Streptococcus Pneumoniae Type 7f Capsular Polysaccharide Diphtheria Crm197 Protein Conjugate Antigen
- Vaccine
- Still being tested
- Identity checked
- Sources last checked 2026-09-04
This page shows what was measured, who it was measured in, and what that does not settle.
RNAWiki holds very little about this substance. The page shows what there is.
What Streptococcus Pneumoniae Type 7f Capsular Polysaccharide Diphtheria Crm197 Protein Conjugate Antigen does in the body
RNAWiki has not recorded what this substance changes in the body.
What happened in people
RNAWiki has not yet published a reviewed conclusion for this use.
A fixed RNAWiki sentence
Where this came from
Wording RNAWiki always uses, not a finding about this substance.
No reviewed claim names a result for any goal on this record.
No source is stored against this line.
The limit that matters most
Not recorded.
- Where it acts
- Not recorded.
- Kind of result
- No result is published, so no kind of result applies yet
- Supervision
- Professional supervision is normally required. It is a prescription or clinician-administered medicine where it is approved.
What the registries record it as
The substance registry classes this as structurallydiverse.
FDA substance registry · 0K0S2P98ZJ · read 2026-08-29
It is recorded as coming from STREPTOCOCCUS PNEUMONIAE SEROTYPE 7F WHOLE. The part recorded is capsule.
FDA substance registry · 0K0S2P98ZJ · read 2026-08-29
Where each sentence above came from
No plain explanation of what this changes is stored.
No recorded use is stored in reader language.
No statement of the main limit is recorded.
The four opening statements run to 26 words.
Words this page uses
Four words worth knowing first
Chosen from what this page shows, with each one explained before the word it depends on.
Stand-in result
A stand-in result is a number measured because the real result takes too long.
A picture of it, and where the picture fails
It is like judging a journey by the speedometer rather than by arriving.
Where that stops being true. Speed does predict arrival. Many stand-in results do not predict the real one.
What people get wrong. A stand-in result is often reported as the result itself.
A surrogate endpoint substituted for a clinical endpoint, valid only where the substitution has been shown to hold.
Enzyme
An enzyme is a protein that speeds up one chemical change.
A picture of it, and where the picture fails
An enzyme is like a machine on a production line doing one cut.
Where that stops being true. A machine is switched on and off by a person. Enzymes are controlled by the cell.
What people get wrong. Enzymes are thought to be used up. They are not; they work again and again.
A catalytic protein that lowers the activation energy of a specific reaction.
Receptor
A receptor is a part of a cell that a signal fits into.
A picture of it, and where the picture fails
A receptor is like a lock waiting for one key.
Where that stops being true. A lock either opens or does not. A receptor can be half-triggered, or worn out.
What people get wrong. Fitting a receptor is read as causing a benefit. It causes a step, and nothing more.
A protein that binds a specific ligand and converts that binding into a cellular response.
Pathway
A pathway is a chain of steps inside a cell, each one setting off the next.
A picture of it, and where the picture fails
A pathway is like a row of dominoes.
Where that stops being true. Dominoes fall one way. Pathways loop back and can switch themselves off.
What people get wrong. Changing one step is read as changing the outcome. Other steps often absorb it.
An ordered series of molecular interactions producing a defined cellular change.
What happened in peopleRead from sources, not yet reviewed
How close this is to real life
The top step is something a person would feel or care about. The bottom is a guess from software. Filled steps are where evidence exists for this substance.
- Living longer, or avoiding a major event No evidence recorded. Death, a heart attack, a stroke, a hospital stay.No registered study measures this.
- What a body can do day to day No evidence recorded. Walking, dressing, breathing, recovering.No registered study measures this.
- Measured performance No evidence recorded. How much was lifted, how far was run, how fast.No registered study measures this.
- Symptoms and quality of life No evidence recorded. Pain, tiredness, mood, sleep, as the person rated it.No registered study measures this.
- A number that stands in for health Evidence recorded. Cholesterol, blood sugar, bone density. A stand-in, not the thing itself.12 registered measures of this kind.
- A step measured inside a person Evidence recorded. Something measured in human tissue or human cells.A human record sits on the stored organism ladder.
- Animals Evidence recorded. Mice, rats, dogs. Useful for ideas, not proof about people.Stored records in Mouse. A result in animals says what to test next. It does not say what happens in people.
- Cells in a dish No evidence recorded. Cells or chemistry on a bench, far from a whole body.No cell or bench record is stored.
- A guess from software No evidence recorded. Nobody measured it. RNAWiki never publishes one as a finding.RNAWiki stores no prediction for this record. Software can suggest a link. RNAWiki does not publish one as a finding.
Higher on these steps means closer to something a person would feel. It does not mean better done.
What it would be like to takeRead from sources, not yet reviewed
Felt, measured, or meaningful
Three different things that get called the same word. Registered studies measured all three, and mixing them is how a blood test becomes a health claim.
Felt
Things a person could notice without a test.
No registered study measured anything of this kind.
Measured
Things only a test, a scale or a device shows.
- anti polyribosylribitol phosphate antibody concentrations
- anti streptococcus pneumoniae antibody concentrations
- igg geometric mean concentrations for postvaccination 3
- geometric mean concentration of antibodies to tetanus toxin
- antibody concentration 0 2 / for pneumococcal serotypes
- anti measles virus antibody concentrations
- anti mumps virus antibody concentrations
- anti rubella virus antibody concentrations
- anti mumps virus antibody concentration
- anti rubella virus antibody concentration
and 2 more.
Meaningful
Things that change how a life goes, not only a number.
No registered study measured anything of this kind.
A registered study says what someone planned to measure. It does not say what they found. A number moving is not the same as a life going better. The two are shown apart here.
Felt, but not shown to help. A person notices a change. No study showed it leads anywhere good.
Measured, but not felt. A number moves. The person notices nothing. Both can be true.
Measured, but not shown to matter. A number moves in the good direction. Nobody showed that lives went better.
Matters, but takes years. The result that counts may take longer than anyone would keep watching.
Names that fit none of the three (28)
- igg gmcs for postvaccination 4
- an adverse event
- an injection site ae
- systemic ae
- serious adverse event
- who discontinued the study due to an ae
- t cell immunity augmentation
- responding to polyribosylribitol phosphate antigen
- responding to hepatitis b surface antigen
- responding to diphtheria toxin
- responding to tetanus toxin
- responding to pertussis toxin
- responding to pertussis filamentous hemagglutinin
- responding to pertussis pertactin
- responding to pertussis fimbriae
- responding to poliovirus type 1
- responding to poliovirus type 2
- geometric mean titer for antibodies to poliovirus type 1
- geometric mean titer for antibodies to poliovirus type 2
- response conversion rate
These are harms, study-process measures, or names the rules did not recognise. They are shown rather than dropped.
What is missing or unclearRead from sources, not yet reviewed
Were people like you studied?
RNAWiki cannot tell whether a study fits you. It can show who was in it, and where the result stops carrying.
Who was studied
No description of who was studied is recorded.
Who is missing from the studies
- Which groups were under-represented in the studies has not been recorded for this substance. Pregnancy, breastfeeding, children, older adults, and people with liver or kidney conditions are commonly excluded from trials; nothing here says whether they were.
Where the result stopped carrying
- This is a scope explorer, not a diagnosis engine.
- It shows who was studied so you can see whether people similar to you were included.
RNAWiki cannot tell whether a study fits you. It can show who was in it.
What it would be like to takeRead from sources, not yet reviewed
Why it might seem to do nothing
A real effect and a noticed effect are different things. These are the recorded reasons the two come apart.
The studies measured something else entirely.
On this record: Some registered studies measured things that match no goal on this page.
The people in the studies were not much like the reader.
On this record: Which groups were under-represented in the studies has not been recorded for this substance. Pregnancy, breastfeeding, children, older adults, and people with liver or kidney conditions are commonly excluded from trials; nothing here says whether they were.
Small early studies often do not hold up.
On this record: RNAWiki has not yet published a reviewed conclusion for this use.
Other reasons RNAWiki checked and found nothing for (10)
- A different form was studied
- The studied form is not the form on the shelf. Nothing in this record points to this reason.
- There was nothing to correct
- Where a level is already normal, topping it up may change nothing. Nothing in this record points to this reason.
- Something else had to happen too
- In the studies it was paired with training, a diet or another treatment. Nothing in this record points to this reason.
- The change is too small to feel
- A real change can still sit below what a person notices. Nothing in this record points to this reason.
- Day-to-day swing hides it
- Sleep, food, stress and time of day move most numbers more than this would. Nothing in this record points to this reason.
- Not enough time yet
- The studies ran longer than the person has waited. Nothing in this record points to this reason.
- It was not taken as studied
- Missed days change the result, and studies count them. Nothing in this record points to this reason.
- Something else changed at the same time
- Two changes at once cannot be told apart afterwards. Nothing in this record points to this reason.
- The product may not be what it says
- Contents of a sold product are not always what the label states. Nothing in this record points to this reason.
- No recorded reason
- RNAWiki has nothing stored that would explain it. Nothing in this record points to this reason.
None of these is a reason to take more. Taking more is not a step this page ever suggests.
What it would be like to takeRead from sources, not yet reviewed
What taking it involves
The recorded facts about getting hold of it and using it. Nothing here is a suggestion about what you should do.
How it is supplied
Still being tested
Quoted from a source
Where this came from
Copied from a source RNAWiki stored, with the source named.
Read from the recorded approval status.
No source is stored against this line.
Form and route
Not recorded.
Nothing recorded
Where this came from
RNAWiki holds nothing here and says so rather than guessing.
No form or route is recorded.
No source is stored against this line.
Who oversees it
Professional supervision is normally required. It is a prescription or clinician-administered medicine where it is approved.
Quoted from a source
Where this came from
Copied from a source RNAWiki stored, with the source named.
The identity record classes it as investigational; no register records an approval.
No source is stored against this line.
What is in the pack
Not recorded.
Nothing recorded
Where this came from
RNAWiki holds nothing here and says so rather than guessing.
Nothing is recorded about product quality.
No source is stored against this line.
Where it is registered
Regulatory records are listed in the technical disclosure at the foot of this page.
Counted from records
Where this came from
A count of rows RNAWiki holds. It describes our records, not your body.
Register entries are stored per jurisdiction and shown with their dates.
No source is stored against this line.
Why people stop
Not recorded.
Nothing recorded
Where this came from
RNAWiki holds nothing here and says so rather than guessing.
No record of why people stopped taking it is stored for this substance.
No source is stored against this line.
What it would be like to takeNothing found in the sources checked
What can go wrong
Sorted by where each line came from. A regulator's label and a report somebody sent in are not the same kind of fact.
Nothing found in the sources checked
No harm is recorded against this substance in the sources RNAWiki checked. Finding nothing is not the same as showing there is nothing.
The sources listed were searched and held nothing. That is not the same as nothing existing.
Over a long time. No completed tested study window is recorded, so long-term effects are not established by the registry record.
Groups the studies covered thinly. Which groups were under-represented in the studies has not been recorded for this substance. Pregnancy, breastfeeding, children, older adults, and people with liver or kidney conditions are commonly excluded from trials; nothing here says whether they were.
What is missing or unclearRead from sources, not yet reviewed
Does the exact form matter?
Evidence belongs to the exact thing that was tested. A different salt, a different mixture or a different preparation is a different question.
The form that was studied
Not recorded.
Nothing recorded
Where this came from
RNAWiki holds nothing here and says so rather than guessing.
The exact form studied is not recorded.
No source is stored against this line.
What is sold
Not recorded.
Nothing recorded
Where this came from
RNAWiki holds nothing here and says so rather than guessing.
Nothing further is recorded about which forms are sold.
No source is stored against this line.
What is recorded as being sold
7 products list this as an active ingredient in the United States drug directory. None of them contains it on its own, so nothing on this page can separate it from what it is combined with.
FDA National Drug Code directory · 0006-4329 · read 2026-08-29
They are sold as injection, solution and injection, suspension, taken intramuscular.
FDA National Drug Code directory · 0006-4329 · read 2026-08-29
Evidence carries across two names for one substance. It does not carry across a salt, a mirror form or a mixture.
What it would be like to takeRead from sources, not yet reviewed
What you could measure
This one is decided with a clinician, so this section holds questions to ask rather than a plan to run.
Self-experiment planning is not offered for a prescription or clinician-supervised medicine, investigational agent. The questions below are for a clinician or pharmacist.
Questions worth asking
- Which of the trials of Streptococcus Pneumoniae Type 7f Capsular Polysaccharide Diphtheria Crm197 Protein Conjugate Antigen studied people like me?
- What was measured, and for how long?
- Was the result a laboratory value or a health outcome?
- What would we watch for, and when would we stop?
Tracking can show whether something changed for you. It cannot show what caused it.
RNAWiki records evidence. It does not say whether this substance is right for you.
What is missing or unclearRead from sources, not yet reviewed
What nobody knows yet
Open questions, each with why it is open and what would close it.
How much did people take in the studies?
The sources RNAWiki checked hold nothing for this field.
Why it matters. A result belongs to an amount. Without the amount the result floats free.
What would answer it
A stored source that records it, and a reviewer to sign it off.
Last checked 2026-09-04. Searched: The sources listed in the receipts at the foot of this page.
How fast does the body clear it?
The sources RNAWiki checked hold nothing for this field.
Why it matters. Without this, nothing on this page can say how long anything lasts.
What would answer it
A stored source that records it, and a reviewer to sign it off.
Last checked 2026-09-04. Searched: The sources listed in the receipts at the foot of this page.
Missing populations
Which groups were under-represented in the studies has not been recorded.
Why it matters. Recorded by the evidence model as a gap on this record.
What would answer it
A study that measures it, and a reviewer to sign it off.
Last checked 2026-09-04. Searched: The sources listed in the receipts at the foot of this page.
Missing long-term data
No completed tested study window is recorded.
Why it matters. Recorded by the evidence model as a gap on this record.
What would answer it
A study that measures it, and a reviewer to sign it off.
Last checked 2026-09-04. Searched: The sources listed in the receipts at the foot of this page.
No reviewed conclusion
RNAWiki has not yet published a reviewed conclusion for this use.
Why it matters. Recorded by the evidence model as a gap on this record.
What would answer it
A study that measures it, and a reviewer to sign it off.
Last checked 2026-09-04. Searched: The sources listed in the receipts at the foot of this page.
Missing interaction studies
No interaction was found in the registers checked. Not finding one is not the same as showing there is none.
Why it matters. Recorded by the evidence model as a gap on this record.
What would answer it
A study that measures it, and a reviewer to sign it off.
Last checked 2026-09-04. Searched: The sources listed in the receipts at the foot of this page.
Formulation uncertainty
Several salts, forms or products of Streptococcus Pneumoniae Type 7f Capsular Polysaccharide Diphtheria Crm197 Protein Conjugate Antigen are recorded. Results from one form may not transfer to another.
Why it matters. Recorded by the evidence model as a gap on this record.
What would answer it
A study that measures it, and a reviewer to sign it off.
Last checked 2026-09-04. Searched: The sources listed in the receipts at the foot of this page.
Mechanism not reviewed
No reviewed mechanism story exists for this substance.
Why it matters. Recorded by the evidence model as a gap on this record.
What would answer it
A study that measures it, and a reviewer to sign it off.
Last checked 2026-09-04. Searched: The sources listed in the receipts at the foot of this page.
What happened in peopleRead from sources, not yet reviewed
Check any of this yourself
Every line above traced back to the study it came from. This is the technical layer, and the vocabulary changes here.
Where else this substance is registered
- FDA substance identifier (UNII)
- 0K0S2P98ZJ
- RxNorm concept
- 901636
- DrugBank
- DB10297
Checks this page had to pass
Passed
Identity resolved
no open identity hold
Passed
No unresolved merge across substance families
no quarantine open
Not passed
Every public sentence names a source
The opening statement carries no source: the record holds neither an explanation nor a recorded use.
Not passed
Trial roles classified for highlighted evidence
No registered study is classified as testing this substance.
Passed
No internal keys in reader text
enforced by the copy-contract test over the rendered page
Passed
Safety mode resolved
The identity record classes it as investigational; no register records an approval.
Passed
Canonical metadata present
slug and display name present
What is missing or unclearRead from sources, not yet reviewed
How this medicine reached us
Kept near the foot of the page. A historical event moves up only when it changes something about this substance today.
What the approval register records
The earliest marketing start date recorded for a listed product is 20100312.
FDA National Drug Code directory · 0006-4329 · read 2026-08-29
What is missing or unclearRead from sources, not yet reviewed
What to learn next
Ordered by what would most change how you read this page, starting with what is easiest to misunderstand.
- Were people like me actually studied?
- How close is this evidence to something I would notice?
- What does nobody know about this yet?
- What is a stand-in result?
This order is fixed in code and does not count clicks or time on the page.
What is not here
8 questions this page could not answer
These sections were prepared and left out because there was nothing to put in them. They are listed rather than hidden, so the gaps in this record are visible.
- What was measured, goal by goal — found nothing in the sources checked.
- What happened in people — found nothing in the sources checked.
- The path through the body — found nothing in the sources checked.
- How long anything takes — found nothing in the sources checked.
- What it may clash with — found nothing in the sources checked.
- Other ways to the same goal — found nothing in the sources checked.
- Claims that go past the evidence — found nothing in the sources checked.
- What changed on this page — found nothing in the sources checked.
The record as stored
The full record, for auditing
Everything above is built from what is below. This layer keeps the technical vocabulary, record identifiers and every stored row, so a reader who wants to check the page can.
Recorded evidence blocks (8)
What did Streptococcus Pneumoniae Type 7f Capsular Polysaccharide Diphtheria Crm197 Protein Conjugate Antigen's largest trial (1000000 people) and its longest (14 years) measure?
1000000 people in Streptococcus Pneumoniae Type 7f Capsular Polysaccharide Diphtheria Crm197 Protein Conjugate Antigen's largest registered study, 14 years in its longest registered window, measuring Number of Subjects With Anti-polyribosylribitol Phosphate (Anti-PRP) Antibody Concentrations Greater Than or Equal to (≥) 0.15 Microgram Per Milliliter (µg/mL) and ≥ 1.0 µg/mL. ClinicalTrials.gov · 2026-09-01
53 phase3, 34 phase2, 19 phase1, 10 phase4, 3 early phase1, 1 na or unstated; NCT05170399; 2036-11-15. Last human test completed 2026, NCT06182124.
These counts include studies where Streptococcus Pneumoniae Type 7f Capsular Polysaccharide Diphtheria Crm197 Protein Conjugate Antigen was a comparison treatment, a background treatment or an exposure in an observational study, and the longest window may be a planned end date. Trial roles have not yet been classified for this record.
Show the evidence
- phase353
- phase234
- phase119
- phase410
- early phase13
- na or unstated1
1 more recorded row
- Last recorded human test NCT061821242026-05-12
recorded 2026-09-01 · last checked 2026-09-04
From mouse to human: where has Streptococcus Pneumoniae Type 7f Capsular Polysaccharide Diphtheria Crm197 Protein Conjugate Antigen shown biomarker?
mouse: mechanism-only and human: biomarker (109): the rungs where Streptococcus Pneumoniae Type 7f Capsular Polysaccharide Diphtheria Crm197 Protein Conjugate Antigen has a recorded finding. Europe PMC and ClinicalTrials.gov · organism ladder · 2026-09-01
Number of Subjects With Anti-polyribosylribitol Phosphate (Anti-PRP) Antibody Concentrations Greater Than or Equal to (≥) 0.15 Microgram Per Milliliter (µg/mL)… — the recorded outcome words.
Show the evidence
- mousemechanism-only
- human NCT01000974biomarker; Number of Subjects With Anti-polyribosylribitol Phosphate (Anti-PRP) Antibody Concentrations Greater Than or Equal to (≥) 0.15 Microgram Per Milliliter (µg/mL) and ≥ 1.0 µg/mL; 109
recorded 2026-09-01 · last checked 2026-09-04
5 of Streptococcus Pneumoniae Type 7f Capsular Polysaccharide Diphtheria Crm197 Protein Conjugate Antigen's trials stopped: safety, accrual/recruitment, sponsor decision unspecified, other?
safety (1), accrual/recruitment (2), sponsor decision unspecified (1) and other (1): Streptococcus Pneumoniae Type 7f Capsular Polysaccharide Diphtheria Crm197 Protein Conjugate Antigen's stop wording, clustered. ClinicalTrials.gov · 2026-09-01
"Low accrual and loss of funding."; 5 of 109 registered studies
Show the evidence
Trial
- NCT01282216terminated; "Low accrual and loss of funding."
- NCT02309515terminated; "Slow Accrual"
- NCT02716805terminated; "FDA placed on partial hold due to additional data"
- NCT03550313terminated; "Study vaccinations and blood draws were halted due to adequacy of a smaller dataset and study feasibility issues. It was not based on any safety concerns."
- NCT06397768terminated; "Sponsor decision"
recorded 2026-09-01 · last checked 2026-09-04
Could one person measure Streptococcus Pneumoniae Type 7f Capsular Polysaccharide Diphtheria Crm197 Protein Conjugate Antigen's effect on anti polyribosylribitol phosphate antibody concentrations?
Anti polyribosylribitol phosphate antibody concentrations: measured in Streptococcus Pneumoniae Type 7f Capsular Polysaccharide Diphtheria Crm197 Protein Conjugate Antigen's trials.
Interpretation anti polyribosylribitol phosphate antibody concentrations is the recorded endpoint.
Show the evidence
biomarkers
- anti polyribosylribitol phosphate antibody concentrations; 2026-09-01
- anti streptococcus pneumoniae antibody concentrations; 2026-09-01
- igg geometric mean concentrations for postvaccination 3; 2026-09-01
- igg gmcs for postvaccination 4; 2026-09-01
- an adverse event; 2026-09-01
- an injection site ae; 2026-09-01
14 more recorded rows
- biomarkerssystemic ae; 2026-09-01
- biomarkersserious adverse event; 2026-09-01
- biomarkerswho discontinued the study due to an ae; 2026-09-01
- biomarkerst cell immunity augmentation; 2026-09-01
- biomarkersresponding to polyribosylribitol phosphate antigen; 2026-09-01
- biomarkersresponding to hepatitis b surface antigen; 2026-09-01
- biomarkersresponding to diphtheria toxin; 2026-09-01
- biomarkersresponding to tetanus toxin; 2026-09-01
- biomarkersresponding to pertussis toxin; 2026-09-01
- biomarkersresponding to pertussis filamentous hemagglutinin; 2026-09-01
- biomarkersresponding to pertussis pertactin; 2026-09-01
- biomarkersresponding to pertussis fimbriae; 2026-09-01
- biomarkersresponding to poliovirus type 1; 2026-09-01
- biomarkersresponding to poliovirus type 2; 2026-09-01
- human trials at or under307
- Not recorded for this substancea recorded half-life
- smallest human trial6; NCT02716805; PHASE1; the smallest recorded human enrolment at or below 30; the registry states no direction of its result; TERMINATED
Which of a serious adverse event, a vaccine related serious adverse event and adult experiencing 1 adverse event did Streptococcus Pneumoniae Type 7f Capsular Polysaccharide Diphtheria Crm197 Protein Conjugate Antigen's trials measure?
a serious adverse event, a vaccine related serious adverse event and adult experiencing 1 adverse event lead 40 outcome terms across Streptococcus Pneumoniae Type 7f Capsular Polysaccharide Diphtheria Crm197 Protein Conjugate Antigen's trials. ClinicalTrials.gov · 2026-09-01
igg gmcs for postvaccination 4, an adverse event, an injection site ae, systemic ae, serious adverse event and who discontinued the study due to an ae follow.
Show the evidence
- anti polyribosylribitol phosphate antibody concentrations1
- anti streptococcus pneumoniae antibody concentrations1
- igg geometric mean concentrations for postvaccination 31
- igg gmcs for postvaccination 41
- an adverse event1
- an injection site ae1
14 more recorded rows
- systemic ae1
- serious adverse event1
- who discontinued the study due to an ae1
- t cell immunity augmentation1
- responding to polyribosylribitol phosphate antigen1
- responding to hepatitis b surface antigen1
- responding to diphtheria toxin1
- responding to tetanus toxin1
- responding to pertussis toxin1
- responding to pertussis filamentous hemagglutinin1
- responding to pertussis pertactin1
- responding to pertussis fimbriae1
- responding to poliovirus type 11
- responding to poliovirus type 21
recorded 2026-09-01 · last checked 2026-09-04
Which of Streptococcus Pneumoniae Type 7f Capsular Polysaccharide Diphtheria Crm197 Protein Conjugate Antigen's 25 ongoing trials reports first?
25 registered trials of Streptococcus Pneumoniae Type 7f Capsular Polysaccharide Diphtheria Crm197 Protein Conjugate Antigen are open; earliest completion 2026-10-31. ClinicalTrials.gov · 2026-09-01
Determine pneumococcal specific IgG levels in BAL (BronchoAlveolar Lavage) fluid and NPF (Nasopharyngeal Fluid); Incidence of significant toxicity (Pilot study); latest 2036-11-15
Show the evidence
Trial
- NCT03729778"Impact of HIV-1 and Aging on Mucosal Vaccine Responses"; n 100; "Determine pneumococcal specific IgG levels in BAL (BronchoAlveolar Lavage) fluid and NPF (Nasopharyngeal Fluid)"; 2028-01-01
- NCT03942328"Modified Immune Cells (Autologous Dendritic Cells) and a Vaccine (Prevnar) Combined With Immune Checkpoint Inhibition After High-Dose External Beam Radiation Therapy in Treating Patients With Unresectable Liver Cancer"; n 85; "Incidence of significant toxicity (Pilot study)"; 2031-02-28
- NCT04745559"Optimizing Cellular and Humoral Immunity by Vaccinating With PCV13 Before and After CAR-T Therapy"; n 26; "Humoral Response Rate -PCV13 vaccine"; 2027-06
- NCT05170399"Vaccine Responses in Patients With B Cell Malignancies"; n 350; "Serologic response against each administered vaccine following completion of the vaccine series in each study arm"; 2036-11-15
- NCT05183854"Pneumococcal Pneumonia Vaccine Series (PCV20 and PPSV23) in Patients With Chronic Lymphocytic Leukemia Associated Immunodeficiency, PROTECT CLL Trial"; n 61; "Proportion of patients who achieve the protocol defined change in antibody titers"; 2028-06
- NCT05417165"Anti-pneumococcal Vaccine Strategy in Patients With Chronic Lymphocytic Leukemia"; n 80; "Proportion of patients with anti-pneumococcal immunogenicity following early revaccination (1 year)"; 2026-10-31
14 further recorded trials
- NCT06524414"A Study to Learn About How a New Pneumococcal Vaccine Works in Infants"; n 605; "Percentage of participants reporting local reactions within 7 days after each dose"; 2027-05-01
- NCT06647407"Safety and Immunogenicity of an Investigational Pentavalent Meningococcal ABCYW Vaccine Against Meningococcal Disease in Children, Toddlers, and Infants"; n 750; "Number of participants with unsolicited immediate adverse events (AEs)"; 2027-05-17
- NCT06693895"A Study on the Safety of an Investigational Chickenpox Vaccine, When Given to Healthy Children, 12 to 15 Months of Age"; n 750; "Percentage of participants reporting each solicited administration site events"; 2026-11-23
- NCT06731374"Carriage to Assess Protection of New Pneumococcal Vaccines - PCV15"; n 106; "Presence or absence of experimental SPN3 colonisation acquisition"; 2026-12
- NCT06740630"A Study on the Immune Response and Safety of an Investigational Chickenpox Vaccine When Given to Healthy Children 12 to 15 Months of Age"; n 1840; "Percentage of participants with seroresponse to Varicella Zoster Virus (VZV) anti-glycoprotein E (gE) Immunoglobulin (IgG) for the 3 lots of VNS vaccine groups"; 2027-05-17
- NCT06806137"A Study on the Immune Response and Safety of the Second Dose of an Investigational Chickenpox Vaccine When Given to Healthy Children 3 Months After a First Dose at 12 to 15 Months of Age"; n 600; "Percentage of participants with seroresponse to Varicella Zoster Virus (VZV) anti- glycoprotein E (gE) IgG for 2 doses of VNS vaccine compared to 2 doses of VV"; 2027-05-03
- NCT06855160"A Study on the Immune Response and Safety of an Investigational Chickenpox Vaccine and a Marketed Measles, Mumps and Rubella Vaccine When Administered as Intramuscular Injection to Healthy Children 12 to 15 Months of Age"; n 911; "Percentage of participants with seroresponse to Varicella Zoster Virus (VZV) anti- glycoprotein E (gE) Immunoglobulin (IgG)"; 2027-02-02
- NCT06975878"Study of a 21-valent Pneumococcal Conjugate Vaccine in Healthy Infants From Approximately 2 Months of Age"; n 1092; "Seroresponse rate for PCV21 and 15vPCV serotypes"; 2027-08-25
- NCT07017777"A Study to Evaluate the Immunogenicity and Safety of 13-valent Pneumococcal Conjugate Vaccine (PCV13i) in Healthy Infants Aged 2 Months (Minimum 6 Weeks)"; n 600; "Proportion of participants achieving serotype-specific IgG antibody concentrations ≥ 0.35 µg/mL"; 2028-05-15
- NCT07160244"BEATRIX: A Study to Learn About a Group B Streptococcus Vaccine in Healthy Pregnant Women and Their Babies"; n 6000; "The proportion of maternal participants reporting prespecified local reactions within 7 days following study intervention"; 2029-03-02
- NCT07168915"A Study of V118E in Healthy Participants (V118E-003)"; n 126; "Number of Participants With Solicited Injection-Site Adverse Events (AEs)"; 2027-07-06
- NCT07247188"Study of a Single Dose of a 21-valent Pneumococcal Conjugate Vaccine in Children and Adolescents With Sickle Cell Disease"; n 100; "Number of participants reporting immediate adverse events (AEs)"; 2027-01-07
- NCT07284654"Safety, Tolerability, and Immunogenicity of VAX-31 in Adults ≥50 Years With Immunobridging to Adults 18-49"; n 4049; "Serotype-specific OPA geometric mean titers (GMT) in 50 year olds and above"; 2027-01
- NCT07348692"Lot-to-lot Consistency Study of a 21-valent Pneumococcal Conjugate Vaccine in Healthy Infants From 2 Months of Age"; n 2195; "For all participants: Serotype specific Immunoglobulin g (IgG) Geometric Mean Concentration (GMC)"; 2028-05-29
recorded 2026-09-01 · last checked 2026-09-04
Which 11 trials of Streptococcus Pneumoniae Type 7f Capsular Polysaccharide Diphtheria Crm197 Protein Conjugate Antigen posted no result?
- Posted no result
- 11 of 11 completed trials
- Registrations
- NCT02141009, NCT02072525, NCT02851056, NCT03642847, NCT06698198 and NCT02494999, and 5 more
- Completion dates
- oldest 2014-12; newest 2023-03-31
Show the evidence
Trial
- NCT021410092014-12
- NCT020725252015-06-02
- NCT028510562018-08-09
- NCT036428472019-03-29
- NCT066981982019-09-30
- NCT024949992019-10
5 further recorded trials
- NCT030394912020-03-30
- NCT023700692020-08
- NCT019535102021-11-08
- NCT045255992022-04-06
- NCT033845892023-03-31
At the median, Streptococcus Pneumoniae Type 7f Capsular Polysaccharide Diphtheria Crm197 Protein Conjugate Antigen's trials enrolled 600 people — anything larger?
- Median enrolment
- 600
- Largest enrolment
- 1000000
- Registered trials counted
- 109
Where it is registered
Identifiers, relations and other names
The exact record
- UNII
- 0K0S2P98ZJ
- RxCUI
- 901636
- Trade name
- Vaxneuvance, Capvaxive, Prevnar 13, Prevnar 20, Vaxneuvance / Capvaxive / Prevnar 13 / Prevnar 20, PREVNAR-13 COMPONENT STREPTOCOCCUS PNEUMONIAE TYPE 7F CAPSULAR POLYSACCHARIDE DIPHTHERIA CRM197 PROTEIN CONJUGATE ANTIGEN, VAXNEUVANCE COMPONENT STREPTOCOCCUS PNEUMONIAE TYPE 7F CAPSULAR POLYSACCHARIDE DIPHTHERIA CRM197 PROTEIN CONJUGATE ANTIGEN
- Also called
- PNEUMOCOCCAL POLYSACCHARIDE SEROTYPE 7F-CRM197 GLYCOCONJUGATE, PREVNAR-20 COMPONENT STREPTOCOCCUS PNEUMONIAE TYPE 7F CAPSULAR POLYSACCHARIDE DIPHTHERIA CRM197 PROTEIN CONJUGATE ANTIGEN, STREPTOCOCCUS PNEUMONIAE SEROTYPE 7F CAPSULAR ANTIGEN DIPHTHERIA CRM197 PROTEIN CONJUGATE VACCINE
Sources (3)
Sources
- ClinicalTrials.gov ClinicalTrials.gov API v2 snapshot 2026-09-01T09:00:05 ·
- this record's own fields 2,3,5 ·
- Europe PMC and ClinicalTrials.gov organism ladder ·
ClinicalTrials.gov — US Government work · Europe PMC — metadata only, under the recorded legal gate · derived from this page's own recorded fields; no external licence
How these records are assembled · Which registers were checked
Index-quality checks
- identity passed: no open identity hold
- required summary fields resolved: 3 required field(s) not terminal: Best-supported result, Biggest unanswered question, Human evidence
- public claims reviewed: 0 reviewed claim(s); drafts are never rendered
- source coverage passed: 3 source rows
- no critical contamination: no quarantine open
- canonical metadata passed: slug and display name present
- no raw internal fields: enforced by the copy-contract test over the rendered page
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