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Collagen Peptides (+ Vitamin C)

Evidence: ★★★★☆ · Status: OTC Supplement

💡 Did you know? Collagen supplements don't travel straight to your skin — they break into peptides that signal your body to build its own collagen, with vitamin C as the cofactor.

In plain English

Feeds your tendons and ligaments their raw materials right before you stress them — timing matters, so take it ~45 min before training with vitamin C.

How it works

Hydrolysed collagen supplies glycine/proline/hydroxyproline that preferentially accumulate in tendon/ligament; taken with vitamin C (cofactor for prolyl hydroxylase) before loading, it doubles collagen-synthesis markers.

Molecular target & official sources

COL1A1 collagen type I (NCBI Gene) · P4HA1 prolyl hydroxylase (NCBI Gene)

Protocol

15 g + 50 mg vitamin C, 45–60 min pre-exercise.

Bottom line

The most practical connective-tissue supplement; timing is key. Highly relevant to running/Hyrox tendon load.

Helps with: Joint Health · Stress & Anxiety · Skin & Hair

Stacks with

Vitamin C — required to build collagen, so take them together, ideally 45–60 min before training tendons.

Availability & where to buy

Available over the counter. Widely available OTC — e.g. iHerb (ships worldwide); in Singapore also Guardian, Watsons, GNC, Shopee / Lazada. Look for a third-party-tested / GMP mark and check the dose per serving. ~S$25–45/month; unflavoured hydrolysed peptides mix into anything.

Used in these protocols

Compare Collagen Peptides (+ Vitamin C)

Common questions

Does Collagen Peptides (+ Vitamin C) actually work?

Human-evidence rating: 4 of 5. The most practical connective-tissue supplement; timing is key. Highly relevant to running/Hyrox tendon load.

How do you take Collagen Peptides (+ Vitamin C)?

15 g + 50 mg vitamin C, 45–60 min pre-exercise.

Is Collagen Peptides (+ Vitamin C) legal or approved?

Regulatory status: OTC Supplement.