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Fadogia Agrestis

Evidence: ★☆☆☆☆ · Status: OTC Supplement

💡 Did you know? Fadogia agrestis, a West African shrub touted for testosterone, is backed mostly by rodent studies — with real toxicity red flags.

In plain English

Podcast-famous, but there are zero human studies and the rat studies show it can damage the testicles. Zinc, D3, boron and tongkat do the same job with real human data and no toxicity signal.

How it works

Proposed LH-mimetic/Leydig-cell stimulation — but only in rodents, where the same studies also show dose-dependent testicular toxicity.

Molecular target & official sources

Examine: Fadogia agrestis

Bottom line

Avoid until human safety data exists.

Helps with: Hormones & Testosterone

Stacks with

Shares a pathway — often paired with: Omega-3 (EPA/DHA), Vitamin D3 (+ K2), Testosterone (TRT), Finasteride / Dutasteride.

Availability & where to buy

Available over the counter. Widely available OTC — e.g. iHerb (ships worldwide); in Singapore also Guardian, Watsons, GNC, Shopee / Lazada. Look for a third-party-tested / GMP mark and check the dose per serving.

How it works: the Nuclear receptors pathway →

Common questions

Does Fadogia Agrestis actually work?

Human-evidence rating: 1 of 5. Avoid until human safety data exists.

Is Fadogia Agrestis legal or approved?

Regulatory status: OTC Supplement.