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Recorded silence and non-establishment

Show, for each medicine and tracked question, whether the recorded source sections contain an answer, explicitly say the question is not established, or stay silent.

What this does not mean: SILENT means only that this corpus did not record an answer from the sections it read. It is not evidence of safety, danger, or real-world absence. NOT_ESTABLISHED is an explicit source state and must not be collapsed into silence.
Public rows
167,535
Generated
Schema version
1.2.0

Coverage

What this run contains

Medicine-question rows
167,535
Medicines
9,855
Questions
17
Recorded
19,750
Not established
1,463
Silent
146,322
explicit not established
1,463
source read no answer
0
no qualifying source read
146,322
source kind not machine verifiable
0
source recorded no qualifying read
0

Method

How the rows were made

  1. A fixed 17-question set is applied deterministically to each medicine record.
  2. RECORDED, NOT_ESTABLISHED, and SILENT remain distinct. Population mentions without a finding stay RECORDED but carry mentionedWithoutFinding=true.
  3. Each row is joined only when the ledger persists a source identifier for that occurrence and the same source object is attached to that exact question field or statement collection. An excerpt elsewhere in the medicine envelope cannot establish that this question was read.
  4. A source counts only when its kind, identifier, label, and retrieval date satisfy the checked-in background-source contract. SOURCE_READ_NO_ANSWER additionally requires that exact persisted binding, a nonblank excerpt, and a canonical machine-verifiable locator.
  5. This projection includes every medicine-question pair, every source identifier emitted by the ledger, and the complete exact-scope source records; it does not copy review-work fields.

Limits

Read these before using a row

  • SILENT means no source in this corpus, in the sections that were read, states an answer. It is a fact about the documents recorded here and never a fact about the medicine.
  • A record silent on a question is not evidence that no answer exists, and it is not evidence of safety or of danger in either direction. A label that never states a pediatric half-life is a label that never states one, nothing more.
  • Section scoping is a real limit. A fact can sit in a section the extractor does not read, so every silence count should be read as "not recorded from the sections read" rather than "not stated anywhere".
  • Silence on the boxed-warning question is the clearest case of this: 9183 of 9855 records hold no boxed-warning statement, which means no recorded document contributed one, not that no boxed warning exists.
  • Only the 6 population questions can show NOT_ESTABLISHED, because only population statements carry a source-stated evidence state. On the other 11 questions a source sentence saying something was never determined, if one was printed, arrives here as a plain absence and is counted as SILENT.
  • 3278 of 9855 records were produced by the deterministic label parser rather than assembled by a person. The parser reads a fixed set of sections, so its silences are more often a limit of the parser than of the source; the roll-up splits recorded and silent counts by tier so the two are never added together blindly.
  • RECORDED on a population question merges two different answers: a source reporting a finding in the group, and a source that only raises the group without settling safety or effectiveness for it. 88% of recorded population answers here are the second kind, so a high recorded share on those questions is not a high share of settled answers. Entries of the second kind carry mentionedWithoutFinding and the roll-up counts them in recordedMentionOnly.
  • Where the recorded statements for one population disagree, one saying a group was studied and another saying the question was not established, the entry counts as RECORDED and is marked as holding mixed states. The disagreement is recorded and is not settled here.
  • Counts are over the records this corpus holds, which is neither every medicine nor every revision of every document. The recorded share of a question is a property of this corpus on this run date.
  • A source object without an excerpt is provenance, not proof that the exact section was read. It therefore cannot become SOURCE_READ_NO_ANSWER.
  • An excerpt attached to another question or module is unrelated evidence for this classification and is never used to label this row as read.
  • The current ledger does not persist a section-read binding for SILENT occurrences, so those rows remain NO_QUALIFYING_SOURCE_READ. SOURCE_READ_NO_ANSWER stays empty until a future artifact records an exact question-and-source binding; answer-bearing consensus evidence is never repurposed as proof of silence.
  • SOURCE_KIND_NOT_MACHINE_VERIFIABLE reports only the absence of a canonical locator in the checked-in source-fetch contract. It does not judge the source itself.

Provenance

Source examples

Abaloparatide · population_pediatric · NOT_ESTABLISHED

EXPLICIT_NOT_ESTABLISHED. Do the recorded documents address a pediatric population?

FDA_LABEL:712143d9-e21e-4013-bb3b-3426a21060a8

0.01-0.2 Mole Percent Bisacrylamide) · half_life · SILENT

NO_QUALIFYING_SOURCE_READ. Do the recorded documents state an elimination half-life?

Artifact used for this view: data/agents/current/silence-ledger.json + data/recorded-background.ndjson. The reader resolves the current run first and uses the checked-in compatibility run only when a current artifact is absent.

Schema

Fields in the public projection

FieldTypeMeaning
medicineSlugstringStable RNAWiki medicine route key.
medicineNamestringRecorded medicine name.
questionIdstringStable identifier from the fixed question set.
questionstringThe exact corpus-coverage question.
modulestringRecorded-background module checked for an answer.
statestringRECORDED, NOT_ESTABLISHED, or SILENT.
silenceMeaningstringExplicit non-establishment or the exact source-read boundary behind SILENT; null for RECORDED.
mentionedWithoutFindingbooleanTrue when a population was mentioned without a settled finding.
sourceIdentifiersstring[]Exact recorded source bindings; empty for SILENT.
scopedSourcessource[]Complete valid source objects attached to this exact question field or statement collection, including version/effective date or explicit absence, with safe allowlisted links when a canonical adapter exists.
recordedSourceCountnumberDistinct qualifying source kind-and-identifier pairs attached to this exact question scope.
recordedSourceKindsstring[]Qualifying source kinds attached to this exact question scope.
machineVerifiableSourceKindsstring[]Exact-scope recorded kinds for which the checked-in source-fetch contract defines a canonical locator.

Reader

Search and filter the rows

Case-insensitive text search over the public fields named for this dataset.

Exact state; NOT_ESTABLISHED is never treated as SILENT.

Exact derived source-read boundary; RECORDED rows have no silence meaning.

Exact question identifier.

Clear

Showing 21–30 of 167,535 matching rows. Filters and search terms remain attached when you move between pages or open the API view.

  1. Projected row 21

    Medicine slug
    1-2-distearoyl-sn-glycero-3-phosphocholine
    Medicine name
    1,2-Distearoyl-Sn-Glycero-3-Phosphocholine
    Question key
    protein_binding
    Question
    Do the recorded documents state plasma protein binding?
    Module
    pharmacokinetics.proteinBinding
    State
    SILENT
    Silence meaning
    NO_QUALIFYING_SOURCE_READ
    Mention only
    No
    Source identifiers
    None recorded
    Exact question sources
    None recorded
    Recorded source documents
    0
    Recorded source kinds
    None recorded
    Machine-verifiable source kinds
    None recorded

  2. Projected row 22

    Medicine slug
    1-2-distearoyl-sn-glycero-3-phosphocholine
    Medicine name
    1,2-Distearoyl-Sn-Glycero-3-Phosphocholine
    Question key
    volume_of_distribution
    Question
    Do the recorded documents state a volume of distribution?
    Module
    pharmacokinetics.volumeOfDistribution
    State
    SILENT
    Silence meaning
    NO_QUALIFYING_SOURCE_READ
    Mention only
    No
    Source identifiers
    None recorded
    Exact question sources
    None recorded
    Recorded source documents
    0
    Recorded source kinds
    None recorded
    Machine-verifiable source kinds
    None recorded

  3. Projected row 23

    Medicine slug
    1-2-distearoyl-sn-glycero-3-phosphocholine
    Medicine name
    1,2-Distearoyl-Sn-Glycero-3-Phosphocholine
    Question key
    mechanism_of_action
    Question
    Do the recorded documents describe how the medicine acts?
    Module
    mechanism.statements
    State
    SILENT
    Silence meaning
    NO_QUALIFYING_SOURCE_READ
    Mention only
    No
    Source identifiers
    None recorded
    Exact question sources
    None recorded
    Recorded source documents
    0
    Recorded source kinds
    None recorded
    Machine-verifiable source kinds
    None recorded

  4. Projected row 24

    Medicine slug
    1-2-distearoyl-sn-glycero-3-phosphocholine
    Medicine name
    1,2-Distearoyl-Sn-Glycero-3-Phosphocholine
    Question key
    molecular_identity
    Question
    Do the recorded documents state a molecular formula or molecular weight?
    Module
    molecularIdentity
    State
    RECORDED
    Silence meaning
    Not recorded
    Mention only
    No
    Source identifiers
    • PUBCHEM:94190
    Exact question sources
    1. PUBCHEMRetrieved 2026-08-29
      PUBCHEM:94190 (opens source in a new tab)

      Compound record for 1,2-Distearoyl-Sn-Glycero-3-Phosphocholine

      Version not recorded · Effective date not recorded

    Recorded source documents
    1
    Recorded source kinds
    • PUBCHEM
    Machine-verifiable source kinds
    • PUBCHEM

  5. Projected row 25

    Medicine slug
    1-2-distearoyl-sn-glycero-3-phosphocholine
    Medicine name
    1,2-Distearoyl-Sn-Glycero-3-Phosphocholine
    Question key
    metabolic_handling
    Question
    Do the recorded documents name an enzyme or transporter that handles the medicine?
    Module
    interactionSignals
    State
    SILENT
    Silence meaning
    NO_QUALIFYING_SOURCE_READ
    Mention only
    No
    Source identifiers
    None recorded
    Exact question sources
    None recorded
    Recorded source documents
    0
    Recorded source kinds
    None recorded
    Machine-verifiable source kinds
    None recorded

  6. Projected row 26

    Medicine slug
    1-2-distearoyl-sn-glycero-3-phosphocholine
    Medicine name
    1,2-Distearoyl-Sn-Glycero-3-Phosphocholine
    Question key
    boxed_warning
    Question
    Do the recorded documents carry a boxed warning?
    Module
    safety.boxedWarning
    State
    SILENT
    Silence meaning
    NO_QUALIFYING_SOURCE_READ
    Mention only
    No
    Source identifiers
    None recorded
    Exact question sources
    None recorded
    Recorded source documents
    0
    Recorded source kinds
    None recorded
    Machine-verifiable source kinds
    None recorded

  7. Projected row 27

    Medicine slug
    1-2-distearoyl-sn-glycero-3-phosphocholine
    Medicine name
    1,2-Distearoyl-Sn-Glycero-3-Phosphocholine
    Question key
    contraindications
    Question
    Do the recorded documents list contraindications?
    Module
    safety.contraindications
    State
    SILENT
    Silence meaning
    NO_QUALIFYING_SOURCE_READ
    Mention only
    No
    Source identifiers
    None recorded
    Exact question sources
    None recorded
    Recorded source documents
    0
    Recorded source kinds
    None recorded
    Machine-verifiable source kinds
    None recorded

  8. Projected row 28

    Medicine slug
    1-2-distearoyl-sn-glycero-3-phosphocholine
    Medicine name
    1,2-Distearoyl-Sn-Glycero-3-Phosphocholine
    Question key
    most_common_adverse_reactions
    Question
    Do the recorded documents list the most common adverse reactions?
    Module
    commonAdverseReactions
    State
    SILENT
    Silence meaning
    NO_QUALIFYING_SOURCE_READ
    Mention only
    No
    Source identifiers
    None recorded
    Exact question sources
    None recorded
    Recorded source documents
    0
    Recorded source kinds
    None recorded
    Machine-verifiable source kinds
    None recorded

  9. Projected row 29

    Medicine slug
    1-2-distearoyl-sn-glycero-3-phosphocholine
    Medicine name
    1,2-Distearoyl-Sn-Glycero-3-Phosphocholine
    Question key
    population_pediatric
    Question
    Do the recorded documents address a pediatric population?
    Module
    populationStatements[PEDIATRIC]
    State
    SILENT
    Silence meaning
    NO_QUALIFYING_SOURCE_READ
    Mention only
    No
    Source identifiers
    None recorded
    Exact question sources
    None recorded
    Recorded source documents
    0
    Recorded source kinds
    None recorded
    Machine-verifiable source kinds
    None recorded

  10. Projected row 30

    Medicine slug
    1-2-distearoyl-sn-glycero-3-phosphocholine
    Medicine name
    1,2-Distearoyl-Sn-Glycero-3-Phosphocholine
    Question key
    population_geriatric
    Question
    Do the recorded documents address a geriatric population?
    Module
    populationStatements[GERIATRIC]
    State
    SILENT
    Silence meaning
    NO_QUALIFYING_SOURCE_READ
    Mention only
    No
    Source identifiers
    None recorded
    Exact question sources
    None recorded
    Recorded source documents
    0
    Recorded source kinds
    None recorded
    Machine-verifiable source kinds
    None recorded

Access

Query or download the projection

View this filtered page as JSONDownload up to 200 filtered CSV rows
GET /api/datasets/silence-ledger?limit=10&offset=20

Allowed query parameters

q
Case-insensitive text search over the public fields named for this dataset.
state
Exact state; NOT_ESTABLISHED is never treated as SILENT.Values: RECORDED, NOT_ESTABLISHED, SILENT
meaning
Exact derived source-read boundary; RECORDED rows have no silence meaning.Values: EXPLICIT_NOT_ESTABLISHED, SOURCE_READ_NO_ANSWER, NO_QUALIFYING_SOURCE_READ, SOURCE_KIND_NOT_MACHINE_VERIFIABLE, SOURCE_RECORDED_NO_QUALIFYING_READ
field
Exact question identifier.Values: half_life, bioavailability, t_max, protein_binding, volume_of_distribution, mechanism_of_action, molecular_identity, metabolic_handling, boxed_warning, contraindications, most_common_adverse_reactions, population_pediatric, population_geriatric, population_pregnancy, population_lactation, population_hepatic_impairment, population_renal_impairment
limit / offset
Pagination is required. limit is at most 200; offset is bounded. Set format=csv for the same projected page as a download.

Reuse and corrections

Keep the boundary attached

CC BY 4.0 applies to RNAWiki licenses its selection, schema, structure, and derived projection. Quoted source passages and third-party records retain their original rights.

Cite RNAWiki, this dataset identifier, and the generated date. Keep the “does not mean” statement with any downstream display so a corpus measurement is not mistaken for medical advice.

Read the correction policy