Myo-Inositol (+ D-Chiro)
Evidence: ★★★★☆ · Status: OTC Supplement
In plain English
Improves how ovaries respond to insulin — one of the best-evidenced natural treatments for PCOS (irregular cycles, acne, unwanted hair).
How it works
Insulin second-messenger; the 40:1 myo:D-chiro ratio improves ovarian insulin signalling, restoring ovulation and lowering androgens in PCOS.
Molecular target & official sources
Myo-inositol (PubChem CID 892) · Examine: inositol
Protocol
2–4 g myo-inositol/day. **Bottom line:** First-line natural PCOS support.
Helps with: Hormones & Testosterone · Skin & Hair
Stacks with
Shares a pathway — often paired with: Omega-3 (EPA/DHA), Vitamin D3 (+ K2), Testosterone (TRT), Finasteride / Dutasteride.
Availability & where to buy
Available over the counter. Widely available OTC — e.g. iHerb (ships worldwide); in Singapore also Guardian, Watsons, GNC, Shopee / Lazada. Look for a third-party-tested / GMP mark and check the dose per serving.
How it works: the Nuclear receptors pathway →
Used in these protocols
Compare Myo-Inositol (+ D-Chiro)
- Myo-Inositol (+ D-Chiro) vs Vitamin D3 (+ K2)
- Myo-Inositol (+ D-Chiro) vs Finasteride / Dutasteride
- Myo-Inositol (+ D-Chiro) vs Tretinoin / Retinoids
- Myo-Inositol (+ D-Chiro) vs Minoxidil
- Myo-Inositol (+ D-Chiro) vs Human Growth Hormone (Somatropin)
- Myo-Inositol (+ D-Chiro) vs Collagen Peptides (+ Vitamin C)
- Myo-Inositol (+ D-Chiro) vs Vitamin C (Ascorbate)
Common questions
Does Myo-Inositol (+ D-Chiro) actually work?
Human-evidence rating: 4 of 5. Improves how ovaries respond to insulin — one of the best-evidenced natural treatments for PCOS (irregular cycles, acne, unwanted hair).
How do you take Myo-Inositol (+ D-Chiro)?
2–4 g myo-inositol/day. Bottom line: First-line natural PCOS support.
Is Myo-Inositol (+ D-Chiro) legal or approved?
Regulatory status: OTC Supplement.