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Public dataset

Recorded source agreement and disagreement

Show whether sources print one normalized reading, have incompatible units, lack structured comparison context, or contain a context-matched numeric difference.

What this does not mean: agree can mean only that sources print the same normalized reading; it is not clinical-context equivalence, independent replication, or proof. differ requires matching structured context and disjoint comparable values. not_comparable and insufficient_context are not disagreement.
Public rows
1,681
Generated
Schema version
source-consensus/2

Coverage

What this run contains

Compared medicine fields
1,681
Agree
1,282
Differ
0
Not comparable
12
Insufficient context
387
Fields represented
5
bioavailability, halfLife, proteinBinding, tMax, volumeOfDistribution

Method

How the rows were made

  1. Deterministic rules normalize recorded pharmacokinetic readings and compare only like-for-like values.
  2. One normalized printed reading may be agree even when clinical context was not extracted; this reports printed-reading agreement only.
  3. Distinct readings may differ only when their units and denominators are comparable and one matching, non-placeholder population/formulation context was structurally extracted. Otherwise they are insufficient_context.
  4. not_comparable preserves incompatible units or denominators instead of guessing. insufficient_context preserves missing or non-matching structured context instead of manufacturing agreement or disagreement.
  5. The agreement rate describes the distribution of recorded source readings; it is not a probability that a value is true.
  6. Every distinct printed reading retains its unit, population context, source count, and complete source records. The API paginates field rows, never child readings or sources.
  7. documentsExamined is every matching single-substance archive document inspected for that medicine. The generator has no document, reading, or source ceiling, so there is no hidden available-versus-retained remainder.

Limits

Read these before using a row

  • Current label parsing does not structurally extract population or formulation context. Distinct otherwise-comparable readings are therefore insufficient_context, never differ; agree may mean printed-reading agreement only. Source records are complete but are not independent-experiment counts.
  • The current deterministic parser does not structurally extract population or formulation context from these sentences. It records that context as unknown and cannot publish distinct same-unit readings as differ.
  • Neither reading is marked wrong. Population, formulation, route, and other unextracted context may explain the printed difference.
  • Only the recorded fields and source documents in this snapshot are compared.
  • A source count is the number of retained source records in the row, not a count of independent experiments.

Provenance

Source examples

abacavir · bioavailability · agree

15 documents examined; 83% (Unknown: population and formulation context were not structurally extracted from this source sentence.)

FDA_LABEL:5676d391-f9a4-44be-9604-954b3d8d0e2b (opens source in a new tab)
The geometric mean absolute bioavailability of the tablet was 83%.

alemtuzumab · volumeOfDistribution · not_comparable

2 documents examined; 0.18 L/kg (Unknown: population and formulation context were not structurally extracted from this source sentence.); 14.1 L (Unknown: population and formulation context were not structurally extracted from this source sentence.)

FDA_LABEL:4f5f7255-7abc-4328-bd1a-ceaf139ef3e0 (opens source in a new tab)
Distribution After the last 30 mg dose, the mean volume of distribution at steady-state was 0.18 L/kg (range 0.1 to 0.4 L/kg).

abiraterone · halfLife · insufficient_context

31 documents examined; 12 ± 5 hours (Unknown: population and formulation context were not structurally extracted from this source sentence.); 18 hours (Unknown: population and formulation context were not structurally extracted from this source sentence.)

FDA_LABEL:c9eb9b46-f847-40a8-802c-a51b40406d5a (opens source in a new tab)
Elimination In patients with metastatic CRPC, the mean terminal half-life of abiraterone in plasma (mean ± SD) is 12 ± 5 hours.

Artifact used for this view: data/source-consensus.ndjson. The reader resolves the current run first and uses the checked-in compatibility run only when a current artifact is absent.

Schema

Fields in the public projection

FieldTypeMeaning
medicineSlugstringStable RNAWiki medicine route key.
fieldstringRecorded pharmacokinetic field being compared.
comparisonStatestringagree (printed-reading agreement), differ (context-matched comparable disjoint values), not_comparable (unit/denominator mismatch), or insufficient_context. Every state remains declared even when its current count is zero.
comparisonReasonsstring[]Deterministic codes explaining the state.
documentsExaminednumberRecorded source documents considered for the field.
sourceCountnumberRecorded source readings represented.
agreementRatenumberShare represented by the leading normalized printed-reading group; not a confidence score or clinical agreement probability.
readingsconsensus-reading[]Complete, untruncated reading groups. Each keeps the printed display, numeric value when parsed, unit, population context, source count, and every source identity, version/effective date or explicit absence, retrieval date, locator, safe link, and excerpt.

Reader

Search and filter the rows

Case-insensitive text search over the public fields named for this dataset.

Exact comparability state.

Exact recorded field key.

Clear

Showing 971980 of 1,681 matching rows. Filters and search terms remain attached when you move between pages or open the API view.

  1. Projected row 971

    Medicine slug
    methylergonovine
    Compared field
    bioavailability
    Comparison state
    agree
    Reason codes
    • COMPATIBLE_VALUES_OVERLAP
    Documents examined
    15
    Source count
    15
    Agreement rate
    1
    Recorded readings
    1. 60%

      Numeric value
      60
      Unit
      %
      Source records
      15

      Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.

      Show all 15 source records
      1. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:3f04ca06-fe52-46d6-96cd-2e77ef6fa36f (opens source in a new tab)

        Methylergonovine label

        Version not recorded · Effective date not recorded

        The bioavailability after oral administration was reported to be about 60% with no accumulation after repeated doses.
      2. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:a7ec8dfe-9b58-4363-a709-c1b72ee67855 (opens source in a new tab)

        Methylergonovine label

        Version not recorded · Effective date not recorded

        The bioavailability after oral administration was reported to be about 60% with no accumulation after repeated doses.
      3. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:4ddcdfff-1468-bff0-e063-6294a90a5480 (opens source in a new tab)

        Methylergonovine label

        Version not recorded · Effective date not recorded

        The bioavailability after oral administration was reported to be about 60% with no accumulation after repeated doses.
      4. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:b49b1e4c-de20-446d-b80a-75c7f0d41ddf (opens source in a new tab)

        Methylergonovine label

        Version not recorded · Effective date not recorded

        The bioavailability after oral administration was reported to be about 60% with no accumulation after repeated doses.
      5. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:8bccff44-2a39-400a-b8a4-2eb5249fdbc8 (opens source in a new tab)

        Methylergonovine label

        Version not recorded · Effective date not recorded

        The bioavailability after oral administration was reported to be about 60% with no accumulation after repeated doses.
      6. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:465b292b-0e0e-4a55-894e-90234efe2a12 (opens source in a new tab)

        Methylergonovine label

        Version not recorded · Effective date not recorded

        The bioavailability after oral administration was reported to be about 60% with no accumulation after repeated doses.
      7. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:885b98d9-ba2c-48fb-b3b8-940e5f5e93d6 (opens source in a new tab)

        Methylergonovine label

        Version not recorded · Effective date not recorded

        The bioavailability after oral administration was reported to be about 60%, with no accumulation after repeated doses.
      8. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:98ad5af1-bde6-4137-a599-b6354d664da4 (opens source in a new tab)

        Methylergonovine label

        Version not recorded · Effective date not recorded

        The bioavailability after oral administration was reported to be about 60% with no accumulation after repeated doses.
      9. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:17ee0c79-ac98-4400-ae77-985978fca07e (opens source in a new tab)

        Methylergonovine label

        Version not recorded · Effective date not recorded

        The bioavailability after oral administration was reported to be about 60% with no accumulation after repeated doses.
      10. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:a9a3079e-b62b-4858-920e-d8f5cb38481e (opens source in a new tab)

        Methylergonovine label

        Version not recorded · Effective date not recorded

        The bioavailability after oral administration was reported to be about 60% with no accumulation after repeated doses.
      11. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:8a6fe76c-d709-419e-885e-fa2ce07df27b (opens source in a new tab)

        Methylergonovine label

        Version not recorded · Effective date not recorded

        The bioavailability after oral administration was reported to be about 60%, with no accumulation after repeated doses.
      12. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:d8e4b8ed-3289-4611-8a61-2392a4bf6072 (opens source in a new tab)

        Methylergonovine label

        Version not recorded · Effective date not recorded

        The bioavailability after oral administration was reported to be about 60% with no accumulation after repeated doses.
      13. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:0a318b77-d280-4571-992f-82e2e0a57c9b (opens source in a new tab)

        Methylergonovine label

        Version not recorded · Effective date not recorded

        The bioavailability after oral administration was reported to be about 60% with no accumulation after repeated doses.
      14. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:c7f19e89-8b52-4033-9914-f3b41fe0790d (opens source in a new tab)

        Methylergonovine label

        Version not recorded · Effective date not recorded

        The bioavailability after oral administration was reported to be about 60% with no accumulation after repeated doses.
      15. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:c4c48277-eb9e-6150-e053-2a95a90ab21d (opens source in a new tab)

        Methylergonovine label

        Version not recorded · Effective date not recorded

        The bioavailability after oral administration was reported to be about 60%, with no accumulation after repeated doses.
  2. Projected row 972

    Medicine slug
    methylergonovine
    Compared field
    halfLife
    Comparison state
    agree
    Reason codes
    • COMPATIBLE_VALUES_OVERLAP
    Documents examined
    15
    Source count
    15
    Agreement rate
    1
    Recorded readings
    1. 3.39 hours

      Numeric value
      3.39
      Unit
      hours
      Source records
      15

      Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.

      Show all 15 source records
      1. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:3f04ca06-fe52-46d6-96cd-2e77ef6fa36f (opens source in a new tab)

        Methylergonovine label

        Version not recorded · Effective date not recorded

        The plasma level decline was biphasic with a mean elimination half-life of 3.39 hours (range 1.5 to 12.7 hours).
      2. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:a7ec8dfe-9b58-4363-a709-c1b72ee67855 (opens source in a new tab)

        Methylergonovine label

        Version not recorded · Effective date not recorded

        The decline of plasma level of intramuscularly administered methylergonovine was biphasic with a mean elimination half-life of 3.39 hours (range 1.5 to 12.7 hours).
      3. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:4ddcdfff-1468-bff0-e063-6294a90a5480 (opens source in a new tab)

        Methylergonovine label

        Version not recorded · Effective date not recorded

        The decline of plasma level of intramuscularly administered methylergonovine was biphasic with a mean elimination half-life of 3.39 hours (range 1.5 to 12.7 hours).
      4. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:b49b1e4c-de20-446d-b80a-75c7f0d41ddf (opens source in a new tab)

        Methylergonovine label

        Version not recorded · Effective date not recorded

        The decline of plasma level of intramuscularly administered methylergonovine was biphasic with a mean elimination half-life of 3.39 hours (range 1.5 to 12.7 hours).
      5. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:8bccff44-2a39-400a-b8a4-2eb5249fdbc8 (opens source in a new tab)

        Methylergonovine label

        Version not recorded · Effective date not recorded

        The decline of plasma level of intramuscularly administered methylergonovine was biphasic with a mean elimination half-life of 3.39 hours (range 1.5 to 12.7 hours).
      6. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:465b292b-0e0e-4a55-894e-90234efe2a12 (opens source in a new tab)

        Methylergonovine label

        Version not recorded · Effective date not recorded

        The decline of plasma level of intramuscularly administered methylergonovine was biphasic with a mean elimination half-life of 3.39 hours (range 1.5 to 12.7 hours).
      7. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:885b98d9-ba2c-48fb-b3b8-940e5f5e93d6 (opens source in a new tab)

        Methylergonovine label

        Version not recorded · Effective date not recorded

        The plasma level decline was biphasic, with a mean elimination half-life of 3.39 hours (range 1.5 to 12.7 hours).
      8. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:98ad5af1-bde6-4137-a599-b6354d664da4 (opens source in a new tab)

        Methylergonovine label

        Version not recorded · Effective date not recorded

        The plasma level decline was biphasic with a mean elimination half-life of 3.39 hours (range 1.5 to 12.7 hours).
      9. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:17ee0c79-ac98-4400-ae77-985978fca07e (opens source in a new tab)

        Methylergonovine label

        Version not recorded · Effective date not recorded

        The decline of plasma level of intramuscularly administered methylergonovine was biphasic with a mean elimination half-life of 3.39 hours (range 1.5 to 12.7 hours).
      10. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:a9a3079e-b62b-4858-920e-d8f5cb38481e (opens source in a new tab)

        Methylergonovine label

        Version not recorded · Effective date not recorded

        The decline of plasma level of intramuscularly administered methylergonovine was biphasic with a mean elimination half-life of 3.39 hours (range 1.5 to 12.7 hours).
      11. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:8a6fe76c-d709-419e-885e-fa2ce07df27b (opens source in a new tab)

        Methylergonovine label

        Version not recorded · Effective date not recorded

        The plasma level decline was biphasic, with a mean elimination half-life of 3.39 hours (range 1.5 to 12.7 hours).
      12. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:d8e4b8ed-3289-4611-8a61-2392a4bf6072 (opens source in a new tab)

        Methylergonovine label

        Version not recorded · Effective date not recorded

        The decline of plasma level of intramuscularly administered methylergonovine was biphasic with a mean elimination half-life of 3.39 hours (range 1.5 to 12.7 hours).
      13. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:0a318b77-d280-4571-992f-82e2e0a57c9b (opens source in a new tab)

        Methylergonovine label

        Version not recorded · Effective date not recorded

        The plasma level decline was biphasic with a mean elimination half-life of 3.39 hours (range 1.5 to 12.7 hours).
      14. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:c7f19e89-8b52-4033-9914-f3b41fe0790d (opens source in a new tab)

        Methylergonovine label

        Version not recorded · Effective date not recorded

        The decline of plasma level of intramuscularly administered methylergonovine was biphasic with a mean elimination half-life of 3.39 hours (range 1.5 to 12.7 hours).
      15. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:c4c48277-eb9e-6150-e053-2a95a90ab21d (opens source in a new tab)

        Methylergonovine label

        Version not recorded · Effective date not recorded

        The plasma level decline was biphasic, with a mean elimination half-life of 3.39 hours (range 1.5 to 12.7 hours).
  3. Projected row 973

    Medicine slug
    methylergonovine
    Compared field
    tMax
    Comparison state
    agree
    Reason codes
    • COMPATIBLE_VALUES_OVERLAP
    Documents examined
    15
    Source count
    15
    Agreement rate
    1
    Recorded readings
    1. 1.12 ± 0.82 hours

      Numeric value
      1.12
      Unit
      hours
      Source records
      15

      Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.

      Show all 15 source records
      1. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:3f04ca06-fe52-46d6-96cd-2e77ef6fa36f (opens source in a new tab)

        Methylergonovine label

        Version not recorded · Effective date not recorded

        Bioavailability studies conducted in fasting healthy female volunteers have shown that oral absorption of a 0.2 mg methylergonovine tablet was fairly rapid with a mean peak plasma concentration of 3243 ± 1308 pg/mL observed at 1.12 ± 0.82 hours.
      2. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:a7ec8dfe-9b58-4363-a709-c1b72ee67855 (opens source in a new tab)

        Methylergonovine label

        Version not recorded · Effective date not recorded

        Bioavailability studies conducted in fasting healthy female volunteers have shown that oral absorption of a 0.2 mg methylergonovine tablet was fairly rapid with a mean peak plasma concentration of 3,243 ± 1,308 pg/mL observed at 1.12 ± 0.82 hours.
      3. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:4ddcdfff-1468-bff0-e063-6294a90a5480 (opens source in a new tab)

        Methylergonovine label

        Version not recorded · Effective date not recorded

        Bioavailability studies conducted in fasting healthy female volunteers have shown that oral absorption of a 0.2 mg methylergonovine tablet was fairly rapid with a mean peak plasma concentration of 3243 ± 1308 pg/mL observed at 1.12 ± 0.82 hours.
      4. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:b49b1e4c-de20-446d-b80a-75c7f0d41ddf (opens source in a new tab)

        Methylergonovine label

        Version not recorded · Effective date not recorded

        Bioavailability studies conducted in fasting healthy female volunteers have shown that oral absorption of a 0.2 mg methylergonovine tablet was fairly rapid with a mean peak plasma concentration of 3243 ± 1308 pg/mL observed at 1.12 ± 0.82 hours.
      5. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:8bccff44-2a39-400a-b8a4-2eb5249fdbc8 (opens source in a new tab)

        Methylergonovine label

        Version not recorded · Effective date not recorded

        Bioavailability studies conducted in fasting healthy female volunteers have shown that oral absorption of a 0.2 mg methylergonovine tablet was fairly rapid with a mean peak plasma concentration of 3243 ± 1308 pg/mL observed at 1.12 ± 0.82 hours.
      6. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:465b292b-0e0e-4a55-894e-90234efe2a12 (opens source in a new tab)

        Methylergonovine label

        Version not recorded · Effective date not recorded

        Bioavailability studies conducted in fasting healthy female volunteers have shown that oral absorption of a 0.2 mg methylergonovine tablet was fairly rapid with a mean peak plasma concentration of 3243 ± 1308 pg/mL observed at 1.12 ± 0.82 hours.
      7. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:885b98d9-ba2c-48fb-b3b8-940e5f5e93d6 (opens source in a new tab)

        Methylergonovine label

        Version not recorded · Effective date not recorded

        Bioavailability studies conducted in fasting healthy female volunteers have shown that oral absorption of a 0.2 mg methylergonovine tablet was fairly rapid, with a mean peak plasma concentration of 3243 ± 1308 pg/mL observed at 1.12 ± 0.82 hours.
      8. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:98ad5af1-bde6-4137-a599-b6354d664da4 (opens source in a new tab)

        Methylergonovine label

        Version not recorded · Effective date not recorded

        Bioavailability studies conducted in fasting healthy female volunteers have shown that oral absorption of a 0.2 mg methylergonovine tablet was fairly rapid with a mean peak plasma concentration of 3243 ± 1308 pg/mL observed at 1.12 ± 0.82 hours.
      9. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:17ee0c79-ac98-4400-ae77-985978fca07e (opens source in a new tab)

        Methylergonovine label

        Version not recorded · Effective date not recorded

        Bioavailability studies conducted in fasting healthy female volunteers have shown that oral absorption of a 0.2 mg methylergonovine tablet was fairly rapid with a mean peak plasma concentration of 3243 ± 1308 pg/mL observed at 1.12 ± 0.82 hours.
      10. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:a9a3079e-b62b-4858-920e-d8f5cb38481e (opens source in a new tab)

        Methylergonovine label

        Version not recorded · Effective date not recorded

        Bioavailability studies conducted in fasting healthy female volunteers have shown that oral absorption of a 0.2 mg methylergonovine tablet was fairly rapid with a mean peak plasma concentration of 3243 ± 1308 pg/mL observed at 1.12 ± 0.82 hours.
      11. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:8a6fe76c-d709-419e-885e-fa2ce07df27b (opens source in a new tab)

        Methylergonovine label

        Version not recorded · Effective date not recorded

        Bioavailability studies conducted in fasting healthy female volunteers have shown that oral absorption of a 0.2 mg methylergonovine tablet was fairly rapid, with a mean peak plasma concentration of 3243 ± 1308 pg/mL observed at 1.12 ± 0.82 hours.
      12. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:d8e4b8ed-3289-4611-8a61-2392a4bf6072 (opens source in a new tab)

        Methylergonovine label

        Version not recorded · Effective date not recorded

        Bioavailability studies conducted in fasting healthy female volunteers have shown that oral absorption of a 0.2 mg methylergonovine tablet was fairly rapid with a mean peak plasma concentration of 3243 ± 1308 pg/mL observed at 1.12 ± 0.82 hours.
      13. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:0a318b77-d280-4571-992f-82e2e0a57c9b (opens source in a new tab)

        Methylergonovine label

        Version not recorded · Effective date not recorded

        Bioavailability studies conducted in fasting healthy female volunteers have shown that oral absorption of a 0.2 mg methylergonovine tablet was fairly rapid with a mean peak plasma concentration of 3243 ± 1308 pg/mL observed at 1.12 ± 0.82 hours.
      14. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:c7f19e89-8b52-4033-9914-f3b41fe0790d (opens source in a new tab)

        Methylergonovine label

        Version not recorded · Effective date not recorded

        Bioavailability studies conducted in fasting healthy female volunteers have shown that oral absorption of a 0.2 mg methylergonovine tablet was fairly rapid with a mean peak plasma concentration of 3243 ± 1308 pg/mL observed at 1.12 ± 0.82 hours.
      15. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:c4c48277-eb9e-6150-e053-2a95a90ab21d (opens source in a new tab)

        Methylergonovine label

        Version not recorded · Effective date not recorded

        Bioavailability studies conducted in fasting healthy female volunteers have shown that oral absorption of a 0.2 mg methylergonovine tablet was fairly rapid, with a mean peak plasma concentration of 3243 ± 1308 pg/mL observed at 1.12 ± 0.82 hours.
  4. Projected row 974

    Medicine slug
    methylergonovine
    Compared field
    volumeOfDistribution
    Comparison state
    agree
    Reason codes
    • COMPATIBLE_VALUES_OVERLAP
    Documents examined
    15
    Source count
    6
    Agreement rate
    1
    Recorded readings
    1. 56.1 ± 17.0 liters

      Numeric value
      56.1
      Unit
      L
      Source records
      6

      Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.

      Show all 6 source records
      1. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:3f04ca06-fe52-46d6-96cd-2e77ef6fa36f (opens source in a new tab)

        Methylergonovine label

        Version not recorded · Effective date not recorded

        The volume of distribution (Vd ss /F) of methylergonovine was calculated to be 56.1 ± 17.0 liters, and the plasma clearance (CLp/F) was calculated to be 14.4 ± 4.5 liters per hour.
      2. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:885b98d9-ba2c-48fb-b3b8-940e5f5e93d6 (opens source in a new tab)

        Methylergonovine label

        Version not recorded · Effective date not recorded

        The volume of distribution (Vd SS /F) of methylergonovine was calculated to be 56.1 ± 17.0 liters, and the plasma clearance (CLp/F) was calculated to be 14.4 ± 4.5 liters per hour.
      3. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:98ad5af1-bde6-4137-a599-b6354d664da4 (opens source in a new tab)

        Methylergonovine label

        Version not recorded · Effective date not recorded

        The volume of distribution (V dss /F) of methylergonovine was calculated to be 56.1 ± 17.0 liters, and the plasma clearance (CLp/F) was calculated to be 14.4 ± 4.5 liters per hour.
      4. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:8a6fe76c-d709-419e-885e-fa2ce07df27b (opens source in a new tab)

        Methylergonovine label

        Version not recorded · Effective date not recorded

        The volume of distribution (Vd SS /F) of methylergonovine was calculated to be 56.1 ± 17.0 liters, and the plasma clearance (CLp/F) was calculated to be 14.4 ± 4.5 liters per hour.
      5. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:0a318b77-d280-4571-992f-82e2e0a57c9b (opens source in a new tab)

        Methylergonovine label

        Version not recorded · Effective date not recorded

        The volume of distribution (Vd ss /F) of methylergonovine was calculated to be 56.1 ± 17.0 liters, and the plasma clearance (CLp/F) was calculated to be 14.4 ± 4.5 liters per hour.
      6. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:c4c48277-eb9e-6150-e053-2a95a90ab21d (opens source in a new tab)

        Methylergonovine label

        Version not recorded · Effective date not recorded

        The volume of distribution (VdSS/F) of methylergonovine was calculated to be 56.1 ± 17.0 liters, and the plasma clearance (CLp/F) was calculated to be 14.4 ± 4.5 liters per hour.
  5. Projected row 975

    Medicine slug
    methylphenidate
    Compared field
    bioavailability
    Comparison state
    insufficient_context
    Reason codes
    • STRUCTURED_CONTEXT_MISSING
    Documents examined
    86
    Source count
    17
    Agreement rate
    0.647059
    Recorded readings
    1. 22 ± 8 %

      Numeric value
      22
      Unit
      %
      Source records
      11

      Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.

      Show all 11 source records
      1. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:35be77db-fbe3-487e-a220-a08a11aaec28 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics Absorption The absolute bioavailability of methylphenidate is 22 ± 8 % for the d-enantiomer and 5 ± 3 % for the l-enantiomer.
      2. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:e5db854a-1c77-4faf-9e60-daf9c9b6cfa0 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        Absorption The absolute oral bioavailability of methylphenidate in children was 22 ± 8% for d-methylphenidate and 5 ± 3% for l- methylphenidate.
      3. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:c614cf55-b462-4f7e-b19c-6d22a47e509f (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics Absorption The absolute bioavailability of methylphenidate is 22 ± 8% for the d-enantiomer and 5 ± 3% for the l-enantiomer.
      4. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:238ff743-4f25-43a3-87ac-6559d12a9d49 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics Absorption The absolute bioavailability of methylphenidate is 22 ± 8 % for the d-enantiomer and 5 ± 3 % for the l-enantiomer.
      5. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:d6fb2750-cdab-4749-ba0d-7534840a5892 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics Absorption The absolute bioavailability of methylphenidate is 22 ± 8 % for the d-enantiomer and 5 ± 3 % for the l-enantiomer.
      6. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:778190da-1528-4def-94bf-ee23ee5268a5 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        This was below the threshold of clinical concern and there was no evident exposure response relationship. 12.3 Pharmacokinetics Absorption The absolute bioavailability of methylphenidate is 22 ± 8 % for the d-enantiomer and 5 ± 3 % for the l-enantiomer.
      7. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:034fb7cd-e183-475e-8beb-64fd88facc8f (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        Absorption The absolute oral bioavailability of methylphenidate in children was 22 ± 8% for d-methylphenidate and 5 ± 3% for l- methylphenidate.
      8. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:c0bf0835-6a2f-4067-a158-8b86c4b0668a (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics Absorption The absolute bioavailability of methylphenidate is 22 ± 8 % for the d-enantiomer and 5 ± 3 % for the l-enantiomer.
      9. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:1bf37f9f-29cf-4b09-9c81-eb369e35a042 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        This was below the threshold of clinical concern and there was no evident exposure response relationship. 12.3 Pharmacokinetics Absorption The absolute bioavailability of methylphenidate is 22 ± 8 % for the d-enantiomer and 5 ± 3 % for the l-enantiomer.
      10. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:d8c14df4-ac05-d69d-9308-58a51d568329 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        Absorption The absolute oral bioavailability of methylphenidate in children was 22 ± 8% for d-methylphenidate and 5 ± 3% for l- methylphenidate.
      11. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:1a89b390-0cd5-45cb-9e70-20de44652c56 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics Absorption The absolute bioavailability of methylphenidate is 22 ± 8 % for the d-enantiomer and 5 ± 3 % for the l-enantiomer.
    2. 22%

      Numeric value
      22
      Unit
      %
      Source records
      4

      Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.

      Show all 4 source records
      1. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:effd952d-ac94-47bb-b107-589a4934dcca (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        Absorption The absolute oral bioavailability of methylphenidate in children was 22% ± 8% for d-methylphenidate and 5% ± 3% for l-methylphenidate.
      2. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:27ea91ad-f64e-43d7-ab10-6f988bca5379 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        Absorption The absolute oral bioavailability of methylphenidate in children was 22% ± 8% for d-methylphenidate and 5% ± 3% for l-methylphenidate.
      3. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:44386394-d2a3-4483-abe1-6c5c634cc501 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        Absorption The absolute oral bioavailability of methylphenidate in children was 22% ± 8% for d-methylphenidate and 5% ± 3% for l-methylphenidate.
      4. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:1f8983ce-71b8-4c62-830d-e4692ddededa (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        Absorption The absolute oral bioavailability of methylphenidate in children was 22% ± 8% for d-methylphenidate and 5% ± 3% for l-methylphenidate.
    3. 102%

      Numeric value
      102
      Unit
      %
      Source records
      2

      Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.

      Show all 2 source records
      1. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:f7a7ffd1-bc30-4db8-8391-dddf76acd639 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The relative bioavailability is 102%.
      2. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:ecbb4a30-21ac-42e1-b4e9-6c35344ffc45 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The relative bioavailability is 102%.
  6. Projected row 976

    Medicine slug
    methylphenidate
    Compared field
    halfLife
    Comparison state
    insufficient_context
    Reason codes
    • STRUCTURED_CONTEXT_MISSING
    Documents examined
    86
    Source count
    38
    Agreement rate
    0.447368
    Recorded readings
    1. 3.6 hours

      Numeric value
      3.6
      Unit
      hours
      Source records
      17

      Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.

      Show all 17 source records
      1. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:7124df7e-6273-a68d-6e35-dc06122d8686 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The mean half-life was about 3.6 hours.
      2. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:85ef422d-af27-4126-9841-6892af1871d6 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The mean half-life was about 3.6 hours.
      3. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:18024571-4505-6d51-e063-6294a90a1972 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The mean half-life was about 3.6 hours.
      4. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:22d5fa47-b5b9-4fd9-980c-4eb88e95ae5d (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The mean half-life was about 3.6 hours.
      5. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:b07150db-fd99-4400-bb83-b3a7544a917a (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The mean half-life was about 3.6 hours.
      6. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:22e5ddfa-7264-fbb1-e063-6394a90a6483 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The mean half-life was about 3.6 hours.
      7. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:dd8d7b6e-c23d-4e16-bb53-959e9127ebc6 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The mean half-life was about 3.6 hours.
      8. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:b1b0f2ff-d9df-42ab-b471-226ecf97e075 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The mean half-life was about 3.6 hours.
      9. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:b9af3104-172d-4975-9301-b9fe7db9ef12 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The mean half-life was about 3.6 hours.
      10. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:44737c1d-fe75-409e-8a58-591696d3d7aa (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The mean half-life was about 3.6 hours.
      11. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:1a88218c-5b18-4220-8f56-526de1a276cd (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The mean half-life was about 3.6 hours.
      12. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:3d1f5aff-5d39-496c-b5ed-7f3c70ec641c (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The mean half-life was about 3.6 hours.
      13. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:768bf181-d0d8-49e5-9c87-cacbb069e0b2 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The mean half-life was about 3.6 hours.
      14. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:f6581305-cd1e-4171-8c1b-e184c7bde033 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The mean half-life was about 3.6 hours.
      15. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:cd2c1226-fa19-4734-b62d-89fea73dcb0d (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The mean half-life was about 3.6 hours.
      16. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:5a29687b-5294-4b27-a556-514b092a877d (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The mean half-life was about 3.6 hours.
      17. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:c45dc1de-adfa-4b3c-a7dc-cffbc8eac74f (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The mean half-life was about 3.6 hours.
    2. 2.7 hours

      Numeric value
      2.7
      Unit
      hours
      Source records
      11

      Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.

      Show all 11 source records
      1. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:213ca0da-dde8-48ee-ac8c-c66558e6f62d (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        Elimination The mean terminal half-life (t½) of methylphenidate was 2.7 hours following administration of 20 mg methylphenidate hydrochloride oral solution.
      2. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:2cf1b26b-199d-4c7f-ab64-4805a9def2cc (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        Elimination The mean terminal half-life (t½) of methylphenidate was 2.7 hours following administration of 20 mg methylphenidate hydrochloride oral solution.
      3. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:298fb86d-7d94-49e1-b743-3e7801122422 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        Elimination The mean terminal half-life (t½) of methylphenidate was 2.7 hours following administration of 20 mg methylphenidate hydrochloride oral solution.
      4. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:83e70f8f-18dd-45fc-8bc5-4b8f7f23439e (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        Elimination The mean terminal half-life (t1/2) of methylphenidate was 2.7 hours following administration of 20 mg methylphenidate hydrochloride oral solution.
      5. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:ea5a6d4e-60ba-46f3-b314-3c7a970b377d (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        Elimination The mean terminal half-life (t½) of methylphenidate was 2.7 hours following administration of 20 mg methylphenidate hydrochloride oral solution.
      6. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:9e3c22d9-71d9-46a7-b315-8021c94c4bec (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        Elimination The mean terminal half-life (t ½ ) of methylphenidate was 2.7 hours following administration of 20 mg Methylin Oral Solution.
      7. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:57fd619e-687d-403c-a77a-3dc3a1bab65a (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        Elimination The mean terminal half-life (t ½ ) of methylphenidate was 2.7 hours following administration of 20 mg Methylphenidate Hydrochloride Oral Solution.
      8. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:ad3a3865-952e-46cf-8387-1228e2375312 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        Elimination The mean terminal half-life (t1/2) of methylphenidate was 2.7 hours following administration of 20 mg methylphenidate hydrochloride oral solution.
      9. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:5fa3da25-13aa-4ee3-acf5-cd505f4688d0 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        Elimination The mean terminal half-life (t ½ ) of methylphenidate was 2.7 hours following administration of 20 mg methylphenidate hydrochloride oral solution.
      10. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:b9c31526-d486-433c-9b3c-7a12765afe94 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        Elimination The mean terminal half-life (t½) of methylphenidate was 2.7 hours following administration of 20 mg methylphenidate hydrochloride oral solution.
      11. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:e817377f-bc72-415a-acd2-7136746b2479 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        Elimination The mean terminal half-life (t 1/2 ) of methylphenidate was 2.7 hours following administration of 20 mg methylphenidate hydrochloride oral solution.
    3. 3.5 hours

      Numeric value
      3.5
      Unit
      hours
      Source records
      7

      Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.

      Show all 7 source records
      1. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:e5db854a-1c77-4faf-9e60-daf9c9b6cfa0 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        In studies with methylphenidate hydrochloride extended-release capsules (LA) and methylphenidate hydrochloride tablets in adults, methylphenidate from methylphenidate hydrochloride tablets is eliminated from plasma with an average half-life of about 3.5 hours, (range, 1.3 to 7.7 hours).
      2. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:effd952d-ac94-47bb-b107-589a4934dcca (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        In studies with Ritalin LA and Ritalin tablets in adults, methylphenidate from Ritalin tablets is eliminated from plasma with an average half-life of about 3.5 hours, (range, 1.3 to 7.7 hours).
      3. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:27ea91ad-f64e-43d7-ab10-6f988bca5379 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        In studies with methylphenidate hydrochloride extended-release capsules and methylphenidate hydrochloride tablets in adults, methylphenidate from methylphenidate hydrochloride tablets is eliminated from plasma with an average half-life of about 3.5 hours, (range, 1.3 to 7.7 hours).
      4. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:44386394-d2a3-4483-abe1-6c5c634cc501 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        In studies with methylphenidate hydrochloride extended-release capsules and methylphenidate hydrochloride tablets in adults, methylphenidate from methylphenidate hydrochloride tablets is eliminated from plasma with an average half-life of about 3.5 hours, (range, 1.3 to 7.7 hours).
      5. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:034fb7cd-e183-475e-8beb-64fd88facc8f (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        In studies with methylphenidate hydrochloride extended-release capsules and methylphenidate hydrochloride tablets in adults, methylphenidate from methylphenidate hydrochloride tablets is eliminated from plasma with an average half-life of about 3.5 hours, (range 1.3 to 7.7 hours).
      6. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:1f8983ce-71b8-4c62-830d-e4692ddededa (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        In studies with methylphenidate hydrochloride extended-release capsules and methylphenidate hydrochloride tablets in adults, methylphenidate from methylphenidate hydrochloride tablets is eliminated from plasma with an average half-life of about 3.5 hours, (range, 1.3 to 7.7 hours).
      7. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:d8c14df4-ac05-d69d-9308-58a51d568329 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        In studies with methylphenidate hydrochloride extended-release capsules (LA) and methylphenidate hydrochloride tablets in adults, methylphenidate from methylphenidate hydrochloride tablets is eliminated from plasma with an average half-life of about 3.5 hours, (range, 1.3 to 7.7 hours).
    4. 3 hours

      Numeric value
      3
      Unit
      hours
      Source records
      1

      Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.

      Show all 1 source records
      1. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:e5cb0740-813f-4dce-8c29-d7680c66e77c (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        Elimination The mean terminal half-life (t ½ ) of methylphenidate was 3 hours following administration of 20 mg Methylphenidate Hydrochloride Chewable Tablet.
    5. 4 hours

      Numeric value
      4
      Unit
      hours
      Source records
      1

      Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.

      Show all 1 source records
      1. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:33f70f58-c871-42c8-8adb-345caeafefcd (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The mean plasma terminal elimination half-life of methylphenidate was about 4 hours in healthy volunteers following a single 51.8 mg dose administration.
    6. 5.2 hours

      Numeric value
      5.2
      Unit
      hours
      Source records
      1

      Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.

      Show all 1 source records
      1. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:defc1205-8e90-4b1e-b862-05e4c35c7364 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The mean plasma terminal elimination half-life of methylphenidate was about 5.2 hours in healthy volunteers following a single 40 mg dose administration.
  7. Projected row 977

    Medicine slug
    methylphenidate
    Compared field
    proteinBinding
    Comparison state
    agree
    Reason codes
    • COMPATIBLE_VALUES_OVERLAP
    Documents examined
    86
    Source count
    17
    Agreement rate
    1
    Recorded readings
    1. 10%

      Numeric value
      10
      Unit
      %
      Source records
      17

      Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.

      Show all 17 source records
      1. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:213ca0da-dde8-48ee-ac8c-c66558e6f62d (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        Distribution Plasma protein binding is 10% to 33%.
      2. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:be59f8b4-7842-42cc-9559-bfa747f0baa5 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        Distribution Plasma protein binding is 10% to 33%.
      3. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:2cf1b26b-199d-4c7f-ab64-4805a9def2cc (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        Distribution Plasma protein binding is 10% to 33%.
      4. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:e45c75dc-d381-475b-b649-a871c8a36e60 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        Distribution Plasma protein binding is 10% to 33%.
      5. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:10aa0dc0-bd0e-4927-a19a-8722d78ad67d (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        Distribution Plasma protein binding is 10% to 33%.
      6. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:298fb86d-7d94-49e1-b743-3e7801122422 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        Distribution Plasma protein binding is 10% to 33%.
      7. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:e5cb0740-813f-4dce-8c29-d7680c66e77c (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        Distribution Plasma protein binding is 10% to 33%.
      8. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:83e70f8f-18dd-45fc-8bc5-4b8f7f23439e (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        Distribution Plasma protein binding is 10% to 33%.
      9. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:ea5a6d4e-60ba-46f3-b314-3c7a970b377d (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        Distribution Plasma protein binding is 10% to 33%.
      10. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:9e3c22d9-71d9-46a7-b315-8021c94c4bec (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        Distribution Plasma protein binding is 10% to 33%.
      11. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:57fd619e-687d-403c-a77a-3dc3a1bab65a (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        Distribution Plasma protein binding is 10% to 33%.
      12. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:29f06562-6b6a-4ca6-b62e-d08a45fb3dd4 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        Distribution Plasma protein binding is 10% to 33%.
      13. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:ad3a3865-952e-46cf-8387-1228e2375312 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        Distribution Plasma protein binding is 10% to 33%.
      14. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:5fa3da25-13aa-4ee3-acf5-cd505f4688d0 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        Distribution Plasma protein binding is 10% to 33%.
      15. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:b9c31526-d486-433c-9b3c-7a12765afe94 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        Distribution Plasma protein binding is 10% to 33%.
      16. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:9e11e093-4ff3-4bed-8fe9-3ee460b47303 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        Distribution Plasma protein binding is 10% to 33%.
      17. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:e817377f-bc72-415a-acd2-7136746b2479 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        Distribution Plasma protein binding is 10% to 33%.
  8. Projected row 978

    Medicine slug
    methylphenidate
    Compared field
    tMax
    Comparison state
    insufficient_context
    Reason codes
    • STRUCTURED_CONTEXT_MISSING
    Documents examined
    86
    Source count
    30
    Agreement rate
    0.366667
    Recorded readings
    1. 1 to 2 hours

      Numeric value
      1
      Unit
      hours
      Source records
      11

      Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.

      Show all 11 source records
      1. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:213ca0da-dde8-48ee-ac8c-c66558e6f62d (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        tion of 20 mg methylphenidate hydrochloride oral solution and 20 mg tablet of methylphenidate hydrochloride in healthy volunteers under fasted conditions, time to peak plasma concentration (T max ) of methylphenidate was at 1 to 2 hours after dosing, and: • The mean peak plasma concentration (C max ) of methylphenidate was 9.1 ng/mL and 9.8 ng/mL, respectively. • The mean area under concentration
      2. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:2cf1b26b-199d-4c7f-ab64-4805a9def2cc (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        ation of 20 mg methylphenidate hydrochloride oral solution and 20 mg tablet of methylphenidate hydrochloride in healthy volunteers under fasted conditions, time to peak plasma concentration (Tmax) of methylphenidate was at 1 to 2 hours after dosing, and: The mean peak plasma concentration (Cmax) of methylphenidate was 9.1 ng/mL and 9.8 ng/mL, respectively.
      3. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:298fb86d-7d94-49e1-b743-3e7801122422 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        tion of 20 mg methylphenidate hydrochloride oral solution and 20 mg tablet of methylphenidate hydrochloride in healthy volunteers under fasted conditions, time to peak plasma concentration (T max ) of methylphenidate was at 1 to 2 hours after dosing, and: • The mean peak plasma concentration (C max ) of methylphenidate was 9.1 ng/mL and 9.8 ng/mL, respectively. • The mean area under concentration
      4. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:83e70f8f-18dd-45fc-8bc5-4b8f7f23439e (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        tion of 20 mg methylphenidate hydrochloride oral solution and 20 mg tablet of methylphenidate hydrochloride in healthy volunteers under fasted conditions, time to peak plasma concentration (T max ) of methylphenidate was at 1 to 2 hours after dosing, and: The mean peak plasma concentration (C max ) of methylphenidate was 9.1 ng/mL and 9.8 ng/mL, respectively.
      5. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:ea5a6d4e-60ba-46f3-b314-3c7a970b377d (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        tion of 20 mg methylphenidate hydrochloride oral solution and 20 mg tablet of methylphenidate hydrochloride in healthy volunteers under fasted conditions, time to peak plasma concentration (T max ) of methylphenidate was at 1 to 2 hours after dosing, and: • The mean peak plasma concentration (C max ) of methylphenidate was 9.1 ng/mL and 9.8 ng/mL, respectively. • The mean area under concentration
      6. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:9e3c22d9-71d9-46a7-b315-8021c94c4bec (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics Absorption Following a single dose administration of 20 mg Methylin and 20 mg tablet of methylphenidate hydrochloride in healthy volunteers under fasted conditions, time to peak plasma concentration (T max ) of methylphenidate was at 1 to 2 hours after dosing, and: The mean peak plasma concentration (C max ) of methylphenidate was 9.1 ng/mL and 9.8 ng/mL, respectively.
      7. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:57fd619e-687d-403c-a77a-3dc3a1bab65a (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        tion of 20 mg methylphenidate hydrochloride oral solution and 20 mg tablet of methylphenidate hydrochloride in healthy volunteers under fasted conditions, time to peak plasma concentration (T max ) of methylphenidate was at 1 to 2 hours after dosing, and: The mean peak plasma concentration (C max ) of methylphenidate was 9.1 ng/mL and 9.8 ng/mL, respectively.
      8. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:ad3a3865-952e-46cf-8387-1228e2375312 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        tion of 20 mg methylphenidate hydrochloride oral solution and 20 mg tablet of methylphenidate hydrochloride in healthy volunteers under fasted conditions, time to peak plasma concentration (T max ) of methylphenidate was at 1 to 2 hours after dosing, and: The mean peak plasma concentration (C max ) of methylphenidate was 9.1 ng/mL and 9.8 ng/mL, respectively.
      9. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:5fa3da25-13aa-4ee3-acf5-cd505f4688d0 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        tion of 20 mg methylphenidate hydrochloride oral solution and 20 mg tablet of methylphenidate hydrochloride in healthy volunteers under fasted conditions, time to peak plasma concentration (T max ) of methylphenidate was at 1 to 2 hours after dosing, and: The mean peak plasma concentration (C max ) of methylphenidate was 9.1 ng/mL and 9.8 ng/mL, respectively.
      10. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:b9c31526-d486-433c-9b3c-7a12765afe94 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        tion of 20 mg methylphenidate hydrochloride oral solution and 20 mg tablet of methylphenidate hydrochloride in healthy volunteers under fasted conditions, time to peak plasma concentration (T max ) of methylphenidate was at 1 to 2 hours after dosing, and: • The mean peak plasma concentration (C max ) of methylphenidate was 9.1 ng/mL and 9.8 ng/mL, respectively. • The mean area under concentration
      11. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:e817377f-bc72-415a-acd2-7136746b2479 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        tion of 20 mg methylphenidate hydrochloride oral solution and 20 mg tablet of methylphenidate hydrochloride in healthy volunteers under fasted conditions, time to peak plasma concentration (T max ) of methylphenidate was at 1 to 2 hours after dosing, and: The mean peak plasma concentration (C max ) of methylphenidate was 9.1 ng/mL and 9.8 ng/mL, respectively.
    2. 1 to 3 hours

      Numeric value
      1
      Unit
      hours
      Source records
      7

      Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.

      Show all 7 source records
      1. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:e5db854a-1c77-4faf-9e60-daf9c9b6cfa0 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The initial rate of absorption for methylphenidate hydrochloride extended-release capsules (LA) is similar to that of methylphenidate hydrochloride tablets as shown by the similar rate parameters between the 2 formulations, i.e., initial lag time (T lag ), first peak concentration (C max1 ), and time to the first peak (T max1 ), which is reached in 1 to 3 hours.
      2. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:effd952d-ac94-47bb-b107-589a4934dcca (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The initial rate of absorption for Ritalin LA is similar to that of Ritalin tablets as shown by the similar rate parameters between the 2 formulations, i.e., initial lag time (T lag ), first peak concentration (C max1 ), and time to the first peak (T max1 ), which is reached in 1 to 3 hours.
      3. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:27ea91ad-f64e-43d7-ab10-6f988bca5379 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The initial rate of absorption for methylphenidate hydrochloride extended-release capsules is similar to that of methylphenidate hydrochloride tablets as shown by the similar rate parameters between the 2 formulations, i.e., initial lag time (T lag ), first peak concentration (C max1 ), and time to the first peak (T max1 ), which is reached in 1 to 3 hours.
      4. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:44386394-d2a3-4483-abe1-6c5c634cc501 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The initial rate of absorption for methylphenidate hydrochloride extended-release capsules is similar to that of methylphenidate hydrochloride tablets as shown by the similar rate parameters between the 2 formulations, i.e., initial lag time (T lag ), first peak concentration (C max1 ), and time to the first peak (T max1 ), which is reached in 1 to 3 hours.
      5. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:034fb7cd-e183-475e-8beb-64fd88facc8f (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The initial rate of absorption for methylphenidate hydrochloride extended-release capsules are similar to that of methylphenidate hydrochloride tablets as shown by the similar rate parameters between the 2 formulations, i.e., initial lag time (T lag ), first peak concentration (C max1 ), and time to the first peak (T max1 ), which is reached in 1 to 3 hours.
      6. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:1f8983ce-71b8-4c62-830d-e4692ddededa (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The initial rate of absorption for methylphenidate hydrochloride extended-release capsules is similar to that of methylphenidate hydrochloride tablets as shown by the similar rate parameters between the 2 formulations, i.e., initial lag time (T lag ), first peak concentration (C max1 ), and time to the first peak (T max1 ), which is reached in 1 to 3 hours.
      7. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:d8c14df4-ac05-d69d-9308-58a51d568329 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The initial rate of absorption for methylphenidate hydrochloride extended-release capsules (LA) is similar to that of methylphenidate hydrochloride tablets as shown by the similar rate parameters between the 2 formulations, i.e., initial lag time (T lag ), first peak concentration (C max1 ), and time to the first peak (T max1 ), which is reached in 1 to 3 hours.
    3. 1 hour

      Numeric value
      1
      Unit
      hours
      Source records
      6

      Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.

      Show all 6 source records
      1. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:7293dffd-eb01-43d4-b9c4-04f79bec180c (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        Food Effect In a study in adult volunteers investigating the effects of a high-fat meal on the bioavailability of methylphenidate hydrochloride chewable tablets at a dose of 20 mg, the presence of food delayed the peak concentrations by approximately 1 hour (1.5 hours, fasted and 2.4 hours, fed).
      2. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:e5cb0740-813f-4dce-8c29-d7680c66e77c (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        Effect of Food In a study in adult volunteers investigating the effects of a high-fat meal on the bioavailability of Methylphenidate Hydrochloride Chewable Tablets at a dose of 20 mg, the presence of food delayed the peak concentrations by approximately 1 hour (1.5 hours, fasted and 2.4 hours, fed).
      3. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:c2dc2109-44a6-4797-b04e-18761dd9d45a (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        In a study in adult volunteers to investigate the effects of a high-fat meal on the bioavailability of QUILLIVANT XR at a dose of 60 mg, the presence of food reduced the time to peak concentration by approximately 1 hour (fed: 4 hours vs. fasted: 5 hours).
      4. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:91833146-fa95-471a-8b8d-6d36a2db5c9a (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        Food Effect In a study in adult volunteers investigating the effects of a high-fat meal on the bioavailability of methylphenidate hydrochloride chewable tablets at a dose of 20 mg, the presence of food delayed the peak concentrations by approximately 1 hour (1.5 hours, fasted and 2.4 hours, fed).
      5. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:5bfe50ed-171f-4c40-bc0b-20c68e8e2025 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        Food Effect In a study in adult volunteers investigating the effects of a high-fat meal on the bioavailability of methylphenidate hydrochloride chewable tablets at a dose of 20 mg, the presence of food delayed the peak concentrations by approximately 1 hour (1.5 hours, fasted and 2.4 hours, fed).
      6. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:bb73cd3e-aa7c-4f7e-826d-75e71fb6d1e0 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        Food Effect In a study in adult volunteers investigating the effects of a high-fat meal on the bioavailability of methylphenidate hydrochloride chewable tablets at a dose of 20 mg, the presence of food delayed the peak concentrations by approximately 1 hour (1.5 hours, fasted and 2.4 hours, fed).
    4. 4 hours

      Numeric value
      4
      Unit
      hours
      Source records
      3

      Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.

      Show all 3 source records
      1. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:2c312c31-3198-4775-91ab-294e0b4b9e7f (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        When applied to inflamed skin, lag time is no greater than 1 hour, T max is 4 hours, and both C max and AUC are approximately 3-fold higher.
      2. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:1643b6a5-80da-4d4f-8c5f-feb907875702 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        When applied to inflamed skin, lag time is no greater than 1 hour, T max is 4 hours, and both C max and AUC are approximately 3-fold higher.
      3. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:7bcff873-1fc2-45bc-a8e4-5db4edeb9bfb (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        When applied to inflamed skin, lag time is no greater than 1 hour, Tmax is 4 hours, and both Cmax and AUC are approximately 3-fold higher.
    5. 5.5 hours

      Numeric value
      5.5
      Unit
      hours
      Source records
      2

      Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.

      Show all 2 source records
      1. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:22d5fa47-b5b9-4fd9-980c-4eb88e95ae5d (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        Mean time to reach peak plasma concentrations of RELEXXII occurs at 5.5 hours.
      2. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:dd8d7b6e-c23d-4e16-bb53-959e9127ebc6 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        Mean time to reach peak plasma concentrations of methylphenidate hydrochloride extended-release tablets occurs at 5.5 hours.
    6. 2.5 hours

      Numeric value
      2.5
      Unit
      hours
      Source records
      1

      Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.

      Show all 1 source records
      1. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:d95dede0-b1ff-4489-8f91-3bbe122852bf (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        Figure Food Effects Compared to the fasted state, JORNAY PM taken with a high-fat meal at night exhibited similar mean AUC 0-∞ , a 14% lower mean C max , and a median T max extended by approximately 2.5 hours.
  9. Projected row 979

    Medicine slug
    methylphenidate
    Compared field
    volumeOfDistribution
    Comparison state
    agree
    Reason codes
    • COMPATIBLE_VALUES_OVERLAP
    Documents examined
    86
    Source count
    52
    Agreement rate
    1
    Recorded readings
    1. 2.65 ± 1.11 L/kg

      Numeric value
      2.65
      Unit
      L/kg
      Source records
      52

      Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.

      Show all 52 source records
      1. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:98be5c84-b348-6b8e-e053-2995a90ae4cc (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The volume of distribution was 2.65 ± 1.11 L/kg for d-methylphenidate and 1.80 ± 0.91 L/kg for l-methylphenidate.
      2. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:213ca0da-dde8-48ee-ac8c-c66558e6f62d (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The volume of distribution was 2.65 ± 1.11 L/kg for d-methylphenidate and 1.80 ± 0.91 L/kg for l-methylphenidate.
      3. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:8e97c9f3-956c-416a-a7c2-68bb92053ce5 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The volume of distribution was 2.65 ± 1.11L/kg for d-methylphenidate and 1.80 ± 0.91L/kg for l- methylphenidate.
      4. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:ed004cf0-eb23-43d2-96dc-20c4ad63824f (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The volume of distribution was 2.65 ± 1.11 L/kg for d-methylphenidate and 1.80 ± 0.91 L/kg for l-methylphenidate.
      5. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:be59f8b4-7842-42cc-9559-bfa747f0baa5 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The volume of distribution was 2.65 ± 1.11 L/kg for d- methylphenidate and 1.80 ± 0.91 L/kg for l- methylphenidate.
      6. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:2cf1b26b-199d-4c7f-ab64-4805a9def2cc (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The volume of distribution was 2.65 ± 1.11 L/kg for d-methylphenidate and 1.80 ± 0.91 L/kg for l-methylphenidate.
      7. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:35be77db-fbe3-487e-a220-a08a11aaec28 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The volume of distribution was 2.65 ± 1.11 L/kg for d-methylphenidate and 1.80 ± 0.91 L/kg for l -methylphenidate.
      8. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:e45c75dc-d381-475b-b649-a871c8a36e60 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The volume of distribution was 2.65 ± 1.11 L/kg for d- methylphenidate and 1.80 ± 0.91 L/kg for l- methylphenidate.
      9. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:e5db854a-1c77-4faf-9e60-daf9c9b6cfa0 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The volume of distribution was 2.65 ± 1.11 L/kg for d- methylphenidate and 1.80 ± 0.91 L/kg for l-methylphenidate.
      10. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:10aa0dc0-bd0e-4927-a19a-8722d78ad67d (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The volume of distribution was 2.65 ± 1.11 L/kg for d- methylphenidate and 1.80 ± 0.91 L/kg for l- methylphenidate.
      11. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:298fb86d-7d94-49e1-b743-3e7801122422 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The volume of distribution was 2.65 ± 1.11 L/kg for d-methylphenidate and 1.80 ± 0.91 L/kg for l-methylphenidate.
      12. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:ec8a8896-077d-4dee-9e10-97172512c5ed (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The volume of distribution was 2.65 ± 1.11 L/kg for d- methylphenidate and 1.80 ± 0.91 L/kg for l- methylphenidate.
      13. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:11f4ec97-ed86-48b5-af3a-446b882294cb (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The volume of distribution was 2.65 ± 1.11 L/kg for d-methylphenidate and 1.80 ± 0.91 L/kg for l -methylphenidate.
      14. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:1da9dc9e-7e8e-457a-93d4-9c2aee434e69 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The volume of distribution was 2.65 ± 1.11 L/kg for d-methylphenidate and 1.80 ± 0.91 L/kg for l -methylphenidate.
      15. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:981a2ad8-33f7-4678-9162-9df9685bd4a6 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The volume of distribution was 2.65 ± 1.11 L/kg for d-methylphenidate and 1.80 ± 0.91 L/kg for l-methylphenidate.
      16. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:c614cf55-b462-4f7e-b19c-6d22a47e509f (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The volume of distribution was 2.65 ± 1.11 L/kg for d-methylphenidate and 1.80 ± 0.91 L/kg for l -methylphenidate.
      17. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:1c7d7e6c-4e96-4d18-8dca-203ef50766ec (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The volume of distribution was 2.65 ± 1.11 L/kg for d -methylphenidate and 1.80 ± 0.91 L/kg for l -methylphenidate.
      18. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:e5cb0740-813f-4dce-8c29-d7680c66e77c (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The volume of distribution was 2.65 ± 1.11 L/kg for d-methylphenidate and 1.80 ± 0.91 L/kg for l-methylphenidate.
      19. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:83e70f8f-18dd-45fc-8bc5-4b8f7f23439e (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The volume of distribution was 2.65 ± 1.11 L/kg for d-methylphenidate and 1.80 ± 0.91 L/kg for l-methylphenidate.
      20. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:238ff743-4f25-43a3-87ac-6559d12a9d49 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The volume of distribution was 2.65 ± 1.11 L/kg for d- methylphenidate and 1.80 ± 0.91 L/kg for l- methylphenidate.
      21. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:effd952d-ac94-47bb-b107-589a4934dcca (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The volume of distribution was 2.65 ± 1.11 L/kg for d-methylphenidate and 1.80 ± 0.91 L/kg for l-methylphenidate.
      22. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:9beb136f-020b-4631-b989-c1d26a9846f7 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The volume of distribution was 2.65 ± 1.11 L/kg for d-methylphenidate and 1.80 ± 0.91 L/kg for l -methylphenidate.
      23. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:13a17c5a-bba7-4c5a-a4f9-2141bcdffa1a (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The volume of distribution was 2.65 ± 1.11 L/kg for d-methylphenidate and 1.80 ± 0.91 L/kg for l -methylphenidate.
      24. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:ea5a6d4e-60ba-46f3-b314-3c7a970b377d (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The volume of distribution was 2.65 ± 1.11 L/kg for d-methylphenidate and 1.80 ± 0.91 L/kg for l-methylphenidate.
      25. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:9e3c22d9-71d9-46a7-b315-8021c94c4bec (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The volume of distribution was 2.65 ± 1.11 L/kg for d-methylphenidate and 1.80 ± 0.91 L/kg for l-methylphenidate.
      26. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:27ea91ad-f64e-43d7-ab10-6f988bca5379 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The volume of distribution was 2.65 ± 1.11 L/kg for d-methylphenidate and 1.8 ± 0.91 L/kg for l-methylphenidate.
      27. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:57fd619e-687d-403c-a77a-3dc3a1bab65a (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The volume of distribution was 2.65 ± 1.11 L/kg for d-methylphenidate and 1.80 ± 0.91 L/kg for l-methylphenidate.
      28. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:29f06562-6b6a-4ca6-b62e-d08a45fb3dd4 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The volume of distribution was 2.65 ± 1.11 L/kg for d- methylphenidate and 1.80 ± 0.91 L/kg for l- methylphenidate.
      29. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:d6fb2750-cdab-4749-ba0d-7534840a5892 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The volume of distribution was 2.65 ± 1.11 L/kg for d-methylphenidate and 1.80 ± 0.91 L/kg for l -methylphenidate.
      30. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:ad3a3865-952e-46cf-8387-1228e2375312 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The volume of distribution was 2.65 ± 1.11 L/kg for d-methylphenidate and 1.80 ± 0.91 L/kg for l-methylphenidate.
      31. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:5fa3da25-13aa-4ee3-acf5-cd505f4688d0 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The volume of distribution was 2.65 ± 1.11 L/kg for d-methylphenidate and 1.80 ± 0.91 L/kg for l-methylphenidate.
      32. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:94dc74d4-b4ef-45bc-b502-54ec692e9bd5 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The volume of distribution was 2.65 ± 1.11 L/kg for d- methylphenidate and 1.80 ± 0.91 L/kg for l- methylphenidate.
      33. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:4f3c91e6-4576-4326-bdab-7d8fb7c09bb8 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The volume of distribution was 2.65 ± 1.11 L/kg for d-methylphenidate and 1.80 ± 0.91 L/kg for l-methylphenidate.
      34. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:b77128b3-fce4-4bee-bdad-5fe4af9d612d (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The volume of distribution was 2.65 ± 1.11 L/kg for d-methylphenidate and 1.80 ± 0.91 L/kg for l -methylphenidate.
      35. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:44386394-d2a3-4483-abe1-6c5c634cc501 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The volume of distribution was 2.65 ± 1.11 L/kg for d-methylphenidate and 1.80 ± 0.91 L/kg for l-methylphenidate.
      36. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:eb9b7377-d918-43fb-8e82-d14c85ed64a8 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The volume of distribution was 2.65 ± 1.11 L/kg for d-methylphenidate and 1.80 ± 0.91 L/kg for l-methylphenidate.
      37. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:371346d1-ac7e-491c-a010-ad29cb3d567a (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The volume of distribution was 2.65 ± 1.11 L/kg for d-methylphenidate and 1.80 ± 0.91 L/kg for l -methylphenidate.
      38. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:5a22dd9b-9b48-4c96-8b20-0d20131521dc (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The volume of distribution was 2.65 ± 1.11 L/kg for d -methylphenidate and 1.80 ± 0.91 L/kg for l -methylphenidate.
      39. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:778190da-1528-4def-94bf-ee23ee5268a5 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The volume of distribution was 2.65 ± 1.11 L/kg for d-methylphenidate and 1.80 ± 0.91 L/kg for l- methylphenidate.
      40. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:4cc16009-44ad-4055-ac76-efa282f1ff47 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The volume of distribution was 2.65 ± 1.11 L/kg for d-methylphenidate and 1.80 ± 0.91 L/kg for l -methylphenidate.
      41. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:034fb7cd-e183-475e-8beb-64fd88facc8f (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The volume of distribution was 2.65 ± 1.11 L/kg for d- methylphenidate and 1.80 ± 0.91 L/kg for l-methylphenidate.
      42. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:b9c31526-d486-433c-9b3c-7a12765afe94 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The volume of distribution was 2.65 ± 1.11 L/kg for d-methylphenidate and 1.80 ± 0.91 L/kg for l-methylphenidate.
      43. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:c0bf0835-6a2f-4067-a158-8b86c4b0668a (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The volume of distribution was 2.65 ± 1.11 L/kg for d-methylphenidate and 1.80 ± 0.91 L/kg for l -methylphenidate.
      44. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:1f8983ce-71b8-4c62-830d-e4692ddededa (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The volume of distribution was 2.65 ± 1.11 L/kg for d-methylphenidate and 1.80 ± 0.91 L/kg for l-methylphenidate.
      45. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:1bf37f9f-29cf-4b09-9c81-eb369e35a042 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The volume of distribution was 2.65 ± 1.11 L/kg for d-methylphenidate and 1.80 ± 0.91 L/kg for l-methylphenidate Elimination The systemic clearance is 0.40 ± 0.12 L/h/kg for d-methylphenidate and 0.73 ± 0.28 L/h/kg for l- methylphenidate.
      46. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:9e11e093-4ff3-4bed-8fe9-3ee460b47303 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The volume of distribution was 2.65 ± 1.11 L/kg for d-methylphenidate and 1.80 ± 0.91 L/kg for l-methylphenidate.
      47. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:ec3d9304-13bc-4f0b-bf14-1a1ea824bd91 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The volume of distribution was 2.65 ± 1.11 L/kg for d- methylphenidate and 1.80 ± 0.91 L/kg for l- methylphenidate.
      48. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:c87a2000-b75c-41df-8497-7e00a9b41ad4 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The volume of distribution was 2.65 ± 1.11 L/kg for d-methylphenidate and 1.80 ± 0.91 L/kg for l -methylphenidate.
      49. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:e817377f-bc72-415a-acd2-7136746b2479 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The volume of distribution was 2.65 ± 1.11 L/kg for d-methylphenidate and 1.80 ± 0.91 L/kg for l-methylphenidate.
      50. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:d8c14df4-ac05-d69d-9308-58a51d568329 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The volume of distribution was 2.65 ± 1.11 L/kg for d- methylphenidate and 1.80 ± 0.91 L/kg for l-methylphenidate.
      51. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:1a89b390-0cd5-45cb-9e70-20de44652c56 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The volume of distribution was 2.65 ± 1.11 L/kg for d -methylphenidate and 1.80 ± 0.91 L/kg for l -methylphenidate.
      52. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:45d33807-88b2-4b42-9c86-e5b05d7adec1 (opens source in a new tab)

        Methylphenidate label

        Version not recorded · Effective date not recorded

        The volume of distribution was 2.65 ± 1.11 L/kg for d-methylphenidate and 1.8 ± 0.91 L/kg for l-methylphenidate.
  10. Projected row 980

    Medicine slug
    metoclopramide
    Compared field
    bioavailability
    Comparison state
    agree
    Reason codes
    • COMPATIBLE_VALUES_OVERLAP
    Documents examined
    66
    Source count
    65
    Agreement rate
    1
    Recorded readings
    1. 80%

      Numeric value
      80
      Unit
      %
      Source records
      65

      Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.

      Show all 65 source records
      1. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:7cd1dc35-2fb2-4f1d-8769-24c3c3aa34fa (opens source in a new tab)

        Metoclopramide label

        Version not recorded · Effective date not recorded

        Absorption Relative to an intravenous dose of 20 mg, the absolute oral bioavailability of metoclopramide was 80% ± 15.5% as demonstrated in a crossover study of 18 subjects.
      2. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:b16ad17c-eeea-407e-91e4-36506e9aa698 (opens source in a new tab)

        Metoclopramide label

        Version not recorded · Effective date not recorded

        Increased rate of stomach emptying was observed with single oral doses of 10 mg. 12.3 Pharmacokinetics Absorption Relative to an intravenous dose of 20 mg, the absolute bioavailability of oral metoclopramide is 80% ± 15.5% as demonstrated in a crossover study of 18 subjects.
      3. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:dc364325-dd39-4259-a348-3760eccdca4b (opens source in a new tab)

        Metoclopramide label

        Version not recorded · Effective date not recorded

        Relative to intravenous dose of 20 mg, the absolute oral bioavailability of metoclopramide is 80% ± 15.5% as demonstrated in a crossover study of 18 subjects.
      4. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:7678bcd5-1071-0a9b-e053-2a91aa0a3853 (opens source in a new tab)

        Metoclopramide label

        Version not recorded · Effective date not recorded

        Relative to an intravenous dose of 20 mg, the absolute oral bioavailability of metoclopramide is 80% ± 15.5% as demonstrated in a crossover study of 18 subjects.
      5. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:94e5acdf-f19c-749a-e053-2995a90ae451 (opens source in a new tab)

        Metoclopramide label

        Version not recorded · Effective date not recorded

        Relative to an intravenous dose of 20 mg, the absolute oral bioavailability of metoclopramide is 80% ± 15.5% as demonstrated in a crossover study of 18 subjects.
      6. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:4e12e98a-06fe-4b3c-bb64-f2701e195c74 (opens source in a new tab)

        Metoclopramide label

        Version not recorded · Effective date not recorded

        Relative to an intravenous dose of 20 mg, the absolute oral bioavailability of metoclopramide is 80% ±15.5% as demonstrated in a crossover study of 18 subjects.
      7. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:c4ab34f2-25e6-47bd-9dde-1f4baf469f0d (opens source in a new tab)

        Metoclopramide label

        Version not recorded · Effective date not recorded

        Relative to intravenous dose of 20 mg, the absolute oral bioavailability of metoclopramide is 80% ± 15.5% as demonstrated in a crossover study of 18 subjects.
      8. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:5345a125-0cee-472e-e063-6394a90aeb21 (opens source in a new tab)

        Metoclopramide label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics Absorption Relative to an intravenous dose of 20 mg, the absolute bioavailability of oral metoclopramide is 80% ± 15.5% as demonstrated in a crossover study of 18 subjects.
      9. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:697ec7b1-945a-4a31-b585-f051dc246165 (opens source in a new tab)

        Metoclopramide label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics Absorption Relative to an intravenous dose of 20 mg, the absolute bioavailability of oral metoclopramide is 80% ± 15.5% as demonstrated in a crossover study of 18 subjects.
      10. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:50a3cf38-66dc-4fa5-8a45-adf959c987ab (opens source in a new tab)

        Metoclopramide label

        Version not recorded · Effective date not recorded

        Relative to an intravenous dose of 20 mg, the absolute oral bioavailability of metoclopramide is 80% ± 15.5% as demonstrated in a crossover study of 18 subjects.
      11. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:ce367a41-89d3-45c2-aac2-36fce43062d0 (opens source in a new tab)

        Metoclopramide label

        Version not recorded · Effective date not recorded

        Relative to an intravenous dose of 20 mg, the absolute oral bioavailability of metoclopramide is 80% ± 15.5% as demonstrated in a crossover study of 18 subjects.
      12. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:917494a9-cff1-4ee6-9523-e112120373c5 (opens source in a new tab)

        Metoclopramide label

        Version not recorded · Effective date not recorded

        Relative to an intravenous dose of 20 mg, the absolute oral bioavailability of metoclopramide is 80% ± 15.5% as demonstrated in a crossover study of 18 subjects.
      13. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:14114420-fee0-4850-b99e-cdb5f421cd33 (opens source in a new tab)

        Metoclopramide label

        Version not recorded · Effective date not recorded

        Relative to an intravenous dose of 20 mg, the absolute oral bioavailability of metoclopramide is 80% ±15.5% as demonstrated in a crossover study of 18 subjects.
      14. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:4046830f-4b87-5e6e-e063-6394a90aeeb8 (opens source in a new tab)

        Metoclopramide label

        Version not recorded · Effective date not recorded

        Relative to an intravenous dose of 20 mg, the absolute oral bioavailability of metoclopramide is 80% ± 15.5% as demonstrated in a crossover study of 18 subjects.
      15. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:373ba08b-33ad-49fc-28a7-928e89a65314 (opens source in a new tab)

        Metoclopramide label

        Version not recorded · Effective date not recorded

        Relative to an intravenous dose of 20 mg, the absolute oral bioavailability of metoclopramide is 80% ± 15.5% as demonstrated in a crossover study of 18 subjects.
      16. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:e15905e0-e0f6-4c8b-ac19-59724d6c4bf0 (opens source in a new tab)

        Metoclopramide label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics Absorption Relative to an intravenous dose of 20 mg, the absolute bioavailability of oral metoclopramide is 80% ± 15.5% as demonstrated in a crossover study of 18 subjects.
      17. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:31da0c8b-8171-4bd2-9832-12ba85e36b37 (opens source in a new tab)

        Metoclopramide label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics Absorption Relative to an intravenous dose of 20 mg, the absolute bioavailability of oral metoclopramide is 80% ± 15.5% as demonstrated in a crossover study of 18 subjects.
      18. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:46dcafbc-9d50-316a-e054-00144ff88e88 (opens source in a new tab)

        Metoclopramide label

        Version not recorded · Effective date not recorded

        Relative to an intravenous dose of 20 mg, the absolute oral bioavailability of metoclopramide is 80% ± 15.5% as demonstrated in a crossover study of 18 subjects.
      19. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:e34fea34-5fc5-4200-bc9d-f5e558023630 (opens source in a new tab)

        Metoclopramide label

        Version not recorded · Effective date not recorded

        Relative to an intravenous dose of 20 mg, the absolute oral bioavailability of metoclopramide is 80% ±15.5% as demonstrated in a crossover study of 18 subjects.
      20. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:de55c133-eb08-4a35-91a2-5dc093027397 (opens source in a new tab)

        Metoclopramide label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics Absorption Relative to an intravenous dose of 20 mg, the absolute bioavailability of oral metoclopramide is 80% ± 15.5% as demonstrated in a crossover study of 18 subjects.
      21. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:cccf04bd-7463-40b8-a41f-cb1093c358d7 (opens source in a new tab)

        Metoclopramide label

        Version not recorded · Effective date not recorded

        Relative to an intravenous dose of 20 mg, the absolute oral bioavailability of metoclopramide is 80% ± 15.5% as demonstrated in a crossover study of 18 subjects.
      22. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:5345905d-18b0-1e42-e063-6394a90af745 (opens source in a new tab)

        Metoclopramide label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics Absorption Relative to an intravenous dose of 20 mg, the absolute bioavailability of oral metoclopramide is 80% ± 15.5% as demonstrated in a crossover study of 18 subjects.
      23. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:67024bbc-65d1-428d-a807-46647038daf6 (opens source in a new tab)

        Metoclopramide label

        Version not recorded · Effective date not recorded

        Relative to an intravenous dose of 20 mg, the absolute oral bioavailability of metoclopramide is 80% ±15.5% as demonstrated in a crossover study of 18 subjects.
      24. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:5d7cd5a0-4a84-4084-e053-2a91aa0a686f (opens source in a new tab)

        Metoclopramide label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics Absorption Relative to an intravenous dose of 20 mg, the absolute bioavailability of oral metoclopramide is 80% ± 15.5% as demonstrated in a crossover study of 18 subjects.
      25. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:3ce3245f-7021-5135-e063-6394a90a7d95 (opens source in a new tab)

        Metoclopramide label

        Version not recorded · Effective date not recorded

        Relative to an intravenous dose of 20 mg, the absolute oral bioavailability of metoclopramide is 80% ±15.5% as demonstrated in a crossover study of 18 subjects.
      26. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:7eeaa7bc-c94f-47d0-94e5-e35ccadca19e (opens source in a new tab)

        Metoclopramide label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics Absorption Relative to an intravenous dose of 20 mg, the absolute bioavailability of oral metoclopramide is 80% ± 15.5% as demonstrated in a crossover study of 18 subjects.
      27. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:3cd4b274-6176-4e5b-9765-4f50763bd58f (opens source in a new tab)

        Metoclopramide label

        Version not recorded · Effective date not recorded

        Relative to an intravenous dose of 20 mg, the absolute oral bioavailability of metoclopramide is 80% ± 15.5% as demonstrated in a crossover study of 18 subjects.
      28. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:5d31d815-50fa-4e78-8ebd-affc2514ce78 (opens source in a new tab)

        Metoclopramide label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics Absorption Relative to an intravenous dose of 20 mg, the absolute bioavailability of oral metoclopramide is 80% ± 15.5% as demonstrated in a crossover study of 18 subjects.
      29. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:4524146c-f588-083b-e063-6294a90ac977 (opens source in a new tab)

        Metoclopramide label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics Absorption Relative to an intravenous dose of 20 mg, the absolute bioavailability of oral metoclopramide is 80% ± 15.5% as demonstrated in a crossover study of 18 subjects.
      30. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:79754097-4514-297e-e053-2991aa0a4804 (opens source in a new tab)

        Metoclopramide label

        Version not recorded · Effective date not recorded

        Relative to an intravenous dose of 20 mg, the absolute oral bioavailability of metoclopramide is 80% ± 15.5% as demonstrated in a crossover study of 18 subjects.
      31. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:40cf021d-5f2a-055c-e054-00144ff88e88 (opens source in a new tab)

        Metoclopramide label

        Version not recorded · Effective date not recorded

        Relative to an intravenous dose of 20 mg, the absolute oral bioavailability of metoclopramide is 80% ± 15.5% as demonstrated in a crossover study of 18 subjects.
      32. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:447dbb34-7903-4e6a-be31-48a0b0e0d2f5 (opens source in a new tab)

        Metoclopramide label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics Absorption Relative to an intravenous dose of 20 mg, the absolute bioavailability of oral metoclopramide is 80% ± 15.5% as demonstrated in a crossover study of 18 subjects.
      33. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:f50c8fb4-23c4-4762-95bb-e4ca7b289a4d (opens source in a new tab)

        Metoclopramide label

        Version not recorded · Effective date not recorded

        Relative to an intravenous dose of 20 mg, the absolute oral bioavailability of metoclopramide is 80% ± 15.5% as demonstrated in a crossover study of 18 subjects.
      34. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:58b3666f-ac0f-811e-e063-6394a90a8e04 (opens source in a new tab)

        Metoclopramide label

        Version not recorded · Effective date not recorded

        Increased rate of stomach emptying was observed with single oral doses of 10 mg. 12.3 Pharmacokinetics Absorption Relative to an intravenous dose of 20 mg, the absolute bioavailability of oral metoclopramide is 80% ± 15.5% as demonstrated in a crossover study of 18 subjects.
      35. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:595439ae-cf01-821c-e063-6294a90af16a (opens source in a new tab)

        Metoclopramide label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics Absorption Relative to an intravenous dose of 20 mg, the absolute bioavailability of oral metoclopramide is 80% ± 15.5% as demonstrated in a crossover study of 18 subjects.
      36. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:797aad80-0597-42f8-99d5-39de180c3b5a (opens source in a new tab)

        Metoclopramide label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics Absorption Relative to an intravenous dose of 20 mg, the absolute bioavailability of oral metoclopramide is 80% ± 15.5% as demonstrated in a crossover study of 18 subjects.
      37. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:d163182b-582d-df59-e053-2995a90a300b (opens source in a new tab)

        Metoclopramide label

        Version not recorded · Effective date not recorded

        Relative to an intravenous dose of 20 mg, the absolute oral bioavailability of metoclopramide is 80% ± 15.5% as demonstrated in a crossover study of 18 subjects.
      38. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:264c4f48-51f4-458f-9e61-1adafdf604fc (opens source in a new tab)

        Metoclopramide label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics Absorption Relative to an intravenous dose of 20 mg, the absolute bioavailability of oral metoclopramide is 80% ± 15.5% as demonstrated in a crossover study of 18 subjects.
      39. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:84ec68c1-efa0-4ed2-9fae-d0cc17b0a6b4 (opens source in a new tab)

        Metoclopramide label

        Version not recorded · Effective date not recorded

        Relative to an intravenous dose of 20 mg, the absolute oral bioavailability of metoclopramide is 80% ±15.5% as demonstrated in a crossover study of 18 subjects.
      40. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:6637cb78-d50a-4dbf-8fb7-b1b5102c5c5f (opens source in a new tab)

        Metoclopramide label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics Absorption Relative to an intravenous dose of 20 mg, the absolute bioavailability of oral metoclopramide is 80% ± 15.5% as demonstrated in a crossover study of 18 subjects.
      41. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:5645a752-8868-4b51-8b59-48bb4276d763 (opens source in a new tab)

        Metoclopramide label

        Version not recorded · Effective date not recorded

        Relative to an intravenous dose of 20 mg, the absolute oral bioavailability of metoclopramide is 80% ± 15.5% as demonstrated in a crossover study of 18 subjects.
      42. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:dc4a13f8-1e9b-4c75-82c0-bcd11f0a9a66 (opens source in a new tab)

        Metoclopramide label

        Version not recorded · Effective date not recorded

        Relative to an intravenous dose of 20 mg, the absolute oral bioavailability of metoclopramide is 80% ± 15.5% as demonstrated in a crossover study of 18 subjects.
      43. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:0034a97a-fb05-418a-a234-de278907cd2a (opens source in a new tab)

        Metoclopramide label

        Version not recorded · Effective date not recorded

        Relative to an intravenous dose of 20 mg, the absolute oral bioavailability of metoclopramide is 80% ±15.5% as demonstrated in a crossover study of 18 subjects.
      44. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:58e70a1b-ac93-ff1d-e063-6394a90aa2da (opens source in a new tab)

        Metoclopramide label

        Version not recorded · Effective date not recorded

        Increased rate of stomach emptying was observed with single oral doses of 10 mg. 12.3 Pharmacokinetics Absorption Relative to an intravenous dose of 20 mg, the absolute bioavailability of oral metoclopramide is 80% ± 15.5% as demonstrated in a crossover study of 18 subjects.
      45. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:74358569-7a24-4a59-a7fc-500d2341d6cb (opens source in a new tab)

        Metoclopramide label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics Absorption Relative to an intravenous dose of 20 mg, the absolute bioavailability of oral metoclopramide is 80% ± 15.5% as demonstrated in a crossover study of 18 subjects.
      46. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:23f11d3c-1529-4bb6-a61e-e4bab1a3e98e (opens source in a new tab)

        Metoclopramide label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics Absorption Relative to an intravenous dose of 20 mg, the absolute bioavailability of oral metoclopramide is 80% ± 15.5% as demonstrated in a crossover study of 18 subjects.
      47. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:55b3fecb-f60c-474b-9530-915b0e68bf85 (opens source in a new tab)

        Metoclopramide label

        Version not recorded · Effective date not recorded

        Relative to an intravenous dose of 20 mg, the absolute oral bioavailability of metoclopramide is 80% ± 15.5% as demonstrated in a crossover study of 18 subjects.
      48. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:1ecab710-8b7d-4903-80a8-de66562be55a (opens source in a new tab)

        Metoclopramide label

        Version not recorded · Effective date not recorded

        Relative to an intravenous dose of 20 mg, the absolute oral bioavailability of metoclopramide is 80% ± 15.5% as demonstrated in a crossover study of 18 subjects.
      49. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:45250bbc-d079-c362-e063-6294a90a56e0 (opens source in a new tab)

        Metoclopramide label

        Version not recorded · Effective date not recorded

        Increased rate of stomach emptying was observed with single oral doses of 10 mg. 12.3 Pharmacokinetics Absorption Relative to an intravenous dose of 20 mg, the absolute bioavailability of oral metoclopramide is 80% ± 15.5% as demonstrated in a crossover study of 18 subjects.
      50. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:c4828095-94e0-4f71-901c-93837974c658 (opens source in a new tab)

        Metoclopramide label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics Absorption Relative to an intravenous dose of 20 mg, the absolute bioavailability of oral metoclopramide is 80% ± 15.5% as demonstrated in a crossover study of 18 subjects.
      51. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:49eb807b-fa34-3d84-e063-6394a90acfcf (opens source in a new tab)

        Metoclopramide label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics Absorption Relative to an intravenous dose of 20 mg, the absolute bioavailability of oral metoclopramide is 80% ± 15.5% as demonstrated in a crossover study of 18 subjects.
      52. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:9530014b-c266-4015-9195-9f100d67317b (opens source in a new tab)

        Metoclopramide label

        Version not recorded · Effective date not recorded

        Relative to an intravenous dose of 20 mg, the absolute oral bioavailability of metoclopramide is 80% ±15.5% as demonstrated in a crossover study of 18 subjects.
      53. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:f2b732ab-b859-7252-e053-2995a90af0d8 (opens source in a new tab)

        Metoclopramide label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics Absorption Relative to an intravenous dose of 20 mg, the absolute bioavailability of oral metoclopramide is 80% ± 15.5% as demonstrated in a crossover study of 18 subjects.
      54. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:15d616d7-2f4c-4882-a03c-fcc86c18f5f8 (opens source in a new tab)

        Metoclopramide label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics Absorption Relative to an intravenous dose of 20 mg, the absolute bioavailability of oral metoclopramide is 80% ± 15.5% as demonstrated in a crossover study of 18 subjects.
      55. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:146803a1-199d-4789-b128-e974bdd03322 (opens source in a new tab)

        Metoclopramide label

        Version not recorded · Effective date not recorded

        Relative to an intravenous dose of 20 mg, the absolute oral bioavailability of metoclopramide is 80% ± 15.5% as demonstrated in a crossover study of 18 subjects.
      56. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:6f0a13cc-9346-4f4a-9a0d-b725045b01aa (opens source in a new tab)

        Metoclopramide label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics Absorption Relative to an intravenous dose of 20 mg, the absolute bioavailability of oral metoclopramide is 80% ± 15.5% as demonstrated in a crossover study of 18 subjects.
      57. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:3f2b17ea-c265-0cd4-e063-6294a90a9d88 (opens source in a new tab)

        Metoclopramide label

        Version not recorded · Effective date not recorded

        Relative to an intravenous dose of 20 mg, the absolute oral bioavailability of metoclopramide is 80% ± 15.5% as demonstrated in a crossover study of 18 subjects.
      58. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:998f1782-bbfa-469b-9fe1-c612e8588f70 (opens source in a new tab)

        Metoclopramide label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics Absorption Relative to an intravenous dose of 20 mg, the absolute bioavailability of oral metoclopramide is 80% ± 15.5% as demonstrated in a crossover study of 18 subjects.
      59. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:41d9ee49-d434-5f9f-e063-6294a90afe0b (opens source in a new tab)

        Metoclopramide label

        Version not recorded · Effective date not recorded

        Relative to an intravenous dose of 20 mg, the absolute oral bioavailability of metoclopramide is 80% ± 15.5% as demonstrated in a crossover study of 18 subjects.
      60. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:ff067ac5-6efc-3e86-e6d5-590b2779491c (opens source in a new tab)

        Metoclopramide label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics Absorption Relative to an intravenous dose of 20 mg, the absolute bioavailability of oral metoclopramide is 80% ± 15.5% as demonstrated in a crossover study of 18 subjects.
      61. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:3cc8ca5b-8b71-4c77-a181-9ce154597b9a (opens source in a new tab)

        Metoclopramide label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics Absorption Relative to an intravenous dose of 20 mg, the absolute bioavailability of oral metoclopramide is 80% ± 15.5% as demonstrated in a crossover study of 18 subjects.
      62. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:cc739885-e10e-4bcb-a781-c726c518f3d1 (opens source in a new tab)

        Metoclopramide label

        Version not recorded · Effective date not recorded

        Relative to an intravenous dose of 20 mg, the absolute oral bioavailability of metoclopramide is 80% ± 15.5% as demonstrated in a crossover study of 18 subjects.
      63. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:548e83bc-898f-6b16-e063-6294a90a1755 (opens source in a new tab)

        Metoclopramide label

        Version not recorded · Effective date not recorded

        Increased rate of stomach emptying was observed with single oral doses of 10 mg. 12.3 Pharmacokinetics Absorption Relative to an intravenous dose of 20 mg, the absolute bioavailability of oral metoclopramide is 80% ± 15.5% as demonstrated in a crossover study of 18 subjects.
      64. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:4ab8ddab-8226-4b5a-8774-308ed49d6bc4 (opens source in a new tab)

        Metoclopramide label

        Version not recorded · Effective date not recorded

        12.3 Pharmacokinetics Absorption Relative to an intravenous dose of 20 mg, the absolute bioavailability of oral metoclopramide is 80% ± 15.5% as demonstrated in a crossover study of 18 subjects.
      65. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:c143e210-4ce7-44e5-b1e2-bf0e6bfde485 (opens source in a new tab)

        Metoclopramide label

        Version not recorded · Effective date not recorded

        Increased rate of stomach emptying was observed with single oral doses of 10 mg. 12.3 Pharmacokinetics Absorption Relative to an intravenous dose of 20 mg, the absolute bioavailability of oral metoclopramide is 80% ± 15.5% as demonstrated in a crossover study of 18 subjects.

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