NR1D1
NR1D1 REV-ERB alpha — the molecular target that 1 compounds in the wiki act on.
In one line: A body-clock gene that, when nudged, tells muscles to build more energy factories.
NR1D1 (REV-ERB alpha) is part of your internal 24-hour clock, and it also controls how many mitochondria (energy factories) your muscles build. The research compound SR9009 activates it, which in mice increased endurance and metabolic rate — an "exercise in a bottle" idea.
The reality check: it's barely absorbed when taken by mouth, so the impressive mouse results probably don't carry over to humans taking it as a pill.