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MTNR1A

MTNR1A melatonin receptor 1A — the molecular target that 1 compounds in the wiki act on.

In one line: The receptor for melatonin — your body's "it's night time" signal.

MTNR1A is a receptor for melatonin, the hormone your brain releases in darkness to say "it's night." It doesn't knock you out like a sedative — it re-times your internal body clock. That's why melatonin works best for jet lag and for people whose sleep runs late, rather than as a sledgehammer.

The common mistake is dosing far too high: a tiny amount (0.5 mg) shifts the clock as well as 10 mg, with less next-morning grogginess.

Compounds acting on MTNR1A