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Public dataset

Recorded source agreement and disagreement

Show whether sources print one normalized reading, have incompatible units, lack structured comparison context, or contain a context-matched numeric difference.

What this does not mean: agree can mean only that sources print the same normalized reading; it is not clinical-context equivalence, independent replication, or proof. differ requires matching structured context and disjoint comparable values. not_comparable and insufficient_context are not disagreement.
Public rows
1,681
Generated
Schema version
source-consensus/2

Coverage

What this run contains

Compared medicine fields
1,681
Agree
1,282
Differ
0
Not comparable
12
Insufficient context
387
Fields represented
5
bioavailability, halfLife, proteinBinding, tMax, volumeOfDistribution

Method

How the rows were made

  1. Deterministic rules normalize recorded pharmacokinetic readings and compare only like-for-like values.
  2. One normalized printed reading may be agree even when clinical context was not extracted; this reports printed-reading agreement only.
  3. Distinct readings may differ only when their units and denominators are comparable and one matching, non-placeholder population/formulation context was structurally extracted. Otherwise they are insufficient_context.
  4. not_comparable preserves incompatible units or denominators instead of guessing. insufficient_context preserves missing or non-matching structured context instead of manufacturing agreement or disagreement.
  5. The agreement rate describes the distribution of recorded source readings; it is not a probability that a value is true.
  6. Every distinct printed reading retains its unit, population context, source count, and complete source records. The API paginates field rows, never child readings or sources.
  7. documentsExamined is every matching single-substance archive document inspected for that medicine. The generator has no document, reading, or source ceiling, so there is no hidden available-versus-retained remainder.

Limits

Read these before using a row

  • Current label parsing does not structurally extract population or formulation context. Distinct otherwise-comparable readings are therefore insufficient_context, never differ; agree may mean printed-reading agreement only. Source records are complete but are not independent-experiment counts.
  • The current deterministic parser does not structurally extract population or formulation context from these sentences. It records that context as unknown and cannot publish distinct same-unit readings as differ.
  • Neither reading is marked wrong. Population, formulation, route, and other unextracted context may explain the printed difference.
  • Only the recorded fields and source documents in this snapshot are compared.
  • A source count is the number of retained source records in the row, not a count of independent experiments.

Provenance

Source examples

abacavir · bioavailability · agree

15 documents examined; 83% (Unknown: population and formulation context were not structurally extracted from this source sentence.)

FDA_LABEL:5676d391-f9a4-44be-9604-954b3d8d0e2b (opens source in a new tab)
The geometric mean absolute bioavailability of the tablet was 83%.

alemtuzumab · volumeOfDistribution · not_comparable

2 documents examined; 0.18 L/kg (Unknown: population and formulation context were not structurally extracted from this source sentence.); 14.1 L (Unknown: population and formulation context were not structurally extracted from this source sentence.)

FDA_LABEL:4f5f7255-7abc-4328-bd1a-ceaf139ef3e0 (opens source in a new tab)
Distribution After the last 30 mg dose, the mean volume of distribution at steady-state was 0.18 L/kg (range 0.1 to 0.4 L/kg).

abiraterone · halfLife · insufficient_context

31 documents examined; 12 ± 5 hours (Unknown: population and formulation context were not structurally extracted from this source sentence.); 18 hours (Unknown: population and formulation context were not structurally extracted from this source sentence.)

FDA_LABEL:c9eb9b46-f847-40a8-802c-a51b40406d5a (opens source in a new tab)
Elimination In patients with metastatic CRPC, the mean terminal half-life of abiraterone in plasma (mean ± SD) is 12 ± 5 hours.

Artifact used for this view: data/source-consensus.ndjson. The reader resolves the current run first and uses the checked-in compatibility run only when a current artifact is absent.

Schema

Fields in the public projection

FieldTypeMeaning
medicineSlugstringStable RNAWiki medicine route key.
fieldstringRecorded pharmacokinetic field being compared.
comparisonStatestringagree (printed-reading agreement), differ (context-matched comparable disjoint values), not_comparable (unit/denominator mismatch), or insufficient_context. Every state remains declared even when its current count is zero.
comparisonReasonsstring[]Deterministic codes explaining the state.
documentsExaminednumberRecorded source documents considered for the field.
sourceCountnumberRecorded source readings represented.
agreementRatenumberShare represented by the leading normalized printed-reading group; not a confidence score or clinical agreement probability.
readingsconsensus-reading[]Complete, untruncated reading groups. Each keeps the printed display, numeric value when parsed, unit, population context, source count, and every source identity, version/effective date or explicit absence, retrieval date, locator, safe link, and excerpt.

Reader

Search and filter the rows

Case-insensitive text search over the public fields named for this dataset.

Exact comparability state.

Exact recorded field key.

Clear

Showing 481490 of 1,681 matching rows. Filters and search terms remain attached when you move between pages or open the API view.

  1. Projected row 481

    Medicine slug
    doxycycline
    Compared field
    tMax
    Comparison state
    insufficient_context
    Reason codes
    • STRUCTURED_CONTEXT_MISSING
    Documents examined
    234
    Source count
    8
    Agreement rate
    0.875
    Recorded readings
    1. 3 hours

      Numeric value
      3
      Unit
      hours
      Source records
      7

      Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.

      Show all 7 source records
      1. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:0a18d4c7-9484-4d3e-b61b-e81fe63fefec (opens source in a new tab)

        Doxycycline label

        Version not recorded · Effective date not recorded

        tion of doxycycline hyclate delayed-release tablets, 200 mg to adult volunteers, average peak plasma doxycycline concentration (C max ) was 4.6 mcg/mL and 6.3 mcg/mL, respectively with median t max of 3 hours; the corresponding mean plasma concentration values 24 hours after single and multiple doses were 1.5 mcg/mL and 2.3 mcg/mL, respectively.
      2. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:f5ee43b2-d6ca-4819-a3d7-07f8421015d7 (opens source in a new tab)

        Doxycycline label

        Version not recorded · Effective date not recorded

        tion of doxycycline hyclate delayed-release tablets, 200 mg to adult volunteers, average peak plasma doxycycline concentration (C max ) was 4.6 mcg/mL and 6.3 mcg/mL, respectively with median t max of 3 hours; the corresponding mean plasma concentration values 24 hours after single and multiple doses were 1.5 mcg/mL and 2.3 mcg/mL, respectively.
      3. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:cd2ab9b8-9619-4199-8a5d-83377b3274d1 (opens source in a new tab)

        Doxycycline label

        Version not recorded · Effective date not recorded

        tion of doxycycline hyclate delayed-release tablets, 200 mg to adult volunteers, average peak plasma doxycycline concentration (C max ) was 4.6 mcg/mL and 6.3 mcg/mL, respectively with median t max of 3 hours; the corresponding mean plasma concentration values 24 hours after single and multiple doses were 1.5 mcg/mL and 2.3 mcg/mL, respectively.
      4. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:3ae4ca12-be39-46b9-bc4c-f8356776c175 (opens source in a new tab)

        Doxycycline label

        Version not recorded · Effective date not recorded

        tion of doxycycline hyclate delayed-release tablets, 200 mg to adult volunteers, average peak plasma doxycycline concentration (C max ) was 4.6 mcg/mL and 6.3 mcg/mL, respectively with median t max of 3 hours; the corresponding mean plasma concentration values 24 hours after single and multiple doses were 1.5 mcg/mL and 2.3 mcg/mL, respectively.
      5. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:c2b08332-3256-4658-965a-ede3d973a388 (opens source in a new tab)

        Doxycycline label

        Version not recorded · Effective date not recorded

        tion of doxycycline hyclate delayed-release tablets, 200 mg to adult volunteers, average peak plasma doxycycline concentration (C max ) was 4.6 mcg/mL and 6.3 mcg/mL, respectively with median t max of 3 hours; the corresponding mean plasma concentration values 24 hours after single and multiple doses were 1.5 mcg/mL and 2.3 mcg/mL, respectively.
      6. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:44ac5de1-c0c6-4d58-9a49-b2dae60ea921 (opens source in a new tab)

        Doxycycline label

        Version not recorded · Effective date not recorded

        tion of doxycycline hyclate delayed-release tablets, 200 mg to adult volunteers, average peak plasma doxycycline concentration (C max ) was 4.6 mcg/mL and 6.3 mcg/mL, respectively with median t max of 3 hours; the corresponding mean plasma concentration values 24 hours after single and multiple doses were 1.5 mcg/mL and 2.3 mcg/mL, respectively.
      7. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:4fa26176-a730-48ed-9659-e2f64212f418 (opens source in a new tab)

        Doxycycline label

        Version not recorded · Effective date not recorded

        Following single and multiple-dose administration of doxycycline hyclate delayed-release tablets, 200 mg to adult volunteers, average peak plasma doxycycline concentration (C max ) was 4.6 mcg/mL and 6.3 mcg/mL, respectively with median t max of 3 hours; the corresponding mean plasma concentration values 24 hours after single and multiple doses were 1.5 mcg/mL and 2.3 mcg/mL, respectively.
    2. 2.8 hours

      Numeric value
      2.8
      Unit
      hours
      Source records
      1

      Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.

      Show all 1 source records
      1. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:f9277bb8-982d-444d-9325-35d5c53a2d35 (opens source in a new tab)

        Doxycycline label

        Version not recorded · Effective date not recorded

        The Tmax was 2.8 hours.
  2. Projected row 482

    Medicine slug
    dronabinol
    Compared field
    halfLife
    Comparison state
    agree
    Reason codes
    • COMPATIBLE_VALUES_OVERLAP
    Documents examined
    9
    Source count
    9
    Agreement rate
    1
    Recorded readings
    1. 4 hours

      Numeric value
      4
      Unit
      hours
      Source records
      9

      Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.

      Show all 9 source records
      1. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:44205ae6-b86a-485c-baf6-233a2c878640 (opens source in a new tab)

        Dronabinol label

        Version not recorded · Effective date not recorded

        Published data showed an increase in the elimination half-life of pentobarbital by 4 hours when concomitantly dosed with dronabinol [see Warnings and Precautions (5.1) ] . 12.5 Pharmacogenomics Published data indicate a 2- to 3-fold higher dronabinol exposure in individuals carrying genetic variants associated with diminished CYP2C9 function.
      2. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:628f9609-6583-49be-be77-b64cfbc46fd7 (opens source in a new tab)

        Dronabinol label

        Version not recorded · Effective date not recorded

        Published data showed an increase in the elimination half-life of pentobarbital by 4 hours when concomitantly dosed with dronabinol [see Warnings and Precautions (5.1)] . 12 CLINICAL PHARMACOLOGY 12.1 Mechanism of Action Dronabinol is an orally active cannabinoid which has complex effects on the CNS, including central sympathomimetic activity.
      3. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:3cdcb4f5-5af9-4ff7-b535-2a5cf4c6da89 (opens source in a new tab)

        Dronabinol label

        Version not recorded · Effective date not recorded

        Published data showed an increase in the elimination half-life of pentobarbital by 4 hours when concomitantly dosed with dronabinol [see Warnings and Precautions ( 5.1 )] . 12 CLINICAL PHARMACOLOGY 12.1 Mechanism of Action Dronabinol is an orally active cannabinoid that has complex effects on the CNS, including central sympathomimetic activity.
      4. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:adb1801c-0fb5-4e16-b969-1db91230e0b9 (opens source in a new tab)

        Dronabinol label

        Version not recorded · Effective date not recorded

        Published data showed an increase in the elimination half-life of pentobarbital by 4 hours when concomitantly dosed with dronabinol [see Warnings and Precautions ( 5.1 )]. 12 CLINICAL PHARMACOLOGY 12.1 Mechanism of Action Dronabinol is an orally active cannabinoid which has complex effects on the CNS, including central sympathomimetic activity.
      5. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:fd8c5d57-0173-4f62-8ff0-d8147986a976 (opens source in a new tab)

        Dronabinol label

        Version not recorded · Effective date not recorded

        Published data showed an increase in the elimination half-life of pentobarbital by 4 hours when concomitantly dosed with dronabinol [see Warnings and Precautions ( 5.1 )]. 12 CLINICAL PHARMACOLOGY 12.1 Mechanism of Action Dronabinol is an orally active cannabinoid which has complex effects on the CNS, including central sympathomimetic activity.
      6. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:a7801c70-995d-46a2-91ee-141ef427c6b5 (opens source in a new tab)

        Dronabinol label

        Version not recorded · Effective date not recorded

        Published data showed an increase in the elimination half-life of pentobarbital by 4 hours when concomitantly dosed with dronabinol [see Warnings and Precautions ( 5.1 )] . 12 CLINICAL PHARMACOLOGY 12.1 Mechanism of Action Dronabinol is an orally active cannabinoid that has complex effects on the CNS, including central sympathomimetic activity.
      7. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:d0efeeec-640d-43c3-8f0a-d31324a11c68 (opens source in a new tab)

        Dronabinol label

        Version not recorded · Effective date not recorded

        Published data showed an increase in the elimination half-life of pentobarbital by 4 hours when concomitantly dosed with dronabinol [see Warnings and Precautions ( 5.1 )]. 12 CLINICAL PHARMACOLOGY 12.1 Mechanism of Action Dronabinol is an orally active cannabinoid which has complex effects on the CNS, including central sympathomimetic activity.
      8. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:495aabae-3597-49dc-a5af-e328bcd937b7 (opens source in a new tab)

        Dronabinol label

        Version not recorded · Effective date not recorded

        Published data showed an increase in the elimination half-life of pentobarbital by 4 hours when concomitantly dosed with dronabinol [see Warnings and Precautions ( 5.1 )] . 12 CLINICAL PHARMACOLOGY 12.1 Mechanism of Action Dronabinol is an orally active cannabinoid that has complex effects on the CNS, including central sympathomimetic activity.
      9. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:66f36fe0-9808-4b73-a99a-794d86ff0c1c (opens source in a new tab)

        Dronabinol label

        Version not recorded · Effective date not recorded

        Published data showed an increase in the elimination half-life of pentobarbital by 4 hours when concomitantly dosed with dronabinol [see Warnings and Precautions (5.1)] . abs 12.5 Pharmacogenomics Published data indicate a potentially 2-to 3-fold higher dronabinol exposure in individuals carrying genetic variants associated with diminished CYP2C9 function.
  3. Projected row 483

    Medicine slug
    dronabinol
    Compared field
    proteinBinding
    Comparison state
    agree
    Reason codes
    • COMPATIBLE_VALUES_OVERLAP
    Documents examined
    9
    Source count
    9
    Agreement rate
    1
    Recorded readings
    1. 97%

      Numeric value
      97
      Unit
      %
      Source records
      9

      Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.

      Show all 9 source records
      1. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:44205ae6-b86a-485c-baf6-233a2c878640 (opens source in a new tab)

        Dronabinol label

        Version not recorded · Effective date not recorded

        The plasma protein binding of dronabinol and its metabolites is approximately 97% [see Drug Interactions (7.3) ] .
      2. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:628f9609-6583-49be-be77-b64cfbc46fd7 (opens source in a new tab)

        Dronabinol label

        Version not recorded · Effective date not recorded

        The plasma protein binding of dronabinol and its metabolites is approximately 97% [see Drug Interactions (7.4)] .
      3. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:3cdcb4f5-5af9-4ff7-b535-2a5cf4c6da89 (opens source in a new tab)

        Dronabinol label

        Version not recorded · Effective date not recorded

        The plasma protein binding of dronabinol and its metabolites is approximately 97% [see Drug Interactions ( 7.3 )] .
      4. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:adb1801c-0fb5-4e16-b969-1db91230e0b9 (opens source in a new tab)

        Dronabinol label

        Version not recorded · Effective date not recorded

        The plasma protein binding of dronabinol and its metabolites is approximately 97% [see Drug Interactions ( 7.4 )].
      5. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:fd8c5d57-0173-4f62-8ff0-d8147986a976 (opens source in a new tab)

        Dronabinol label

        Version not recorded · Effective date not recorded

        The plasma protein binding of dronabinol and its metabolites is approximately 97% [see Drug Interactions ( 7.4 )].
      6. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:a7801c70-995d-46a2-91ee-141ef427c6b5 (opens source in a new tab)

        Dronabinol label

        Version not recorded · Effective date not recorded

        The plasma protein binding of dronabinol and its metabolites is approximately 97% [see Drug Interactions ( 7.3 )] .
      7. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:d0efeeec-640d-43c3-8f0a-d31324a11c68 (opens source in a new tab)

        Dronabinol label

        Version not recorded · Effective date not recorded

        The plasma protein binding of dronabinol and its metabolites is approximately 97% [see Drug Interactions ( 7.4) ].
      8. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:495aabae-3597-49dc-a5af-e328bcd937b7 (opens source in a new tab)

        Dronabinol label

        Version not recorded · Effective date not recorded

        The plasma protein binding of dronabinol and its metabolites is approximately 97% [see Drug Interactions ( 7.3 )] .
      9. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:66f36fe0-9808-4b73-a99a-794d86ff0c1c (opens source in a new tab)

        Dronabinol label

        Version not recorded · Effective date not recorded

        The plasma protein binding of dronabinol and its metabolites is approximately 97% [see Drug Interactions (7.4)] .
  4. Projected row 484

    Medicine slug
    dronabinol
    Compared field
    volumeOfDistribution
    Comparison state
    agree
    Reason codes
    • COMPATIBLE_VALUES_OVERLAP
    Documents examined
    9
    Source count
    9
    Agreement rate
    1
    Recorded readings
    1. 10 L/kg

      Numeric value
      10
      Unit
      L/kg
      Source records
      9

      Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.

      Show all 9 source records
      1. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:44205ae6-b86a-485c-baf6-233a2c878640 (opens source in a new tab)

        Dronabinol label

        Version not recorded · Effective date not recorded

        Distribution Dronabinol has an apparent volume of distribution of approximately 10 L/kg, because of its lipid solubility.
      2. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:628f9609-6583-49be-be77-b64cfbc46fd7 (opens source in a new tab)

        Dronabinol label

        Version not recorded · Effective date not recorded

        Distribution Dronabinol has an apparent volume of distribution of approximately 10 L/kg, because of its lipid solubility.
      3. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:3cdcb4f5-5af9-4ff7-b535-2a5cf4c6da89 (opens source in a new tab)

        Dronabinol label

        Version not recorded · Effective date not recorded

        Distribution Dronabinol has an apparent volume of distribution of approximately 10 L/kg, because of its lipid solubility.
      4. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:adb1801c-0fb5-4e16-b969-1db91230e0b9 (opens source in a new tab)

        Dronabinol label

        Version not recorded · Effective date not recorded

        Distribution Dronabinol has an apparent volume of distribution of approximately 10 L/kg, because of its lipid solubility.
      5. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:fd8c5d57-0173-4f62-8ff0-d8147986a976 (opens source in a new tab)

        Dronabinol label

        Version not recorded · Effective date not recorded

        Distribution Dronabinol has an apparent volume of distribution of approximately 10 L/kg, because of its lipid solubility.
      6. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:a7801c70-995d-46a2-91ee-141ef427c6b5 (opens source in a new tab)

        Dronabinol label

        Version not recorded · Effective date not recorded

        Distribution Dronabinol has an apparent volume of distribution of approximately 10 L/kg, because of its lipid solubility.
      7. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:d0efeeec-640d-43c3-8f0a-d31324a11c68 (opens source in a new tab)

        Dronabinol label

        Version not recorded · Effective date not recorded

        Distribution Dronabinol has an apparent volume of distribution of approximately 10 L/kg, because of its lipid solubility.
      8. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:495aabae-3597-49dc-a5af-e328bcd937b7 (opens source in a new tab)

        Dronabinol label

        Version not recorded · Effective date not recorded

        Distribution Dronabinol has an apparent volume of distribution of approximately 10 L/kg, because of its lipid solubility.
      9. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:66f36fe0-9808-4b73-a99a-794d86ff0c1c (opens source in a new tab)

        Dronabinol label

        Version not recorded · Effective date not recorded

        Distribution Dronabinol has an apparent volume of distribution of approximately 10 L/kg, because of its lipid solubility.
  5. Projected row 485

    Medicine slug
    dronedarone
    Compared field
    bioavailability
    Comparison state
    agree
    Reason codes
    • COMPATIBLE_VALUES_OVERLAP
    Documents examined
    2
    Source count
    2
    Agreement rate
    1
    Recorded readings
    1. 4%

      Numeric value
      4
      Unit
      %
      Source records
      2

      Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.

      Show all 2 source records
      1. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:7fa41601-7fb5-4155-8e50-2ae903f0d2d6 (opens source in a new tab)

        Dronedarone label

        Version not recorded · Effective date not recorded

        Absorption Because of presystemic first pass metabolism the absolute bioavailability of dronedarone without food is low, about 4%.
      2. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:3bd4006a-8bad-4909-ac6d-b6d84390155c (opens source in a new tab)

        Dronedarone label

        Version not recorded · Effective date not recorded

        Absorption Because of presystemic first pass metabolism the absolute bioavailability of dronedarone without food is low, about 4%.
  6. Projected row 486

    Medicine slug
    dronedarone
    Compared field
    halfLife
    Comparison state
    agree
    Reason codes
    • COMPATIBLE_VALUES_OVERLAP
    Documents examined
    2
    Source count
    2
    Agreement rate
    1
    Recorded readings
    1. 13 to 19 hours

      Numeric value
      13
      Unit
      hours
      Source records
      2

      Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.

      Show all 2 source records
      1. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:7fa41601-7fb5-4155-8e50-2ae903f0d2d6 (opens source in a new tab)

        Dronedarone label

        Version not recorded · Effective date not recorded

        Its elimination half-life is 13 to 19 hours.
      2. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:3bd4006a-8bad-4909-ac6d-b6d84390155c (opens source in a new tab)

        Dronedarone label

        Version not recorded · Effective date not recorded

        Its elimination half-life is 13 to 19 hours.
  7. Projected row 487

    Medicine slug
    dronedarone
    Compared field
    proteinBinding
    Comparison state
    agree
    Reason codes
    • COMPATIBLE_VALUES_OVERLAP
    Documents examined
    2
    Source count
    2
    Agreement rate
    1
    Recorded readings
    1. >98%

      Numeric value
      98
      Unit
      %
      Source records
      2

      Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.

      Show all 2 source records
      1. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:7fa41601-7fb5-4155-8e50-2ae903f0d2d6 (opens source in a new tab)

        Dronedarone label

        Version not recorded · Effective date not recorded

        Distribution The in vitro plasma protein binding of dronedarone and its N-debutyl metabolite is >98% and not saturable.
      2. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:3bd4006a-8bad-4909-ac6d-b6d84390155c (opens source in a new tab)

        Dronedarone label

        Version not recorded · Effective date not recorded

        Distribution The in vitro plasma protein binding of dronedarone and its N-debutyl metabolite is >98% and not saturable.
  8. Projected row 488

    Medicine slug
    dronedarone
    Compared field
    volumeOfDistribution
    Comparison state
    agree
    Reason codes
    • COMPATIBLE_VALUES_OVERLAP
    Documents examined
    2
    Source count
    2
    Agreement rate
    1
    Recorded readings
    1. 1400 L

      Numeric value
      1,400
      Unit
      L
      Source records
      2

      Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.

      Show all 2 source records
      1. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:7fa41601-7fb5-4155-8e50-2ae903f0d2d6 (opens source in a new tab)

        Dronedarone label

        Version not recorded · Effective date not recorded

        After intravenous (IV) administration the volume of distribution at steady state is about 1400 L.
      2. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:3bd4006a-8bad-4909-ac6d-b6d84390155c (opens source in a new tab)

        Dronedarone label

        Version not recorded · Effective date not recorded

        After intravenous (IV) administration the volume of distribution at steady state is about 1400 L.
  9. Projected row 489

    Medicine slug
    droxidopa
    Compared field
    halfLife
    Comparison state
    agree
    Reason codes
    • COMPATIBLE_VALUES_OVERLAP
    Documents examined
    14
    Source count
    14
    Agreement rate
    1
    Recorded readings
    1. 2.5 hours

      Numeric value
      2.5
      Unit
      hours
      Source records
      14

      Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.

      Show all 14 source records
      1. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:f6dce609-c7d7-48a3-83bb-32ecf00f973f (opens source in a new tab)

        Droxidopa label

        Version not recorded · Effective date not recorded

        Excretion The mean elimination half-life of droxidopa is approximately 2.5 hours in humans.
      2. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:ff263c9a-3db2-45ac-9ba6-8fca47199604 (opens source in a new tab)

        Droxidopa label

        Version not recorded · Effective date not recorded

        Excretion The mean elimination half-life of droxidopa is approximately 2.5 hours in humans.
      3. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:381ffe44-d5d8-4380-a3cd-6d6a5e9ef55d (opens source in a new tab)

        Droxidopa label

        Version not recorded · Effective date not recorded

        Excretion The mean elimination half-life of droxidopa is approximately 2.5 hours in humans.
      4. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:10b02d98-ebb8-4152-bd56-3402417fbf79 (opens source in a new tab)

        Droxidopa label

        Version not recorded · Effective date not recorded

        Excretion The mean elimination half-life of droxidopa is approximately 2.5 hours in humans.
      5. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:6091958e-f04e-47c0-9eef-9c204df4edd9 (opens source in a new tab)

        Droxidopa label

        Version not recorded · Effective date not recorded

        Excretion The mean elimination half-life of droxidopa is approximately 2.5 hours in humans.
      6. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:51ef3096-4622-4f45-a180-ab0dc6d46df9 (opens source in a new tab)

        Droxidopa label

        Version not recorded · Effective date not recorded

        Excretion The mean elimination half-life of droxidopa is approximately 2.5 hours in humans.
      7. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:049f997b-1649-467e-bbb9-bdb991b0bc6e (opens source in a new tab)

        Droxidopa label

        Version not recorded · Effective date not recorded

        Excretion The mean elimination half-life of droxidopa is approximately 2.5 hours in humans.
      8. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:c21ea27c-6e3b-4296-a118-c0b878cdf8f8 (opens source in a new tab)

        Droxidopa label

        Version not recorded · Effective date not recorded

        Excretion The mean elimination half-life of droxidopa is approximately 2.5 hours in humans.
      9. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:04b1f69d-ebba-43b9-8ecd-4f6be7c8a0a0 (opens source in a new tab)

        Droxidopa label

        Version not recorded · Effective date not recorded

        Excretion The mean elimination half-life of droxidopa is approximately 2.5 hours in humans.
      10. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:c3cfd280-3548-b590-e053-2a95a90a5eb3 (opens source in a new tab)

        Droxidopa label

        Version not recorded · Effective date not recorded

        Excretion The mean elimination half-life of droxidopa is approximately 2.5 hours in humans.
      11. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:aa3ce55a-1ea9-4b50-b682-6f25398bcc29 (opens source in a new tab)

        Droxidopa label

        Version not recorded · Effective date not recorded

        Excretion The mean elimination half-life of droxidopa is approximately 2.5 hours in humans.
      12. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:fe08aebb-b390-d176-e053-6394a90a6be7 (opens source in a new tab)

        Droxidopa label

        Version not recorded · Effective date not recorded

        Excretion The mean elimination half-life of droxidopa is approximately 2.5 hours in humans.
      13. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:81b798dc-b8dc-48a5-af46-82bb55f789a8 (opens source in a new tab)

        Droxidopa label

        Version not recorded · Effective date not recorded

        Excretion The mean elimination half-life of droxidopa is approximately 2.5 hours in humans.
      14. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:2179f02c-48d7-48eb-8007-5ae43d8d16bc (opens source in a new tab)

        Droxidopa label

        Version not recorded · Effective date not recorded

        Excretion The mean elimination half-life of droxidopa is approximately 2.5 hours in humans.
  10. Projected row 490

    Medicine slug
    droxidopa
    Compared field
    proteinBinding
    Comparison state
    agree
    Reason codes
    • COMPATIBLE_VALUES_OVERLAP
    Documents examined
    14
    Source count
    14
    Agreement rate
    1
    Recorded readings
    1. 75%

      Numeric value
      75
      Unit
      %
      Source records
      14

      Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.

      Show all 14 source records
      1. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:f6dce609-c7d7-48a3-83bb-32ecf00f973f (opens source in a new tab)

        Droxidopa label

        Version not recorded · Effective date not recorded

        Droxidopa exhibits plasma protein binding of 75% at 100 ng/mL and 26% at 10,000 ng/mL.
      2. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:ff263c9a-3db2-45ac-9ba6-8fca47199604 (opens source in a new tab)

        Droxidopa label

        Version not recorded · Effective date not recorded

        Droxidopa exhibits plasma protein binding of 75% at 100 ng/mL and 26% at 10,000 ng/mL.
      3. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:381ffe44-d5d8-4380-a3cd-6d6a5e9ef55d (opens source in a new tab)

        Droxidopa label

        Version not recorded · Effective date not recorded

        Droxidopa exhibits plasma protein binding of 75% at 100 ng/mL and 26% at 10,000 ng/mL.
      4. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:10b02d98-ebb8-4152-bd56-3402417fbf79 (opens source in a new tab)

        Droxidopa label

        Version not recorded · Effective date not recorded

        Droxidopa exhibits plasma protein binding of 75% at 100 ng/mL and 26% at 10,000 ng/mL.
      5. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:6091958e-f04e-47c0-9eef-9c204df4edd9 (opens source in a new tab)

        Droxidopa label

        Version not recorded · Effective date not recorded

        Droxidopa exhibits plasma protein binding of 75% at 100 ng/mL and 26% at 10,000 ng/mL.
      6. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:51ef3096-4622-4f45-a180-ab0dc6d46df9 (opens source in a new tab)

        Droxidopa label

        Version not recorded · Effective date not recorded

        Droxidopa exhibits plasma protein binding of 75% at 100 ng/mL and 26% at 10,000 ng/mL.
      7. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:049f997b-1649-467e-bbb9-bdb991b0bc6e (opens source in a new tab)

        Droxidopa label

        Version not recorded · Effective date not recorded

        Droxidopa exhibits plasma protein binding of 75% at 100 ng/mL and 26% at 10,000 ng/mL.
      8. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:c21ea27c-6e3b-4296-a118-c0b878cdf8f8 (opens source in a new tab)

        Droxidopa label

        Version not recorded · Effective date not recorded

        Droxidopa exhibits plasma protein binding of 75% at 100 ng/mL and 26% at 10,000 ng/mL.
      9. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:04b1f69d-ebba-43b9-8ecd-4f6be7c8a0a0 (opens source in a new tab)

        Droxidopa label

        Version not recorded · Effective date not recorded

        Droxidopa exhibits plasma protein binding of 75% at 100 ng/mL and 26% at 10,000 ng/mL.
      10. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:c3cfd280-3548-b590-e053-2a95a90a5eb3 (opens source in a new tab)

        Droxidopa label

        Version not recorded · Effective date not recorded

        Droxidopa exhibits plasma protein binding of 75% at 100 ng/mL and 26% at 10,000 ng/mL.
      11. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:aa3ce55a-1ea9-4b50-b682-6f25398bcc29 (opens source in a new tab)

        Droxidopa label

        Version not recorded · Effective date not recorded

        Droxidopa exhibits plasma protein binding of 75% at 100 ng/mL and 26% at 10,000 ng/mL.
      12. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:fe08aebb-b390-d176-e053-6394a90a6be7 (opens source in a new tab)

        Droxidopa label

        Version not recorded · Effective date not recorded

        Droxidopa exhibits plasma protein binding of 75% at 100 ng/mL and 26% at 10,000 ng/mL.
      13. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:81b798dc-b8dc-48a5-af46-82bb55f789a8 (opens source in a new tab)

        Droxidopa label

        Version not recorded · Effective date not recorded

        Droxidopa exhibits plasma protein binding of 75% at 100 ng/mL and 26% at 10,000 ng/mL.
      14. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:2179f02c-48d7-48eb-8007-5ae43d8d16bc (opens source in a new tab)

        Droxidopa label

        Version not recorded · Effective date not recorded

        Droxidopa exhibits plasma protein binding of 75% at 100 ng/mL and 26% at 10,000 ng/mL.

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