:root {
  color-scheme: light;
  --ink: #20232a;
  --muted: #60656f;
  --quiet: #7b8088;
  --blue: #176fe5;
  --blue-dark: #1258b5;
  --blue-pale: #eaf2ff;
  --line: #dfe2e7;
  --line-strong: #cdd2da;
  --canvas: #ffffff;
  --wash: #f3f4f6;
  --wash-blue: #f1f6ff;
  --caution: #785a17;
  --caution-bg: #fff8e9;
  --serif: "Playfair Display", Georgia, "Times New Roman", serif;
  --sans: "DM Sans", -apple-system, BlinkMacSystemFont, "Segoe UI", sans-serif;
  font-family: var(--sans);
  font-size: 16px;
  color: var(--ink);
  background: var(--canvas);
  font-synthesis: none;
  text-rendering: optimizeLegibility;
}

* { box-sizing: border-box; }
html { scroll-behavior: smooth; scroll-padding-top: 24px; }
body { margin: 0; min-width: 320px; background: var(--canvas); line-height: 1.62; }
a { color: var(--blue-dark); text-decoration-thickness: 1px; text-underline-offset: 3px; }
a:hover { color: #0b448e; }
button, input { font: inherit; }
button { color: inherit; }
::selection { background: #d9e8ff; }

.skip-link, .sr-only { position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0; }
.skip-link:focus { z-index: 100; top: 8px; left: 8px; width: auto; height: auto; clip: auto; margin: 0; padding: 12px 16px; background: #fff; border: 2px solid var(--blue); border-radius: 6px; }
:focus-visible { outline: 3px solid #155ec4; outline-offset: 3px; }

.site-header { width: 100%; display: flex; align-items: center; gap: clamp(20px, 3.4vw, 54px); padding: 17px clamp(20px, 5vw, 76px); border-bottom: 1px solid #eceef1; background: #fff; }
.brand { flex: 0 0 auto; color: var(--ink); font-weight: 700; font-size: 24px; letter-spacing: -1.3px; text-decoration: none; line-height: 1; }
.brand span { color: var(--blue); }
.brand:hover { color: var(--ink); }
.primary-nav { display: flex; align-items: center; gap: clamp(17px, 2.5vw, 38px); flex: 1; }
.primary-nav a { color: #4c5159; font-size: 14px; font-weight: 500; text-decoration: none; white-space: nowrap; }
.primary-nav a:hover { color: var(--blue-dark); }
.header-search, .hero-search { display: flex; align-items: center; gap: 10px; border: 1px solid var(--line-strong); border-radius: 999px; background: #fff; }
.header-search { min-width: 280px; width: min(34vw, 430px); padding: 5px 6px 5px 14px; }
.search-icon { color: #707680; font-size: 24px; line-height: 1; transform: rotate(-18deg); }
.header-search input, .hero-search input { min-width: 0; flex: 1; padding: 7px 0; border: 0; outline: 0; color: var(--ink); background: transparent; font-size: 14px; }
.header-search input::placeholder, .hero-search input::placeholder { color: #777d87; opacity: 1; }
.header-search input:focus-visible, .hero-search input:focus-visible { outline: none; }
.search-submit { border: 0; border-radius: 999px; padding: 8px 14px; color: #fff; background: var(--blue); font-weight: 600; font-size: 13px; cursor: pointer; }
.search-submit:hover, .hero-search button:hover { background: var(--blue-dark); }

#main-content { min-height: 55vh; outline: 0; }
.section-wrap { width: min(1220px, calc(100% - 64px)); margin-inline: auto; }
.eyebrow { margin: 0 0 12px; color: #606774; font-size: 11px; line-height: 1.4; letter-spacing: .13em; font-weight: 700; }
h1, h2, h3, p { margin-top: 0; }
h1, h2 { color: var(--ink); font-family: var(--serif); font-weight: 500; letter-spacing: -.035em; line-height: 1.14; }
h1 em, h2 em { color: var(--blue); font-style: normal; }
h1 { font-size: clamp(42px, 5.5vw, 72px); }
h2 { font-size: clamp(29px, 3vw, 42px); }
h3 { font-size: 19px; line-height: 1.35; }
p { max-width: 72ch; }
.small-note { color: var(--muted); font-size: 14px; line-height: 1.55; }
.text-link { display: inline-flex; align-items: center; gap: 8px; color: var(--blue-dark); font-size: 14px; font-weight: 600; text-decoration: none; }
.text-link:hover { text-decoration: underline; text-underline-offset: 4px; }
.button-outline { display: inline-flex; align-items: center; justify-content: center; gap: 12px; min-height: 48px; padding: 10px 17px; border: 1px solid #aeb9ca; border-radius: 7px; color: #17395f; background: #fff; font-size: 14px; font-weight: 600; text-decoration: none; }
.button-outline:hover { border-color: var(--blue); color: var(--blue-dark); }

.home-hero { display: grid; grid-template-columns: minmax(0, 1fr) 220px; gap: 40px; align-items: center; min-height: 430px; margin: 22px clamp(16px, 2.3vw, 34px) 0; padding: 62px clamp(26px, 8vw, 126px); background: var(--wash); }
.hero-copy { max-width: 840px; margin-inline: auto; text-align: center; }
.hero-copy h1 { margin: 0 auto 20px; font-size: clamp(42px, 5.3vw, 69px); }
.hero-deck { max-width: 640px; margin: 0 auto 26px; color: #535963; font-size: 18px; }
.hero-search { max-width: 720px; margin: 0 auto; padding: 8px 9px 8px 19px; border: 2px solid #4c8cee; box-shadow: 0 2px 12px rgb(23 111 229 / 8%); text-align: left; }
.hero-search .search-icon { font-size: 26px; }
.hero-search input { font-size: 16px; }
.hero-search button { min-height: 44px; padding: 9px 20px; border: 0; border-radius: 999px; color: #fff; background: var(--blue); font-size: 14px; font-weight: 600; cursor: pointer; }
.search-scope { margin: 11px auto 0; color: #686e78; font-size: 13px; }
.hero-aside { align-self: stretch; display: flex; flex-direction: column; justify-content: center; padding-left: 30px; border-left: 1px solid #d4d8de; }
.aside-mark { display: flex; align-items: center; gap: 5px; margin-bottom: 16px; color: var(--blue); font-family: var(--serif); font-size: 44px; }
.aside-mark span { font-family: var(--sans); font-size: 20px; }
.hero-aside p { color: #353a42; font-family: var(--serif); font-size: 21px; line-height: 1.4; }
.aside-footnote { color: #6a7079; font-size: 12px; }
.home-featured { padding-top: 76px; padding-bottom: 72px; }
.section-heading-line { display: flex; align-items: end; justify-content: space-between; gap: 30px; margin-bottom: 24px; }
.section-heading-line h2 { margin-bottom: 0; }
.catalog-grid { display: grid; grid-template-columns: repeat(2, minmax(0, 1fr)); column-gap: 28px; }
.catalog-card { position: relative; min-width: 0; padding: 25px 5px 27px; border-top: 1px solid var(--line-strong); }
.catalog-card[hidden] { display: none !important; }
.card-topline { display: flex; align-items: center; justify-content: space-between; color: #6a7079; font-size: 12px; }
.card-arrow { color: var(--blue); font-size: 18px; }
.catalog-card h3 { margin: 12px 0 3px; font-family: var(--serif); font-size: 28px; font-weight: 500; letter-spacing: -.02em; }
.catalog-card h3 a { color: var(--ink); text-decoration: none; }
.catalog-card h3 a:hover { color: var(--blue-dark); }
.card-subtitle { margin-bottom: 12px; color: #60656f; font-size: 14px; }
.catalog-card > p:not(.card-subtitle) { margin-bottom: 15px; color: #383d45; font-size: 15px; line-height: 1.6; }
.tag-row { display: flex; flex-wrap: wrap; gap: 7px; margin: 14px 0; }
.tag { display: inline-flex; align-items: center; min-height: 27px; padding: 4px 9px; border: 1px solid #d7dce5; border-radius: 999px; color: #4e5662; background: #fff; font-size: 11px; line-height: 1.3; }

.home-note { display: grid; grid-template-columns: 1.2fr 1fr auto; gap: 36px; align-items: center; padding-top: 35px; padding-bottom: 38px; border-top: 1px solid var(--line); }
.home-note h2 { margin-bottom: 0; font-size: clamp(25px, 2.4vw, 34px); }
.home-note > p { margin: 0; color: #505660; }
.landscape-teaser { padding: 51px 0; background: var(--wash-blue); border-top: 1px solid #e4ebf6; }
.teaser-inner { display: flex; align-items: center; justify-content: space-between; gap: 42px; }
.teaser-inner h2 { margin-bottom: 10px; font-size: clamp(29px, 3.2vw, 42px); }
.teaser-inner p:not(.eyebrow) { margin-bottom: 0; color: #515965; }

.page-intro { padding-top: 68px; padding-bottom: 45px; }
.page-intro h1 { margin-bottom: 18px; }
.page-intro > p:not(.eyebrow) { max-width: 720px; color: #4f555e; font-size: 18px; }
.library-section { padding-bottom: 88px; }
.filter-bar { display: flex; flex-wrap: wrap; gap: 8px; margin-bottom: 32px; }
.filter-bar button { min-height: 40px; padding: 8px 14px; border: 1px solid var(--line-strong); border-radius: 999px; color: #4d535d; background: #fff; font-size: 13px; cursor: pointer; }
.filter-bar button[aria-pressed="true"] { border-color: #1966d3; color: #fff; background: #1966d3; }
.empty-state { padding: 36px 0 56px; border-top: 1px solid var(--line); }
.empty-state h2 { font-size: 31px; }

.dossier-headband { margin: 18px clamp(16px, 2.3vw, 34px) 0; background: var(--wash); }
.dossier-heading { padding-top: 28px; padding-bottom: 43px; }
.breadcrumb { display: inline-block; margin-bottom: 29px; color: #4f5864; font-size: 13px; text-decoration: none; }
.breadcrumb:hover { color: var(--blue-dark); text-decoration: underline; }
.dossier-heading h1 { margin: 7px 0 4px; font-size: clamp(54px, 7vw, 86px); }
.dossier-subtitle { margin-bottom: 10px; color: #4f5660; font-family: var(--serif); font-size: clamp(19px, 2vw, 25px); }
.dossier-heading .tag-row { margin-bottom: 20px; }
.source-snapshot { max-width: 830px; margin-bottom: 0; padding-left: 14px; border-left: 2px solid var(--blue); color: #505761; font-size: 14px; }
.dossier-layout { display: grid; grid-template-columns: 200px minmax(0, 800px); justify-content: center; gap: clamp(36px, 6vw, 94px); padding-top: 45px; padding-bottom: 80px; }
.section-index { align-self: start; position: sticky; top: 24px; padding-top: 12px; }
.section-index nav { display: grid; gap: 4px; }
.section-index nav a { padding: 7px 9px; border-left: 2px solid transparent; color: #565d67; font-size: 13px; text-decoration: none; }
.section-index nav a:hover, .section-index nav a:focus-visible { border-left-color: var(--blue); color: var(--blue-dark); background: #f5f8fd; }
.dossier-content { min-width: 0; }
.dossier-section { padding: 43px 0 46px; border-top: 1px solid var(--line); scroll-margin-top: 20px; }
.dossier-section:first-child { padding-top: 0; border-top: 0; }
.section-title { margin-bottom: 18px; }
.section-title .eyebrow { margin-bottom: 8px; }
.section-title h2 { margin-bottom: 0; font-size: clamp(31px, 3.3vw, 42px); }
.dossier-content p { color: #41464f; }
.lede { margin-bottom: 24px; color: #272c33 !important; font-size: 20px; line-height: 1.62; }
.boundary-row { display: grid; grid-template-columns: 135px 1fr; gap: 20px; padding: 16px 0 17px; border-top: 1px solid #e5e7eb; border-bottom: 1px solid #e5e7eb; }
.boundary-label { color: #525862; font-size: 12px; font-weight: 700; letter-spacing: .04em; text-transform: uppercase; }
.boundary-row p { margin: 0; color: #484e57; font-size: 14px; }
.fact-strip { display: grid; grid-template-columns: 1fr 1fr; gap: 22px; padding-top: 18px; }
.fact-strip div { display: grid; gap: 3px; }
.fact-strip span { color: #6e747d; font-size: 12px; }
.fact-strip strong { font-size: 14px; font-weight: 600; }
.safety-callout { display: grid; grid-template-columns: 33px 1fr; gap: 15px; padding: 18px; border-left: 3px solid #b78520; background: var(--caution-bg); }
.callout-mark { display: grid; place-items: center; width: 27px; height: 27px; border: 1.5px solid #9d741f; border-radius: 50%; color: #785a17; font-weight: 700; }
.safety-callout h3 { margin: 0 0 6px; color: #53421d; font-family: var(--sans); font-size: 15px; }
.safety-callout p { margin-bottom: 0; color: #514932; font-size: 15px; }
.plain-list, .alternative-list { display: grid; gap: 12px; padding-left: 22px; color: #41464f; }
.plain-list { margin: 18px 0; }
.plain-list li, .alternative-list li { padding-left: 4px; }
.mechanism-flow { margin: 25px 0 20px; border-left: 2px solid #cbdcf5; }
.mechanism-step { position: relative; display: grid; grid-template-columns: 38px 1fr; gap: 14px; padding: 0 0 21px 18px; }
.mechanism-step:last-child { padding-bottom: 0; }
.mechanism-step::before { content: ""; position: absolute; top: 8px; left: -6px; width: 10px; height: 10px; border-radius: 50%; background: var(--blue); }
.step-number { color: var(--blue-dark); font-size: 12px; font-weight: 700; }
.mechanism-step h3 { margin: 0 0 3px; font-size: 16px; }
.mechanism-step p { margin-bottom: 0; font-size: 15px; }
.expert-detail { margin-top: 22px; border-top: 1px solid var(--line); border-bottom: 1px solid var(--line); }
.expert-detail summary { min-height: 48px; padding: 13px 2px; color: var(--blue-dark); font-size: 14px; font-weight: 600; cursor: pointer; }
.expert-detail p { margin: 0; padding: 0 3px 17px; font-size: 14px; }
.section-intro { margin-bottom: 25px; color: #5c626c !important; font-size: 15px; }
.evidence-card { padding: 21px 0 23px; border-top: 1px solid var(--line); }
.evidence-type { margin-bottom: 8px; color: #626974 !important; font-size: 12px; font-weight: 600; }
.evidence-card h3 { margin-bottom: 16px; font-family: var(--serif); font-size: 23px; font-weight: 500; }
.finding-block, .limit-block { display: grid; grid-template-columns: 85px 1fr; gap: 15px; margin: 11px 0; }
.finding-block > span, .limit-block > span { color: #626974; font-size: 12px; font-weight: 700; letter-spacing: .06em; text-transform: uppercase; }
.finding-block p, .limit-block p { margin: 0; font-size: 15px; }
.limit-block { padding: 11px 13px; background: #f5f6f8; }
.citation-row { display: flex; flex-wrap: wrap; gap: 12px 20px; margin-top: 14px; }
.citation-row a, .source-link { color: var(--blue-dark); font-size: 13px; font-weight: 600; text-decoration: none; }
.citation-row a:hover, .source-link:hover { text-decoration: underline; text-underline-offset: 3px; }
.read-study { margin-top: 23px; padding: 17px 20px; background: var(--wash-blue); }
.read-study ul { display: grid; grid-template-columns: 1fr 1fr; gap: 7px 26px; margin: 0; padding-left: 19px; color: #424a55; font-size: 13px; }
.dose-card { padding: 21px 23px; border: 1px solid #d5dfed; background: #f7faff; }
.dose-card h3 { margin-bottom: 12px; font-family: var(--serif); font-size: 23px; font-weight: 500; }
.dose-card p { font-size: 15px; }
.dose-amount { padding-top: 12px; border-top: 1px solid #d9e3f0; font-weight: 600; }
.timeline { display: grid; gap: 0; margin: 0; padding: 0; list-style: none; }
.timeline li { display: grid; grid-template-columns: 76px 1fr; gap: 18px; padding: 14px 0; border-top: 1px solid var(--line); }
.timeline li:last-child { border-bottom: 1px solid var(--line); }
.timeline-year { color: var(--blue-dark); font-size: 13px; font-weight: 700; }
.timeline p { margin: 0; color: #484e57; font-size: 15px; }
.chemistry-list { border-top: 1px solid var(--line); }
.chemistry-list > div { display: grid; grid-template-columns: 140px 1fr; gap: 18px; padding: 14px 0; border-bottom: 1px solid var(--line); }
.chemistry-list span { color: #59606a; font-size: 13px; font-weight: 700; }
.chemistry-list p { margin: 0; font-size: 15px; }
.source-link { display: inline-flex; gap: 5px; margin-top: 5px; }
.editorial-status { margin: 22px 0 0; padding: 12px 14px; color: #555d68 !important; background: #f4f5f7; font-size: 13px; }
.next-reading { display: flex; justify-content: space-between; gap: 30px; padding-top: 35px; padding-bottom: 48px; border-top: 1px solid var(--line); }
.next-reading h2 { margin-bottom: 0; font-size: 28px; }
.next-links { display: grid; grid-template-columns: repeat(3, auto); gap: 12px 18px; align-content: center; }
.next-links a { color: var(--blue-dark); font-size: 14px; text-decoration: none; }
.next-links a:hover { text-decoration: underline; }

.universe-grid { display: grid; grid-template-columns: repeat(3, minmax(0, 1fr)); gap: 25px; padding-bottom: 62px; }
.universe-card { padding: 20px 16px 21px 0; border-top: 2px solid #313943; }
.universe-index { display: block; margin-bottom: 26px; color: var(--blue); font-family: var(--serif); font-size: 23px; }
.universe-card .eyebrow { min-height: 30px; margin-bottom: 9px; }
.universe-number { margin: 0; color: #1b2735; font-family: var(--serif); font-size: clamp(28px, 3.1vw, 43px); letter-spacing: -.04em; line-height: 1.15; }
.universe-unit { margin: 4px 0 13px; color: var(--blue-dark) !important; font-size: 14px; font-weight: 600; }
.universe-card > p:not(.eyebrow):not(.universe-number):not(.universe-unit) { font-size: 14px; }
.count-note { display: grid; grid-template-columns: .85fr 1.15fr; gap: 46px; padding-top: 41px; padding-bottom: 43px; border-top: 1px solid var(--line); }
.count-note h2 { font-size: 35px; }
.count-note > div:nth-child(2) p { font-size: 16px; }
.correction-panel { margin-bottom: 85px; padding: 29px; border-left: 3px solid #557caf; background: #f1f6ff; }
.correction-panel h2 { margin-bottom: 9px; font-size: 31px; }
.correction-panel p:last-child { margin-bottom: 0; color: #48515d; }

.principles-grid { padding-bottom: 55px; }
.principle-row { display: grid; grid-template-columns: 63px 1fr; gap: 20px; padding: 20px 0; border-top: 1px solid var(--line); }
.principle-row > span { color: var(--blue); font-family: var(--serif); font-size: 25px; }
.principle-row h2 { margin: 0 0 5px; font-family: var(--sans); font-size: 18px; font-weight: 600; letter-spacing: 0; }
.principle-row p { margin-bottom: 0; color: #555c66; font-size: 15px; }
.source-library { padding-bottom: 85px; }
.source-library .section-heading-line { padding-bottom: 10px; border-bottom: 1px solid var(--line); }
.source-library .section-heading-line > p { margin-bottom: 0; color: #646b75; font-size: 13px; }
.source-list { border-top: 1px solid var(--line); }
.source-item { display: grid; grid-template-columns: minmax(0, 1fr) 195px; gap: 24px; padding: 18px 0; border-bottom: 1px solid var(--line); }
.source-type { margin-bottom: 6px; color: #67707b !important; font-size: 11px !important; font-weight: 700; letter-spacing: .06em; text-transform: uppercase; }
.source-item h3 { margin: 0 0 7px; font-size: 17px; }
.source-item h3 a { color: #242a32; text-decoration: none; }
.source-item h3 a:hover { color: var(--blue-dark); text-decoration: underline; }
.source-item > div > p:last-child { margin-bottom: 0; color: #5a616b; font-size: 13px; }
.source-date { color: #4e5660 !important; font-size: 12px; text-align: right; }
.source-date span { color: #737984; }

.site-footer { display: grid; grid-template-columns: 1fr auto; gap: 15px 40px; align-items: center; padding: 28px clamp(22px, 5vw, 76px) 25px; border-top: 1px solid var(--line); background: #f8f9fa; }
.brand-small { font-size: 19px; }
.site-footer > div:first-child p { margin: 5px 0 0; color: #626a74; font-size: 13px; }
.footer-links { display: flex; flex-wrap: wrap; gap: 14px 22px; }
.footer-links a { color: #45515e; font-size: 13px; text-decoration: none; }
.footer-links a:hover { text-decoration: underline; }
.footer-note { grid-column: 1 / -1; max-width: none; margin: 4px 0 0; padding-top: 12px; border-top: 1px solid #e4e6e9; color: #6a7079; font-size: 12px; }

@media (max-width: 920px) {
  .site-header { flex-wrap: wrap; gap: 14px 24px; }
  .primary-nav { order: 3; flex-basis: 100%; }
  .header-search { margin-left: auto; }
  .home-hero { grid-template-columns: 1fr; padding-inline: clamp(20px, 6vw, 60px); }
  .hero-aside { display: none; }
  .home-note { grid-template-columns: 1fr 1fr; }
  .home-note .text-link { grid-column: 2; }
  .dossier-layout { grid-template-columns: 150px minmax(0, 1fr); gap: 32px; }
  .universe-grid { grid-template-columns: 1fr 1fr; }
  .universe-card:last-child { grid-column: 1 / -1; }
  .next-reading { display: grid; }
}

@media (max-width: 640px) {
  body { line-height: 1.58; }
  .site-header { padding: 14px 18px; gap: 14px; }
  .brand { font-size: 22px; }
  .header-search { order: 3; width: 100%; min-width: 0; margin: 0; }
  .primary-nav { order: 2; flex: 1; justify-content: flex-end; gap: 13px; }
  .primary-nav a { font-size: 12px; }
  .header-search input { font-size: 13px; }
  .header-search .search-submit { padding-inline: 12px; }
  .section-wrap { width: min(100% - 36px, 540px); }
  .home-hero { min-height: auto; margin: 12px 10px 0; padding: 46px 14px 39px; }
  .hero-copy h1 { font-size: clamp(39px, 11vw, 53px); }
  .hero-deck { font-size: 16px; }
  .hero-search { gap: 7px; padding: 6px 6px 6px 12px; }
  .hero-search input { font-size: 13px; }
  .hero-search button { min-height: 40px; padding: 8px 12px; font-size: 12px; white-space: nowrap; }
  .search-scope { font-size: 12px; }
  .home-featured { padding-top: 48px; padding-bottom: 47px; }
  .section-heading-line { display: block; }
  .section-heading-line > .text-link { margin-top: 14px; }
  .catalog-grid { grid-template-columns: 1fr; }
  .catalog-card { padding-top: 20px; }
  .home-note { grid-template-columns: 1fr; gap: 14px; padding-top: 28px; padding-bottom: 31px; }
  .home-note .text-link { grid-column: auto; }
  .landscape-teaser { padding: 35px 0; }
  .teaser-inner { display: grid; gap: 22px; }
  .button-outline { justify-self: start; }
  .page-intro { padding-top: 48px; padding-bottom: 30px; }
  .page-intro h1 { font-size: clamp(39px, 10vw, 56px); }
  .page-intro > p:not(.eyebrow) { font-size: 16px; }
  .filter-bar { margin-bottom: 22px; }
  .filter-bar button { min-height: 44px; }
  .dossier-headband { margin: 10px 8px 0; }
  .dossier-heading { padding-top: 18px; padding-bottom: 29px; }
  .breadcrumb { margin-bottom: 23px; }
  .dossier-heading h1 { font-size: clamp(48px, 13vw, 66px); }
  .dossier-subtitle { font-size: 19px; }
  .dossier-layout { display: block; width: calc(100% - 36px); padding-top: 23px; padding-bottom: 54px; }
  .section-index { position: static; margin-bottom: 24px; padding: 12px 0 15px; border-bottom: 1px solid var(--line); }
  .section-index .eyebrow { margin-bottom: 8px; }
  .section-index nav { grid-template-columns: repeat(2, minmax(0, 1fr)); gap: 2px 8px; }
  .section-index nav a { padding: 7px 8px; font-size: 12px; }
  .dossier-section { padding: 32px 0 35px; }
  .dossier-section:first-child { padding-top: 0; }
  .section-title h2 { font-size: 32px; }
  .lede { font-size: 18px; }
  .boundary-row { grid-template-columns: 1fr; gap: 6px; }
  .fact-strip { gap: 15px; }
  .safety-callout { grid-template-columns: 27px 1fr; gap: 10px; padding: 14px; }
  .safety-callout p { font-size: 14px; }
  .finding-block, .limit-block { grid-template-columns: 1fr; gap: 4px; }
  .read-study ul { grid-template-columns: 1fr; }
  .dose-card { padding: 17px; }
  .chemistry-list > div { grid-template-columns: 1fr; gap: 3px; }
  .timeline li { grid-template-columns: 58px 1fr; gap: 12px; }
  .source-item { grid-template-columns: 1fr; gap: 5px; }
  .source-date { margin-bottom: 0; text-align: left; }
  .universe-grid { grid-template-columns: 1fr; gap: 30px; }
  .universe-card:last-child { grid-column: auto; }
  .universe-card { padding-right: 0; }
  .count-note { grid-template-columns: 1fr; gap: 12px; }
  .count-note h2 { font-size: 31px; }
  .correction-panel { padding: 22px 18px; }
  .correction-panel h2 { font-size: 27px; }
  .principle-row { grid-template-columns: 43px 1fr; gap: 14px; }
  .source-library .section-heading-line > p { margin-top: 10px; }
  .next-links { grid-template-columns: 1fr; }
  .site-footer { grid-template-columns: 1fr; padding: 23px 18px; }
  .footer-links { justify-content: flex-start; }
}

@media (prefers-reduced-motion: reduce) {
  *, *::before, *::after { scroll-behavior: auto !important; animation-duration: .01ms !important; animation-iteration-count: 1 !important; transition-duration: .01ms !important; }
}

@media (forced-colors: active) {
  .tag, .button-outline, .filter-bar button { border: 1px solid ButtonText; }
  .safety-callout, .dose-card, .limit-block, .correction-panel { border: 1px solid CanvasText; }
}