NFE2L2/NRF2
NFE2L2/NRF2 — the molecular target that 1 compounds in the wiki act on.
In one line: The master switch for your body's own antioxidant and detox defences.
NRF2 is a master switch that, when flipped on, turns on around 200 of your body's own antioxidant and detox genes — your built-in defence system against damage. Sulforaphane, from broccoli sprouts, is the best-known natural activator.
The clever part: instead of supplying antioxidants from outside, this switches on your body's own defence factory, which is far more powerful and long-lasting. Broccoli sprouts are the richest source.