Beta-Glucans
Evidence: ★★★☆☆ · Status: OTC Supplement
💡 Did you know? The beta-glucan fibres in oats and mushrooms can 'prime' your immune cells — and the same molecule lowers cholesterol by trapping it in the gut.
In plain English
Sugars from yeast/mushrooms that "train" your first-line immune cells to respond faster. Good evidence for reducing upper-respiratory infections.
How it works
Fungal/yeast polysaccharides bind Dectin-1 (CLEC7A) and CR3 on innate immune cells, priming trained immunity.
Molecular target & official sources
CLEC7A Dectin-1 (NCBI Gene) · Beta-glucan (PubChem CID 439262)
Bottom line
Best-evidenced immune polysaccharide.
Helps with: Immunity
Availability & where to buy
Available over the counter. Widely available OTC — e.g. iHerb (ships worldwide); in Singapore also Guardian, Watsons, GNC, Shopee / Lazada. Look for a third-party-tested / GMP mark and check the dose per serving.
Used in these protocols
Compare Beta-Glucans
Common questions
Does Beta-Glucans actually work?
Human-evidence rating: 3 of 5. Best-evidenced immune polysaccharide.
Is Beta-Glucans legal or approved?
Regulatory status: OTC Supplement.