Boron
Evidence: ★★★☆☆ · Status: OTC Supplement
In plain English
Most of your testosterone is "handcuffed" to a carrier protein and unusable. Boron loosens those handcuffs so more testosterone is actually active. Cheap and underused.
How it works
Trace mineral that lowers sex-hormone-binding-globulin (SHBG) — freeing bound testosterone — reduces estradiol via aromatase influence, and improves conversion of vitamin D to its active form.
Molecular target & official sources
SHBG (NCBI Gene) · Boric acid (PubChem CID 7628)
Protocol
3–10 mg/day with food. >20 mg is toxic.
Bottom line
Add 10 mg to a zinc + D3 stack — strong evidence per dollar.
Helps with: Joint Health · Hormones & Testosterone · Bone Health
The human evidence
Small human studies show a modest rise in free testosterone and a drop in inflammatory markers over ~1 week at 6–10 mg, plus a role in bone and vitamin-D/magnesium handling. Low-dose, low-risk, but effect sizes are small.
Stacks with
Vitamin D3 and magnesium (boron supports their metabolism).
Shares a pathway — often paired with: Omega-3 (EPA/DHA), Vitamin D3 (+ K2), Testosterone (TRT), Finasteride / Dutasteride.
Availability & where to buy
Available over the counter. Widely available OTC — e.g. iHerb (ships worldwide); in Singapore also Guardian, Watsons, GNC, Shopee / Lazada. Look for a third-party-tested / GMP mark and check the dose per serving. Very cheap — a year of 6 mg capsules for ~S$15–25.
How it works: the Nuclear receptors pathway →
Used in these protocols
Compare Boron
Common questions
Does Boron actually work?
Human-evidence rating: 3 of 5. Add 10 mg to a zinc + D3 stack — strong evidence per dollar.
How do you take Boron?
3–10 mg/day with food. 20 mg is toxic.
Is Boron legal or approved?
Regulatory status: OTC Supplement.