Medicine library

Browse medicines, page 4 of 8

Some records contain detailed evidence; others currently contain only basic identity and regulatory information. Reviewed conclusions appear only when they are available for a specific use and group of people.

Showing 181–240 of 475 records

Linezolid (Zyvox)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Serious infections caused by resistant Gram-positive bacteria, including MRSA and vancomycin-resistant enterococci
Lumasiran (Oxlumo)
RNA-silencing medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Primary hyperoxaluria type 1 — a genetic cause of kidney stones and kidney failure
Mesalamine (Rowasa / Canasa / Asacol / Pentasa / Lialda / Apriso)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Ulcerative colitis — inflammation and ulceration of the lining of the large bowel
Metoprolol (Lopressor (tartrate) / Toprol-XL (succinate))
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
High blood pressure, chest pain, heart failure, and the period after a heart attack
Nandrolone Decanoate (Deca-Durabolin)
Small chemical medicineWithdrawn from the marketDetailed record
Use listed on the medicine record
Anaemia of kidney failure — approved, and no longer marketed in the United States
Olpasiran (AMG 890 (investigational))
RNA-silencing medicineIn Phase 3 testingDetailed record
Use listed on the medicine record
High lipoprotein(a) — an inherited cardiovascular risk factor with no approved treatment
Ondansetron (Zofran / Zofran ODT / Zuplenz)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Being sick, or feeling sick, after chemotherapy, radiotherapy or an operation
Paroxetine (Paxil / Paxil CR / Pexeva / Brisdelle)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Depression, obsessive-compulsive disorder, panic, social anxiety, generalised anxiety and post-traumatic stress; separately, at a much lower dose, menopausal hot flushes
Phenytoin (Dilantin / Phenytek)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Generalised and focal epilepsy, seizures around brain surgery, and prolonged seizures in hospital
Rhodiola rosea (Sold as golden root or arctic root, often as the SHR-5 standardised extract)
Nutritional or plant productDietary supplement; not FDA-approved as a medicineDetailed record
Use listed on the medicine record
Marketed for fatigue and mental performance under stress
Rivaroxaban (Xarelto)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Preventing stroke in an irregular heartbeat, treating and preventing clots, and reducing events in stable artery disease
Saxagliptin (Onglyza)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Type 2 diabetes — a tablet that makes the gut hormone signal last longer
Tadalafil (Cialis)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
An enlarged prostate causing a weak stream and frequent urination — and, in the same tablet, erectile dysfunction
Verapamil (Calan / Isoptin / Verelan / Verelan PM / Covera-HS)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Chest pain, a racing or irregular heartbeat, and high blood pressure
Adapalene (Differin / Differin Gel 0.1% (over the counter) / Epiduo (with benzoyl peroxide))
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Acne
Adrafinil (CRL-40028; sold in the United States as a nootropic dietary supplement)
Small chemical medicineDietary supplement; not FDA-approved as a medicineDetailed record
Use listed on the medicine record
A prodrug of modafinil, sold as a supplement because it was never scheduled
Andexanet Alfa (Andexxa)
Protein medicineFDA accelerated approval (based on an earlier result expected to predict benefit; follow-up evidence may be required)Detailed record
Use listed on the medicine record
Switching off apixaban or rivaroxaban when someone on one of them has a bleed that will not stop
Benfluorex (Mediator)
Small chemical medicineWithdrawn from the marketDetailed record
Use listed on the medicine record
A tablet marketed for blood fats and for weight in diabetes, widely prescribed in France
Buprenorphine (Subutex / Suboxone / Butrans / Belbuca / Sublocade)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Opioid use disorder, and severe long-term pain
Calcipotriene (Dovonex / Sorilux / Calcitrene / Taclonex (with betamethasone dipropionate))
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Plaque psoriasis — the raised, red, scaly patches
Cariprazine (Vraylar)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Schizophrenia, both phases of bipolar I disorder, and depression that has not responded to an antidepressant alone
Ceftriaxone (Rocephin)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Serious bacterial infections given by injection — pneumonia, meningitis, bloodstream, bone, urinary and sexually transmitted infection
Cerivastatin (Baycol / Lipobay)
Small chemical medicineWithdrawn from the marketDetailed record
Use listed on the medicine record
A cholesterol-lowering statin
Dexamethasone (Decadron / Dexamethasone Sodium Phosphate / Maxidex / Ozurdex / Hemady)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Severe inflammation and swelling — including brain swelling, croup, some cancers, and COVID-19 severe enough to need oxygen
Diclofenac (Voltaren, Cataflam, Voltaren Arthritis Pain (topical gel), Solaraze)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Arthritis pain and inflammation
Diltiazem (Cardizem / Cardizem CD / Cardizem LA / Tiadylt / Cartia XT)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Chest pain from narrowed or spasming arteries, high blood pressure, and a heart racing out of rhythm
Elasomeran (Spikevax)
RNA medicine or vaccineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
COVID-19 prevention in older adults and people at higher risk
Enoxaparin (Lovenox)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Preventing and treating blood clots in the legs and lungs, and in heart attacks
Epinephrine (EpiPen / Auvi-Q / Adrenalin / neffy)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
A severe allergic reaction — the adrenaline pen
Fentanyl (Sublimaze (injection, NDA 016619, 1968); Duragesic (transdermal patch, NDA 019813, 1990); Actiq (oral transmucosal lozenge, NDA 020747, 1998); Fentora, Subsys, Abstral, Lazanda)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
A hospital anaesthetic and a patch for severe chronic pain. Separately, illicitly manufactured fentanyl is the drug involved in most American overdose deaths, and it is increasingly pressed into counterfeit pills
Fitusiran (Qfitlia)
RNA-silencing medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Haemophilia A or B, including when factor replacement no longer works
Glyburide (Diabeta / Micronase / Glynase PresTab (glibenclamide outside the United States))
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Type 2 diabetes — the strongest and longest-acting of the old sulfonylurea tablets
Golodirsen (Vyondys 53)
Gene-silencing medicineFDA accelerated approval (based on an earlier result expected to predict benefit; follow-up evidence may be required)Detailed record
Use listed on the medicine record
Duchenne Muscular Dystrophy (exon 53 skipping)
Hydralazine (Apresoline / Dralzine; as a fixed combination with isosorbide dinitrate, BiDil)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
High blood pressure, including when it must be brought down urgently; and, combined with a nitrate, heart failure
Hydroxychloroquine (Plaquenil / Sovuna)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Lupus, rheumatoid arthritis, and malaria where the parasite is still susceptible
Isosorbide Dinitrate (Isordil / Dilatrate-SR / Sorbitrate; as a fixed combination with hydralazine, BiDil)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Preventing angina — chest pain from narrowed heart arteries
Ketoconazole (Nizoral / Nizoral Anti-Dandruff / Extina / Xolegel / Ketoconazole shampoo 2%)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Dandruff and seborrhoeic dermatitis, and the pale or dark patches of tinea versicolor
Levetiracetam (Keppra)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Epilepsy, including focal seizures and generalised seizures
Lidocaine (Xylocaine)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Numbing part of the body for a procedure, and steadying a dangerously fast heart rhythm
Midazolam (Versed; also marketed as midazolam hydrochloride injection and in sodium chloride)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Making a person calm and drowsy for a procedure, and making sure they do not remember it
Muscimol and Ibotenic Acid (Amanita muscaria) (No approved product. Sold in the United States since about 2022 as Amanita muscaria gummies, capsules, chocolates and extracts marketed as legal or nootropic mushrooms)
Nutritional or plant productDietary supplement; not FDA-approved as a medicineDetailed record
Use listed on the medicine record
Nothing. It is the fly agaric mushroom, sold as gummies and chocolate in American smoke shops, and in one Portland analysis the products claiming to contain it did not contain it
Naltrexone (ReVia / Vivitrol)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Alcohol use disorder, and relapse prevention in opioid use disorder
Nedosiran (Rivfloza)
RNA-silencing medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Primary hyperoxaluria type 1 — a genetic cause of kidney stones and kidney failure
Nitazenes (Isotonitazene and the 2-Benzylbenzimidazole Opioids) (None. Never marketed as a medicine anywhere. Sold in the illicit supply as counterfeit tablets, in heroin substitutes and as powder)
Small chemical medicineControlled substance; no approved US useDetailed record
Use listed on the medicine record
Nothing. These are 1950s analgesic candidates that were never developed, resurfacing sixty years later in the illicit drug supply because they are easy to make and are not on the lists
Omeprazole (Prilosec / Prilosec OTC)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Heartburn, acid reflux and stomach or duodenal ulcers
Patisiran (Onpattro)
RNA-silencing medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Nerve damage caused by inherited transthyretin amyloidosis
Pergolide (Permax)
Small chemical medicineWithdrawn from the marketDetailed record
Use listed on the medicine record
A Parkinson's disease tablet taken alongside levodopa
Phytonadione (Vitamin K1) (Mephyton / AquaMEPHYTON / Konakion)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Bleeding, or a risk of bleeding, because the body cannot finish building four of its clotting proteins — from warfarin, from a newborn gut that has not started making vitamin K yet, or from a condition that stops fat being absorbed
Pitavastatin (Livalo / Zypitamag / Nikita)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
High cholesterol
Propoxyphene (Darvon, Darvocet-N (with paracetamol); co-proxamol in the United Kingdom)
Small chemical medicineWithdrawn from the marketDetailed record
Use listed on the medicine record
A weak opioid painkiller for mild to moderate pain
Raloxifene (Evista)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Thinning bones after menopause, and lowering the chance of developing one type of breast cancer
Raltegravir (Isentress and Isentress HD)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
HIV-1 infection, as part of a combination regimen
Rapacuronium (Raplon)
Small chemical medicineWithdrawn from the marketDetailed record
Use listed on the medicine record
A fast-acting muscle relaxant given at the start of anaesthesia to allow a breathing tube to be placed
Sermorelin (Geref, Geref Diagnostic (both discontinued))
Peptide medicineWithdrawn from the marketDetailed record
Use listed on the medicine record
A childhood growth drug that was approved, then pulled — now compounded for anti-ageing
Sibutramine (Meridia / Reductil)
Small chemical medicineWithdrawn from the marketDetailed record
Use listed on the medicine record
A prescription appetite suppressant for obesity
Survodutide (BI 456906 (no trade name; not approved))
Peptide medicineIn Phase 3 testingDetailed record
Use listed on the medicine record
Obesity and fatty liver disease, still in trials
Tacrolimus (Prograf / Astagraf XL / Envarsus XR / Protopic)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Stopping the body rejecting a transplanted organ, and severe eczema that has not responded to steroid creams
Terfenadine (Seldane / Triludan)
Small chemical medicineWithdrawn from the marketDetailed record
Use listed on the medicine record
A hay fever tablet that did not make you drowsy
Testosterone enanthate (Delatestryl, Xyosted; also sold as generic testosterone enanthate injection)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Testosterone replacement for men whose testicles or pituitary do not make enough
Ticagrelor (Brilinta)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Preventing heart attacks, strokes and stent clots after a heart attack or unstable angina

Linezolid (Zyvox)

Lumasiran (Oxlumo)

Mesalamine (Rowasa / Canasa / Asacol / Pentasa / Lialda / Apriso)

Metoprolol (Lopressor (tartrate) / Toprol-XL (succinate))

Nandrolone Decanoate (Deca-Durabolin)

Olpasiran (AMG 890 (investigational))

Ondansetron (Zofran / Zofran ODT / Zuplenz)

Paroxetine (Paxil / Paxil CR / Pexeva / Brisdelle)

Phenytoin (Dilantin / Phenytek)

Rhodiola rosea (Sold as golden root or arctic root, often as the SHR-5 standardised extract)

Rivaroxaban (Xarelto)

Saxagliptin (Onglyza)

Tadalafil (Cialis)

Verapamil (Calan / Isoptin / Verelan / Verelan PM / Covera-HS)

Adapalene (Differin / Differin Gel 0.1% (over the counter) / Epiduo (with benzoyl peroxide))

Adrafinil (CRL-40028; sold in the United States as a nootropic dietary supplement)

Andexanet Alfa (Andexxa)

Benfluorex (Mediator)

Buprenorphine (Subutex / Suboxone / Butrans / Belbuca / Sublocade)

Calcipotriene (Dovonex / Sorilux / Calcitrene / Taclonex (with betamethasone dipropionate))

Cariprazine (Vraylar)

Ceftriaxone (Rocephin)

Cerivastatin (Baycol / Lipobay)

Dexamethasone (Decadron / Dexamethasone Sodium Phosphate / Maxidex / Ozurdex / Hemady)

Diclofenac (Voltaren, Cataflam, Voltaren Arthritis Pain (topical gel), Solaraze)

Diltiazem (Cardizem / Cardizem CD / Cardizem LA / Tiadylt / Cartia XT)

Elasomeran (Spikevax)

Enoxaparin (Lovenox)

Epinephrine (EpiPen / Auvi-Q / Adrenalin / neffy)

Fentanyl (Sublimaze (injection, NDA 016619, 1968); Duragesic (transdermal patch, NDA 019813, 1990); Actiq (oral transmucosal lozenge, NDA 020747, 1998); Fentora, Subsys, Abstral, Lazanda)

Fitusiran (Qfitlia)

Glyburide (Diabeta / Micronase / Glynase PresTab (glibenclamide outside the United States))

Golodirsen (Vyondys 53)

Hydralazine (Apresoline / Dralzine; as a fixed combination with isosorbide dinitrate, BiDil)

Hydroxychloroquine (Plaquenil / Sovuna)

Isosorbide Dinitrate (Isordil / Dilatrate-SR / Sorbitrate; as a fixed combination with hydralazine, BiDil)

Ketoconazole (Nizoral / Nizoral Anti-Dandruff / Extina / Xolegel / Ketoconazole shampoo 2%)

Levetiracetam (Keppra)

Lidocaine (Xylocaine)

Midazolam (Versed; also marketed as midazolam hydrochloride injection and in sodium chloride)

Muscimol and Ibotenic Acid (Amanita muscaria) (No approved product. Sold in the United States since about 2022 as Amanita muscaria gummies, capsules, chocolates and extracts marketed as legal or nootropic mushrooms)

Naltrexone (ReVia / Vivitrol)

Nedosiran (Rivfloza)

Nitazenes (Isotonitazene and the 2-Benzylbenzimidazole Opioids) (None. Never marketed as a medicine anywhere. Sold in the illicit supply as counterfeit tablets, in heroin substitutes and as powder)

Omeprazole (Prilosec / Prilosec OTC)

Patisiran (Onpattro)

Pergolide (Permax)

Phytonadione (Vitamin K1) (Mephyton / AquaMEPHYTON / Konakion)

Pitavastatin (Livalo / Zypitamag / Nikita)

Propoxyphene (Darvon, Darvocet-N (with paracetamol); co-proxamol in the United Kingdom)

Raloxifene (Evista)

Raltegravir (Isentress and Isentress HD)

Rapacuronium (Raplon)

Sermorelin (Geref, Geref Diagnostic (both discontinued))

Sibutramine (Meridia / Reductil)

Survodutide (BI 456906 (no trade name; not approved))

Tacrolimus (Prograf / Astagraf XL / Envarsus XR / Protopic)

Terfenadine (Seldane / Triludan)

Testosterone enanthate (Delatestryl, Xyosted; also sold as generic testosterone enanthate injection)

Ticagrelor (Brilinta)