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Aqua

  • Prescription medicine
  • Prescription only
  • Identity checked
  • Sources last checked 2026-09-04

This page shows what was measured, who it was measured in, and what that does not settle.

What Aqua does in the body

This parenteral preparation is indicated only for diluting or dissolving drugs for intravenous, intramuscular or subcutaneous injection, according to instructions of the manufacturer of the drug to be administered.

Why people take it. This parenteral preparation is indicated only for diluting or dissolving drugs for intravenous, intramuscular or subcutaneous injection, according to instructions of the manufacturer of the drug to be administered.

What happened in people

RNAWiki has not yet published a reviewed conclusion for this use.

A fixed RNAWiki sentence

Where this came from

Wording RNAWiki always uses, not a finding about this substance.

No reviewed claim names a result for any goal on this record.

No source is stored against this line.

The limit that matters most

Not recorded.

Where it acts
Not recorded.
Kind of result
No result is published, so no kind of result applies yet
Supervision
RNAWiki has not recorded a supervision or regulatory status for this substance.
Where each sentence above came from

The use the label states, quoted from it. No plain-language version of this sentence has been written.

The use the label states, quoted from it. It is written for a clinician, not for a reader without medical training.

No statement of the main limit is recorded.

The four opening statements run to 71 words.

Words this page uses

Four words worth knowing first

Chosen from what this page shows, with each one explained before the word it depends on.

Biomarker

A biomarker is a number from a test that stands in for something about health.

A picture of it, and where the picture fails

A biomarker is like a fuel gauge.

Where that stops being true. A gauge is wired to the tank. Many biomarkers are only loosely tied to health.

What people get wrong. A better number is read as a better life. Several medicines improved a number and helped nobody.

A measurable indicator used as a substitute for a clinical outcome of interest.

Placebo

A placebo is a dummy treatment given so the real one can be compared with it.

A picture of it, and where the picture fails

A placebo is like a blank control in an experiment.

Where that stops being true. A blank does nothing. People given a placebo often do get better.

What people get wrong. A placebo effect is read as imaginary. The improvement is measured and real.

An inactive intervention matched in appearance to the test intervention, used to control for non-specific effects.

Comparator

A comparator is whatever the treatment was measured against.

A picture of it, and where the picture fails

It is like the other runner in a race.

Where that stops being true. A race has one winner. A study can show both arms improved.

What people get wrong. Results are read without asking what the other group got. Beating nothing is not beating a treatment.

The control condition against which the experimental intervention is assessed.

What happened in peopleRead from sources, not yet reviewed

What happened in people

Each card is one study: the exact question it asked, who was in it, and whether it showed what it set out to show.

Adenoma detection rate

The study did not show it

Who was studied
NCT02135601
How many people
3303
Study design
Not applicable
Compared against
Not recorded for this study
Kind of result
A number that stands in for health
What was found
Result not recorded on this page
Repeated elsewhere
Unreplicated

What this does not prove. A study that did not show an effect does not show that no effect exists anywhere.

The limits of this study, and where it came from

Main limit. No limitation is recorded for this study.

How far it carries. This study is recorded from the curated record, not from the registry match.

Form and route.

Interval reported. Not recorded in this summary

Written into the record, not signed off as a reviewed claim.

  • openFDA Drugs@FDA · a recorded source, not a stored snapshot
  • PubChem PUG-REST · a recorded source, not a stored snapshot
  • GBIF Backbone Taxonomy · a recorded source, not a stored snapshot
  • Europe PMC · a recorded source, not a stored snapshot

Incidence of incisional surgical site infection (SSI)

The study did not show it

Who was studied
NCT04548661
How many people
2701
Study design
Not applicable
Compared against
Not recorded for this study
Kind of result
A number that stands in for health
What was found
Result not recorded on this page
Repeated elsewhere
Unreplicated

What this does not prove. A study that did not show an effect does not show that no effect exists anywhere.

The limits of this study, and where it came from

Main limit. No limitation is recorded for this study.

How far it carries. This study is recorded from the curated record, not from the registry match.

Form and route.

Interval reported. Not recorded in this summary

Written into the record, not signed off as a reviewed claim.

  • openFDA Drugs@FDA · a recorded source, not a stored snapshot
  • PubChem PUG-REST · a recorded source, not a stored snapshot
  • GBIF Backbone Taxonomy · a recorded source, not a stored snapshot
  • Europe PMC · a recorded source, not a stored snapshot

evaluation of disease recurrence reduction (cervical intraepithelial neoplasia up to microinvasive cancer of the cervix)

The study did not show it

Who was studied
NCT03848039
How many people
1220
Study design
Phase 3
Compared against
Not recorded for this study
Kind of result
A number that stands in for health
What was found
Result not recorded on this page
Repeated elsewhere
Unreplicated

What this does not prove. A study that did not show an effect does not show that no effect exists anywhere.

The limits of this study, and where it came from

Main limit. No limitation is recorded for this study.

How far it carries. This study is recorded from the curated record, not from the registry match.

Form and route.

Interval reported. Not recorded in this summary

Written into the record, not signed off as a reviewed claim.

  • openFDA Drugs@FDA · a recorded source, not a stored snapshot
  • PubChem PUG-REST · a recorded source, not a stored snapshot
  • GBIF Backbone Taxonomy · a recorded source, not a stored snapshot
  • Europe PMC · a recorded source, not a stored snapshot

Incidence of Post-ERCP Pancreatitis (PEP) between the cold water and control groups

The study did not show it

Who was studied
NCT07330284
How many people
950
Study design
Not applicable
Compared against
Not recorded for this study
Kind of result
A number that stands in for health
What was found
Result not recorded on this page
Repeated elsewhere
Unreplicated

What this does not prove. A study that did not show an effect does not show that no effect exists anywhere.

The limits of this study, and where it came from

Main limit. No limitation is recorded for this study.

How far it carries. This study is recorded from the curated record, not from the registry match.

Form and route.

Interval reported. Not recorded in this summary

Written into the record, not signed off as a reviewed claim.

  • openFDA Drugs@FDA · a recorded source, not a stored snapshot
  • PubChem PUG-REST · a recorded source, not a stored snapshot
  • GBIF Backbone Taxonomy · a recorded source, not a stored snapshot
  • Europe PMC · a recorded source, not a stored snapshot

Overall Survival

The study did not show it

Who was studied
NCT02757859
How many people
845
Study design
Not applicable
Compared against
Not recorded for this study
Kind of result
Living longer, or avoiding a major event
What was found
Result not recorded on this page
Repeated elsewhere
Unreplicated

What this does not prove. A study that did not show an effect does not show that no effect exists anywhere.

The limits of this study, and where it came from

Main limit. No limitation is recorded for this study.

How far it carries. This study is recorded from the curated record, not from the registry match.

Form and route.

Interval reported. Not recorded in this summary

Written into the record, not signed off as a reviewed claim.

  • openFDA Drugs@FDA · a recorded source, not a stored snapshot
  • PubChem PUG-REST · a recorded source, not a stored snapshot
  • GBIF Backbone Taxonomy · a recorded source, not a stored snapshot
  • Europe PMC · a recorded source, not a stored snapshot

number of patients undergoing complete unsedated or slightly sedated colonoscopy

The study did not show it

Who was studied
NCT01463319
How many people
818
Study design
Early phase 1
Compared against
Not recorded for this study
Kind of result
A number that stands in for health
What was found
Result not recorded on this page
Repeated elsewhere
Unreplicated

What this does not prove. A study that did not show an effect does not show that no effect exists anywhere.

The limits of this study, and where it came from

Main limit. No limitation is recorded for this study.

How far it carries. This study is recorded from the curated record, not from the registry match.

Form and route.

Interval reported. Not recorded in this summary

Written into the record, not signed off as a reviewed claim.

  • openFDA Drugs@FDA · a recorded source, not a stored snapshot
  • PubChem PUG-REST · a recorded source, not a stored snapshot
  • GBIF Backbone Taxonomy · a recorded source, not a stored snapshot
  • Europe PMC · a recorded source, not a stored snapshot
What we know
RNAWiki holds 6 written-up human studies for this substance, each with the question it asked.
How we know it
Each card names the study, the number of people and what the study set out to measure.
What this does not prove
These summaries were written by a person and have not been signed off as reviewed claims.
Why it matters
A study that failed is as informative as one that worked, and both are here.
What we still do not know
No reviewed claim exists, so no exact population, effect size or interval is published yet.

What is missing or unclearRead from sources, not yet reviewed

Were people like you studied?

RNAWiki cannot tell whether a study fits you. It can show who was in it, and where the result stops carrying.

Who was studied

No description of who was studied is recorded.

Who is missing from the studies

  • Which groups were under-represented in the studies has not been recorded for this substance. Pregnancy, breastfeeding, children, older adults, and people with liver or kidney conditions are commonly excluded from trials; nothing here says whether they were.

What the label states about particular groups

  • On pediatric, the label states: “Safety and effectiveness have been established in pediatric patients.”

    US prescribing information · 3f49eedf-5bf5-4a95-b704-c956d860ca04 · read 2026-08-30

  • On people who are pregnant, the label states: “Animal reproduction studies have not been conducted with Sterile Water for Injection.”

    US prescribing information · 3f49eedf-5bf5-4a95-b704-c956d860ca04 · read 2026-08-30

Where the result stopped carrying

  • This is a scope explorer, not a diagnosis engine.
  • It shows who was studied so you can see whether people similar to you were included.

RNAWiki cannot tell whether a study fits you. It can show who was in it.

What it would be like to takeRead from sources, not yet reviewed

Why it might seem to do nothing

A real effect and a noticed effect are different things. These are the recorded reasons the two come apart.

It was studied in different people

The people in the studies were not much like the reader.

On this record: Which groups were under-represented in the studies has not been recorded for this substance. Pregnancy, breastfeeding, children, older adults, and people with liver or kidney conditions are commonly excluded from trials; nothing here says whether they were.

The evidence may simply be wrong

Small early studies often do not hold up.

On this record: RNAWiki has not yet published a reviewed conclusion for this use.

Other reasons RNAWiki checked and found nothing for (11)
It was studied for a different goal
The studies measured something else entirely. Nothing in this record points to this reason.
A different form was studied
The studied form is not the form on the shelf. Nothing in this record points to this reason.
There was nothing to correct
Where a level is already normal, topping it up may change nothing. Nothing in this record points to this reason.
Something else had to happen too
In the studies it was paired with training, a diet or another treatment. Nothing in this record points to this reason.
The change is too small to feel
A real change can still sit below what a person notices. Nothing in this record points to this reason.
Day-to-day swing hides it
Sleep, food, stress and time of day move most numbers more than this would. Nothing in this record points to this reason.
Not enough time yet
The studies ran longer than the person has waited. Nothing in this record points to this reason.
It was not taken as studied
Missed days change the result, and studies count them. Nothing in this record points to this reason.
Something else changed at the same time
Two changes at once cannot be told apart afterwards. Nothing in this record points to this reason.
The product may not be what it says
Contents of a sold product are not always what the label states. Nothing in this record points to this reason.
No recorded reason
RNAWiki has nothing stored that would explain it. Nothing in this record points to this reason.

None of these is a reason to take more. Taking more is not a step this page ever suggests.

What it would be like to takeRead from sources, not yet reviewed

What taking it involves

The recorded facts about getting hold of it and using it. Nothing here is a suggestion about what you should do.

How it is supplied

Prescription only

Quoted from a source

Where this came from

Copied from a source RNAWiki stored, with the source named.

Read from the recorded approval status.

No source is stored against this line.

Form and route

Not recorded.

Nothing recorded

Where this came from

RNAWiki holds nothing here and says so rather than guessing.

No form or route is recorded.

No source is stored against this line.

Who oversees it

RNAWiki has not recorded a supervision or regulatory status for this substance.

Quoted from a source

Where this came from

Copied from a source RNAWiki stored, with the source named.

No register row and no identity class settled the question.

No source is stored against this line.

What is in the pack

Not recorded.

Nothing recorded

Where this came from

RNAWiki holds nothing here and says so rather than guessing.

Nothing is recorded about product quality.

No source is stored against this line.

Where it is registered

Regulatory records are listed in the technical disclosure at the foot of this page.

Counted from records

Where this came from

A count of rows RNAWiki holds. It describes our records, not your body.

Register entries are stored per jurisdiction and shown with their dates.

No source is stored against this line.

Why people stop

Not recorded.

Nothing recorded

Where this came from

RNAWiki holds nothing here and says so rather than guessing.

No record of why people stopped taking it is stored for this substance.

No source is stored against this line.

What it would be like to takeNothing found in the sources checked

What can go wrong

Sorted by where each line came from. A regulator's label and a report somebody sent in are not the same kind of fact.

Nothing found in the sources checked

No harm is recorded against this substance in the sources RNAWiki checked. Finding nothing is not the same as showing there is nothing.

The sources listed were searched and held nothing. That is not the same as nothing existing.

Over a long time. No completed tested study window is recorded, so long-term effects are not established by the registry record.

Groups the studies covered thinly. Which groups were under-represented in the studies has not been recorded for this substance. Pregnancy, breastfeeding, children, older adults, and people with liver or kidney conditions are commonly excluded from trials; nothing here says whether they were.

What is missing or unclearRead from sources, not yet reviewed

Does the exact form matter?

Evidence belongs to the exact thing that was tested. A different salt, a different mixture or a different preparation is a different question.

The form that was studied

Not recorded.

Nothing recorded

Where this came from

RNAWiki holds nothing here and says so rather than guessing.

The exact form studied is not recorded.

No source is stored against this line.

What is sold

Not recorded.

Nothing recorded

Where this came from

RNAWiki holds nothing here and says so rather than guessing.

Nothing further is recorded about which forms are sold.

No source is stored against this line.

What is recorded as being sold

  • Sterile Water is intramuscular at HOW SUPPLIED Sterile Water for Injection, USP is supplied in the following: 10 mL single dose vials packaged in cartons of 10 vials (NDC 72572- 747 -10) Storage Store at 20° to 25°C (68° to 77°F) [See USP Controlled Roo…, recorded as fda label in effect 2023-04-07 in the United States.

    US prescribing information · 3f49eedf-5bf5-4a95-b704-c956d860ca04 · read 2026-08-30

Evidence carries across two names for one substance. It does not carry across a salt, a mirror form or a mixture.

What it would be like to takeRead from sources, not yet reviewed

What you could measure

This one is decided with a clinician, so this section holds questions to ask rather than a plan to run.

RNAWiki could not confidently classify this substance, so no self-experiment plan is offered.

Questions worth asking

  • Which of the trials of Aqua studied people like me?
  • What was measured, and for how long?
  • Was the result a laboratory value or a health outcome?
  • What would we watch for, and when would we stop?

Tracking can show whether something changed for you. It cannot show what caused it.

RNAWiki records evidence. It does not say whether this substance is right for you.

What is missing or unclearRead from sources, not yet reviewed

What nobody knows yet

Open questions, each with why it is open and what would close it.

Missing populations

Which groups were under-represented in the studies has not been recorded.

Why it matters. Recorded by the evidence model as a gap on this record.

What would answer it

A study that measures it, and a reviewer to sign it off.

Last checked 2026-09-04. Searched: The sources listed in the receipts at the foot of this page.

Missing long-term data

No completed tested study window is recorded.

Why it matters. Recorded by the evidence model as a gap on this record.

What would answer it

A study that measures it, and a reviewer to sign it off.

Last checked 2026-09-04. Searched: The sources listed in the receipts at the foot of this page.

No reviewed conclusion

RNAWiki has not yet published a reviewed conclusion for this use.

Why it matters. Recorded by the evidence model as a gap on this record.

What would answer it

A study that measures it, and a reviewer to sign it off.

Last checked 2026-09-04. Searched: The sources listed in the receipts at the foot of this page.

Missing interaction studies

No interaction was found in the registers checked. Not finding one is not the same as showing there is none.

Why it matters. Recorded by the evidence model as a gap on this record.

What would answer it

A study that measures it, and a reviewer to sign it off.

Last checked 2026-09-04. Searched: The sources listed in the receipts at the foot of this page.

Formulation uncertainty

Several salts, forms or products of Aqua are recorded. Results from one form may not transfer to another.

Why it matters. Recorded by the evidence model as a gap on this record.

What would answer it

A study that measures it, and a reviewer to sign it off.

Last checked 2026-09-04. Searched: The sources listed in the receipts at the foot of this page.

Mechanism not reviewed

No reviewed mechanism story exists for this substance.

Why it matters. Recorded by the evidence model as a gap on this record.

What would answer it

A study that measures it, and a reviewer to sign it off.

Last checked 2026-09-04. Searched: The sources listed in the receipts at the foot of this page.

What happened in peopleNothing found in the sources checked

Check any of this yourself

Every line above traced back to the study it came from. This is the technical layer, and the vocabulary changes here.

Nothing found in the sources checked

No traced study record is stored for this substance.

The sources listed were searched and held nothing. That is not the same as nothing existing.

Checks this page had to pass

  • Passed

    Identity resolved

    no open identity hold

  • Passed

    No unresolved merge across substance families

    no quarantine open

  • Passed

    Every public sentence names a source

    The opening statement carries the origin: Quoted from a stored source.

  • Not passed

    Trial roles classified for highlighted evidence

    No registered study is classified as testing this substance.

  • Passed

    No internal keys in reader text

    enforced by the copy-contract test over the rendered page

  • Not passed

    Safety mode resolved

    No register row and no identity class settled the question.

  • Passed

    Canonical metadata present

    slug and display name present

What is missing or unclearRead from sources, not yet reviewed

How this medicine reached us

Kept near the foot of the page. A historical event moves up only when it changes something about this substance today.

  1. Withdrawn in United States, 2021, for "Temperature Abuse: product samples were stored at temperatures below 32* F which is not in accordance with storage requirements that could cause a lack of efficacy and damage to the cartridge and…" (openFDA drug enforcement Class I recall)

  2. Withdrawn in United States, 2022, for "TEMPERATURE ABUSE: Products were exposed to temperatures outside of the products labeled storage conditions due to inclement weather." (openFDA drug enforcement Class I recall)

What the approval register records

  • 7 approved applications cover products containing this substance. The earliest was NDA016734, approved 19700910 to B BRAUN.

    Drugs@FDA application register · NDA016734 · read 2026-08-29

  • Marketing status on the register: discontinued and prescription.

    Drugs@FDA application register · NDA016734 · read 2026-08-29

What is missing or unclearRead from sources, not yet reviewed

What to learn next

Ordered by what would most change how you read this page, starting with what is easiest to misunderstand.

This order is fixed in code and does not count clicks or time on the page.

What is not here

9 questions this page could not answer

These sections were prepared and left out because there was nothing to put in them. They are listed rather than hidden, so the gaps in this record are visible.

  • What was measured, goal by goal — found nothing in the sources checked.
  • How close this is to real life — found nothing in the sources checked.
  • The path through the body — found nothing in the sources checked.
  • Felt, measured, or meaningful — found nothing in the sources checked.
  • How long anything takes — found nothing in the sources checked.
  • What it may clash with — found nothing in the sources checked.
  • Other ways to the same goal — found nothing in the sources checked.
  • Claims that go past the evidence — found nothing in the sources checked.
  • What changed on this page — found nothing in the sources checked.

The record as stored

The full record, for auditing

Everything above is built from what is below. This layer keeps the technical vocabulary, record identifiers and every stored row, so a reader who wants to check the page can.

Recorded evidence blocks (9)

On the Aqua label: indicated for what?


"This parenteral preparation is indicated only for diluting or dissolving drugs for intravenous, intramuscular, or subcutaneous injection, according to instructions of the manufacturer of the drug to be administered.": indications and usage on Aqua's label. DailyMed label · bc04a883-babc-87a6-e053-2995a90a3dfd · 2025-07-11

146 registered trials of Aqua — at which phases?


Registered studies posting no result
126 of 146

146 registered studies of Aqua: 54 na, 42 phase2, 24 phase4, 23 phase3, 13 phase1, 5 early phase1. CLINICALTRIALS_SNAPSHOT · 2026-09-01

147 with a PubMed record

Show the evidence
  • na
    54
  • phase2
    42
  • phase4
    24
  • phase3
    23
  • phase1
    13
  • early phase1
    5
8 more recorded rows
  • completed
    85
  • unknown
    30
  • terminated
    10
  • recruiting
    8
  • active not recruiting
    5
  • withdrawn
    4
  • not yet recruiting
    3
  • enrolling by invitation
    1

recorded 2026-09-01 · last checked 2026-09-04

12 of Aqua's trials stopped: safety, funding/business, other?


safety (2), funding/business (3) and other (7): Aqua's stop wording, clustered. CLINICALTRIALS_SNAPSHOT · 2026-09-01

"Terminated for futility on 11/30/09 based on the recommendation of the DSMB"; 12 of 146 registered studies

Show the evidence

Trial

  • NCT00395161
    terminated; "Terminated for futility on 11/30/09 based on the recommendation of the DSMB"
  • NCT01289808
    terminated; "changes were made to the which needed an entireley new submission"
  • NCT01723501
    withdrawn; "The study was not started and prematurely closed."
  • NCT01795638
    terminated; "The unit's standard nutrition practices change which impacted our methodology."
  • NCT02374853
    terminated; "the preliminary analysis of study result did not show significant benefit that was anticipate"
  • NCT02959112
    terminated; "Because previous studies had found no difference, and one recent study even reported a higher incidence of PEP in treatment arm"
6 further recorded trials
  • NCT03787082
    withdrawn; "Study was never able to start after the pandemic restrictions lifted"
  • NCT04264533
    terminated; "the study was started in the second half of the outbreak, and the number of qualifying COVID-19 patients decreased with the control of the epidemic so that we had to stop our trial before reaching the predefined sample size."
  • NCT04274517
    terminated; "Preliminary analysis showed lack of positive finding, indicating a substantial number of subjects required, which is not feasible based on budget and timeline."
  • NCT04748783
    terminated; "Funding withdrawn"
  • NCT04777383
    terminated; "The study was terminated prematurely due to insufficient operational resources to continue trial conduct and completion. The decision was unrelated to safety concerns or study outcomes."
  • NCT06845358
    withdrawn; "Study not implemented due to funding."

recorded 2026-09-01 · last checked 2026-09-04

Human studies of Aqua used Sterile water, 100 ml, Braun — over how long?


Human studies of Aqua used "Sterile water, 100 ml, Braun". ClinicalTrials.gov · 2026-09-01

2 recorded entries; human; also "Calcium Hydroxide (20%)"

Show the evidence

human

  • NCT04777383
    Sterile water, 100 ml, Braun
  • NCT07123792
    Calcium Hydroxide (20%)

recorded 2026-09-01 · last checked 2026-09-04

Which running trial of Aqua could settle lifespan?


NCT03998319 measures To compare the number of participants who experience cardiovascular mortality and rehospitalisation for heart failure at 24 months in those given tenecteplase with those given placebo (Cardiac MRI cohort only), reading out 2026-12-31.

1 open trial; n 445; "A Study of Low-dose Intracoronary Thrombolytic Therapy in STEMI (Heart Attack) Patients."

Show the evidence
  • Trial NCT03998319
    "A Study of Low-dose Intracoronary Thrombolytic Therapy in STEMI (Heart Attack) Patients."; n 445; "To compare the number of participants who experience cardiovascular mortality and rehospitalisation for heart failure at 24 months in those given tenecteplase with those given placebo (Cardiac MRI cohort only)"; 2026-12-31

Which 62 trials of Aqua posted no result?


Posted no result
62 of 62 completed trials
Registrations
NCT00218946, NCT00694174, NCT00446875, NCT00405444, NCT00921544 and NCT00927979, and 56 more
Completion dates
oldest 2007-08; newest 2024-07-01
Show the evidence

Trial

  • NCT00218946
    2007-08
  • NCT00694174
    2007-09
  • NCT00446875
    2008-05-19
  • NCT00405444
    2008-09
  • NCT00921544
    2009-03
  • NCT00927979
    2010-10
14 further recorded trials
  • NCT01369589
    2011-04
  • NCT00472173
    2011-05
  • NCT01181570
    2011-09
  • NCT01558986
    2011-09
  • NCT01348386
    2012-03
  • NCT01428375
    2012-10
  • NCT01566201
    2013-06
  • NCT01558375
    2014-02
  • NCT02697994
    2014-03
  • NCT03336970
    2014-06-01
  • NCT02284412
    2015-04
  • NCT03606681
    2015-06
  • NCT03042377
    2015-08-30
  • NCT02059655
    2016-03

At the median, Aqua's trials enrolled 60 people — anything larger?


Median enrolment
60
Largest enrolment
9180
Registered trials counted
146

What do 353 spontaneous reports say about Aqua — and not say?


These are reports people sent to a regulator. They do not show the medicine caused the reaction. Nobody counted how many people took the medicine and reported nothing. The same event can be reported more than once, and many reports are incomplete. News coverage, lawsuits and new warnings change how often people report. A count is not a rate and not a risk.

Aqua appears in spontaneous reports to regulators. Across the 10 most-reported reaction terms, 353 reaction mentions were counted: injection site erythema 62; wrong drug administered 50; malaise 47; injection site pain 45. FAERS via Open Targets · CHEMBL1098659 · 2026-06-24

Show the evidence
  • injection site erythema
    62
  • wrong drug administered
    50
  • malaise
    47
  • injection site pain
    45
  • herpes zoster
    32
  • bone marrow failure
    26
4 more recorded rows
  • injection site pruritus
    25
  • flushing
    24
  • corneal opacity
    22
  • injection site swelling
    20

recorded 2026-06-24 · last checked 2026-09-04

Which 10 reactions does Aqua's label not list?


bone marrow failure, corneal opacity and flushing and 7 more reported for Aqua, absent from its label. FAERS via Open Targets · CHEMBL1098659 · 2026-06-24

3 label terms; 10 reported and unlisted; bc04a883-babc-87a6-e053-2995a90a3dfd

Show the evidence
  • bone marrow failure
    count not stated
  • corneal opacity
    count not stated
  • flushing
    count not stated
  • herpes zoster
    count not stated
  • injection site erythema
    count not stated
  • injection site pain
    count not stated
4 more recorded rows
  • injection site pruritus
    count not stated
  • injection site swelling
    count not stated
  • malaise
    count not stated
  • wrong drug administered
    count not stated

recorded 2026-06-24 · last checked 2026-09-04

Where it is registered

Where it’s registered

Withdrawn in United States, 2021, for "Temperature Abuse: product samples were stored at temperatures below 32* F which is not in accordance with storage requirements that could cause a lack of efficacy and damage to the cartridge and…" (openFDA drug enforcement Class I recall)

Withdrawn in United States, 2022, for "TEMPERATURE ABUSE: Products were exposed to temperatures outside of the products labeled storage conditions due to inclement weather." (openFDA drug enforcement Class I recall)

Identifiers, relations and other names

The exact record

ChEMBL id
CHEMBL1098659
PubChem CID
962
CAS number
7732-18-5
RxCUI
11295
InChIKey
XLYOFNOQVPJJNP-UHFFFAOYSA-N
Also called
WATER, Adelheid aqua, Adelheidsquelle, Aqua adelheid, Aqua pro injectione, Aqua purificata, Aqua sterilisata pro injectione, Aqua wiesbaden, Aqua wildbad, Purified water, Sterile purified water, Sterile water for inhalation
Development code
B1217, NSC-147337, R-718
Trade name
Pur-wash, Sterile water, Ximonth Fungi Free Bee Venom Nail Soothing Serum, Bestmade Natural Products Field of Flowers Formula, Ximonth Fungi Free Bee Venom Nail Soothing Serum / Bestmade Natural Products Field of Flowers Formula, Ohtrust Nano Ion Water, Ohtrust Mouth and Nasal Relief, Ohtrust Nano Ion Water / Ohtrust Mouth and Nasal Relief, Mdfarma Cold and Flu Relief, Sterile Water in Plastic Container, Sterile Water in Plastic Container / Sterile Water
Salt form
Sterile water for injection, Water,bacteriostatic injection, Water for injection, HYDROXIDE IONS, Sterile Water For Injection in Plastic Container, Bacteriostatic Water For Injection in Plastic Container, Sterile Water For Injection in Plastic Container / Bacteriostatic Water For Injection in Plastic Container
Sources (7)

Sources

1 more source

ChEMBL 37 — CC BY-SA 3.0 Unported · ClinicalTrials.gov — US Government work · Open Targets 26.06 — CC0 · mixed register set; per-register licences in docs/specs/corpus-20k-sources.md · openFDA / DailyMed — US Government work · openFDA enforcement — US Government work

How these records are assembled · Which registers were checked

Index-quality checks
  • identity passed: no open identity hold
  • required summary fields resolved: 3 required field(s) not terminal: Best-supported result, Biggest unanswered question, Human evidence
  • public claims reviewed: 0 reviewed claim(s); drafts are never rendered
  • source coverage passed: 7 source rows
  • no critical contamination: no quarantine open
  • canonical metadata passed: slug and display name present
  • no raw internal fields: enforced by the copy-contract test over the rendered page

This is a record of evidence. It is not medical advice, and it does not say this substance suits you. Nothing here says any substance on RNAWiki is appropriate for a child.