GHK-Cu (Copper Peptide)
Evidence: ★★★☆☆ · Status: Not Approved
In plain English
A copper-carrying peptide that seems to nudge thousands of genes back toward a "younger" setting — most proven for skin (collagen, wound healing). The strongest independent evidence of the cosmetic peptides; topical forms are widely sold.
How it works
Copper-binding tripeptide that, remarkably, resets gene expression — a 2010 analysis showed GHK-Cu shifts ~4,000 human genes toward a younger profile, upregulating collagen, decorin, and antioxidant/DNA-repair genes and modulating TGF-β and metalloproteinases.
Molecular target & official sources
GHK-Cu genomic review (PMC) · GHK tripeptide (PubChem CID 73587880)
Protocol
Topical serums (OTC); injectable is the reclassified/grey form.
Bottom line
Best-evidenced anti-aging peptide for skin; systemic claims less proven.
Helps with: Recover Faster · Live Longer · Skin & Hair
Availability & where to buy
Not widely approved. Not approved for general sale in most markets (Singapore included). Grey-market only — dose, purity and legality uncertain.
Used in these protocols
Common questions
Does GHK-Cu (Copper Peptide) actually work?
Human-evidence rating: 3 of 5. Best-evidenced anti-aging peptide for skin; systemic claims less proven.
How do you take GHK-Cu (Copper Peptide)?
Topical serums (OTC); injectable is the reclassified/grey form.
Is GHK-Cu (Copper Peptide) legal or approved?
Regulatory status: Not Approved.