Public dataset
Recorded source agreement and disagreement
Show whether sources print one normalized reading, have incompatible units, lack structured comparison context, or contain a context-matched numeric difference.
- Public rows
- 1,681
- Generated
- Schema version
- source-consensus/2
Coverage
What this run contains
- Compared medicine fields
- 1,681
- Agree
- 1,282
- Differ
- 0
- Not comparable
- 12
- Insufficient context
- 387
- Fields represented
- 5
- bioavailability, halfLife, proteinBinding, tMax, volumeOfDistribution
Method
How the rows were made
- Deterministic rules normalize recorded pharmacokinetic readings and compare only like-for-like values.
- One normalized printed reading may be agree even when clinical context was not extracted; this reports printed-reading agreement only.
- Distinct readings may differ only when their units and denominators are comparable and one matching, non-placeholder population/formulation context was structurally extracted. Otherwise they are insufficient_context.
- not_comparable preserves incompatible units or denominators instead of guessing. insufficient_context preserves missing or non-matching structured context instead of manufacturing agreement or disagreement.
- The agreement rate describes the distribution of recorded source readings; it is not a probability that a value is true.
- Every distinct printed reading retains its unit, population context, source count, and complete source records. The API paginates field rows, never child readings or sources.
- documentsExamined is every matching single-substance archive document inspected for that medicine. The generator has no document, reading, or source ceiling, so there is no hidden available-versus-retained remainder.
Limits
Read these before using a row
- Current label parsing does not structurally extract population or formulation context. Distinct otherwise-comparable readings are therefore insufficient_context, never differ; agree may mean printed-reading agreement only. Source records are complete but are not independent-experiment counts.
- The current deterministic parser does not structurally extract population or formulation context from these sentences. It records that context as unknown and cannot publish distinct same-unit readings as differ.
- Neither reading is marked wrong. Population, formulation, route, and other unextracted context may explain the printed difference.
- Only the recorded fields and source documents in this snapshot are compared.
- A source count is the number of retained source records in the row, not a count of independent experiments.
Provenance
Source examples
abacavir · bioavailability · agree
15 documents examined; 83% (Unknown: population and formulation context were not structurally extracted from this source sentence.)
FDA_LABEL:5676d391-f9a4-44be-9604-954b3d8d0e2b (opens source in a new tab)The geometric mean absolute bioavailability of the tablet was 83%.
alemtuzumab · volumeOfDistribution · not_comparable
2 documents examined; 0.18 L/kg (Unknown: population and formulation context were not structurally extracted from this source sentence.); 14.1 L (Unknown: population and formulation context were not structurally extracted from this source sentence.)
FDA_LABEL:4f5f7255-7abc-4328-bd1a-ceaf139ef3e0 (opens source in a new tab)Distribution After the last 30 mg dose, the mean volume of distribution at steady-state was 0.18 L/kg (range 0.1 to 0.4 L/kg).
abiraterone · halfLife · insufficient_context
31 documents examined; 12 ± 5 hours (Unknown: population and formulation context were not structurally extracted from this source sentence.); 18 hours (Unknown: population and formulation context were not structurally extracted from this source sentence.)
FDA_LABEL:c9eb9b46-f847-40a8-802c-a51b40406d5a (opens source in a new tab)Elimination In patients with metastatic CRPC, the mean terminal half-life of abiraterone in plasma (mean ± SD) is 12 ± 5 hours.
Artifact used for this view: data/source-consensus.ndjson. The reader resolves the current run first and uses the checked-in compatibility run only when a current artifact is absent.
Schema
Fields in the public projection
| Field | Type | Meaning |
|---|---|---|
| medicineSlug | string | Stable RNAWiki medicine route key. |
| field | string | Recorded pharmacokinetic field being compared. |
| comparisonState | string | agree (printed-reading agreement), differ (context-matched comparable disjoint values), not_comparable (unit/denominator mismatch), or insufficient_context. Every state remains declared even when its current count is zero. |
| comparisonReasons | string[] | Deterministic codes explaining the state. |
| documentsExamined | number | Recorded source documents considered for the field. |
| sourceCount | number | Recorded source readings represented. |
| agreementRate | number | Share represented by the leading normalized printed-reading group; not a confidence score or clinical agreement probability. |
| readings | consensus-reading[] | Complete, untruncated reading groups. Each keeps the printed display, numeric value when parsed, unit, population context, source count, and every source identity, version/effective date or explicit absence, retrieval date, locator, safe link, and excerpt. |
Reader
Search and filter the rows
Showing 391–400 of 1,681 matching rows. Filters and search terms remain attached when you move between pages or open the API view.
Projected row 391
- Medicine slug
- denosumab-bmwo
- Compared field
- halfLife
- Comparison state
- insufficient_context
- Reason codes
- STRUCTURED_CONTEXT_MISSING
- Documents examined
- 4
- Source count
- 4
- Agreement rate
- 0.5
- Recorded readings
25.4 days
- Numeric value
- Not parsed
- Unit
- Not recorded
- Source records
- 2
Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.
Show all 2 source records
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:10b9eea3-bf70-4ff3-a0b9-54248cbfd156 (opens source in a new tab)
Denosumab-Bmwo label
Version not recorded · Effective date not recorded
Elimination Serum denosumab concentrations declined over a period of 4 to 5 months with a mean half-life of 25.4 days (SD = 8.5 days; n = 46).
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:7a449553-105c-46a1-bb72-849d8f5b81bd (opens source in a new tab)
Denosumab-Bmwo label
Version not recorded · Effective date not recorded
Elimination Serum denosumab concentrations declined over a period of 4 to 5 months with a mean half-life of 25.4 days (SD = 8.5 days; n = 46).
28 days
- Numeric value
- Not parsed
- Unit
- Not recorded
- Source records
- 2
Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.
Show all 2 source records
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:c5a5d750-80be-49cd-b4a6-c8a815956059 (opens source in a new tab)
Denosumab-Bmwo label
Version not recorded · Effective date not recorded
The mean elimination half-life was 28 days.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:d378622d-3a13-4918-ae18-3375cd10d270 (opens source in a new tab)
Denosumab-Bmwo label
Version not recorded · Effective date not recorded
The mean elimination half-life was 28 days.
Projected row 392
- Medicine slug
- denosumab-bmwo
- Compared field
- volumeOfDistribution
- Comparison state
- agree
- Reason codes
- COMPATIBLE_VALUES_OVERLAP
- Documents examined
- 4
- Source count
- 2
- Agreement rate
- 1
- Recorded readings
5.2 L
- Numeric value
- 5.2
- Unit
- L
- Source records
- 2
Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.
Show all 2 source records
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:10b9eea3-bf70-4ff3-a0b9-54248cbfd156 (opens source in a new tab)
Denosumab-Bmwo label
Version not recorded · Effective date not recorded
Distribution The mean volume of distribution for denosumab was 5.2 L (SD = 1.7 L).
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:7a449553-105c-46a1-bb72-849d8f5b81bd (opens source in a new tab)
Denosumab-Bmwo label
Version not recorded · Effective date not recorded
Distribution The mean volume of distribution for denosumab was 5.2 L (SD = 1.7 L).
Projected row 393
- Medicine slug
- denosumab-desu
- Compared field
- halfLife
- Comparison state
- insufficient_context
- Reason codes
- STRUCTURED_CONTEXT_MISSING
- Documents examined
- 2
- Source count
- 2
- Agreement rate
- 0.5
- Recorded readings
25.4 days
- Numeric value
- Not parsed
- Unit
- Not recorded
- Source records
- 1
Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.
Show all 1 source records
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:5f3be096-5100-4d0e-b765-481bbb2672e1 (opens source in a new tab)
Denosumab-Desu label
Version not recorded · Effective date not recorded
Elimination Serum denosumab concentrations declined over a period of 4 to 5 months with a mean half-life of 25.4 days (SD=8.5 days; n=46) A population pharmacokinetic analysis was performed to evaluate the effects of demographic characteristics.
28 days
- Numeric value
- Not parsed
- Unit
- Not recorded
- Source records
- 1
Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.
Show all 1 source records
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:e15dfe74-1575-4a2a-895e-323c05613362 (opens source in a new tab)
Denosumab-Desu label
Version not recorded · Effective date not recorded
The mean elimination half-life was 28 days.
Projected row 394
- Medicine slug
- denosumab-kyqq
- Compared field
- halfLife
- Comparison state
- insufficient_context
- Reason codes
- STRUCTURED_CONTEXT_MISSING
- Documents examined
- 2
- Source count
- 2
- Agreement rate
- 0.5
- Recorded readings
25.4 days
- Numeric value
- Not parsed
- Unit
- Not recorded
- Source records
- 1
Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.
Show all 1 source records
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:1e5e8c88-3c65-3076-e44b-02d92c2d343d (opens source in a new tab)
Denosumab-Kyqq label
Version not recorded · Effective date not recorded
Elimination Serum denosumab concentrations declined over a period of 4 to 5 months with a mean half-life of 25.4 days (SD = 8.5 days; n = 46).
28 days
- Numeric value
- Not parsed
- Unit
- Not recorded
- Source records
- 1
Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.
Show all 1 source records
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:547cb095-f7f5-f933-75ce-5e6abf2ad5bc (opens source in a new tab)
Denosumab-Kyqq label
Version not recorded · Effective date not recorded
The mean elimination half-life was 28 days.
Projected row 395
- Medicine slug
- denosumab-mobz
- Compared field
- halfLife
- Comparison state
- insufficient_context
- Reason codes
- STRUCTURED_CONTEXT_MISSING
- Documents examined
- 2
- Source count
- 2
- Agreement rate
- 0.5
- Recorded readings
25.4 days
- Numeric value
- Not parsed
- Unit
- Not recorded
- Source records
- 1
Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.
Show all 1 source records
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:29140df2-24a3-4a6f-a8e3-065521448d61 (opens source in a new tab)
Denosumab-Mobz label
Version not recorded · Effective date not recorded
Elimination Serum denosumab concentrations declined over a period of 4 to 5 months with a mean half-life of 25.4 days (SD = 8.5 days; n = 46).
28 days
- Numeric value
- Not parsed
- Unit
- Not recorded
- Source records
- 1
Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.
Show all 1 source records
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:f040a245-1be4-4962-a8b7-a13ee7fac707 (opens source in a new tab)
Denosumab-Mobz label
Version not recorded · Effective date not recorded
The mean elimination half-life was 28 days.
Projected row 396
- Medicine slug
- denosumab-qbde
- Compared field
- halfLife
- Comparison state
- insufficient_context
- Reason codes
- STRUCTURED_CONTEXT_MISSING
- Documents examined
- 2
- Source count
- 2
- Agreement rate
- 0.5
- Recorded readings
25.4 days
- Numeric value
- Not parsed
- Unit
- Not recorded
- Source records
- 1
Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.
Show all 1 source records
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:815d3ba4-27a1-4a06-925a-a87f35442bdb (opens source in a new tab)
Denosumab-Qbde label
Version not recorded · Effective date not recorded
Elimination Serum denosumab concentrations declined over a period of 4 to 5 months with a mean half-life of 25.4 days (SD = 8.5 days; n = 46).
28 days
- Numeric value
- Not parsed
- Unit
- Not recorded
- Source records
- 1
Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.
Show all 1 source records
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:a48a3a33-6b0e-4cf4-8786-8f662d6ee77b (opens source in a new tab)
Denosumab-Qbde label
Version not recorded · Effective date not recorded
The mean elimination half-life was 28 days.
Projected row 397
- Medicine slug
- desloratadine
- Compared field
- halfLife
- Comparison state
- agree
- Reason codes
- COMPATIBLE_VALUES_OVERLAP
- Documents examined
- 13
- Source count
- 13
- Agreement rate
- 1
- Recorded readings
50 hours
- Numeric value
- 50
- Unit
- hours
- Source records
- 13
Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.
Show all 13 source records
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:4d094001-b85a-47b3-bc67-a46660384ece (opens source in a new tab)
Desloratadine label
Version not recorded · Effective date not recorded
In pharmacokinetic studies (n=3748), approximately 6% of subjects were poor metabolizers of desloratadine (defined as a subject with an AUC ratio of 3-hydroxydesloratadine to desloratadine less than 0.1, or a subject with a desloratadine half-life exceeding 50 hours).
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:cf7f838b-4595-4c81-97b9-e1594347e1bd (opens source in a new tab)
Desloratadine label
Version not recorded · Effective date not recorded
In pharmacokinetic studies (n=3748), approximately 6% of subjects were poor metabolizers of desloratadine (defined as a subject with an AUC ratio of 3-hydroxydesloratadine to desloratadine less than 0.1, or a subject with a desloratadine half-life exceeding 50 hours).
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:e5d1f465-e436-b4fd-d351-07a7b2acb440 (opens source in a new tab)
Desloratadine label
Version not recorded · Effective date not recorded
In pharmacokinetic studies (n=3748), approximately 6% of subjects were poor metabolizers of desloratadine (defined as a subject with an AUC ratio of 3-hydroxydesloratadine to desloratadine less than 0.1, or a subject with a desloratadine half-life exceeding 50 hours).
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:f84c8de3-a7d3-4e8b-bfb6-04259e79450a (opens source in a new tab)
Desloratadine label
Version not recorded · Effective date not recorded
In pharmacokinetic studies (n=3748), approximately 6% of subjects were poor metabolizers of desloratadine (defined as a subject with an AUC ratio of 3-hydroxydesloratadine to desloratadine less than 0.1, or a subject with a desloratadine half-life exceeding 50 hours).
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:e4db30a5-48e5-4fe3-8793-30b6866f87c1 (opens source in a new tab)
Desloratadine label
Version not recorded · Effective date not recorded
In pharmacokinetic studies (n = 3748), approximately 6% of subjects were poor metabolizers of desloratadine (defined as a subject with an AUC ratio of 3-hydroxydesloratadine to desloratadine less than 0.1, or a subject with a desloratadine half-life exceeding 50 hours).
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:0fe374d0-c14b-4102-b568-eb79165fc7ef (opens source in a new tab)
Desloratadine label
Version not recorded · Effective date not recorded
In pharmacokinetic studies (n=3748), approximately 6% of subjects were poor metabolizers of desloratadine (defined as a subject with an AUC ratio of 3-hydroxydesloratadine to desloratadine less than 0.1, or a subject with a desloratadine half-life exceeding 50 hours).
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:41d5e0d4-6188-847b-e063-6294a90a2e2f (opens source in a new tab)
Desloratadine label
Version not recorded · Effective date not recorded
In pharmacokinetic studies (n=3,748), approximately 6% of subjects were poor metabolizers of desloratadine (defined as a subject with an AUC ratio of 3-hydroxydesloratadine to desloratadine less than 0.1, or a subject with a desloratadine half-life exceeding 50 hours).
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:36307c2b-6b6a-46a9-9fe4-1798fc72e7b8 (opens source in a new tab)
Desloratadine label
Version not recorded · Effective date not recorded
In pharmacokinetic studies (n=3748), approximately 6% of subjects were poor metabolizers of desloratadine (defined as a subject with an AUC ratio of 3-hydroxydesloratadine to desloratadine less than 0.1, or a subject with a desloratadine half-life exceeding 50 hours).
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:21174c0f-9204-4c75-b6e6-2f9ada5b535d (opens source in a new tab)
Desloratadine label
Version not recorded · Effective date not recorded
In pharmacokinetic studies (n=3748), approximately 6% of subjects were poor metabolizers of desloratadine (defined as a subject with an AUC ratio of 3-hydroxydesloratadine to desloratadine less than 0.1, or a subject with a desloratadine half-life exceeding 50 hours).
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:a3b61ab9-ec20-4831-b69a-fcd913fce540 (opens source in a new tab)
Desloratadine label
Version not recorded · Effective date not recorded
In pharmacokinetic studies (n=3748), approximately 6% of subjects were poor metabolizers of desloratadine (defined as a subject with an AUC ratio of 3-hydroxydesloratadine to desloratadine less than 0.1, or a subject with a desloratadine half-life exceeding 50 hours).
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:2a90b899-7746-43dc-ac8a-e754428eb30c (opens source in a new tab)
Desloratadine label
Version not recorded · Effective date not recorded
In pharmacokinetic studies (n=3748), approximately 6% of subjects were poor metabolizers of desloratadine (defined as a subject with an AUC ratio of 3-hydroxydesloratadine to desloratadine less than 0.1, or a subject with a desloratadine half-life exceeding 50 hours).
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:69b9635b-c790-4316-a790-67b0f5512b72 (opens source in a new tab)
Desloratadine label
Version not recorded · Effective date not recorded
In pharmacokinetic studies (n=3748), approximately 6% of subjects were poor metabolizers of desloratadine (defined as a subject with an AUC ratio of 3-hydroxydesloratadine to desloratadine less than 0.1, or a subject with a desloratadine half-life exceeding 50 hours).
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:c671342e-69a2-4ca5-abc2-8166ed4240d4 (opens source in a new tab)
Desloratadine label
Version not recorded · Effective date not recorded
In pharmacokinetic studies (n=3748), approximately 6% of subjects were poor metabolizers of desloratadine (defined as a subject with an AUC ratio of 3-hydroxydesloratadine to desloratadine less than 0.1, or a subject with a desloratadine half-life exceeding 50 hours).
Projected row 398
- Medicine slug
- desloratadine
- Compared field
- tMax
- Comparison state
- agree
- Reason codes
- COMPATIBLE_VALUES_OVERLAP
- Documents examined
- 13
- Source count
- 12
- Agreement rate
- 1
- Recorded readings
3 hours
- Numeric value
- 3
- Unit
- hours
- Source records
- 12
Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.
Show all 12 source records
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:4d094001-b85a-47b3-bc67-a46660384ece (opens source in a new tab)
Desloratadine label
Version not recorded · Effective date not recorded
etics Absorption Following oral administration of a desloratadine 5 mg tablet once daily for 10 days to normal healthy volunteers, the mean time to maximum plasma concentrations (T max ) occurred at approximately 3 hours post dose and mean steady state peak plasma concentrations (C max ) and AUC of 4 ng/mL and 56.9 ng·hr/mL were observed, respectively.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:cf7f838b-4595-4c81-97b9-e1594347e1bd (opens source in a new tab)
Desloratadine label
Version not recorded · Effective date not recorded
12.3 Pharmacokinetics Absorption Following oral administration of a desloratadine 5 mg tablet once daily for 10 days to normal healthy volunteers, the mean time to maximum plasma concentrations (T max ) occurred at approximately 3 hours post dose and mean steady state peak plasma concentrations (C max ) and AUC of 4 ng/mL and 56.9 ng∙hr/mL were observed, respectively.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:f84c8de3-a7d3-4e8b-bfb6-04259e79450a (opens source in a new tab)
Desloratadine label
Version not recorded · Effective date not recorded
12.3 Pharmacokinetics Absorption Following oral administration of a desloratadine 5 mg tablet once daily for 10 days to normal healthy volunteers, the mean time to maximum plasma concentrations (T max ) occurred at approximately 3 hours post dose and mean steady state peak plasma concentrations (C max ) and AUC of 4 ng/mL and 56.9 ng∙hr/mL were observed, respectively.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:e4db30a5-48e5-4fe3-8793-30b6866f87c1 (opens source in a new tab)
Desloratadine label
Version not recorded · Effective date not recorded
12.3 Pharmacokinetics Absorption Following oral administration of a desloratadine 5 mg tablet once daily for 10 days to normal healthy volunteers, the mean time to maximum plasma concentrations (T max ) occurred at approximately 3 hours post dose and mean steady state peak plasma concentrations (C max ) and AUC of 4 ng/mL and 56.9 ng•hr/mL were observed, respectively.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:0fe374d0-c14b-4102-b568-eb79165fc7ef (opens source in a new tab)
Desloratadine label
Version not recorded · Effective date not recorded
12.3 Pharmacokinetics Absorption Following oral administration of a desloratadine 5 mg tablet once daily for 10 days to normal healthy volunteers, the mean time to maximum plasma concentrations (T max ) occurred at approximately 3 hours post dose and mean steady state peak plasma concentrations (C max ) and AUC of 4 ng/mL and 56.9 ng∙hr/mL were observed, respectively.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:41d5e0d4-6188-847b-e063-6294a90a2e2f (opens source in a new tab)
Desloratadine label
Version not recorded · Effective date not recorded
etics Absorption: Following oral administration of a desloratadine 5 mg tablet once daily for 10 days to normal healthy volunteers, the mean time to maximum plasma concentrations (Tmax) occurred at approximately 3 hours post dose and mean steady state peak plasma concentrations (Cmax) and AUC of 4 ng/mL and 56.9 ng∙hr/mL were observed, respectively.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:36307c2b-6b6a-46a9-9fe4-1798fc72e7b8 (opens source in a new tab)
Desloratadine label
Version not recorded · Effective date not recorded
12.3 Pharmacokinetics Absorption Following oral administration of a desloratadine 5 mg tablet once daily for 10 days to normal healthy volunteers, the mean time to maximum plasma concentrations (T max ) occurred at approximately 3 hours post dose and mean steady state peak plasma concentrations (C max ) and AUC of 4 ng/mL and 56.9 ng∙hr/mL were observed, respectively.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:21174c0f-9204-4c75-b6e6-2f9ada5b535d (opens source in a new tab)
Desloratadine label
Version not recorded · Effective date not recorded
etics Absorption Following oral administration of a desloratadine 5 mg tablet once daily for 10 days to normal healthy volunteers, the mean time to maximum plasma concentrations (T max ) occurred at approximately 3 hours post dose and mean steady state peak plasma concentrations (C max ) and AUC of 4 ng/mL and 56.9 ng-hr/mL were observed, respectively.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:a3b61ab9-ec20-4831-b69a-fcd913fce540 (opens source in a new tab)
Desloratadine label
Version not recorded · Effective date not recorded
12.3 Pharmacokinetics Absorption Following oral administration of a desloratadine 5 mg tablet once daily for 10 days to normal healthy volunteers, the mean time to maximum plasma concentrations (T max ) occurred at approximately 3 hours post dose and mean steady state peak plasma concentrations (C max ) and AUC of 4 ng/mL and 56.9 ng∙hr/mL were observed, respectively.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:2a90b899-7746-43dc-ac8a-e754428eb30c (opens source in a new tab)
Desloratadine label
Version not recorded · Effective date not recorded
12.3 Pharmacokinetics Absorption Following oral administration of a desloratadine 5 mg tablet once daily for 10 days to normal healthy volunteers, the mean time to maximum plasma concentrations (T max ) occurred at approximately 3 hours post dose and mean steady state peak plasma concentrations (C max ) and AUC of 4 ng/mL and 56.9 ng∙hr/mL were observed, respectively.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:69b9635b-c790-4316-a790-67b0f5512b72 (opens source in a new tab)
Desloratadine label
Version not recorded · Effective date not recorded
12.3 Pharmacokinetics Absorption Following oral administration of a desloratadine 5 mg tablet once daily for 10 days to normal healthy volunteers, the mean time to maximum plasma concentrations (T max ) occurred at approximately 3 hours post dose and mean steady state peak plasma concentrations (C max ) and AUC of 4 ng/mL and 56.9 ng∙hr/mL were observed, respectively.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:c671342e-69a2-4ca5-abc2-8166ed4240d4 (opens source in a new tab)
Desloratadine label
Version not recorded · Effective date not recorded
12.3 Pharmacokinetics Absorption Following oral administration of a desloratadine 5-mg tablet once daily for 10 days to normal healthy volunteers, the mean time to maximum plasma concentrations (T max ) occurred at approximately 3 hours post dose and mean steady state peak plasma concentrations (C max ) and AUC of 4 ng/mL and 56.9 ng∙hr/mL were observed, respectively.
Projected row 399
- Medicine slug
- desmopressin
- Compared field
- bioavailability
- Comparison state
- insufficient_context
- Reason codes
- STRUCTURED_CONTEXT_MISSING
- Documents examined
- 43
- Source count
- 14
- Agreement rate
- 0.928571
- Recorded readings
5%
- Numeric value
- 5
- Unit
- %
- Source records
- 13
Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.
Show all 13 source records
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:7a26b415-77cd-4b2f-9c76-fa52d2eb6be6 (opens source in a new tab)
Desmopressin label
Version not recorded · Effective date not recorded
The bioavailability of desmopressin acetate oral tablets is about 5% compared to intranasal desmopressin acetate, and about 0.16% compared to intravenous desmopressin acetate.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:dc9b0dad-d265-4dff-8191-d936280d85a2 (opens source in a new tab)
Desmopressin label
Version not recorded · Effective date not recorded
The bioavailability of desmopressin acetate oral tablets is about 5% compared to intranasal desmopressin acetate, and about 0.16% compared to intravenous desmopressin acetate.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:52133714-37d1-458d-9839-f0bd206711ea (opens source in a new tab)
Desmopressin label
Version not recorded · Effective date not recorded
The bioavailability of Desmopressin Acetate oral tablets is about 5% compared to intranasal desmopressin acetate, and about 0.16% compared to intravenous desmopressin acetate.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:9fba5e90-f541-4588-a5e9-b56198f17e87 (opens source in a new tab)
Desmopressin label
Version not recorded · Effective date not recorded
The bioavailability of desmopressin acetate oral tablets is about 5% compared to intranasal desmopressin acetate, and about 0.16% compared to intravenous desmopressin acetate.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:72aeef35-c102-b628-0219-9822651887eb (opens source in a new tab)
Desmopressin label
Version not recorded · Effective date not recorded
The bioavailability of desmopressin acetate oral tablets is about 5% compared to intranasal desmopressin acetate, and about 0.16% compared to intravenous desmopressin acetate.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:0d447b48-3f4b-430e-9e68-d8b9401c002e (opens source in a new tab)
Desmopressin label
Version not recorded · Effective date not recorded
The bioavailability of desmopressin acetate oral tablets is about 5% compared to intranasal desmopressin acetate, and about 0.16% compared to intravenous desmopressin acetate.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:6d55baa9-2b62-469c-93ae-3909ab249332 (opens source in a new tab)
Desmopressin label
Version not recorded · Effective date not recorded
The bioavailability of DDAVP oral tablets is about 5% compared to intranasal DDAVP, and about 0.16% compared to intravenous DDAVP.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:24866ad0-94db-46a2-96c0-b362acd0271a (opens source in a new tab)
Desmopressin label
Version not recorded · Effective date not recorded
The bioavailability of desmopressin acetate oral tablets are about 5% compared to intranasal desmopressin acetate, and about 0.16% compared to intravenous desmopressin acetate.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:f140926e-3201-4b8e-8207-14c560ddb55e (opens source in a new tab)
Desmopressin label
Version not recorded · Effective date not recorded
The bioavailability of desmopressin acetate oral tablets are about 5% compared to intranasal desmopressin acetate, and about 0.16% compared to intravenous desmopressin acetate.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:f306e2d4-781f-ff8f-e053-2a95a90ad15b (opens source in a new tab)
Desmopressin label
Version not recorded · Effective date not recorded
The bioavailability of desmopressin acetate oral tablets is about 5% compared to intranasal desmopressin acetate, and about 0.16% compared to intravenous desmopressin acetate.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:e87b6cfd-5677-4398-883d-7ced5dd678ef (opens source in a new tab)
Desmopressin label
Version not recorded · Effective date not recorded
The bioavailability of desmopressin acetate oral tablets is about 5% compared to intranasal desmopressin acetate, and about 0.16% compared to intravenous desmopressin acetate.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:c04357fd-478a-4909-b098-ae6710be071c (opens source in a new tab)
Desmopressin label
Version not recorded · Effective date not recorded
The bioavailability of desmopressin acetate oral tablets is about 5% compared to intranasal desmopressin acetate, and about 0.16% compared to intravenous desmopressin acetate.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:c01048e8-d28f-4085-9c37-3d5d48395a77 (opens source in a new tab)
Desmopressin label
Version not recorded · Effective date not recorded
The bioavailability of Desmopressin Acetate oral tablets is about 5% compared to intranasal desmopressin acetate, and about 0.16% compared to intravenous desmopressin acetate.
0.16%
- Numeric value
- 0.16
- Unit
- %
- Source records
- 1
Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.
Show all 1 source records
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:4c0e1356-d14f-cfb4-e063-6294a90acd27 (opens source in a new tab)
Desmopressin label
Version not recorded · Effective date not recorded
Absorption Desmopressin absolute oral bioavailability is 0.16%.
Projected row 400
- Medicine slug
- desmopressin
- Compared field
- halfLife
- Comparison state
- insufficient_context
- Reason codes
- STRUCTURED_CONTEXT_MISSING
- Documents examined
- 43
- Source count
- 43
- Agreement rate
- 0.55814
- Recorded readings
2.8 hours
- Numeric value
- 2.8
- Unit
- hours
- Source records
- 24
Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.
Show all 24 source records
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:7f4e5a22-85e8-4c28-9ebf-d6ebc75ad653 (opens source in a new tab)
Desmopressin label
Version not recorded · Effective date not recorded
12.3 Pharmacokinetics Elimination The geometric mean terminal half-life is 2.8 hours.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:cdec2cc2-4fd9-474e-884f-d0599e40948f (opens source in a new tab)
Desmopressin label
Version not recorded · Effective date not recorded
12.3 Pharmacokinetics Elimination The geometric mean terminal half-life is 2.8 hours.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:c2e21331-4d54-4fa7-8f0d-31fe23a981aa (opens source in a new tab)
Desmopressin label
Version not recorded · Effective date not recorded
12.3 Pharmacokinetics Elimination The geometric mean terminal half-life is 2.8 hours.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:1ac423b8-27a6-4cef-4a82-c50bf81b4f49 (opens source in a new tab)
Desmopressin label
Version not recorded · Effective date not recorded
The terminal half-life was 2.8 hours in subjects with normal renal function, 4.0 hours in mild renal impairment, 6.6 hours in moderate renal impairment and 8.7 hours in severe renal impairment.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:539d7da2-72b8-45f9-836c-4e3351dd488e (opens source in a new tab)
Desmopressin label
Version not recorded · Effective date not recorded
12.3 Pharmacokinetics Elimination The geometric mean terminal half-life is 2.8 hours.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:60dd8694-58d8-d88e-26f2-f28baa53787e (opens source in a new tab)
Desmopressin label
Version not recorded · Effective date not recorded
12.3 Pharmacokinetics Elimination The geometric mean terminal half-life is 2.8 hours.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:39381e84-0e87-4731-b725-f0fdf4b5ca2b (opens source in a new tab)
Desmopressin label
Version not recorded · Effective date not recorded
12.3 Pharmacokinetics Elimination The geometric mean terminal half-life is 2.8 hours.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:40752c75-d09b-4013-9024-442048145b63 (opens source in a new tab)
Desmopressin label
Version not recorded · Effective date not recorded
12.3 Pharmacokinetics Elimination The geometric mean terminal half-life is 2.8 hours.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:9725ba8e-ac0f-4655-bb98-9ea926142815 (opens source in a new tab)
Desmopressin label
Version not recorded · Effective date not recorded
12.3 Pharmacokinetics Elimination The geometric mean terminal half-life is 2.8 hours.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:1052a869-b64d-655d-e063-6294a90ad0e2 (opens source in a new tab)
Desmopressin label
Version not recorded · Effective date not recorded
12.3 Pharmacokinetics Elimination The geometric mean terminal half-life is 2.8 hours.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:8ca799f1-7029-4527-9ab4-7512504bb8e2 (opens source in a new tab)
Desmopressin label
Version not recorded · Effective date not recorded
The terminal half-life was 2.8 hours in subjects with normal renal function, 4.0 hours in mild renal impairment, 6.6 hours in moderate renal impairment and 8.7 hours in severe renal impairment.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:0d96944d-736d-4b56-b726-d21eacd8bc85 (opens source in a new tab)
Desmopressin label
Version not recorded · Effective date not recorded
12.3 Pharmacokinetics Elimination The geometric mean terminal half-life is 2.8 hours.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:2a2a6eba-c5bf-4ee4-bb18-c992ae59dce5 (opens source in a new tab)
Desmopressin label
Version not recorded · Effective date not recorded
12.3 Pharmacokinetics Elimination The geometric mean terminal half-life is 2.8 hours.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:651f6fee-a2c7-431b-8d5d-58b156c72244 (opens source in a new tab)
Desmopressin label
Version not recorded · Effective date not recorded
12.3 Pharmacokinetics Elimination The geometric mean terminal half-life is 2.8 hours.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:131fd4d8-48ca-4c1f-8165-848dc0a4d511 (opens source in a new tab)
Desmopressin label
Version not recorded · Effective date not recorded
12.3 Pharmacokinetics Elimination The geometric mean terminal half-life is 2.8 hours.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:d87168b9-f103-4ba5-b0b3-0656d1c81da2 (opens source in a new tab)
Desmopressin label
Version not recorded · Effective date not recorded
12.3 Pharmacokinetics Elimination The geometric mean terminal half-life is 2.8 hours.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:f5ada39c-20ed-4500-9dce-1e4ab642a358 (opens source in a new tab)
Desmopressin label
Version not recorded · Effective date not recorded
The geometric mean terminal half-life was 2.8 hours in subjects with normal renal function, and 4, 6.6, and 8.7 hours in subjects with mild, moderate, and severe renal impairment, respectively.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:8034989a-45f5-436b-8b1f-42108ee2a21a (opens source in a new tab)
Desmopressin label
Version not recorded · Effective date not recorded
The terminal half-life was 2.8 hours in subjects with normal renal function, 4.0 hours in mild renal impairment, 6.6 hours in moderate renal impairment and 8.7 hours in severe renal impairment.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:848d5173-ce26-46bf-b180-7ed13f0233b5 (opens source in a new tab)
Desmopressin label
Version not recorded · Effective date not recorded
12.3 Pharmacokinetics Elimination The geometric mean terminal half-life is 2.8 hours.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:10b29aa2-274e-4c29-bccd-424bd3761758 (opens source in a new tab)
Desmopressin label
Version not recorded · Effective date not recorded
12.3 Pharmacokinetics Elimination The geometric mean terminal half-life is 2.8 hours.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:84dbb392-4535-4cbc-af60-75abb494f26e (opens source in a new tab)
Desmopressin label
Version not recorded · Effective date not recorded
12.3 Pharmacokinetics Elimination The geometric mean terminal half-life is 2.8 hours.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:673cd9ab-b714-49ee-9ce7-c99be605c30e (opens source in a new tab)
Desmopressin label
Version not recorded · Effective date not recorded
12.3 Pharmacokinetics Elimination The geometric mean terminal half-life is 2.8 hours.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:9fd48eec-aa24-4888-b99f-d409ada958a7 (opens source in a new tab)
Desmopressin label
Version not recorded · Effective date not recorded
12.3 Pharmacokinetics Elimination The geometric mean terminal half-life is 2.8 hours.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:29df0492-f7ef-47bb-aa67-4ef9e5c2846f (opens source in a new tab)
Desmopressin label
Version not recorded · Effective date not recorded
12.3 Pharmacokinetics Elimination The geometric mean terminal half-life is 2.8 hours.
3 hours
- Numeric value
- 3
- Unit
- hours
- Source records
- 15
Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.
Show all 15 source records
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:7a26b415-77cd-4b2f-9c76-fa52d2eb6be6 (opens source in a new tab)
Desmopressin label
Version not recorded · Effective date not recorded
Terminal half-life significantly increased from 3 hours in normal healthy patients to 9 hours in patients with severe renal impairment.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:dc9b0dad-d265-4dff-8191-d936280d85a2 (opens source in a new tab)
Desmopressin label
Version not recorded · Effective date not recorded
Terminal half-life significantly increased from 3 hours in normal healthy patients to 9 hours in patients with severe renal impairment.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:52133714-37d1-458d-9839-f0bd206711ea (opens source in a new tab)
Desmopressin label
Version not recorded · Effective date not recorded
Terminal half-life significantly increased from 3 hours in normal healthy patients to 9 hours in patients with severe renal impairment.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:15179e0c-f677-307f-d1e1-5910de4c212f (opens source in a new tab)
Desmopressin label
Version not recorded · Effective date not recorded
Terminal half-life significantly increased from 3 hours in normal healthy patients to 9 hours in patients with severe renal impairment.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:9fba5e90-f541-4588-a5e9-b56198f17e87 (opens source in a new tab)
Desmopressin label
Version not recorded · Effective date not recorded
Terminal half-life significantly increased from 3 hours in normal healthy patients to 9 hours in patients with severe renal impairment (See CONTRAINDICATIONS ).
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:72aeef35-c102-b628-0219-9822651887eb (opens source in a new tab)
Desmopressin label
Version not recorded · Effective date not recorded
Terminal half-life significantly increased from 3 hours in normal healthy patients to 9 hours in patients with severe renal impairment.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:0d447b48-3f4b-430e-9e68-d8b9401c002e (opens source in a new tab)
Desmopressin label
Version not recorded · Effective date not recorded
Terminal half-life significantly increased from 3 hours in normal healthy patients to 9 hours in patients with severe renal impairment.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:6d55baa9-2b62-469c-93ae-3909ab249332 (opens source in a new tab)
Desmopressin label
Version not recorded · Effective date not recorded
Terminal half-life significantly increased from 3 hours in normal healthy patients to 9 hours in patients with severe renal impairment.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:2dc2cec8-6953-4a33-9356-11534fba1fb8 (opens source in a new tab)
Desmopressin label
Version not recorded · Effective date not recorded
Terminal half-life significantly increased from 3 hours in normal healthy patients to 9 hours in patients with severe renal impairment.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:24866ad0-94db-46a2-96c0-b362acd0271a (opens source in a new tab)
Desmopressin label
Version not recorded · Effective date not recorded
Terminal half-life significantly increased from 3 hours in normal healthy patients to 9 hours in patients with severe renal impairment.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:f140926e-3201-4b8e-8207-14c560ddb55e (opens source in a new tab)
Desmopressin label
Version not recorded · Effective date not recorded
Terminal half-life significantly increased from 3 hours in normal healthy patients to 9 hours in patients with severe renal impairment.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:f306e2d4-781f-ff8f-e053-2a95a90ad15b (opens source in a new tab)
Desmopressin label
Version not recorded · Effective date not recorded
Terminal half-life significantly increased from 3 hours in normal healthy patients to 9 hours in patients with severe renal impairment (See CONTRAINDICATIONS ).
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:e87b6cfd-5677-4398-883d-7ced5dd678ef (opens source in a new tab)
Desmopressin label
Version not recorded · Effective date not recorded
Terminal half-life significantly increased from 3 hours in normal healthy patients to 9 hours in patients with severe renal impairment (see CONTRAINDICATIONS ).
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:c04357fd-478a-4909-b098-ae6710be071c (opens source in a new tab)
Desmopressin label
Version not recorded · Effective date not recorded
Terminal half-life significantly increased from 3 hours in normal healthy patients to 9 hours in patients with severe renal impairment.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:c01048e8-d28f-4085-9c37-3d5d48395a77 (opens source in a new tab)
Desmopressin label
Version not recorded · Effective date not recorded
Terminal half-life significantly increased from 3 hours in normal healthy patients to 9 hours in patients with severe renal impairment.
8-12 hours
- Numeric value
- 8
- Unit
- hours
- Source records
- 3
Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.
Show all 3 source records
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:b01c22dc-eecd-11b2-e053-2a95a90a529a (opens source in a new tab)
Desmopressin label
Version not recorded · Effective date not recorded
The duration of the hemostatic effect depends on the half-life for VIII:C which is about 8-12 hours.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:52680415-52a0-61c2-e063-6294a90ae27e (opens source in a new tab)
Desmopressin label
Version not recorded · Effective date not recorded
The duration of the hemostatic effect depends on the half-life for VIII:C which is about 8 to 12 hours.
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:b2fad59d-6176-4e09-9fbb-5cdd7f8f1568 (opens source in a new tab)
Desmopressin label
Version not recorded · Effective date not recorded
The duration of the hemostatic effect depends on the half-life for VIII:C which is about 8-12 hours.
3.6 hours
- Numeric value
- 3.6
- Unit
- hours
- Source records
- 1
Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.
Show all 1 source records
- FDA_LABELRetrieved 2026-08-30FDA_LABEL:4c0e1356-d14f-cfb4-e063-6294a90acd27 (opens source in a new tab)
Desmopressin label
Version not recorded · Effective date not recorded
Desmopressin estimated elimination half-life is 3.6 hours.
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- Exact recorded field key.Values: bioavailability, halfLife, proteinBinding, tMax, volumeOfDistribution
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