Testolone (RAD-140)
Evidence: ★★★☆☆ · Status: Not Approved
In plain English
Among the most powerful SARMs. Real muscle gains, but case reports include liver injury and even myocarditis (heart-muscle inflammation).
How it works
Potent AR agonist designed to mimic testosterone's anabolism with lower prostate activity; created for muscle-wasting and breast cancer research.
Molecular target & official sources
AR (NCBI Gene) · RAD-140 (PubChem CID 118862653)
Watch out
Hepatotoxicity, documented cardiac case reports.
Helps with: Build Muscle & Strength · Recover Faster · Cardiovascular · Hormones & Testosterone
Stacks with
Shares a pathway — often paired with: Omega-3 (EPA/DHA), Vitamin D3 (+ K2), Testosterone (TRT), Finasteride / Dutasteride.
Availability & where to buy
Not widely approved. Not approved for general sale in most markets (Singapore included). Grey-market only — dose, purity and legality uncertain.
How it works: the Nuclear receptors pathway →
Common questions
Does Testolone (RAD-140) actually work?
Human-evidence rating: 3 of 5. Among the most powerful SARMs. Real muscle gains, but case reports include liver injury and even myocarditis (heart-muscle inflammation).
What are the risks or side effects of Testolone (RAD-140)?
Hepatotoxicity, documented cardiac case reports.
Is Testolone (RAD-140) legal or approved?
Regulatory status: Not Approved.