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GABBR1

GABBR1 GABA-B receptor — the molecular target that 1 compounds in the wiki act on.

In one line: A slower "calm" receptor — the one phenibut presses (with a dependence risk).

GABBR1 is the GABA-B receptor, a slower-acting version of the brain's main "brake." When activated it produces calm and sociability. Phenibut works here — which is why it reduces anxiety and lowers inhibitions.

The serious catch: pressing this receptor builds tolerance fast, and stopping causes a genuinely nasty withdrawal. It's easy to get into trouble with, so it's a "handle with real caution" compound rather than a casual calming aid.

Compounds acting on GABBR1