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Public dataset

Recorded source agreement and disagreement

Show whether sources print one normalized reading, have incompatible units, lack structured comparison context, or contain a context-matched numeric difference.

What this does not mean: agree can mean only that sources print the same normalized reading; it is not clinical-context equivalence, independent replication, or proof. differ requires matching structured context and disjoint comparable values. not_comparable and insufficient_context are not disagreement.
Public rows
1,681
Generated
Schema version
source-consensus/2

Coverage

What this run contains

Compared medicine fields
1,681
Agree
1,282
Differ
0
Not comparable
12
Insufficient context
387
Fields represented
5
bioavailability, halfLife, proteinBinding, tMax, volumeOfDistribution

Method

How the rows were made

  1. Deterministic rules normalize recorded pharmacokinetic readings and compare only like-for-like values.
  2. One normalized printed reading may be agree even when clinical context was not extracted; this reports printed-reading agreement only.
  3. Distinct readings may differ only when their units and denominators are comparable and one matching, non-placeholder population/formulation context was structurally extracted. Otherwise they are insufficient_context.
  4. not_comparable preserves incompatible units or denominators instead of guessing. insufficient_context preserves missing or non-matching structured context instead of manufacturing agreement or disagreement.
  5. The agreement rate describes the distribution of recorded source readings; it is not a probability that a value is true.
  6. Every distinct printed reading retains its unit, population context, source count, and complete source records. The API paginates field rows, never child readings or sources.
  7. documentsExamined is every matching single-substance archive document inspected for that medicine. The generator has no document, reading, or source ceiling, so there is no hidden available-versus-retained remainder.

Limits

Read these before using a row

  • Current label parsing does not structurally extract population or formulation context. Distinct otherwise-comparable readings are therefore insufficient_context, never differ; agree may mean printed-reading agreement only. Source records are complete but are not independent-experiment counts.
  • The current deterministic parser does not structurally extract population or formulation context from these sentences. It records that context as unknown and cannot publish distinct same-unit readings as differ.
  • Neither reading is marked wrong. Population, formulation, route, and other unextracted context may explain the printed difference.
  • Only the recorded fields and source documents in this snapshot are compared.
  • A source count is the number of retained source records in the row, not a count of independent experiments.

Provenance

Source examples

abacavir · bioavailability · agree

15 documents examined; 83% (Unknown: population and formulation context were not structurally extracted from this source sentence.)

FDA_LABEL:5676d391-f9a4-44be-9604-954b3d8d0e2b (opens source in a new tab)
The geometric mean absolute bioavailability of the tablet was 83%.

alemtuzumab · volumeOfDistribution · not_comparable

2 documents examined; 0.18 L/kg (Unknown: population and formulation context were not structurally extracted from this source sentence.); 14.1 L (Unknown: population and formulation context were not structurally extracted from this source sentence.)

FDA_LABEL:4f5f7255-7abc-4328-bd1a-ceaf139ef3e0 (opens source in a new tab)
Distribution After the last 30 mg dose, the mean volume of distribution at steady-state was 0.18 L/kg (range 0.1 to 0.4 L/kg).

abiraterone · halfLife · insufficient_context

31 documents examined; 12 ± 5 hours (Unknown: population and formulation context were not structurally extracted from this source sentence.); 18 hours (Unknown: population and formulation context were not structurally extracted from this source sentence.)

FDA_LABEL:c9eb9b46-f847-40a8-802c-a51b40406d5a (opens source in a new tab)
Elimination In patients with metastatic CRPC, the mean terminal half-life of abiraterone in plasma (mean ± SD) is 12 ± 5 hours.

Artifact used for this view: data/source-consensus.ndjson. The reader resolves the current run first and uses the checked-in compatibility run only when a current artifact is absent.

Schema

Fields in the public projection

FieldTypeMeaning
medicineSlugstringStable RNAWiki medicine route key.
fieldstringRecorded pharmacokinetic field being compared.
comparisonStatestringagree (printed-reading agreement), differ (context-matched comparable disjoint values), not_comparable (unit/denominator mismatch), or insufficient_context. Every state remains declared even when its current count is zero.
comparisonReasonsstring[]Deterministic codes explaining the state.
documentsExaminednumberRecorded source documents considered for the field.
sourceCountnumberRecorded source readings represented.
agreementRatenumberShare represented by the leading normalized printed-reading group; not a confidence score or clinical agreement probability.
readingsconsensus-reading[]Complete, untruncated reading groups. Each keeps the printed display, numeric value when parsed, unit, population context, source count, and every source identity, version/effective date or explicit absence, retrieval date, locator, safe link, and excerpt.

Reader

Search and filter the rows

Case-insensitive text search over the public fields named for this dataset.

Exact comparability state.

Exact recorded field key.

Clear

Showing 1,0911,100 of 1,681 matching rows. Filters and search terms remain attached when you move between pages or open the API view.

  1. Projected row 1091

    Medicine slug
    nilotinib
    Compared field
    proteinBinding
    Comparison state
    agree
    Reason codes
    • COMPATIBLE_VALUES_OVERLAP
    Documents examined
    11
    Source count
    11
    Agreement rate
    1
    Recorded readings
    1. 98%

      Numeric value
      98
      Unit
      %
      Source records
      11

      Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.

      Show all 11 source records
      1. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:13b46e09-62d2-4ce9-b3c0-deafcb1f1842 (opens source in a new tab)

        Nilotinib label

        Version not recorded · Effective date not recorded

        Serum protein binding is approximately 98%.
      2. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:6093952a-5248-45cb-ad17-33716a411146 (opens source in a new tab)

        Nilotinib label

        Version not recorded · Effective date not recorded

        Serum protein binding is approximately 98%.
      3. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:3c67b81f-9a44-446a-a24f-bbecbbf88979 (opens source in a new tab)

        Nilotinib label

        Version not recorded · Effective date not recorded

        Distribution Serum protein binding is approximately 98% with a blood-to-serum ratio of 0.68.
      4. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:805cc504-60bb-7743-5ada-679eb3badc7f (opens source in a new tab)

        Nilotinib label

        Version not recorded · Effective date not recorded

        Serum protein binding is approximately 98%.
      5. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:e27c3e09-bc4f-4f01-be05-1c43ac72285d (opens source in a new tab)

        Nilotinib label

        Version not recorded · Effective date not recorded

        Distribution Serum protein binding is approximately 98% with a blood-to-serum ratio of 0.68.
      6. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:86dc5507-ae0a-43d2-8d5e-5b0568ce9c5e (opens source in a new tab)

        Nilotinib label

        Version not recorded · Effective date not recorded

        Serum protein binding is approximately 98%.
      7. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:b34e7fd4-53c5-46d8-bf8a-1fcbe7a16504 (opens source in a new tab)

        Nilotinib label

        Version not recorded · Effective date not recorded

        Serum protein binding is approximately 98%.
      8. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:8283672c-619f-fe60-3d25-040f95ac1440 (opens source in a new tab)

        Nilotinib label

        Version not recorded · Effective date not recorded

        Serum protein binding is approximately 98%.
      9. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:d288d165-3505-49bb-9b2e-124490d65f49 (opens source in a new tab)

        Nilotinib label

        Version not recorded · Effective date not recorded

        Distribution Serum protein binding is approximately 98% with a blood-to-serum ratio of 0.68.
      10. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:98b197ea-bca4-427e-8737-97f70a3262bc (opens source in a new tab)

        Nilotinib label

        Version not recorded · Effective date not recorded

        Serum protein binding is approximately 98%.
      11. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:4c0bc799-ce6a-822a-e063-6394a90ab748 (opens source in a new tab)

        Nilotinib label

        Version not recorded · Effective date not recorded

        Serum protein binding is approximately 98%.
  2. Projected row 1092

    Medicine slug
    nilotinib
    Compared field
    tMax
    Comparison state
    insufficient_context
    Reason codes
    • STRUCTURED_CONTEXT_MISSING
    Documents examined
    11
    Source count
    10
    Agreement rate
    0.7
    Recorded readings
    1. 3 hours

      Numeric value
      3
      Unit
      hours
      Source records
      7

      Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.

      Show all 7 source records
      1. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:13b46e09-62d2-4ce9-b3c0-deafcb1f1842 (opens source in a new tab)

        Nilotinib label

        Version not recorded · Effective date not recorded

        Peak concentrations of nilotinib are reached 3 hours after oral administration.
      2. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:6093952a-5248-45cb-ad17-33716a411146 (opens source in a new tab)

        Nilotinib label

        Version not recorded · Effective date not recorded

        Peak concentrations of nilotinib are reached 3 hours after oral administration.
      3. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:805cc504-60bb-7743-5ada-679eb3badc7f (opens source in a new tab)

        Nilotinib label

        Version not recorded · Effective date not recorded

        Peak concentrations of nilotinib are reached 3 hours after oral administration.
      4. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:86dc5507-ae0a-43d2-8d5e-5b0568ce9c5e (opens source in a new tab)

        Nilotinib label

        Version not recorded · Effective date not recorded

        Peak concentrations of nilotinib are reached 3 hours after oral administration.
      5. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:b34e7fd4-53c5-46d8-bf8a-1fcbe7a16504 (opens source in a new tab)

        Nilotinib label

        Version not recorded · Effective date not recorded

        Peak concentrations of nilotinib are reached 3 hours after oral administration.
      6. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:8283672c-619f-fe60-3d25-040f95ac1440 (opens source in a new tab)

        Nilotinib label

        Version not recorded · Effective date not recorded

        Peak concentrations of nilotinib are reached 3 hours after oral administration.
      7. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:4c0bc799-ce6a-822a-e063-6394a90ab748 (opens source in a new tab)

        Nilotinib label

        Version not recorded · Effective date not recorded

        Peak concentrations of nilotinib are reached 3 hours after oral administration.
    2. 3.3 hours

      Numeric value
      3.3
      Unit
      hours
      Source records
      2

      Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.

      Show all 2 source records
      1. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:3c67b81f-9a44-446a-a24f-bbecbbf88979 (opens source in a new tab)

        Nilotinib label

        Version not recorded · Effective date not recorded

        Absorption The median time (range) to reach peak plasma nilotinib concentrations (Tmax) is 3.3 hours (1.0 to 5.5) following single dose administration of Nilotinib Capsules 200 mg (0.5 times the maximum approved recommended dose) in fasted healthy subjects.
      2. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:e27c3e09-bc4f-4f01-be05-1c43ac72285d (opens source in a new tab)

        Nilotinib label

        Version not recorded · Effective date not recorded

        Absorption The median time (range) to reach peak plasma nilotinib concentrations (Tmax) is 3.3 hours (1.0 to 5.5) following single dose administration of Nilotinib Capsules 200 mg (0.5 times the maximum approved recommended dose) in fasted healthy subjects.
    3. 2 hours

      Numeric value
      2
      Unit
      hours
      Source records
      1

      Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.

      Show all 1 source records
      1. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:98b197ea-bca4-427e-8737-97f70a3262bc (opens source in a new tab)

        Nilotinib label

        Version not recorded · Effective date not recorded

        The median time (range) to reach maximal plasma concentration (T max ) of nilotinib is 2 hours (1-8 hours) in the fasted state after oral administration.
  3. Projected row 1093

    Medicine slug
    nimodipine
    Compared field
    bioavailability
    Comparison state
    agree
    Reason codes
    • COMPATIBLE_VALUES_OVERLAP
    Documents examined
    4
    Source count
    4
    Agreement rate
    1
    Recorded readings
    1. 13%

      Numeric value
      13
      Unit
      %
      Source records
      4

      Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.

      Show all 4 source records
      1. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:a323ebd8-ef1b-439b-93d1-ba73a5b0127d (opens source in a new tab)

        Nimodipine label

        Version not recorded · Effective date not recorded

        Because of a high first-pass metabolism, the bioavailability of nimodipine averages 13% after oral administration.
      2. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:e660fa26-b5c4-4d6d-8887-9e22b6666a10 (opens source in a new tab)

        Nimodipine label

        Version not recorded · Effective date not recorded

        Because of a high first-pass metabolism, the bioavailability of nimodipine averages 13% after oral administration.
      3. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:e65d5108-22a2-4d87-a78d-15606f3cc9e2 (opens source in a new tab)

        Nimodipine label

        Version not recorded · Effective date not recorded

        Because of a high first-pass metabolism, the bioavailability of nimodipine averages 13% after oral administration.
      4. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:f829de8b-fabd-4aec-ac8d-c9aaef7be55b (opens source in a new tab)

        Nimodipine label

        Version not recorded · Effective date not recorded

        Because of a high first-pass metabolism, the bioavailability of nimodipine averages 13% after oral administration.
  4. Projected row 1094

    Medicine slug
    nintedanib
    Compared field
    bioavailability
    Comparison state
    agree
    Reason codes
    • COMPATIBLE_VALUES_OVERLAP
    Documents examined
    11
    Source count
    11
    Agreement rate
    1
    Recorded readings
    1. 4.7%

      Numeric value
      4.7
      Unit
      %
      Source records
      11

      Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.

      Show all 11 source records
      1. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:da1c9f37-779e-4682-816f-93d0faa4cfc9 (opens source in a new tab)

        Nintedanib label

        Version not recorded · Effective date not recorded

        The absolute bioavailability of a 100 mg dose was 4.7% (90% CI: 3.62 to 6.08) in healthy volunteers.
      2. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:0e12f080-fcb4-465f-b988-4fa2c79f49aa (opens source in a new tab)

        Nintedanib label

        Version not recorded · Effective date not recorded

        The absolute bioavailability of a 100 mg dose was 4.7% (90% CI: 3.62 to 6.08) in healthy volunteers.
      3. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:b14164fb-0276-4ad1-a5ff-400ab9e292da (opens source in a new tab)

        Nintedanib label

        Version not recorded · Effective date not recorded

        The absolute bioavailability of a 100 mg dose was 4.7% (90% CI: 3.62 to 6.08) in healthy volunteers.
      4. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:572722d7-338a-e4d2-e063-6394a90a257c (opens source in a new tab)

        Nintedanib label

        Version not recorded · Effective date not recorded

        The absolute bioavailability of a 100 mg dose was 4.7% (90% CI: 3.62 to 6.08) in healthy volunteers.
      5. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:4ecf7f05-4a95-b98c-e063-6394a90ab896 (opens source in a new tab)

        Nintedanib label

        Version not recorded · Effective date not recorded

        The absolute bioavailability of a 100 mg dose was 4.7% (90% CI: 3.62 to 6.08) in healthy volunteers.
      6. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:88f8600d-0974-51ca-6f8e-28c48a379e08 (opens source in a new tab)

        Nintedanib label

        Version not recorded · Effective date not recorded

        The absolute bioavailability of a 100 mg dose was 4.7% (90% CI: 3.62 to 6.08) in healthy volunteers.
      7. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:b72b26c3-7731-80c0-734b-a5f53a1d89ae (opens source in a new tab)

        Nintedanib label

        Version not recorded · Effective date not recorded

        The absolute bioavailability of a 100 mg dose was 4.7% (90% CI: 3.62 to 6.08) in healthy volunteers.
      8. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:43dae004-eaf6-4411-8c3d-db7ab2c3b41e (opens source in a new tab)

        Nintedanib label

        Version not recorded · Effective date not recorded

        The absolute bioavailability of a 100 mg dose was 4.7% (90% CI: 3.62 to 6.08) in healthy volunteers.
      9. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:751c3473-35d6-47d6-b405-af16a989716c (opens source in a new tab)

        Nintedanib label

        Version not recorded · Effective date not recorded

        The absolute bioavailability of a 100 mg dose was 4.7% (90% CI: 3.62 to 6.08) in healthy volunteers.
      10. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:4d017c42-a823-452d-bc6f-0491dd9823e3 (opens source in a new tab)

        Nintedanib label

        Version not recorded · Effective date not recorded

        The absolute bioavailability of a 100 mg dose was 4.7% (90% CI: 3.62 to 6.08) in healthy volunteers.
      11. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:60d8104e-cb6c-4f4f-8159-95ed57346ffa (opens source in a new tab)

        Nintedanib label

        Version not recorded · Effective date not recorded

        The absolute bioavailability of a 100 mg dose was 4.7% (90% CI: 3.62 to 6.08) in healthy volunteers.
  5. Projected row 1095

    Medicine slug
    nintedanib
    Compared field
    halfLife
    Comparison state
    agree
    Reason codes
    • COMPATIBLE_VALUES_OVERLAP
    Documents examined
    11
    Source count
    11
    Agreement rate
    1
    Recorded readings
    1. 9.5 hours

      Numeric value
      9.5
      Unit
      hours
      Source records
      11

      Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.

      Show all 11 source records
      1. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:da1c9f37-779e-4682-816f-93d0faa4cfc9 (opens source in a new tab)

        Nintedanib label

        Version not recorded · Effective date not recorded

        Elimination The effective half-life of nintedanib in patients with IPF was 9.5 hours (gCV 31.9%).
      2. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:0e12f080-fcb4-465f-b988-4fa2c79f49aa (opens source in a new tab)

        Nintedanib label

        Version not recorded · Effective date not recorded

        Elimination The effective half-life of nintedanib in patients with IPF was 9.5 hours (gCV 31.9%).
      3. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:b14164fb-0276-4ad1-a5ff-400ab9e292da (opens source in a new tab)

        Nintedanib label

        Version not recorded · Effective date not recorded

        Elimination The effective half-life of nintedanib in patients with IPF was 9.5 hours (gCV 31.9%).
      4. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:572722d7-338a-e4d2-e063-6394a90a257c (opens source in a new tab)

        Nintedanib label

        Version not recorded · Effective date not recorded

        Elimination The effective half-life of nintedanib in patients with IPF was 9.5 hours (gCV 31.9%).
      5. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:4ecf7f05-4a95-b98c-e063-6394a90ab896 (opens source in a new tab)

        Nintedanib label

        Version not recorded · Effective date not recorded

        Elimination The effective half-life of nintedanib in patients with IPF was 9.5 hours (gCV 31.9%).
      6. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:88f8600d-0974-51ca-6f8e-28c48a379e08 (opens source in a new tab)

        Nintedanib label

        Version not recorded · Effective date not recorded

        Elimination The effective half-life of nintedanib in patients with IPF was 9.5 hours (gCV 31.9%).
      7. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:b72b26c3-7731-80c0-734b-a5f53a1d89ae (opens source in a new tab)

        Nintedanib label

        Version not recorded · Effective date not recorded

        Elimination The effective half-life of nintedanib in patients with IPF was 9.5 hours (gCV 31.9%).
      8. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:43dae004-eaf6-4411-8c3d-db7ab2c3b41e (opens source in a new tab)

        Nintedanib label

        Version not recorded · Effective date not recorded

        Elimination The effective half-life of nintedanib in patients with IPF was 9.5 hours (gCV 31.9%).
      9. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:751c3473-35d6-47d6-b405-af16a989716c (opens source in a new tab)

        Nintedanib label

        Version not recorded · Effective date not recorded

        Elimination The effective half-life of nintedanib in patients with IPF was 9.5 hours (gCV 31.9%).
      10. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:4d017c42-a823-452d-bc6f-0491dd9823e3 (opens source in a new tab)

        Nintedanib label

        Version not recorded · Effective date not recorded

        Elimination The effective half-life of nintedanib in patients with IPF was 9.5 hours (gCV 31.9%).
      11. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:60d8104e-cb6c-4f4f-8159-95ed57346ffa (opens source in a new tab)

        Nintedanib label

        Version not recorded · Effective date not recorded

        Elimination The effective half-life of nintedanib in patients with IPF was 9.5 hours (gCV 31.9%).
  6. Projected row 1096

    Medicine slug
    nintedanib
    Compared field
    volumeOfDistribution
    Comparison state
    insufficient_context
    Reason codes
    • STRUCTURED_CONTEXT_MISSING
    Documents examined
    11
    Source count
    11
    Agreement rate
    0.818182
    Recorded readings
    1. 1050 L

      Numeric value
      1,050
      Unit
      L
      Source records
      9

      Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.

      Show all 9 source records
      1. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:da1c9f37-779e-4682-816f-93d0faa4cfc9 (opens source in a new tab)

        Nintedanib label

        Version not recorded · Effective date not recorded

        After intravenous infusion, a high volume of distribution which was larger than total body volume (V ss : 1050 L) was observed.
      2. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:0e12f080-fcb4-465f-b988-4fa2c79f49aa (opens source in a new tab)

        Nintedanib label

        Version not recorded · Effective date not recorded

        After intravenous infusion, a high volume of distribution which was larger than total body volume (Vss: 1050 L) was observed.
      3. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:b14164fb-0276-4ad1-a5ff-400ab9e292da (opens source in a new tab)

        Nintedanib label

        Version not recorded · Effective date not recorded

        After intravenous infusion, a high volume of distribution which was larger than total body volume (V ss : 1050 L) was observed.
      4. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:572722d7-338a-e4d2-e063-6394a90a257c (opens source in a new tab)

        Nintedanib label

        Version not recorded · Effective date not recorded

        After intravenous infusion, a high volume of distribution which was larger than total body volume (V ss : 1050 L) was observed.
      5. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:4ecf7f05-4a95-b98c-e063-6394a90ab896 (opens source in a new tab)

        Nintedanib label

        Version not recorded · Effective date not recorded

        After intravenous infusion, a high volume of distribution which was larger than total body volume (V ss : 1050 L) was observed.
      6. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:43dae004-eaf6-4411-8c3d-db7ab2c3b41e (opens source in a new tab)

        Nintedanib label

        Version not recorded · Effective date not recorded

        After intravenous infusion, a high volume of distribution which was larger than total body volume (V ss : 1050 L) was observed.
      7. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:751c3473-35d6-47d6-b405-af16a989716c (opens source in a new tab)

        Nintedanib label

        Version not recorded · Effective date not recorded

        After intravenous infusion, a high volume of distribution which was larger than total body volume (V ss : 1050 L) was observed.
      8. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:4d017c42-a823-452d-bc6f-0491dd9823e3 (opens source in a new tab)

        Nintedanib label

        Version not recorded · Effective date not recorded

        After intravenous infusion, a high volume of distribution which was larger than total body volume (V ss : 1050 L) was observed.
      9. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:60d8104e-cb6c-4f4f-8159-95ed57346ffa (opens source in a new tab)

        Nintedanib label

        Version not recorded · Effective date not recorded

        After intravenous infusion, a high volume of distribution which was larger than total body volume (V ss : 1050 L) was observed.
    2. 1,050 L

      Numeric value
      1,050
      Unit
      L
      Source records
      2

      Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.

      Show all 2 source records
      1. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:88f8600d-0974-51ca-6f8e-28c48a379e08 (opens source in a new tab)

        Nintedanib label

        Version not recorded · Effective date not recorded

        After intravenous infusion, a high volume of distribution which was larger than total body volume (Vss: 1,050 L) was observed.
      2. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:b72b26c3-7731-80c0-734b-a5f53a1d89ae (opens source in a new tab)

        Nintedanib label

        Version not recorded · Effective date not recorded

        After intravenous infusion, a high volume of distribution which was larger than total body volume (V ss : 1,050 L) was observed.
  7. Projected row 1097

    Medicine slug
    nisoldipine
    Compared field
    bioavailability
    Comparison state
    agree
    Reason codes
    • COMPATIBLE_VALUES_OVERLAP
    Documents examined
    3
    Source count
    3
    Agreement rate
    1
    Recorded readings
    1. 5%

      Numeric value
      5
      Unit
      %
      Source records
      3

      Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.

      Show all 3 source records
      1. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:8a5fb6a2-9fae-4872-8c5c-0f1ba03a57cb (opens source in a new tab)

        Nisoldipine label

        Version not recorded · Effective date not recorded

        The absolute bioavailability of nisoldipine is about 5%.
      2. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:589157fa-d129-4de3-be3d-e0e1c22c5873 (opens source in a new tab)

        Nisoldipine label

        Version not recorded · Effective date not recorded

        The absolute bioavailability of nisoldipine is about 5%.
      3. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:a52b773a-44f9-442f-a4be-39f79a558bd2 (opens source in a new tab)

        Nisoldipine label

        Version not recorded · Effective date not recorded

        The absolute bioavailability of nisoldipine is about 5%.
  8. Projected row 1098

    Medicine slug
    nitazoxanide
    Compared field
    bioavailability
    Comparison state
    agree
    Reason codes
    • COMPATIBLE_VALUES_OVERLAP
    Documents examined
    4
    Source count
    4
    Agreement rate
    1
    Recorded readings
    1. 70%

      Numeric value
      70
      Unit
      %
      Source records
      4

      Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.

      Show all 4 source records
      1. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:c0dc0656-3c46-43f9-adea-5285c522cef8 (opens source in a new tab)

        Nitazoxanide label

        Version not recorded · Effective date not recorded

        The relative bioavailability of the suspension compared to the tablet was 70%.
      2. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:cd3652fa-a183-4fb6-9a21-73fbeba6fc4b (opens source in a new tab)

        Nitazoxanide label

        Version not recorded · Effective date not recorded

        The relative bioavailability of the suspension compared to the tablet was 70%.
      3. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:40a7cc30-76cd-49fe-965a-7823c4140d0f (opens source in a new tab)

        Nitazoxanide label

        Version not recorded · Effective date not recorded

        The relative bioavailability of the suspension compared to the tablet was 70%.
      4. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:295011e1-f919-4e5a-b9e7-4c784f623a86 (opens source in a new tab)

        Nitazoxanide label

        Version not recorded · Effective date not recorded

        The relative bioavailability of the suspension compared to the tablet was 70%.
  9. Projected row 1099

    Medicine slug
    nitisinone
    Compared field
    halfLife
    Comparison state
    agree
    Reason codes
    • COMPATIBLE_VALUES_OVERLAP
    Documents examined
    10
    Source count
    8
    Agreement rate
    1
    Recorded readings
    1. 54 hours

      Numeric value
      54
      Unit
      hours
      Source records
      8

      Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.

      Show all 8 source records
      1. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:b7c38003-6899-4508-a69a-aef1231de22c (opens source in a new tab)

        Nitisinone label

        Version not recorded · Effective date not recorded

        Elimination The mean terminal plasma half-life of single dose nitisinone in healthy male subjects is 54 hours.
      2. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:645c8387-30d5-4a86-a5d8-2f6b5df6d5f0 (opens source in a new tab)

        Nitisinone label

        Version not recorded · Effective date not recorded

        Elimination The mean terminal plasma half-life of single dose nitisinone in healthy male subjects is 54 hours.
      3. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:5d449b73-d503-4132-b978-d890491975df (opens source in a new tab)

        Nitisinone label

        Version not recorded · Effective date not recorded

        Elimination The mean terminal plasma half-life of single dose nitisinone in healthy male subjects is 54 hours.
      4. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:dc5e4875-fcd7-408c-88c9-4a715f4384b6 (opens source in a new tab)

        Nitisinone label

        Version not recorded · Effective date not recorded

        Elimination The mean terminal plasma half-life of single dose nitisinone in healthy male subjects is 54 hours.
      5. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:8cec0318-9f55-4340-b14b-588635619251 (opens source in a new tab)

        Nitisinone label

        Version not recorded · Effective date not recorded

        Elimination The mean terminal plasma half-life of single dose nitisinone in healthy male subjects is 54 hours.
      6. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:437868f5-1c9e-4b0f-8a03-77df8ac0900d (opens source in a new tab)

        Nitisinone label

        Version not recorded · Effective date not recorded

        Elimination The mean terminal plasma half-life of single dose nitisinone in healthy male subjects is 54 hours.
      7. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:c1b3adc8-02fa-4e22-8c05-8f32b586e53f (opens source in a new tab)

        Nitisinone label

        Version not recorded · Effective date not recorded

        Elimination The mean terminal plasma half-life of single dose nitisinone in healthy male subjects is 54 hours.
      8. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:00307f42-748d-4227-8c6f-ed5f0a89ae0a (opens source in a new tab)

        Nitisinone label

        Version not recorded · Effective date not recorded

        Elimination The mean terminal plasma half-life of single dose nitisinone in healthy male subjects is 54 hours.
  10. Projected row 1100

    Medicine slug
    nitisinone
    Compared field
    tMax
    Comparison state
    insufficient_context
    Reason codes
    • STRUCTURED_CONTEXT_MISSING
    Documents examined
    10
    Source count
    3
    Agreement rate
    0.666667
    Recorded readings
    1. 3 hours

      Numeric value
      3
      Unit
      hours
      Source records
      2

      Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.

      Show all 2 source records
      1. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:5d449b73-d503-4132-b978-d890491975df (opens source in a new tab)

        Nitisinone label

        Version not recorded · Effective date not recorded

        Compared to ORFADIN capsule, the median T max occurred about 3 hours earlier with ORFADIN oral suspension.
      2. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:00307f42-748d-4227-8c6f-ed5f0a89ae0a (opens source in a new tab)

        Nitisinone label

        Version not recorded · Effective date not recorded

        Compared to ORFADIN capsule, the median T max occurred about 3 hours earlier with ORFADIN oral suspension.
    2. 3.5 hours

      Numeric value
      3.5
      Unit
      hours
      Source records
      1

      Population and context: Unknown: population and formulation context were not structurally extracted from this source sentence.

      Show all 1 source records
      1. FDA_LABELRetrieved 2026-08-30
        FDA_LABEL:7cf67e24-d46b-4376-bbd0-0b973c406d0d (opens source in a new tab)

        Nitisinone label

        Version not recorded · Effective date not recorded

        Absorption Nitisinone time to C max (T max ) is 3.5 hours (median, ranging from 1 to 4 hours) following single oral administration of 10 mg (5 times the recommended dosage) nitisinone under fasting conditions.

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state
Exact comparability state.Values: agree, differ, not_comparable, insufficient_context
field
Exact recorded field key.Values: bioavailability, halfLife, proteinBinding, tMax, volumeOfDistribution
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