COMT
COMT — the molecular target that 1 compounds in the wiki act on.
In one line: An enzyme that clears your "alertness" chemicals — slowing it makes their effect last longer.
COMT breaks down noradrenaline and dopamine, ending their "alert and focused" signal. Green tea's EGCG partly blocks this enzyme, so those signals linger a bit longer — which is why green tea extract has a mild fat-burning and focus effect, especially alongside caffeine.
Interestingly, people naturally vary in how fast their COMT works, which is part of why some handle caffeine and stress very differently from others.