🧬 RNAwiki
HomeSolveLow Mood / Depression

🌧️ Low Mood / Depression

Low monoamines + inflammation

Persistent low mood, anhedonia, low drive.

⭐ Your one keystone

Move your body daily, and log one small win.

Exercise rivals first-line antidepressants; naming a tiny daily win is the evidence-based behavioural lever. Not a substitute for care.

Move — the mechanics that fix it: Exercise as first-line

Regular aerobic + resistance exercise has antidepressant effect; seek care for persistent symptoms.

Fuel — foods to fuel it

Daily nutrient targets: omega3: 2000mg (goal), choline: 500mg (goal), fiber: 30g (goal), sugar: 30g (limit)

Stack — evidence-ranked compounds

Open the Fuel Tracker for this protocol →

Educational protocol, not medical advice.

Common questions

What causes low mood / depression?

Low monoamines + inflammation. Persistent low mood, anhedonia, low drive.

What exercises help low mood / depression?

Key movements: Air Bike, Cross-Body Crunch, Decline Oblique Crunch, Bodyweight Squat.

What should you eat for low mood / depression?

Foods that support it: Salmon (cooked), Kiwi fruit, Sardines (canned in water), Blueberries, Tuna (canned in water).

What supplements help low mood / depression?

Evidence-ranked options: Omega-3 (EPA/DHA), Saffron (Crocus sativus), 5-HTP / L-Tryptophan, Vitamin D3 (+ K2), SSRIs (Sertraline, Escitalopram).