Medicine library

Browse medicines, page 6 of 8

Some records contain detailed evidence; others currently contain only basic identity and regulatory information. Reviewed conclusions appear only when they are available for a specific use and group of people.

Showing 301–360 of 475 records

Bupivacaine (Marcaine, Sensorcaine, Sensorcaine MPF; liposomal formulation marketed as Exparel)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Numbing an area of the body for hours rather than for an hour, for surgery, childbirth or a nerve block
Cangrelor (Kengreal)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Preventing clots during a stent procedure in someone who has not already taken a platelet tablet
Carbamazepine (Tegretol / Carbatrol / Equetro)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Focal and generalised epilepsy, trigeminal nerve pain, and mania in bipolar I disorder
Casimersen (Amondys 45)
Gene-silencing medicineFDA accelerated approval (based on an earlier result expected to predict benefit; follow-up evidence may be required)Detailed record
Use listed on the medicine record
Duchenne Muscular Dystrophy (exon 45 skipping)
CJC-1295 (CJC-1295 with DAC. The product sold as "CJC-1295 without DAC" is a different molecule, modified GRF(1-29))
Peptide medicineIn Phase 2 testingDetailed record
Use listed on the medicine record
Raises growth hormone for a week per injection — no approved use anywhere
Clenbuterol (Ventipulmin (veterinary, United States); Spiropent, Broncoterol and others abroad)
Small chemical medicineControlled substance; no approved US useDetailed record
Use listed on the medicine record
A horse asthma drug in the United States, taken by people for fat loss
Clobazam (Onfi / Sympazan)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Drop attacks and other seizures in Lennox-Gastaut syndrome, added to other seizure medicines
Daptomycin (Cubicin)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Serious skin infections and bloodstream infections caused by resistant Gram-positive bacteria — not lung infections, which it cannot treat
Delta-8-Tetrahydrocannabinol (No approved product. Sold as vape cartridges, gummies, tinctures and pre-rolls in petrol stations, smoke shops and online)
Small chemical medicineControlled substance; no approved US useDetailed record
Use listed on the medicine record
Nothing approved. It is a legal-in-most-states intoxicant made by chemically converting CBD, and children under six accounted for 30.1% of the poison-centre cases
Donanemab (Kisunla)
Antibody medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Early Alzheimer disease, with treatment stopped once the plaque is cleared
Doxycycline (Vibramycin / Oracea / Doryx)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Tick-borne and sexually transmitted infections, chest infections, acne, and malaria prevention
Efalizumab (Raptiva)
Antibody medicineWithdrawn from the marketDetailed record
Use listed on the medicine record
A weekly injection for severe plaque psoriasis
Fenfluramine (Fintepla (2020); formerly Pondimin, and half of "fen-phen")
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Seizures in two severe childhood epilepsies — the same molecule that was once a diet pill
Idarucizumab (Praxbind)
Antibody medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Switching off the blood thinner dabigatran in an emergency — a serious bleed, or an operation that cannot wait
Ipratropium (Atrovent / Atrovent HFA / Ipratropium Bromide Inhalation Solution)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
A short-acting inhaler or nebuliser that blocks the nerve signal tightening the airway, and a nasal spray for a running nose
Loperamide (Imodium / Imodium A-D)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Diarrhoea — slowing the bowel down so stools become less frequent and more solid
LSA (Ergine) — Morning Glory and Hawaiian Baby Woodrose Seeds (No product. The seeds are sold as garden seed under cultivar names such as Heavenly Blue and Pearly Gates, and as Argyreia nervosa seed)
Nutritional or plant productDietary supplement; not FDA-approved as a medicineDetailed record
Use listed on the medicine record
Nothing. These are garden seeds containing an ergot alkaloid, sold in every seed rack, and the compound in them is not federally controlled
Mescaline (No marketed product. The principal alkaloid of peyote (Lophophora williamsii) and San Pedro (Trichocereus / Echinopsis species))
Small chemical medicineControlled substance; no approved US useDetailed record
Use listed on the medicine record
Nothing. Mescaline is the only classic psychedelic in this group with no modern randomised trial at all
Methadone (Methadose / Dolophine / Methadone Hydrochloride Intensol)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Opioid dependence, as maintenance or detoxification treatment; and severe long-term pain
Nateglinide (Starlix)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Type 2 diabetes — the fastest and weakest of the meal-time tablets
Onasemnogene abeparvovec (Zolgensma)
Gene-editing or gene therapyApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Spinal muscular atrophy in babies under two
PCP (Phencyclidine) (Sernyl — marketed by Parke-Davis as a human anaesthetic from the late 1950s and withdrawn from human use in the mid-1960s; Sernylan, the veterinary formulation, was withdrawn in 1978)
Small chemical medicineControlled substance; no approved US useDetailed record
Use listed on the medicine record
Nothing. It was an anaesthetic that worked but left patients delirious for hours afterwards, and it became the drug that taught psychiatry what schizophrenia might be a disorder of
Phenylpiracetam (Phenotropil, Actitropil; also called fonturacetam and carphedon)
Small chemical medicineDietary supplement; not FDA-approved as a medicineDetailed record
Use listed on the medicine record
A Russian prescription nootropic sold in the West as a supplement, banned in sport since 1998
Phenylpropanolamine (Dexatrim, Acutrim (appetite suppressants); Triaminic, Dimetapp, Contac (decongestants))
Small chemical medicineWithdrawn from the marketDetailed record
Use listed on the medicine record
A decongestant and over-the-counter diet pill, sold without prescription for decades
Psyllium husk (Sold as ispaghula husk; the dominant branded product is Metamucil)
Nutritional or plant productDietary supplement; not FDA-approved as a medicineDetailed record
Use listed on the medicine record
Taken for constipation and regularity, and to lower cholesterol
Romiplostim (Nplate)
Protein medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
A weekly injection that tells the bone marrow to make more platelets — and, separately, the drug stockpiled to keep people alive after a radiation accident
Saffron extract (Sold as affron, Safr'Inside and other standardised Crocus sativus stigma extracts)
Nutritional or plant productDietary supplement; not FDA-approved as a medicineDetailed record
Use listed on the medicine record
Marketed for mood and anxiety
Selank (Selank; the peptide is written Thr-Lys-Pro-Arg-Pro-Gly-Pro)
Peptide medicineDietary supplement; not FDA-approved as a medicineDetailed record
Use listed on the medicine record
A Russian anti-anxiety peptide, sold elsewhere as a nasal spray research chemical
Sitagliptin (Januvia)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Type 2 diabetes
Sulfasalazine (Azulfidine / Azulfidine EN-tabs / Salazopyrin)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Ulcerative colitis and rheumatoid arthritis
TB-500 (thymosin beta-4) (Sold as TB-500. The full peptide is thymosin beta-4, developed as RGN-259 (eye drops) and NL005 (recombinant injection))
Peptide medicineIn Phase 3 testingDetailed record
Use listed on the medicine record
Sold for injury repair — nothing containing it is approved anywhere
Tenofovir Disoproxil (Viread; also the tenofovir component of Truvada and Atripla)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
HIV-1 infection, HIV prevention, and chronic hepatitis B
Terbinafine (Lamisil / Lamisil AT (topical, over the counter))
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Fungal nail infection, athlete’s foot and ringworm
Testolone (RAD140; sold online as testolone)
Small chemical medicineLaboratory or animal-stage researchDetailed record
Use listed on the medicine record
Nothing, in humans. Its human evidence is one 20-person cancer dose-finding study
Thioridazine (Mellaril, Mellaril-S)
Small chemical medicineWithdrawn from the marketDetailed record
Use listed on the medicine record
An older antipsychotic tablet, restricted and then effectively withdrawn over heart rhythm risk
Trenbolone (Approved in the United States only for cattle, as trenbolone acetate implants (Finaplix, and in combination products such as Revalor and Synovex Plus))
Small chemical medicineControlled substance; no approved US useDetailed record
Use listed on the medicine record
None in people. It is a cattle growth implant and a controlled substance
Valdecoxib (Bextra)
Small chemical medicineWithdrawn from the marketDetailed record
Use listed on the medicine record
An arthritis and period-pain tablet designed to spare the stomach
Venlafaxine (Effexor / Effexor XR)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Depression; the extended-release form is also used for several anxiety disorders
Volanesorsen (Waylivra)
Gene-silencing medicineApproved in the European Union (EMA)Detailed record
Use listed on the medicine record
Familial Chylomicronaemia Syndrome (very high triglycerides)
Vutrisiran (Amvuttra)
RNA-silencing medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Transthyretin amyloidosis affecting the nerves or the heart
Zoledronic Acid (Zometa / Reclast)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Fragile bones, and the bone damage caused by some cancers — two different products with the same active drug
Amisulpride (Barhemsys)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
In America, sickness after an operation. Everywhere else, schizophrenia.
Amoxicillin and Clavulanate Potassium (Augmentin)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Bacterial infections of the ear, sinuses, chest, skin and urinary tract
Azelastine (Astelin / Astepro / Astepro Allergy)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Hay fever, and the non-allergic runny nose that weather, smells and temperature set off
Brivaracetam (Briviact)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Focal (partial-onset) epilepsy
Buspirone (BuSpar / Bucapsol — both discontinued as brands)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Anxiety
Cinacalcet (Sensipar)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Overactive parathyroid glands, mainly in people on dialysis, and high blood calcium caused by a parathyroid tumour
Collagen peptides (Sold as hydrolysed collagen, collagen hydrolysate, gelatin hydrolysate or "specific collagen peptides"; brand ingredients include Verisol, Fortigel and CH-Alpha)
Nutritional or plant productDietary supplement; not FDA-approved as a medicineDetailed record
Use listed on the medicine record
Taken for skin, joints, hair and nails
Digoxin (Lanoxin / Lanoxin Pediatric / Lanoxicaps)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Heart failure symptoms, and slowing a fast resting pulse in long-standing atrial fibrillation
Entecavir (Baraclude)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Long-standing hepatitis B infection of the liver
Ethosuximide (Zarontin)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Absence seizures, the brief blank spells of childhood absence epilepsy
Furosemide (Lasix)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Fluid overload from heart, liver or kidney disease
Grazoprevir (Zepatier)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Long-standing hepatitis C infection, genotype 1 or 4 only
Isotretinoin (Accutane, Roaccutane, Absorica, Claravis, Amnesteem, Myorisan)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
A course of capsules for severe acne, available only through a registration programme because of birth defects
Levalbuterol (Xopenex / Xopenex HFA)
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
A tight chest and wheeze — the purified half of the blue inhaler
Mephedrone (4-Methylmethcathinone) (Sold openly in the United Kingdom in 2009 and 2010 as "plant food" and "bath salts", labelled not for human consumption. No approved product)
Small chemical medicineControlled substance; no approved US useDetailed record
Use listed on the medicine record
Nothing. It was sold legally across the UK for about eighteen months, banned in 2010, and is now the best-studied of the synthetic cathinones
Oxymetazoline (Afrin (nasal spray) / Rhofade (1% cream) / Upneeq (0.1% eye drops))
Small chemical medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
A blocked nose; the fixed facial redness of rosacea; a drooping upper eyelid
Pegfilgrastim (Neulasta)
Protein medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
One injection per chemotherapy cycle instead of a daily white cell injection
Protamine Sulfate
Protein medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Switching off heparin when someone has had too much of it, or when the operation using it has finished
Ranibizumab (Lucentis)
Antibody medicineApproved in the United States (FDA)Detailed record
Use listed on the medicine record
Leaking abnormal blood vessels growing under the centre of the retina

Bupivacaine (Marcaine, Sensorcaine, Sensorcaine MPF; liposomal formulation marketed as Exparel)

Cangrelor (Kengreal)

Carbamazepine (Tegretol / Carbatrol / Equetro)

Casimersen (Amondys 45)

CJC-1295 (CJC-1295 with DAC. The product sold as "CJC-1295 without DAC" is a different molecule, modified GRF(1-29))

Clenbuterol (Ventipulmin (veterinary, United States); Spiropent, Broncoterol and others abroad)

Clobazam (Onfi / Sympazan)

Daptomycin (Cubicin)

Delta-8-Tetrahydrocannabinol (No approved product. Sold as vape cartridges, gummies, tinctures and pre-rolls in petrol stations, smoke shops and online)

Donanemab (Kisunla)

Doxycycline (Vibramycin / Oracea / Doryx)

Efalizumab (Raptiva)

Fenfluramine (Fintepla (2020); formerly Pondimin, and half of "fen-phen")

Idarucizumab (Praxbind)

Ipratropium (Atrovent / Atrovent HFA / Ipratropium Bromide Inhalation Solution)

Loperamide (Imodium / Imodium A-D)

LSA (Ergine) — Morning Glory and Hawaiian Baby Woodrose Seeds (No product. The seeds are sold as garden seed under cultivar names such as Heavenly Blue and Pearly Gates, and as Argyreia nervosa seed)

Mescaline (No marketed product. The principal alkaloid of peyote (Lophophora williamsii) and San Pedro (Trichocereus / Echinopsis species))

Methadone (Methadose / Dolophine / Methadone Hydrochloride Intensol)

Nateglinide (Starlix)

Onasemnogene abeparvovec (Zolgensma)

PCP (Phencyclidine) (Sernyl — marketed by Parke-Davis as a human anaesthetic from the late 1950s and withdrawn from human use in the mid-1960s; Sernylan, the veterinary formulation, was withdrawn in 1978)

Phenylpiracetam (Phenotropil, Actitropil; also called fonturacetam and carphedon)

Phenylpropanolamine (Dexatrim, Acutrim (appetite suppressants); Triaminic, Dimetapp, Contac (decongestants))

Psyllium husk (Sold as ispaghula husk; the dominant branded product is Metamucil)

Romiplostim (Nplate)

Saffron extract (Sold as affron, Safr'Inside and other standardised Crocus sativus stigma extracts)

Selank (Selank; the peptide is written Thr-Lys-Pro-Arg-Pro-Gly-Pro)

Sitagliptin (Januvia)

Sulfasalazine (Azulfidine / Azulfidine EN-tabs / Salazopyrin)

TB-500 (thymosin beta-4) (Sold as TB-500. The full peptide is thymosin beta-4, developed as RGN-259 (eye drops) and NL005 (recombinant injection))

Tenofovir Disoproxil (Viread; also the tenofovir component of Truvada and Atripla)

Terbinafine (Lamisil / Lamisil AT (topical, over the counter))

Testolone (RAD140; sold online as testolone)

Thioridazine (Mellaril, Mellaril-S)

Trenbolone (Approved in the United States only for cattle, as trenbolone acetate implants (Finaplix, and in combination products such as Revalor and Synovex Plus))

Valdecoxib (Bextra)

Venlafaxine (Effexor / Effexor XR)

Volanesorsen (Waylivra)

Vutrisiran (Amvuttra)

Zoledronic Acid (Zometa / Reclast)

Amisulpride (Barhemsys)

Amoxicillin and Clavulanate Potassium (Augmentin)

Azelastine (Astelin / Astepro / Astepro Allergy)

Brivaracetam (Briviact)

Buspirone (BuSpar / Bucapsol — both discontinued as brands)

Cinacalcet (Sensipar)

Collagen peptides (Sold as hydrolysed collagen, collagen hydrolysate, gelatin hydrolysate or "specific collagen peptides"; brand ingredients include Verisol, Fortigel and CH-Alpha)

Digoxin (Lanoxin / Lanoxin Pediatric / Lanoxicaps)

Entecavir (Baraclude)

Ethosuximide (Zarontin)

Furosemide (Lasix)

Grazoprevir (Zepatier)

Isotretinoin (Accutane, Roaccutane, Absorica, Claravis, Amnesteem, Myorisan)

Levalbuterol (Xopenex / Xopenex HFA)

Mephedrone (4-Methylmethcathinone) (Sold openly in the United Kingdom in 2009 and 2010 as "plant food" and "bath salts", labelled not for human consumption. No approved product)

Oxymetazoline (Afrin (nasal spray) / Rhofade (1% cream) / Upneeq (0.1% eye drops))

Pegfilgrastim (Neulasta)

Protamine Sulfate

Ranibizumab (Lucentis)