Medicine library

Browse medicines, page 3 of 6

Some records contain detailed evidence; others currently contain only basic identity and regulatory information. Reviewed conclusions appear only when they are available for a specific use and group of people.

Showing 121–180 of 357 records

Saxagliptin (Onglyza)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Type 2 diabetes — a tablet that makes the gut hormone signal last longer
Tadalafil (Cialis)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
An enlarged prostate causing a weak stream and frequent urination — and, in the same tablet, erectile dysfunction
Verapamil (Calan / Isoptin / Verelan / Verelan PM / Covera-HS)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Chest pain, a racing or irregular heartbeat, and high blood pressure
Adapalene (Differin / Differin Gel 0.1% (over the counter) / Epiduo (with benzoyl peroxide))
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Acne
Adrafinil (CRL-40028; sold in the United States as a nootropic dietary supplement)
Small chemical medicineDietary supplement; not FDA-approved as a medicineDetailed record
Use listed on the medicine record
A prodrug of modafinil, sold as a supplement because it was never scheduled
Benfluorex (Mediator)
Small chemical medicineWithdrawn from the marketDetailed record
Use listed on the medicine record
A tablet marketed for blood fats and for weight in diabetes, widely prescribed in France
Buprenorphine (Subutex / Suboxone / Butrans / Belbuca / Sublocade)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Opioid use disorder, and severe long-term pain
Calcipotriene (Dovonex / Sorilux / Calcitrene / Taclonex (with betamethasone dipropionate))
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Plaque psoriasis — the raised, red, scaly patches
Cariprazine (Vraylar)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Schizophrenia, both phases of bipolar I disorder, and depression that has not responded to an antidepressant alone
Ceftriaxone (Rocephin)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Serious bacterial infections given by injection — pneumonia, meningitis, bloodstream, bone, urinary and sexually transmitted infection
Cerivastatin (Baycol / Lipobay)
Small chemical medicineWithdrawn from the marketDetailed record
Use listed on the medicine record
A cholesterol-lowering statin
Dexamethasone (Decadron / Dexamethasone Sodium Phosphate / Maxidex / Ozurdex / Hemady)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Severe inflammation and swelling — including brain swelling, croup, some cancers, and COVID-19 severe enough to need oxygen
Diclofenac (Voltaren, Cataflam, Voltaren Arthritis Pain (topical gel), Solaraze)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Arthritis pain and inflammation
Diltiazem (Cardizem / Cardizem CD / Cardizem LA / Tiadylt / Cartia XT)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Chest pain from narrowed or spasming arteries, high blood pressure, and a heart racing out of rhythm
Enoxaparin (Lovenox)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Preventing and treating blood clots in the legs and lungs, and in heart attacks
Epinephrine (EpiPen / Auvi-Q / Adrenalin / neffy)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
A severe allergic reaction — the adrenaline pen
Fentanyl (Sublimaze (injection, NDA 016619, 1968); Duragesic (transdermal patch, NDA 019813, 1990); Actiq (oral transmucosal lozenge, NDA 020747, 1998); Fentora, Subsys, Abstral, Lazanda)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
A hospital anaesthetic and a patch for severe chronic pain. Separately, illicitly manufactured fentanyl is the drug involved in most American overdose deaths, and it is increasingly pressed into counterfeit pills
Glyburide (Diabeta / Micronase / Glynase PresTab (glibenclamide outside the United States))
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Type 2 diabetes — the strongest and longest-acting of the old sulfonylurea tablets
Hydralazine (Apresoline / Dralzine; as a fixed combination with isosorbide dinitrate, BiDil)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
High blood pressure, including when it must be brought down urgently; and, combined with a nitrate, heart failure
Hydroxychloroquine (Plaquenil / Sovuna)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Lupus, rheumatoid arthritis, and malaria where the parasite is still susceptible
Isosorbide Dinitrate (Isordil / Dilatrate-SR / Sorbitrate; as a fixed combination with hydralazine, BiDil)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Preventing angina — chest pain from narrowed heart arteries
Ketoconazole (Nizoral / Nizoral Anti-Dandruff / Extina / Xolegel / Ketoconazole shampoo 2%)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Dandruff and seborrhoeic dermatitis, and the pale or dark patches of tinea versicolor
Levetiracetam (Keppra)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Epilepsy, including focal seizures and generalised seizures
Lidocaine (Xylocaine)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Numbing part of the body for a procedure, and steadying a dangerously fast heart rhythm
Midazolam (Versed; also marketed as midazolam hydrochloride injection and in sodium chloride)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Making a person calm and drowsy for a procedure, and making sure they do not remember it
Naltrexone (ReVia / Vivitrol)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Alcohol use disorder, and relapse prevention in opioid use disorder
Nitazenes (Isotonitazene and the 2-Benzylbenzimidazole Opioids) (None. Never marketed as a medicine anywhere. Sold in the illicit supply as counterfeit tablets, in heroin substitutes and as powder)
Small chemical medicineControlled substance; no approved US useDetailed record
Use listed on the medicine record
Nothing. These are 1950s analgesic candidates that were never developed, resurfacing sixty years later in the illicit drug supply because they are easy to make and are not on the lists
Omeprazole (Prilosec / Prilosec OTC)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Heartburn, acid reflux and stomach or duodenal ulcers
Pergolide (Permax)
Small chemical medicineWithdrawn from the marketDetailed record
Use listed on the medicine record
A Parkinson's disease tablet taken alongside levodopa
Phytonadione (Vitamin K1) (Mephyton / AquaMEPHYTON / Konakion)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Bleeding, or a risk of bleeding, because the body cannot finish building four of its clotting proteins — from warfarin, from a newborn gut that has not started making vitamin K yet, or from a condition that stops fat being absorbed
Pitavastatin (Livalo / Zypitamag / Nikita)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
High cholesterol
Propoxyphene (Darvon, Darvocet-N (with paracetamol); co-proxamol in the United Kingdom)
Small chemical medicineWithdrawn from the marketDetailed record
Use listed on the medicine record
A weak opioid painkiller for mild to moderate pain
Raloxifene (Evista)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Thinning bones after menopause, and lowering the chance of developing one type of breast cancer
Raltegravir (Isentress and Isentress HD)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
HIV-1 infection, as part of a combination regimen
Rapacuronium (Raplon)
Small chemical medicineWithdrawn from the marketDetailed record
Use listed on the medicine record
A fast-acting muscle relaxant given at the start of anaesthesia to allow a breathing tube to be placed
Sibutramine (Meridia / Reductil)
Small chemical medicineWithdrawn from the marketDetailed record
Use listed on the medicine record
A prescription appetite suppressant for obesity
Tacrolimus (Prograf / Astagraf XL / Envarsus XR / Protopic)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Stopping the body rejecting a transplanted organ, and severe eczema that has not responded to steroid creams
Terfenadine (Seldane / Triludan)
Small chemical medicineWithdrawn from the marketDetailed record
Use listed on the medicine record
A hay fever tablet that did not make you drowsy
Testosterone enanthate (Delatestryl, Xyosted; also sold as generic testosterone enanthate injection)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Testosterone replacement for men whose testicles or pituitary do not make enough
Ticagrelor (Brilinta)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Preventing heart attacks, strokes and stent clots after a heart attack or unstable angina
Topiramate (Topamax / Trokendi XR / Qudexy XR)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Epilepsy, including focal and generalised seizures and Lennox-Gastaut syndrome, and prevention of migraine attacks
Trazodone (Desyrel / Oleptro (both discontinued as brands))
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Depression — although most people who are given it are taking it to sleep, which is not a licensed use
Argatroban (Argatroban in 0.9% Sodium Chloride)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Preventing and treating clots in people who have had a dangerous immune reaction to heparin
Aripiprazole (Abilify)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Schizophrenia, bipolar disorder, depression that has not responded to an antidepressant alone, irritability in autism, and Tourette disorder
Azathioprine (Imuran / Azasan)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Stopping the immune system rejecting a transplanted kidney, and severe rheumatoid arthritis that has not responded to other treatment
Beclomethasone (Qvar / Qvar Redihaler / Qnasl / Beconase AQ / Vancenase AQ / Beclovent)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
A daily preventer inhaler for asthma, and a nasal spray for hay fever
Benzonatate (Tessalon)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
A cough, of any cause
Calcitriol (Rocaltrol / Calcijex / Vectical)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Low calcium and overactive parathyroid glands caused by kidney failure, and low calcium caused by absent parathyroid hormone
Chlorpheniramine (Chlor-Trimeton / Allergy Relief)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Sneezing, runny nose and itchy eyes — the old allergy tablet
Clopidogrel (Plavix)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Preventing clots after a heart attack, a stent, a stroke, or in blocked leg arteries
Clozapine (Clozaril, FazaClo, Versacloz)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
The antipsychotic used when others have failed, and the only one shown to reduce suicide risk in schizophrenia
Daclatasvir (Daklinza)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Long-standing hepatitis C infection, genotype 1 or 3
Dalteparin (Fragmin)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Preventing and treating blood clots, including the long-term treatment of clots in people with cancer
Dextromethorphan (Sold over the counter in hundreds of cough products. Prescription combinations: Nuedexta (with quinidine, NDA 021879, 2010) and Auvelity (with bupropion, NDA 215430, 2022))
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
The cough suppressant in most supermarket cough syrups. At many times that dose it is a dissociative, and the same molecule is now half of a prescription antidepressant
Dolutegravir (Tivicay / Tivicay PD)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
HIV-1 infection, as part of a combination regimen
Esketamine (Spravato)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Depression that has not responded to at least two other antidepressants
Fluvastatin (Lescol / Lescol XL)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
High cholesterol, and reducing the chance of needing a stent or a bypass in people who already have coronary disease
Glimepiride (Amaryl)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Type 2 diabetes — the sulfonylurea with the largest outcome trial behind it
Glipizide (Glucotrol / Glucotrol XL)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Type 2 diabetes — a tablet that squeezes more insulin out of the pancreas
Haloperidol (Haldol)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Psychosis, and the tics of Tourette disorder

Saxagliptin (Onglyza)

Tadalafil (Cialis)

Verapamil (Calan / Isoptin / Verelan / Verelan PM / Covera-HS)

Adapalene (Differin / Differin Gel 0.1% (over the counter) / Epiduo (with benzoyl peroxide))

Adrafinil (CRL-40028; sold in the United States as a nootropic dietary supplement)

Benfluorex (Mediator)

Buprenorphine (Subutex / Suboxone / Butrans / Belbuca / Sublocade)

Calcipotriene (Dovonex / Sorilux / Calcitrene / Taclonex (with betamethasone dipropionate))

Cariprazine (Vraylar)

Ceftriaxone (Rocephin)

Cerivastatin (Baycol / Lipobay)

Dexamethasone (Decadron / Dexamethasone Sodium Phosphate / Maxidex / Ozurdex / Hemady)

Diclofenac (Voltaren, Cataflam, Voltaren Arthritis Pain (topical gel), Solaraze)

Diltiazem (Cardizem / Cardizem CD / Cardizem LA / Tiadylt / Cartia XT)

Enoxaparin (Lovenox)

Epinephrine (EpiPen / Auvi-Q / Adrenalin / neffy)

Fentanyl (Sublimaze (injection, NDA 016619, 1968); Duragesic (transdermal patch, NDA 019813, 1990); Actiq (oral transmucosal lozenge, NDA 020747, 1998); Fentora, Subsys, Abstral, Lazanda)

Glyburide (Diabeta / Micronase / Glynase PresTab (glibenclamide outside the United States))

Hydralazine (Apresoline / Dralzine; as a fixed combination with isosorbide dinitrate, BiDil)

Hydroxychloroquine (Plaquenil / Sovuna)

Isosorbide Dinitrate (Isordil / Dilatrate-SR / Sorbitrate; as a fixed combination with hydralazine, BiDil)

Ketoconazole (Nizoral / Nizoral Anti-Dandruff / Extina / Xolegel / Ketoconazole shampoo 2%)

Levetiracetam (Keppra)

Lidocaine (Xylocaine)

Midazolam (Versed; also marketed as midazolam hydrochloride injection and in sodium chloride)

Naltrexone (ReVia / Vivitrol)

Nitazenes (Isotonitazene and the 2-Benzylbenzimidazole Opioids) (None. Never marketed as a medicine anywhere. Sold in the illicit supply as counterfeit tablets, in heroin substitutes and as powder)

Omeprazole (Prilosec / Prilosec OTC)

Pergolide (Permax)

Phytonadione (Vitamin K1) (Mephyton / AquaMEPHYTON / Konakion)

Pitavastatin (Livalo / Zypitamag / Nikita)

Propoxyphene (Darvon, Darvocet-N (with paracetamol); co-proxamol in the United Kingdom)

Raloxifene (Evista)

Raltegravir (Isentress and Isentress HD)

Rapacuronium (Raplon)

Sibutramine (Meridia / Reductil)

Tacrolimus (Prograf / Astagraf XL / Envarsus XR / Protopic)

Terfenadine (Seldane / Triludan)

Testosterone enanthate (Delatestryl, Xyosted; also sold as generic testosterone enanthate injection)

Ticagrelor (Brilinta)

Topiramate (Topamax / Trokendi XR / Qudexy XR)

Trazodone (Desyrel / Oleptro (both discontinued as brands))

Argatroban (Argatroban in 0.9% Sodium Chloride)

Aripiprazole (Abilify)

Azathioprine (Imuran / Azasan)

Beclomethasone (Qvar / Qvar Redihaler / Qnasl / Beconase AQ / Vancenase AQ / Beclovent)

Benzonatate (Tessalon)

Calcitriol (Rocaltrol / Calcijex / Vectical)

Chlorpheniramine (Chlor-Trimeton / Allergy Relief)

Clopidogrel (Plavix)

Clozapine (Clozaril, FazaClo, Versacloz)

Daclatasvir (Daklinza)

Dalteparin (Fragmin)

Dextromethorphan (Sold over the counter in hundreds of cough products. Prescription combinations: Nuedexta (with quinidine, NDA 021879, 2010) and Auvelity (with bupropion, NDA 215430, 2022))

Dolutegravir (Tivicay / Tivicay PD)

Esketamine (Spravato)

Fluvastatin (Lescol / Lescol XL)

Glimepiride (Amaryl)

Glipizide (Glucotrol / Glucotrol XL)

Haloperidol (Haldol)