888-9d55-80967c4fc8d7 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        Following oral administration of irbesartran, peak plasma concentrations of irbesartan are attained at 1.5 to 2 hours after dosing.
      7. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:08c85ada-de6f-4cff-bc81-2332a22bef45 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        Following oral administration of irbesartan tablets, peak plasma concentrations of irbesartan are attained at 1.5 to 2 hours after dosing.
      8. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:0f3408b4-44be-4a92-a59f-9b5a9716bc9a (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        Following oral administration of irbesartan, peak plasma concentrations of irbesartan are attained at 1.5 to 2 hours after dosing.
      9. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:ecc490ea-a68e-4261-8be2-5020ac5ab803 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        Following oral administration of irbesartan tablets, peak plasma concentrations of irbesartan are attained at 1.5 to 2 hours after dosing.
      10. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:bfdf76ae-fedf-630c-e053-2995a90a9868 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        Following oral administration of irbesartran, peak plasma concentrations of irbesartan are attained at 1.5 to 2 hours after dosing.
      11. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:2113a901-2612-4557-b86d-3afc006fb8bb (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        Following oral administration of irbesartan, peak plasma concentrations of irbesartan are attained at 1.5 to 2 hours after dosing.
      12. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:33416f1e-adee-4a45-b6fe-1fc39044e307 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        Following oral administration of irbesartan, peak plasma concentrations of irbesartan are attained at 1.5 to 2 hours after dosing.
      13. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:6916c617-92d2-44f5-b968-6267517a2ce6 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        Following oral administration of irbesartan tablets, peak plasma concentrations of irbesartan are attained at 1.5 to 2 hours after dosing.
      14. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:61ab1b6e-c849-49ca-a3f0-150774db649d (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        Following oral administration of irbesartan, peak plasma concentrations of irbesartan are attained at 1.5 to 2 hours after dosing.
      15. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:2d80abcb-c995-82bc-e063-6294a90aa530 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        Following oral administration of irbesartan, peak plasma concentrations of irbesartan are attained at 1.5 to 2 hours after dosing.
      16. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:950e33da-5e77-40df-b73b-dd084b36a804 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        Following oral administration of irbesartran, peak plasma concentrations of irbesartan are attained at 1.5 to 2 hours after dosing.
      17. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:b587d89b-8ff9-4180-b31a-bbff5d365a1d (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        Following oral administration of irbesartan tablets, peak plasma concentrations of irbesartan are attained at 1.5 to 2 hours after dosing.
      18. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:029a90b6-0722-49be-8400-3ec29526aafd (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        Following oral administration of irbesartan tablets, peak plasma concentrations of irbesartan are attained at 1.5 to 2 hours after dosing.
      19. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:5b259fdd-ca4c-49c9-a50d-86066f5b0746 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        Following oral administration of irbesartan, peak plasma concentrations of irbesartan are attained at 1.5 to 2 hours after dosing.
      20. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:efcd5f2e-1837-44ae-bc91-410c4d8b27c7 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        Following oral administration of irbesartan tablets, peak plasma concentrations of irbesartan are attained at 1.5 to 2 hours after dosing.
      21. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:14d85774-2d74-4300-b4bb-c2836db4d5bd (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        Following oral administration of irbesartan tablets, peak plasma concentrations of irbesartan are attained at 1.5 to 2 hours after dosing.
      22. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:44b72da1-4434-461f-8e3c-264ad46f85df (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        Following oral administration of irbesartan tablets, peak plasma concentrations of irbesartan are attained at 1.5 to 2 hours after dosing.
      23. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:8c9bb449-6341-4f24-9d38-6ca952e07122 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        Following oral administration of irbesartan, peak plasma concentrations of irbesartan are attained at 1.5 to 2 hours after dosing.
      24. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:197871da-e0c5-49a9-8dd0-34a8c2685c6b (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        Following oral administration of irbesartran, peak plasma concentrations of irbesartan are attained at 1.5 to 2 hours after dosing.
      25. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:21dd9a41-93c7-470c-94ed-f4c24e3d5633 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        Following oral administration of irbesartran, peak plasma concentrations of irbesartan are attained at 1.5 to 2 hours after dosing.
      26. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:7885b2a8-be4e-48ab-8113-4e6ab791eb98 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        Following oral administration of AVAPRO, peak plasma concentrations of irbesartan are attained at 1.5 to 2 hours after dosing.
      27. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:fdf196d5-e933-49de-9c4c-bde50149c7d4 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        Following oral administration of irbesartan, peak plasma concentrations of irbesartan are attained at 1.5 to 2 hours after dosing.
      28. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:83f5d5c8-27c0-4208-a291-0c4aa55a1ff5 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        Following oral administration of irbesartan tablets, peak plasma concentrations of irbesartan are attained at 1.5 to 2 hours after dosing.
      29. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:0898f423-0aa9-409c-8d4e-1349b59141d1 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        Following oral administration of Irbesartan Tablets, peak plasma concentrations of irbesartan are attained at 1.5 to 2 hours after dosing.
      30. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:e8635a1c-ae06-4e23-99f7-e704f91d6f43 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        Following oral administration of irbesartan tablets, peak plasma concentrations of irbesartan are attained at 1.5 to 2 hours after dosing.
      31. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:5c125c2a-a709-4cf1-b2d5-6e1d24a77377 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        Following oral administration of irbesartran, peak plasma concentrations of irbesartan are attained at 1.5 to 2 hours after dosing.
      32. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:61b60f94-35e6-b90b-08ce-fbb2fe011f34 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        Following oral administration of irbesartran, peak plasma concentrations of irbesartan are attained at 1.5 to 2 hours after dosing.
      33. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:1f98fd95-e564-45b3-947f-45eba77f2af5 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        Following oral administration of irbesartan, peak plasma concentrations of irbesartan are attained at 1.5 to 2 hours after dosing.
      34. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:7e0ddb7b-80c5-47ab-afee-c74bb735e829 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        Following oral administration of irbesartran, peak plasma concentrations of irbesartan are attained at 1.5 to 2 hours after dosing.
      35. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:0c1fc197-c2d9-453c-b79f-b53de89c188b (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        Following oral administration of irbesartan, peak plasma concentrations of irbesartan are attained at 1.5 to 2 hours after dosing.
      36. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:70a25c6d-23ce-488c-9ef8-62b3b99e5052 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        Following oral administration of irbesartan tablets, peak plasma concentrations of irbesartan are attained at 1.5 to 2 hours after dosing.
      37. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:bc07bbf5-b1c6-4854-b6af-e06520c20728 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        Following oral administration of irbesartan tablets, peak plasma concentrations of irbesartan are attained at 1.5 to 2 hours after dosing.
      38. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:068224c4-a34d-32d7-bb2a-7eed44ccf7d3 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        Following oral administration of irbesartan, peak plasma concentrations of irbesartan are attained at 1.5 to 2 hours after dosing.
      39. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:9adacfa2-2814-4deb-9e34-c3b3c8dcd41a (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        Following oral administration of irbesartan tablets, peak plasma concentrations of irbesartan are attained at 1.5 to 2 hours after dosing.
      40. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:6babdb48-8384-49ce-a759-d380d79a4010 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        Following oral administration of irbesartan tablets, peak plasma concentrations of irbesartan are attained at 1.5 to 2 hours after dosing.
      41. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:ada35ec2-8472-411a-8e7c-ff1a0df94ab5 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        Following oral administration of irbesartan tablets, peak plasma concentrations of irbesartan are attained at 1.5 to 2 hours after dosing.
      42. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:ed789dc1-0b39-4efc-990d-7b6b43a8b3ba (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        Following oral administration of irbesartan tablets, peak plasma concentrations of irbesartan are attained at 1.5 to 2 hours after dosing.
      43. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:bb58acb0-2dc0-45ee-86bb-b405b1b75cff (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        Following oral administration of irbesartan, peak plasma concentrations of irbesartan are attained at 1.5 to 2 hours after dosing.
      44. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:9b8581c1-d052-4fe2-a9fc-cf7adf0f9061 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        Following oral administration of irbesartran, peak plasma concentrations of irbesartan are attained at 1.5 to 2 hours after dosing.
    2. 1.5 hours

      Numeric value
      1.5
      Unit
      hours
      Source records
      1

      Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.

      Show all 1 source records
      1. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:ddca7d7c-07fe-4df6-83ae-a9c05048b66e (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        Following oral administration of irbesartan, peak plasma concentrations of irbesartan are attained at 1.5 hours to 2 hours after dosing.
  5. Projected row 775

    Medicine slug
    irbesartan
    Compared field
    volumeOfDistribution
    Comparison state
    insufficient_context
    Reason codes
    • STRUCTURED_CONTEXT_MISSING
    Documents examined
    45
    Source count
    45
    Agreement rate
    0.977778
    Recorded readings
    1. 53 to 93 liters

      Numeric value
      53
      Unit
      L
      Source records
      44

      Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.

      Show all 44 source records
      1. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:1ab1ff46-d0b1-4762-9ebf-3e07dde8b048 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The average volume of distribution is 53 to 93 liters.
      2. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:868bd0a7-38ff-4722-8063-a697af3be527 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The average volume of distribution is 53 to 93 liters.
      3. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:a7c093c2-3eef-4956-8a14-c36aada0304f (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The average volume of distribution is 53 to 93 liters.
      4. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:6eb0cb56-2e51-45ef-9fd5-5646cf9f78a3 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The average volume of distribution is 53 to 93 liters.
      5. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:f0ec2ccc-7d79-4cde-a13e-08faeea4e934 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The average volume of distribution is 53 to 93 liters.
      6. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:9644fa38-dd28-4888-9d55-80967c4fc8d7 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The average volume of distribution is 53 to 93 liters.
      7. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:08c85ada-de6f-4cff-bc81-2332a22bef45 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The average volume of distribution is 53 to 93 liters.
      8. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:0f3408b4-44be-4a92-a59f-9b5a9716bc9a (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The average volume of distribution is 53 to 93 liters.
      9. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:ecc490ea-a68e-4261-8be2-5020ac5ab803 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The average volume of distribution is 53 to 93 liters.
      10. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:bfdf76ae-fedf-630c-e053-2995a90a9868 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The average volume of distribution is 53 to 93 liters.
      11. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:2113a901-2612-4557-b86d-3afc006fb8bb (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The average volume of distribution is 53 to 93 liters.
      12. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:33416f1e-adee-4a45-b6fe-1fc39044e307 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The average volume of distribution is 53 to 93 liters.
      13. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:6916c617-92d2-44f5-b968-6267517a2ce6 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The average volume of distribution is 53 to 93 liters.
      14. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:61ab1b6e-c849-49ca-a3f0-150774db649d (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The average volume of distribution is 53 to 93 liters.
      15. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:2d80abcb-c995-82bc-e063-6294a90aa530 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The average volume of distribution is 53 to 93 liters.
      16. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:950e33da-5e77-40df-b73b-dd084b36a804 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The average volume of distribution is 53 to 93 liters.
      17. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:b587d89b-8ff9-4180-b31a-bbff5d365a1d (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The average volume of distribution is 53 to 93 liters.
      18. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:029a90b6-0722-49be-8400-3ec29526aafd (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The average volume of distribution is 53 to 93 liters.
      19. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:5b259fdd-ca4c-49c9-a50d-86066f5b0746 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The average volume of distribution is 53 to 93 liters.
      20. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:efcd5f2e-1837-44ae-bc91-410c4d8b27c7 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The average volume of distribution is 53 to 93 liters.
      21. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:14d85774-2d74-4300-b4bb-c2836db4d5bd (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The average volume of distribution is 53 to 93 liters.
      22. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:44b72da1-4434-461f-8e3c-264ad46f85df (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The average volume of distribution is 53 to 93 liters.
      23. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:8c9bb449-6341-4f24-9d38-6ca952e07122 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The average volume of distribution is 53 to 93 liters.
      24. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:197871da-e0c5-49a9-8dd0-34a8c2685c6b (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The average volume of distribution is 53 to 93 liters.
      25. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:21dd9a41-93c7-470c-94ed-f4c24e3d5633 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The average volume of distribution is 53 to 93 liters.
      26. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:7885b2a8-be4e-48ab-8113-4e6ab791eb98 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The average volume of distribution is 53 to 93 liters.
      27. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:fdf196d5-e933-49de-9c4c-bde50149c7d4 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The average volume of distribution is 53 to 93 liters.
      28. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:83f5d5c8-27c0-4208-a291-0c4aa55a1ff5 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The average volume of distribution is 53 to 93 liters.
      29. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:0898f423-0aa9-409c-8d4e-1349b59141d1 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The average volume of distribution is 53 to 93 liters.
      30. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:e8635a1c-ae06-4e23-99f7-e704f91d6f43 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The average volume of distribution is 53 to 93 liters.
      31. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:5c125c2a-a709-4cf1-b2d5-6e1d24a77377 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The average volume of distribution is 53 to 93 liters.
      32. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:61b60f94-35e6-b90b-08ce-fbb2fe011f34 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The average volume of distribution is 53 to 93 liters.
      33. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:1f98fd95-e564-45b3-947f-45eba77f2af5 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The average volume of distribution is 53 to 93 liters.
      34. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:7e0ddb7b-80c5-47ab-afee-c74bb735e829 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The average volume of distribution is 53 to 93 liters.
      35. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:0c1fc197-c2d9-453c-b79f-b53de89c188b (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The average volume of distribution is 53 to 93 liters.
      36. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:70a25c6d-23ce-488c-9ef8-62b3b99e5052 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The average volume of distribution is 53 to 93 liters.
      37. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:bc07bbf5-b1c6-4854-b6af-e06520c20728 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The average volume of distribution is 53 to 93 liters.
      38. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:068224c4-a34d-32d7-bb2a-7eed44ccf7d3 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The average volume of distribution is 53 to 93 liters.
      39. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:9adacfa2-2814-4deb-9e34-c3b3c8dcd41a (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The average volume of distribution is 53 to 93 liters.
      40. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:6babdb48-8384-49ce-a759-d380d79a4010 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The average volume of distribution is 53 to 93 liters.
      41. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:ada35ec2-8472-411a-8e7c-ff1a0df94ab5 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The average volume of distribution is 53 to 93 liters.
      42. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:ed789dc1-0b39-4efc-990d-7b6b43a8b3ba (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The average volume of distribution is 53 to 93 liters.
      43. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:bb58acb0-2dc0-45ee-86bb-b405b1b75cff (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The average volume of distribution is 53 to 93 liters.
      44. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:9b8581c1-d052-4fe2-a9fc-cf7adf0f9061 (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The average volume of distribution is 53 to 93 liters.
    2. 53 liters

      Numeric value
      53
      Unit
      L
      Source records
      1

      Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.

      Show all 1 source records
      1. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:ddca7d7c-07fe-4df6-83ae-a9c05048b66e (opens source in a new tab)

        Irbesartan label

        Version not recorded · Effective date not recorded

        The average volume of distribution is 53 liters to 93 liters.
  6. Projected row 776

    Medicine slug
    irinotecan
    Compared field
    halfLife
    Comparison state
    agree
    Reason codes
    • COMPATIBLE_VALUES_OVERLAP
    Documents examined
    16
    Source count
    15
    Agreement rate
    1
    Recorded readings
    1. 6 to 12 hours

      Numeric value
      6
      Unit
      hours
      Source records
      15

      Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.

      Show all 15 source records
      1. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:d04f2471-3085-4fc8-a657-bb3918d48e6e (opens source in a new tab)

        Irinotecan label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics After intravenous infusion of irinotecan in humans, irinotecan plasma concentrations decline in a multiexponential manner, with a mean terminal elimination half-life of about 6 to 12 hours.
      2. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:9c6aa884-750e-4b11-9955-bc7ab6e9c2ad (opens source in a new tab)

        Irinotecan label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics After intravenous infusion of irinotecan in humans, irinotecan plasma concentrations decline in a multiexponential manner, with a mean terminal elimination half-life of about 6 to 12 hours.
      3. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:85ed6019-f462-4abe-a89e-ad991623c86d (opens source in a new tab)

        Irinotecan label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics After intravenous infusion of irinotecan in humans, irinotecan plasma concentrations decline in a multiexponential manner, with a mean terminal elimination half-life of about 6 to 12 hours.
      4. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:5c527c2e-9062-4afe-dbbb-f650db3a340f (opens source in a new tab)

        Irinotecan label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics After intravenous infusion of irinotecan in humans, irinotecan plasma concentrations decline in a multiexponential manner, with a mean terminal elimination half-life of about 6 to 12 hours.
      5. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:8fe98987-e526-4729-a8f4-c7230f424108 (opens source in a new tab)

        Irinotecan label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics After intravenous infusion of irinotecan in humans, irinotecan plasma concentrations decline in a multiexponential manner, with a mean terminal elimination half-life of about 6 to 12 hours.
      6. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:ee45f127-8450-4455-a945-a1f5707f1d39 (opens source in a new tab)

        Irinotecan label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics After intravenous infusion of irinotecan in humans, irinotecan plasma concentrations decline in a multiexponential manner, with a mean terminal elimination half-life of about 6 to 12 hours.
      7. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:de634e80-328a-4473-b395-0172683a2411 (opens source in a new tab)

        Irinotecan label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics After intravenous infusion of irinotecan in humans, irinotecan plasma concentrations decline in a multiexponential manner, with a mean terminal elimination half-life of about 6 to 12 hours.
      8. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:b26e5d27-dba5-7538-9e7b-48b358998cbb (opens source in a new tab)

        Irinotecan label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics After intravenous infusion of irinotecan in humans, irinotecan plasma concentrations decline in a multiexponential manner, with a mean terminal elimination half-life of about 6 to 12 hours.
      9. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:e518dfc6-7e93-4fee-a66c-51e1ab71c056 (opens source in a new tab)

        Irinotecan label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics After intravenous infusion of irinotecan in humans, irinotecan plasma concentrations decline in a multiexponential manner, with a mean terminal elimination half-life of about 6 to 12 hours.
      10. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:5e1fdcaa-918f-4cd8-9c7a-4c538d866198 (opens source in a new tab)

        Irinotecan label

        Version not recorded · Effective date not recorded

        Administration of irinotecan has resulted in antitumor activity in mice bearing cancers of rodent origin and in human carcinoma xenografts of various histological types. 12.3 Pharmacokinetics After intravenous infusion of irinotecan in humans, irinotecan plasma concentrations decline in a multiexponential manner, with a mean terminal elimination half-life of about 6 to 12 hours.
      11. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:afcdde49-ec0c-4c56-a1af-2917185b1a08 (opens source in a new tab)

        Irinotecan label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics After intravenous infusion of irinotecan in humans, irinotecan plasma concentrations decline in a multiexponential manner, with a mean terminal elimination half-life of about 6 to 12 hours.
      12. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:4f98e9ed-f7b1-5346-af72-fccb0abf3f4b (opens source in a new tab)

        Irinotecan label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics After intravenous infusion of irinotecan in humans, irinotecan plasma concentrations decline in a multiexponential manner, with a mean terminal elimination half-life of about 6 to 12 hours.
      13. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:7a30d551-9ea7-47ea-9073-f541bff457a3 (opens source in a new tab)

        Irinotecan label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics After intravenous infusion of irinotecan in humans, irinotecan plasma concentrations decline in a multiexponential manner, with a mean terminal elimination half-life of about 6 to 12 hours.
      14. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:be716692-6b4f-47b6-83d1-01665861626b (opens source in a new tab)

        Irinotecan label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics After intravenous infusion of irinotecan in humans, irinotecan plasma concentrations decline in a multiexponential manner, with a mean terminal elimination half-life of about 6 to 12 hours.
      15. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:caab50e6-0dad-4ddd-9a6c-96cc2b87aee7 (opens source in a new tab)

        Irinotecan label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics After intravenous infusion of irinotecan in humans, irinotecan plasma concentrations decline in a multiexponential manner, with a mean terminal elimination half-life of about 6 to 12 hours.
  7. Projected row 777

    Medicine slug
    irinotecan
    Compared field
    proteinBinding
    Comparison state
    insufficient_context
    Reason codes
    • STRUCTURED_CONTEXT_MISSING
    Documents examined
    16
    Source count
    16
    Agreement rate
    0.875
    Recorded readings
    1. 30%

      Numeric value
      30
      Unit
      %
      Source records
      14

      Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.

      Show all 14 source records
      1. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:d04f2471-3085-4fc8-a657-bb3918d48e6e (opens source in a new tab)

        Irinotecan label

        Version not recorded · Effective date not recorded

        5 13.3±6.01 26.3±11.9 229±108 10.4 a ±3.1 340 (N=6) 3,392 ±874 20,604 ±6,027 11.7 b ±1.0 234 ±69.6 13.9 ±4.0 56.0 ±28.2 474 ±245 21.0 b ±4.3 Distribution Irinotecan exhibits moderate plasma protein binding (30% to 68% bound).
      2. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:9c6aa884-750e-4b11-9955-bc7ab6e9c2ad (opens source in a new tab)

        Irinotecan label

        Version not recorded · Effective date not recorded

        nute infusion t 1/2 - Terminal elimination half-life Vz - Volume of distribution of terminal elimination phase CL - Total systemic clearance Distribution Irinotecan exhibits moderate plasma protein binding (30% to 68% bound).
      3. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:85ed6019-f462-4abe-a89e-ad991623c86d (opens source in a new tab)

        Irinotecan label

        Version not recorded · Effective date not recorded

        3 ±6.01 26.3 ±11.9 229 ±108 10.4 a ±3.1 340 (N = 6) 3,392 ±874 20,604 ±6,027 11.7 b ±1.0 234 ±69.6 13.9 ±4.0 56.0 ±28.2 474 ±245 21.0 b ±4.3 Distribution Irinotecan exhibits moderate plasma protein binding (30% to 68% bound).
      4. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:5c527c2e-9062-4afe-dbbb-f650db3a340f (opens source in a new tab)

        Irinotecan label

        Version not recorded · Effective date not recorded

        Because of the longer collection period, these values provide a more accurate reflection of the terminal elimination half-lives of irinotecan and SN-38. ±1.0 234 ±69.6 13.9 ±4.0 56.0 ±28.2 474 ±245 21.0 ±4.3 Distribution Irinotecan exhibits moderate plasma protein binding (30% to 68% bound).
      5. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:8fe98987-e526-4729-a8f4-c7230f424108 (opens source in a new tab)

        Irinotecan label

        Version not recorded · Effective date not recorded

        3 ±6.01 26.3 ±11.9 229 ±108 10.4 a ±3.1 340 (N = 6) 3,392 ±874 20,604 ±6,027 11.7 b ±1.0 234 ±69.6 13.9 ±4.0 56.0 ±28.2 474 ±245 21.0 b ±4.3 Distribution Irinotecan exhibits moderate plasma protein binding (30% to 68% bound).
      6. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:ee45f127-8450-4455-a945-a1f5707f1d39 (opens source in a new tab)

        Irinotecan label

        Version not recorded · Effective date not recorded

        ±3,270 ±0.7 ±48.5 ±6.01 ±11.9 ±108 ±3.1 340 3,392 20,604 1 l.7 b 234 13.9 56.0 474 21.0 b (N=6) ±874 ±6,027 ±1.0 ±69.6 ±4.0 ±28.2 ±245 ±4.3 Distribution Irinotecan exhibits moderate plasma protein binding (30% to 68% bound).
      7. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:de634e80-328a-4473-b395-0172683a2411 (opens source in a new tab)

        Irinotecan label

        Version not recorded · Effective date not recorded

        Distribution Irinotecan exhibits moderate plasma protein binding (30% to 68% bound).
      8. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:b26e5d27-dba5-7538-9e7b-48b358998cbb (opens source in a new tab)

        Irinotecan label

        Version not recorded · Effective date not recorded

        Distribution Irinotecan exhibits moderate plasma protein binding (30% to 68% bound).
      9. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:e518dfc6-7e93-4fee-a66c-51e1ab71c056 (opens source in a new tab)

        Irinotecan label

        Version not recorded · Effective date not recorded

        Because of the longer collection period, these values provide a more accurate reflection of the terminal elimination half-lives of irinotecan and SN-38. ±1.0 234 ±69.6 13.9 ±4.0 56.0 ±28.2 474 ±245 21.0 ±4.3 Distribution Irinotecan exhibits moderate plasma protein binding (30% to 68% bound).
      10. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:afcdde49-ec0c-4c56-a1af-2917185b1a08 (opens source in a new tab)

        Irinotecan label

        Version not recorded · Effective date not recorded

        3 ±6.01 26.3 ±11.9 229 ±108 10.4 a ±3.1 340 (N = 6) 3,392 ±874 20,604 ±6,027 11.7 b ±1.0 234 ±69.6 13.9 ±4.0 56.0 ±28.2 474 ±245 21.0 b ±4.3 Distribution Irinotecan exhibits moderate plasma protein binding (30% to 68% bound).
      11. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:4f98e9ed-f7b1-5346-af72-fccb0abf3f4b (opens source in a new tab)

        Irinotecan label

        Version not recorded · Effective date not recorded

        Distribution Irinotecan exhibits moderate plasma protein binding (30% to 68% bound).
      12. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:7a30d551-9ea7-47ea-9073-f541bff457a3 (opens source in a new tab)

        Irinotecan label

        Version not recorded · Effective date not recorded

        6.3 ± 11.9 229 ± 108 10.4 a ± 3.1 340 (N=6) 3,392 ± 874 20,604 ± 6,027 11.7 b ± 1.0 234 ± 69.6 13.9 ± 4.0 56.0 ± 28.2 474 ± 245 21.0 b ± 4.3 Distribution Irinotecan exhibits moderate plasma protein binding (30% to 68% bound).
      13. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:be716692-6b4f-47b6-83d1-01665861626b (opens source in a new tab)

        Irinotecan label

        Version not recorded · Effective date not recorded

        nute infusion t 1/2 - Terminal elimination half-life Vz - Volume of distribution of terminal elimination phase CL - Total systemic clearance Distribution Irinotecan exhibits moderate plasma protein binding (30% to 68% bound).
      14. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:caab50e6-0dad-4ddd-9a6c-96cc2b87aee7 (opens source in a new tab)

        Irinotecan label

        Version not recorded · Effective date not recorded

        3.3 ±6.01 26.3 ±11.9 229 ±108 10.4 a ±3.1 340 (N=6) 3,392 ±874 20,604 ±6,027 11.7 b ±1.0 234 ±69.6 13.9 ±4.0 56.0 ±28.2 474 ±245 21.0 b ±4.3 Distribution Irinotecan exhibits moderate plasma protein binding (30% to 68% bound).
    2. 0.44%

      Numeric value
      0.44
      Unit
      %
      Source records
      1

      Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.

      Show all 1 source records
      1. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:c8b58efa-1820-48a4-b70d-62918fc4abfc (opens source in a new tab)

        Irinotecan label

        Version not recorded · Effective date not recorded

        Plasma protein binding is <0.44% of the total irinotecan in ONIVYDE.
    3. 50%

      Numeric value
      50
      Unit
      %
      Source records
      1

      Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.

      Show all 1 source records
      1. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:5e1fdcaa-918f-4cd8-9c7a-4c538d866198 (opens source in a new tab)

        Irinotecan label

        Version not recorded · Effective date not recorded

        In vitro cytotoxicity assays show that the potency of SN-38 relative to irinotecan varies from 2- to 2000-fold; however, the plasma area under the concentration versus time curve (AUC) values for SN-38 are 2% to 8% of irinotecan and SN-38 is 95% bound to plasma proteins compared to approximately 50% bound to plasma proteins for irinotecan [see Clinical Pharmacology (12.3) ] .
  8. Projected row 778

    Medicine slug
    iron-dextran
    Compared field
    halfLife
    Comparison state
    agree
    Reason codes
    • COMPATIBLE_VALUES_OVERLAP
    Documents examined
    3
    Source count
    3
    Agreement rate
    1
    Recorded readings
    1. 5 hours

      Numeric value
      5
      Unit
      hours
      Source records
      3

      Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.

      Show all 3 source records
      1. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:99bf34be-cb8a-46d1-9637-5544dc2da287 (opens source in a new tab)

        Iron Dextran label

        Version not recorded · Effective date not recorded

        Various studies involving intravenously administered 59 Fe iron dextran to iron deficient subjects, some of whom had coexisting disease, have yielded half-life values ranging from 5 hours to more than 20 hours.
      2. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:9a4cd424-865d-fdd1-e053-2995a90a00ff (opens source in a new tab)

        Iron Dextran label

        Version not recorded · Effective date not recorded

        Various studies involving intravenously administered 59Fe iron dextran to iron deficient subjects, some of whom had coexisting diseases, have yielded half-life values ranging from 5 hours to more than 20 hours.
      3. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:94b01b1e-794b-4bea-8e24-2e54683fc023 (opens source in a new tab)

        Iron Dextran label

        Version not recorded · Effective date not recorded

        Various studies involving intravenously administered 59 Fe iron dextran to iron deficient subjects, some of whom had coexisting disease, have yielded half-life values ranging from 5 hours to more than 20 hours.
  9. Projected row 779

    Medicine slug
    iron-sucrose
    Compared field
    halfLife
    Comparison state
    agree
    Reason codes
    • COMPATIBLE_VALUES_OVERLAP
    Documents examined
    6
    Source count
    6
    Agreement rate
    1
    Recorded readings
    1. 6 h

      Numeric value
      6
      Unit
      hours
      Source records
      6

      Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.

      Show all 6 source records
      1. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:78c04f10-0489-4e45-8cb5-28a6789d1149 (opens source in a new tab)

        Iron Sucrose label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics In healthy adults administered intravenous doses of iron sucrose, its iron component exhibited first order kinetics with an elimination half-life of 6 h, total clearance of 1.2 L/h, and steady state apparent volume of distribution of 7.9 L.
      2. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:6f19c80e-22e9-4bab-aa53-4d2d958119ed (opens source in a new tab)

        Iron Sucrose label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics In healthy adults administered intravenous doses of Iron Sucrose Injection, its iron component exhibited first order kinetics with an elimination half-life of 6 h, total clearance of 1.2 L/h, and steady state apparent volume of distribution of 7.9 L.
      3. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:626dc9e5-c6b4-4f9c-9bf4-774fd3ae619a (opens source in a new tab)

        Iron Sucrose label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics In healthy adults administered intravenous doses of Venofer, its iron component exhibited first order kinetics with an elimination half-life of 6 h, total clearance of 1.2 L/h, and steady state apparent volume of distribution of 7.9 L.
      4. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:f1ab1a22-2b99-4d27-8b5a-9c3bcd5e3040 (opens source in a new tab)

        Iron Sucrose label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics In healthy adults administered intravenous doses of Venofer, its iron component exhibited first order kinetics with an elimination half-life of 6 h, total clearance of 1.2 L/h, and steady state apparent volume of distribution of 7.9 L.
      5. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:3f109bdb-a412-43b2-84c7-9dad05e85a71 (opens source in a new tab)

        Iron Sucrose label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics In healthy adults administered intravenous doses of iron sucrose, its iron component exhibited first order kinetics with an elimination half-life of 6 h, total clearance of 1.2 L/h, and steady state apparent volume of distribution of 7.9 L.
      6. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:b998ef36-81fa-40a1-9cd1-6d6156f91564 (opens source in a new tab)

        Iron Sucrose label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics In healthy adults administered intravenous doses of Venofer, its iron component exhibited first order kinetics with an elimination half-life of 6 h, total clearance of 1.2 L/h, and steady state apparent volume of distribution of 7.9 L.
  10. Projected row 780

    Medicine slug
    iron-sucrose
    Compared field
    volumeOfDistribution
    Comparison state
    agree
    Reason codes
    • COMPATIBLE_VALUES_OVERLAP
    Documents examined
    6
    Source count
    6
    Agreement rate
    1
    Recorded readings
    1. 7.9 L

      Numeric value
      7.9
      Unit
      L
      Source records
      6

      Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.

      Show all 6 source records
      1. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:78c04f10-0489-4e45-8cb5-28a6789d1149 (opens source in a new tab)

        Iron Sucrose label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics In healthy adults administered intravenous doses of iron sucrose, its iron component exhibited first order kinetics with an elimination half-life of 6 h, total clearance of 1.2 L/h, and steady state apparent volume of distribution of 7.9 L.
      2. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:6f19c80e-22e9-4bab-aa53-4d2d958119ed (opens source in a new tab)

        Iron Sucrose label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics In healthy adults administered intravenous doses of Iron Sucrose Injection, its iron component exhibited first order kinetics with an elimination half-life of 6 h, total clearance of 1.2 L/h, and steady state apparent volume of distribution of 7.9 L.
      3. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:626dc9e5-c6b4-4f9c-9bf4-774fd3ae619a (opens source in a new tab)

        Iron Sucrose label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics In healthy adults administered intravenous doses of Venofer, its iron component exhibited first order kinetics with an elimination half-life of 6 h, total clearance of 1.2 L/h, and steady state apparent volume of distribution of 7.9 L.
      4. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:f1ab1a22-2b99-4d27-8b5a-9c3bcd5e3040 (opens source in a new tab)

        Iron Sucrose label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics In healthy adults administered intravenous doses of Venofer, its iron component exhibited first order kinetics with an elimination half-life of 6 h, total clearance of 1.2 L/h, and steady state apparent volume of distribution of 7.9 L.
      5. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:3f109bdb-a412-43b2-84c7-9dad05e85a71 (opens source in a new tab)

        Iron Sucrose label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics In healthy adults administered intravenous doses of iron sucrose, its iron component exhibited first order kinetics with an elimination half-life of 6 h, total clearance of 1.2 L/h, and steady state apparent volume of distribution of 7.9 L.
      6. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:b998ef36-81fa-40a1-9cd1-6d6156f91564 (opens source in a new tab)

        Iron Sucrose label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics In healthy adults administered intravenous doses of Venofer, its iron component exhibited first order kinetics with an elimination half-life of 6 h, total clearance of 1.2 L/h, and steady state apparent volume of distribution of 7.9 L.

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Exact recorded field key.Values: bioavailability, halfLife, proteinBinding, tMax, volumeOfDistribution
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