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Zinc Sulfate Anhydrous

  • Prescription medicine
  • Prescription only
  • Identity checked
  • Sources last checked 2026-09-04

This page shows what was measured, who it was measured in, and what that does not settle.

What Zinc Sulfate Anhydrous does in the body

Zinc sulfate injection is indicated in adult and pediatric patients as a source of zinc for parenteral nutrition when oral or enteral nutrition is not possible, insufficient, or contraindicated.

Zinc functions as a cofactor of various enzymes including DNA polymerases, RNA polymerases, alcohol dehydrogenase, and alkaline phosphatases. Zinc is a coordinator of protein structural folding, such as folding of “Zinc finger” motif that interacts with a variety of proteins, lipids, and nucleic acids. In addition, zinc is a catalyst of essential biochemical reactions, including activation of substrates of carbonic anhydrase in erythrocyte. Also, zinc is a signaling mediator modulating multiple signaling pathways.

Why people take it. Zinc sulfate injection is indicated in adult and pediatric patients as a source of zinc for parenteral nutrition when oral or enteral nutrition is not possible, insufficient, or contraindicated.

What happened in people

RNAWiki has not yet published a reviewed conclusion for this use.

A fixed RNAWiki sentence

Where this came from

Wording RNAWiki always uses, not a finding about this substance.

No reviewed claim names a result for any goal on this record.

No source is stored against this line.

The limit that matters most

Not recorded.

Where it acts
Not recorded.
Kind of result
No result is published, so no kind of result applies yet
Supervision
RNAWiki has not recorded a supervision or regulatory status for this substance.

What the registries record it as

  • The substance registry classes this as mixture.

    FDA substance registry · 89DS0H96TB · read 2026-08-29

Where each sentence above came from

The use the label states, quoted from it. No plain-language version of this sentence has been written.

The use the label states, quoted from it. It is written for a clinician, not for a reader without medical training.

No statement of the main limit is recorded.

The four opening statements run to 142 words.

Words this page uses

Four words worth knowing first

Chosen from what this page shows, with each one explained before the word it depends on.

Biomarker

A biomarker is a number from a test that stands in for something about health.

A picture of it, and where the picture fails

A biomarker is like a fuel gauge.

Where that stops being true. A gauge is wired to the tank. Many biomarkers are only loosely tied to health.

What people get wrong. A better number is read as a better life. Several medicines improved a number and helped nobody.

A measurable indicator used as a substitute for a clinical outcome of interest.

Placebo

A placebo is a dummy treatment given so the real one can be compared with it.

A picture of it, and where the picture fails

A placebo is like a blank control in an experiment.

Where that stops being true. A blank does nothing. People given a placebo often do get better.

What people get wrong. A placebo effect is read as imaginary. The improvement is measured and real.

An inactive intervention matched in appearance to the test intervention, used to control for non-specific effects.

Comparator

A comparator is whatever the treatment was measured against.

A picture of it, and where the picture fails

It is like the other runner in a race.

Where that stops being true. A race has one winner. A study can show both arms improved.

What people get wrong. Results are read without asking what the other group got. Beating nothing is not beating a treatment.

The control condition against which the experimental intervention is assessed.

What happened in peopleRead from sources, not yet reviewed

What happened in people

Each card is one study: the exact question it asked, who was in it, and whether it showed what it set out to show.

C-reactive protein mg/L

The study did not show it

Who was studied
NCT04301336
How many people
350
Study design
Phase 2/Phase 3
Compared against
Not recorded for this study
Kind of result
A number that stands in for health
What was found
Result not recorded on this page
Repeated elsewhere
Unreplicated

What this does not prove. A study that did not show an effect does not show that no effect exists anywhere.

The limits of this study, and where it came from

Main limit. No limitation is recorded for this study.

How far it carries. This study is recorded from the curated record, not from the registry match.

Form and route.

Interval reported. Not recorded in this summary

Written into the record, not signed off as a reviewed claim.

  • openFDA NDC Directory · a recorded source, not a stored snapshot
  • openFDA Drugs@FDA · a recorded source, not a stored snapshot
  • Europe PMC · a recorded source, not a stored snapshot

Change in WOMAC score at 24 months in comparison to baseline score

The study did not show it

Who was studied
NCT02178137
How many people
322
Study design
Phase 4
Compared against
Not recorded for this study
Kind of result
A number that stands in for health
What was found
Result not recorded on this page
Repeated elsewhere
Unreplicated

What this does not prove. A study that did not show an effect does not show that no effect exists anywhere.

The limits of this study, and where it came from

Main limit. No limitation is recorded for this study.

How far it carries. This study is recorded from the curated record, not from the registry match.

Form and route.

Interval reported. Not recorded in this summary

Written into the record, not signed off as a reviewed claim.

  • openFDA NDC Directory · a recorded source, not a stored snapshot
  • openFDA Drugs@FDA · a recorded source, not a stored snapshot
  • Europe PMC · a recorded source, not a stored snapshot

Comparison of Efficacy of the two different Zinc Sulphate formulations

The study did not show it

Who was studied
NCT00682955
How many people
300
Study design
Not applicable
Compared against
Not recorded for this study
Kind of result
A number that stands in for health
What was found
Result not recorded on this page
Repeated elsewhere
Unreplicated

What this does not prove. A study that did not show an effect does not show that no effect exists anywhere.

The limits of this study, and where it came from

Main limit. No limitation is recorded for this study.

How far it carries. This study is recorded from the curated record, not from the registry match.

Form and route.

Interval reported. Not recorded in this summary

Written into the record, not signed off as a reviewed claim.

  • openFDA NDC Directory · a recorded source, not a stored snapshot
  • openFDA Drugs@FDA · a recorded source, not a stored snapshot
  • Europe PMC · a recorded source, not a stored snapshot

Weight velocity during the date of start intervention until the end of the time interval (at least 2 weeks of intervention on date of 44 weeks of postmenstrual age or discharge whichever came first)

The study did not show it

Who was studied
NCT06219525
How many people
120
Study design
Not applicable
Compared against
Not recorded for this study
Kind of result
A number that stands in for health
What was found
Result not recorded on this page
Repeated elsewhere
Unreplicated

What this does not prove. A study that did not show an effect does not show that no effect exists anywhere.

The limits of this study, and where it came from

Main limit. No limitation is recorded for this study.

How far it carries. This study is recorded from the curated record, not from the registry match.

Form and route.

Interval reported. Not recorded in this summary

Written into the record, not signed off as a reviewed claim.

  • openFDA NDC Directory · a recorded source, not a stored snapshot
  • openFDA Drugs@FDA · a recorded source, not a stored snapshot
  • Europe PMC · a recorded source, not a stored snapshot

Postoperative morbidity

The study did not show it

Who was studied
NCT07210164
How many people
100
Study design
Not applicable
Compared against
Not recorded for this study
Kind of result
A number that stands in for health
What was found
Result not recorded on this page
Repeated elsewhere
Unreplicated

What this does not prove. A study that did not show an effect does not show that no effect exists anywhere.

The limits of this study, and where it came from

Main limit. No limitation is recorded for this study.

How far it carries. This study is recorded from the curated record, not from the registry match.

Form and route.

Interval reported. Not recorded in this summary

Written into the record, not signed off as a reviewed claim.

  • openFDA NDC Directory · a recorded source, not a stored snapshot
  • openFDA Drugs@FDA · a recorded source, not a stored snapshot
  • Europe PMC · a recorded source, not a stored snapshot

Severity of Post-Operative Sore Throat

The study did not show it

Who was studied
NCT02405832
How many people
87
Study design
Not applicable
Compared against
Not recorded for this study
Kind of result
A number that stands in for health
What was found
Result not recorded on this page
Repeated elsewhere
Unreplicated

What this does not prove. A study that did not show an effect does not show that no effect exists anywhere.

The limits of this study, and where it came from

Main limit. No limitation is recorded for this study.

How far it carries. This study is recorded from the curated record, not from the registry match.

Form and route.

Interval reported. Not recorded in this summary

Written into the record, not signed off as a reviewed claim.

  • openFDA NDC Directory · a recorded source, not a stored snapshot
  • openFDA Drugs@FDA · a recorded source, not a stored snapshot
  • Europe PMC · a recorded source, not a stored snapshot
What we know
RNAWiki holds 6 written-up human studies for this substance, each with the question it asked.
How we know it
Each card names the study, the number of people and what the study set out to measure.
What this does not prove
These summaries were written by a person and have not been signed off as reviewed claims.
Why it matters
A study that failed is as informative as one that worked, and both are here.
What we still do not know
No reviewed claim exists, so no exact population, effect size or interval is published yet.

What is missing or unclearRead from sources, not yet reviewed

Were people like you studied?

RNAWiki cannot tell whether a study fits you. It can show who was in it, and where the result stops carrying.

Who was studied

No description of who was studied is recorded.

Who is missing from the studies

  • Which groups were under-represented in the studies has not been recorded for this substance. Pregnancy, breastfeeding, children, older adults, and people with liver or kidney conditions are commonly excluded from trials; nothing here says whether they were.

What the label states about particular groups

  • On pediatric, the label states: “Zinc sulfate injection is approved for use in the pediatric population, including neonates, as a source of zinc for parenteral nutrition when oral or enteral nutrition is not possible, insufficient, or contraindicated.”

    US prescribing information · b9cf2dab-6ec8-e099-464a-af46a3601971 · read 2026-08-30

  • On older people, the label states: “Reported clinical experience with intravenous zinc sulfate has not identified a difference in zinc requirements between elderly and younger patients.”

    US prescribing information · b9cf2dab-6ec8-e099-464a-af46a3601971 · read 2026-08-30

  • On people who are pregnant, the label states: “Risk Summary Administration of the approved recommended dose of zinc sulfate injection in parenteral nutrition is not expected to cause major birth defects, miscarriage, or adverse maternal or fetal outcomes.”

    US prescribing information · b9cf2dab-6ec8-e099-464a-af46a3601971 · read 2026-08-30

  • On people who are breastfeeding, the label states: “Risk Summary Zinc is present in human milk.”

    US prescribing information · b9cf2dab-6ec8-e099-464a-af46a3601971 · read 2026-08-30

Where the result stopped carrying

  • This is a scope explorer, not a diagnosis engine.
  • It shows who was studied so you can see whether people similar to you were included.

RNAWiki cannot tell whether a study fits you. It can show who was in it.

What it would be like to takeRead from sources, not yet reviewed

Why it might seem to do nothing

A real effect and a noticed effect are different things. These are the recorded reasons the two come apart.

It was studied in different people

The people in the studies were not much like the reader.

On this record: Which groups were under-represented in the studies has not been recorded for this substance. Pregnancy, breastfeeding, children, older adults, and people with liver or kidney conditions are commonly excluded from trials; nothing here says whether they were.

The evidence may simply be wrong

Small early studies often do not hold up.

On this record: RNAWiki has not yet published a reviewed conclusion for this use.

Other reasons RNAWiki checked and found nothing for (11)
It was studied for a different goal
The studies measured something else entirely. Nothing in this record points to this reason.
A different form was studied
The studied form is not the form on the shelf. Nothing in this record points to this reason.
There was nothing to correct
Where a level is already normal, topping it up may change nothing. Nothing in this record points to this reason.
Something else had to happen too
In the studies it was paired with training, a diet or another treatment. Nothing in this record points to this reason.
The change is too small to feel
A real change can still sit below what a person notices. Nothing in this record points to this reason.
Day-to-day swing hides it
Sleep, food, stress and time of day move most numbers more than this would. Nothing in this record points to this reason.
Not enough time yet
The studies ran longer than the person has waited. Nothing in this record points to this reason.
It was not taken as studied
Missed days change the result, and studies count them. Nothing in this record points to this reason.
Something else changed at the same time
Two changes at once cannot be told apart afterwards. Nothing in this record points to this reason.
The product may not be what it says
Contents of a sold product are not always what the label states. Nothing in this record points to this reason.
No recorded reason
RNAWiki has nothing stored that would explain it. Nothing in this record points to this reason.

None of these is a reason to take more. Taking more is not a step this page ever suggests.

What it would be like to takeRead from sources, not yet reviewed

What taking it involves

The recorded facts about getting hold of it and using it. Nothing here is a suggestion about what you should do.

How it is supplied

Prescription only

Quoted from a source

Where this came from

Copied from a source RNAWiki stored, with the source named.

Read from the recorded approval status.

No source is stored against this line.

Form and route

Not recorded.

Nothing recorded

Where this came from

RNAWiki holds nothing here and says so rather than guessing.

No form or route is recorded.

No source is stored against this line.

Who oversees it

RNAWiki has not recorded a supervision or regulatory status for this substance.

Quoted from a source

Where this came from

Copied from a source RNAWiki stored, with the source named.

No register row and no identity class settled the question.

No source is stored against this line.

What is in the pack

Not recorded.

Nothing recorded

Where this came from

RNAWiki holds nothing here and says so rather than guessing.

Nothing is recorded about product quality.

No source is stored against this line.

Where it is registered

Not recorded.

Nothing recorded

Where this came from

RNAWiki holds nothing here and says so rather than guessing.

No register entry is recorded.

No source is stored against this line.

Why people stop

Not recorded.

Nothing recorded

Where this came from

RNAWiki holds nothing here and says so rather than guessing.

No record of why people stopped taking it is stored for this substance.

No source is stored against this line.

What it would be like to takeNothing found in the sources checked

What can go wrong

Sorted by where each line came from. A regulator's label and a report somebody sent in are not the same kind of fact.

Nothing found in the sources checked

No harm is recorded against this substance in the sources RNAWiki checked. Finding nothing is not the same as showing there is nothing.

The sources listed were searched and held nothing. That is not the same as nothing existing.

Over a long time. No completed tested study window is recorded, so long-term effects are not established by the registry record.

Groups the studies covered thinly. Which groups were under-represented in the studies has not been recorded for this substance. Pregnancy, breastfeeding, children, older adults, and people with liver or kidney conditions are commonly excluded from trials; nothing here says whether they were.

What is missing or unclearRead from sources, not yet reviewed

Does the exact form matter?

Evidence belongs to the exact thing that was tested. A different salt, a different mixture or a different preparation is a different question.

The form that was studied

Not recorded.

Nothing recorded

Where this came from

RNAWiki holds nothing here and says so rather than guessing.

The exact form studied is not recorded.

No source is stored against this line.

What is sold

Not recorded.

Nothing recorded

Where this came from

RNAWiki holds nothing here and says so rather than guessing.

Nothing further is recorded about which forms are sold.

No source is stored against this line.

What is recorded as being sold

  • 7 products list this as an active ingredient in the United States drug directory. 2 of them contain it and nothing else.

    FDA National Drug Code directory · 52747-621 · read 2026-08-29

  • They are sold as capsule, capsule, liquid filled, injection, liquid and solution/ drops, taken intravenous, ophthalmic and oral.

    FDA National Drug Code directory · 52747-621 · read 2026-08-29

  • The regulator's established pharmacologic class for it is copper absorption inhibitor [epc] and decreased copper ion absorption [pe].

    FDA National Drug Code directory · 52747-621 · read 2026-08-29

  • 6 published labels name it as an active ingredient. 1 of them describe this substance alone, which is where its own label text on this page comes from.

    US prescribing information · b9cf2dab-6ec8-e099-464a-af46a3601971 · read 2026-08-29

  • Those labels are classed as human otc drug and human prescription drug.

    US prescribing information · b9cf2dab-6ec8-e099-464a-af46a3601971 · read 2026-08-29

  • Zinc Sulfate is intravenous at 3 DOSAGE FORMS AND STRENGTHS Zinc Sulfate Injection, USP: 10 mg/10 mL (1 mg/mL) of zinc as a clear, colorless solution in a 10 mL Pharmacy Bulk Package vial. 25 mg/5 mL (5 mg/mL) of zinc as a clear, colorless solution i…, recorded as fda label in effect 2025-01-16 in the United States.

    US prescribing information · b9cf2dab-6ec8-e099-464a-af46a3601971 · read 2026-08-30

Evidence carries across two names for one substance. It does not carry across a salt, a mirror form or a mixture.

What it would be like to takeRead from sources, not yet reviewed

What you could measure

This one is decided with a clinician, so this section holds questions to ask rather than a plan to run.

RNAWiki could not confidently classify this substance, so no self-experiment plan is offered.

Questions worth asking

  • Which of the trials of Zinc Sulfate Anhydrous studied people like me?
  • What was measured, and for how long?
  • Was the result a laboratory value or a health outcome?
  • What would we watch for, and when would we stop?

Tracking can show whether something changed for you. It cannot show what caused it.

RNAWiki records evidence. It does not say whether this substance is right for you.

What is missing or unclearRead from sources, not yet reviewed

What nobody knows yet

Open questions, each with why it is open and what would close it.

Missing populations

Which groups were under-represented in the studies has not been recorded.

Why it matters. Recorded by the evidence model as a gap on this record.

What would answer it

A study that measures it, and a reviewer to sign it off.

Last checked 2026-09-04. Searched: The sources listed in the receipts at the foot of this page.

Missing long-term data

No completed tested study window is recorded.

Why it matters. Recorded by the evidence model as a gap on this record.

What would answer it

A study that measures it, and a reviewer to sign it off.

Last checked 2026-09-04. Searched: The sources listed in the receipts at the foot of this page.

No reviewed conclusion

RNAWiki has not yet published a reviewed conclusion for this use.

Why it matters. Recorded by the evidence model as a gap on this record.

What would answer it

A study that measures it, and a reviewer to sign it off.

Last checked 2026-09-04. Searched: The sources listed in the receipts at the foot of this page.

Missing interaction studies

No interaction was found in the registers checked. Not finding one is not the same as showing there is none.

Why it matters. Recorded by the evidence model as a gap on this record.

What would answer it

A study that measures it, and a reviewer to sign it off.

Last checked 2026-09-04. Searched: The sources listed in the receipts at the foot of this page.

Formulation uncertainty

Several salts, forms or products of Zinc Sulfate Anhydrous are recorded. Results from one form may not transfer to another.

Why it matters. Recorded by the evidence model as a gap on this record.

What would answer it

A study that measures it, and a reviewer to sign it off.

Last checked 2026-09-04. Searched: The sources listed in the receipts at the foot of this page.

Mechanism not reviewed

No reviewed mechanism story exists for this substance.

Why it matters. Recorded by the evidence model as a gap on this record.

What would answer it

A study that measures it, and a reviewer to sign it off.

Last checked 2026-09-04. Searched: The sources listed in the receipts at the foot of this page.

What happened in peopleRead from sources, not yet reviewed

Check any of this yourself

Every line above traced back to the study it came from. This is the technical layer, and the vocabulary changes here.

Where else this substance is registered

FDA substance identifier (UNII)
89DS0H96TB
ChEMBL
CHEMBL1200929
ChEBI
35176
RxNorm concept
39954
DrugBank
DB09322

Checks this page had to pass

  • Passed

    Identity resolved

    no open identity hold

  • Passed

    No unresolved merge across substance families

    no quarantine open

  • Passed

    Every public sentence names a source

    The opening statement carries the origin: Quoted from a stored source.

  • Not passed

    Trial roles classified for highlighted evidence

    No registered study is classified as testing this substance.

  • Passed

    No internal keys in reader text

    enforced by the copy-contract test over the rendered page

  • Not passed

    Safety mode resolved

    No register row and no identity class settled the question.

  • Passed

    Canonical metadata present

    slug and display name present

What is missing or unclearRead from sources, not yet reviewed

How this medicine reached us

Kept near the foot of the page. A historical event moves up only when it changes something about this substance today.

What the approval register records

  • The earliest marketing start date recorded for a listed product is 20090101.

    FDA National Drug Code directory · 52747-621 · read 2026-08-29

What is missing or unclearRead from sources, not yet reviewed

What to learn next

Ordered by what would most change how you read this page, starting with what is easiest to misunderstand.

This order is fixed in code and does not count clicks or time on the page.

What is not here

9 questions this page could not answer

These sections were prepared and left out because there was nothing to put in them. They are listed rather than hidden, so the gaps in this record are visible.

  • What was measured, goal by goal — found nothing in the sources checked.
  • How close this is to real life — found nothing in the sources checked.
  • The path through the body — found nothing in the sources checked.
  • Felt, measured, or meaningful — found nothing in the sources checked.
  • How long anything takes — found nothing in the sources checked.
  • What it may clash with — found nothing in the sources checked.
  • Other ways to the same goal — found nothing in the sources checked.
  • Claims that go past the evidence — found nothing in the sources checked.
  • What changed on this page — found nothing in the sources checked.

The record as stored

The full record, for auditing

Everything above is built from what is below. This layer keeps the technical vocabulary, record identifiers and every stored row, so a reader who wants to check the page can.

Recorded evidence blocks (8)

On the Zinc Sulfate Anhydrous label: indicated for what?

"Zinc sulfate injection is indicated in adult and pediatric patients as a source of zinc for parenteral nutrition when oral or enteral nutrition is not possible, insufficient, or contraindicated. Zinc sulfate injection is a trace element indicated in adult and pediatric patients as a source of zinc for parenteral…": indications and usage on Zinc Sulfate Anhydrous's label. DailyMed label · b9cf2dab-6ec8-e099-464a-af46a3601971 · 2026-08-30

168 registered trials of Zinc Sulfate Anhydrous — at which phases?

Registered studies posting no result
153 of 168

168 registered studies of Zinc Sulfate Anhydrous: 55 na, 45 phase3, 39 phase2, 28 phase4, 10 phase1, 5 na or unstated, 2 early phase1. CLINICALTRIALS_SNAPSHOT · 2026-09-01

0 with a PubMed record

Show the evidence
  • na
    55
  • phase3
    45
  • phase2
    39
  • phase4
    28
  • phase1
    10
  • na or unstated
    5
8 more recorded rows
  • early phase1
    2
  • completed
    117
  • unknown
    25
  • terminated
    10
  • recruiting
    8
  • not yet recruiting
    4
  • withdrawn
    3
  • active not recruiting
    1

recorded 2026-09-01 · last checked 2026-09-04

11 of Zinc Sulfate Anhydrous's trials stopped: safety, accrual/recruitment, other?

safety (1), accrual/recruitment (5) and other (5): Zinc Sulfate Anhydrous's stop wording, clustered. CLINICALTRIALS_SNAPSHOT · 2026-09-01

"Terminated for futility on 11/30/09 based on the recommendation of the DSMB"; 11 of 168 registered studies

Show the evidence

Trial

  • NCT00395161
    terminated; "Terminated for futility on 11/30/09 based on the recommendation of the DSMB"
  • NCT00395226
    terminated; "Difficulty recruiting subjects"
  • NCT01468636
    terminated; "There was no clear benefit but numerous side effects."
  • NCT02130388
    terminated; "Slow Recruitment and funds no longer available."
  • NCT03404310
    terminated; "Lack of recruitment"
  • NCT03532555
    terminated; "Slow enrollment"
5 further recorded trials
  • NCT04321850
    terminated; "Health restrictions due to the COVID-19 pandemic"
  • NCT04528927
    withdrawn; "\- Interest in the use of HCQ is controversial."
  • NCT04621149
    terminated; "Unable to recruit participants due to decline in COVID-19."
  • NCT05000762
    withdrawn; "Sponsor no longer has support available."
  • NCT05894109
    withdrawn; "Per the PI, the project is not IRB approved yet and will likely not be completed."

recorded 2026-09-01 · last checked 2026-09-04

Human studies of Zinc Sulfate Anhydrous used Zinc acetate (20mg/d) — over how long?

Human studies of Zinc Sulfate Anhydrous used "Zinc acetate (20mg/d)". ClinicalTrials.gov · 2026-09-01

13 recorded entries; human; tablet; also "Zinc sulphate (20 mg)", "Zinc (12.5 mg/day)", "Zinc sulphate 20 mg"

Show the evidence

human

  • NCT00104494
    Zinc acetate (20mg/d)
  • NCT00142285
    Zinc sulphate (20 mg)
  • NCT00228254
    Zinc (12.5 mg/day)
  • NCT00355043
    Zinc sulphate 20 mg
  • NCT02072746
    Zinc sulfate 220 mg
  • NCT03005496
    Zinc Picolinate 50 mg
7 more recorded rows
  • human NCT03135522
    Zinc Acetate 50 Mg Oral Capsule
  • human NCT03824925
    Zinc Sulfate 220 MG
  • human NCT04321850
    Zinc Sulfate 50 Mg Tab
  • human NCT04899843
    tablet; Zinc sulphate tablet 20 mg
  • human NCT05178953
    Zinc Sulfate 220 mg Capsules
  • human NCT05190562
    Zinc Sulfate 110 MG (Zinc 25 MG) Oral Tablet
  • human NCT05894109
    zinc citrate 50 mg

recorded 2026-09-01 · last checked 2026-09-04

Which running trial of Zinc Sulfate Anhydrous could settle inflammatory markers?

NCT07275827 measures Serum interleukin-6 (IL-6) level: will be assessed by ELISA, reading out 2026-10.

1 open trial; n 88; "Comparative Study Evaluating Safety and Effectiveness of ( Proton Pump Inhibitor Versus Vonoprazan ) Based Triple Therapy With or Without Zinc to Eradicate H. Pylori Infection"

Show the evidence
  • Trial NCT07275827
    "Comparative Study Evaluating Safety and Effectiveness of ( Proton Pump Inhibitor Versus Vonoprazan ) Based Triple Therapy With or Without Zinc to Eradicate H. Pylori Infection"; n 88; "Serum interleukin-6 (IL-6) level: will be assessed by ELISA"; 2026-10

Which 98 trials of Zinc Sulfate Anhydrous posted no result?

Posted no result
98 of 98 completed trials
Registrations
NCT00226616, NCT00228254, NCT00198666, NCT00212368, NCT00325247 and NCT00408356, and 92 more
Completion dates
oldest 2002-07; newest 2024-05-31
Show the evidence

Trial

  • NCT00226616
    2002-07
  • NCT00228254
    2004-06
  • NCT00198666
    2004-08
  • NCT00212368
    2005-12
  • NCT00325247
    2006-05
  • NCT00408356
    2006-11
14 further recorded trials
  • NCT00000145
    2006-12
  • NCT00370968
    2006-12
  • NCT00149552
    2007-01
  • NCT00373100
    2007-03
  • NCT00098202
    2007-04
  • NCT00036881
    2007-06
  • NCT00272142
    2007-08
  • NCT00104494
    2007-09
  • NCT00355043
    2007-09
  • NCT00459485
    2007-12
  • NCT01166815
    2008-01
  • NCT00682955
    2008-04
  • NCT00142285
    2008-05
  • NCT00252304
    2008-07

At the median, Zinc Sulfate Anhydrous's trials enrolled 100 people — anything larger?

Median enrolment
100
Largest enrolment
8000
Registered trials counted
165

What do 496 spontaneous reports say about Zinc Sulfate Anhydrous — and not say?

These are reports people sent to a regulator. They do not show the medicine caused the reaction. Nobody counted how many people took the medicine and reported nothing. The same event can be reported more than once, and many reports are incomplete. News coverage, lawsuits and new warnings change how often people report. A count is not a rate and not a risk.

Zinc Sulfate Anhydrous appears in spontaneous reports to regulators. Across the 10 most-reported reaction terms, 496 reaction mentions were counted: gastrooesophageal reflux disease 83; somnolence 76; pneumonia aspiration 74; coma 73. FAERS via Open Targets · CHEMBL1200929 · 2026-06-24

Show the evidence
  • gastrooesophageal reflux disease
    83
  • somnolence
    76
  • pneumonia aspiration
    74
  • coma
    73
  • condition aggravated
    47
  • drug hypersensitivity
    33
4 more recorded rows
  • pruritus
    31
  • treatment failure
    29
  • drug intolerance
    28
  • macular degeneration
    22

recorded 2026-06-24 · last checked 2026-09-04

Where it is registered
Identifiers, relations and other names

The exact record

ChEMBL id
CHEMBL1200929
PubChem CID
24424
CAS number
7733-02-0
RxCUI
1299928
InChIKey
NWONKYPBYAMBJT-UHFFFAOYSA-L
Also called
Zinc Sulfate, Unspecified Form
Also called
ZINC SULFATE, Sulfuric acid, zinc salt (1:1), Zinci sulfas heptahydrate, Zincum sulphuricum, zinc supplement, zinc supplementation, ZINC SULFATE [HSDB], ZINC SULFATE [MI]
Development code
NSC-135806, NSC-32677
Trade name
Pennine, Sootheye, White vitriol, Zincfrin, Zincomed, Zincosol, Zindole, Zing, Zn sulf co, Z span
Salt form
Zinc (as sulfate), Zinci sulfas monohydrate, Zinc sulfate (1:1) heptahydrate, Zinc sulfate (1:1) monohydrate, Zinc sulfate component of multrys, Zinc sulfate component of tralement, Zinc sulfate hydrate, Zinc sulfate, unspecified, Zinc sulfate, unspecified hydrate, Zinc sulphate, Zinc sulphate (1:1) heptahydrate, Zinc sulphate (1:1) monohydrate
Component
Zinc Sulfate, Unspecified Form
Sources (5)

Sources

ChEMBL 37 — CC BY-SA 3.0 Unported · ChEMBL ATC CC BY-SA · ClinicalTrials.gov — US Government work · Open Targets 26.06 — CC0 · openFDA / DailyMed — US Government work

How these records are assembled · Which registers were checked

Index-quality checks
  • identity passed: no open identity hold
  • required summary fields resolved: 3 required field(s) not terminal: Best-supported result, Biggest unanswered question, Human evidence
  • public claims reviewed: 0 reviewed claim(s); drafts are never rendered
  • source coverage passed: 5 source rows
  • no critical contamination: no quarantine open
  • canonical metadata passed: slug and display name present
  • no raw internal fields: enforced by the copy-contract test over the rendered page

This is a record of evidence. It is not medical advice, and it does not say this substance suits you. Nothing here says any substance on RNAWiki is appropriate for a child.