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HomeWOMEN'S HEALTH & FEMALE HORMONESMyo-Inositol (+ D-Chiro)

Myo-Inositol (+ D-Chiro)

Evidence: ★★★★☆ · Status: OTC Supplement

💡 Did you know? Myo-inositol improves insulin signalling in PCOS — and the body wants it in a specific 40-to-1 ratio with its cousin, D-chiro-inositol.

In plain English

Improves how ovaries respond to insulin — one of the best-evidenced natural treatments for PCOS (irregular cycles, acne, unwanted hair).

How it works

Insulin second-messenger; the 40:1 myo:D-chiro ratio improves ovarian insulin signalling, restoring ovulation and lowering androgens in PCOS.

Molecular target & official sources

Myo-inositol (PubChem CID 892) · Examine: inositol

Protocol

2–4 g myo-inositol/day. **Bottom line:** First-line natural PCOS support.

Helps with: Hormones & Testosterone · Skin & Hair

Stacks with

Shares a pathway — often paired with: Omega-3 (EPA/DHA), Vitamin D3 (+ K2), Testosterone (TRT), Finasteride / Dutasteride.

Availability & where to buy

Available over the counter. Widely available OTC — e.g. iHerb (ships worldwide); in Singapore also Guardian, Watsons, GNC, Shopee / Lazada. Look for a third-party-tested / GMP mark and check the dose per serving.

How it works: the Nuclear receptors pathway →

Used in these protocols

Compare Myo-Inositol (+ D-Chiro)

Common questions

Does Myo-Inositol (+ D-Chiro) actually work?

Human-evidence rating: 4 of 5. Improves how ovaries respond to insulin — one of the best-evidenced natural treatments for PCOS (irregular cycles, acne, unwanted hair).

How do you take Myo-Inositol (+ D-Chiro)?

2–4 g myo-inositol/day. Bottom line: First-line natural PCOS support.

Is Myo-Inositol (+ D-Chiro) legal or approved?

Regulatory status: OTC Supplement.