ALOX5
ALOX5 5-lipoxygenase — the molecular target that 1 compounds in the wiki act on.
In one line: An enzyme that makes a specific kind of inflammation — one that ordinary painkillers miss.
ALOX5 (5-lipoxygenase) builds leukotrienes, inflammatory messengers that drive joint pain through a route that common anti-inflammatories (like ibuprofen) don't touch. Boswellia (frankincense extract) blocks this enzyme, which is why it helps joint pain from a different angle and is often stacked with curcumin for broader coverage.
Think of inflammation as coming from several taps — this one shuts a tap the usual drugs leave running.