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Silver Phosphate

  • Plant preparation
  • Varies by country
  • Identity checked
  • Sources last checked 2026-09-04

This page shows what was measured, who it was measured in, and what that does not settle.

What Silver Phosphate does in the body

for Use For relief of symptoms due to skin eruptions from acne, eczema, minor infection, rashes, blisters -Sunburn – Razor Burn – minor nicks & cuts – redness – minor inflammation

Why people take it. for Use For relief of symptoms due to skin eruptions from acne, eczema, minor infection, rashes, blisters -Sunburn – Razor Burn – minor nicks & cuts – redness – minor inflammation

What happened in people

RNAWiki has not yet published a reviewed conclusion for this use.

A fixed RNAWiki sentence

Where this came from

Wording RNAWiki always uses, not a finding about this substance.

No reviewed claim names a result for any goal on this record.

No source is stored against this line.

The limit that matters most

Not recorded.

Where it acts
Not recorded.
Kind of result
No result is published, so no kind of result applies yet
Supervision
Not usually supervised: sold as a supplement or food ingredient where recorded. That is a legal category, not a safety judgement.

What the registries record it as

  • The substance registry classes this as chemical.

    FDA substance registry · ZL6T4Y1XP8 · read 2026-08-29

  • The supplement label database classes it as botanical, under the name Silver (usp).

    NIH Dietary Supplement Label Database · 599 · read 2026-08-29

Where each sentence above came from

The use the label states, quoted from it. No plain-language version of this sentence has been written.

The use the label states, quoted from it. It is written for a clinician, not for a reader without medical training.

No statement of the main limit is recorded.

The four opening statements run to 65 words.

Words this page uses

Four words worth knowing first

Chosen from what this page shows, with each one explained before the word it depends on.

Protein

A protein is a folded chain your body builds to do a specific job.

A picture of it, and where the picture fails

A protein is like a tool bent into one shape for one task.

Where that stops being true. A tool keeps its shape. A protein can change shape and stop working.

What people get wrong. Protein in food and a protein in the body are related but not the same thing.

A polymer of amino acids folded into a defined structure that determines its function.

Enzyme

An enzyme is a protein that speeds up one chemical change.

A picture of it, and where the picture fails

An enzyme is like a machine on a production line doing one cut.

Where that stops being true. A machine is switched on and off by a person. Enzymes are controlled by the cell.

What people get wrong. Enzymes are thought to be used up. They are not; they work again and again.

A catalytic protein that lowers the activation energy of a specific reaction.

Receptor

A receptor is a part of a cell that a signal fits into.

A picture of it, and where the picture fails

A receptor is like a lock waiting for one key.

Where that stops being true. A lock either opens or does not. A receptor can be half-triggered, or worn out.

What people get wrong. Fitting a receptor is read as causing a benefit. It causes a step, and nothing more.

A protein that binds a specific ligand and converts that binding into a cellular response.

Pathway

A pathway is a chain of steps inside a cell, each one setting off the next.

A picture of it, and where the picture fails

A pathway is like a row of dominoes.

Where that stops being true. Dominoes fall one way. Pathways loop back and can switch themselves off.

What people get wrong. Changing one step is read as changing the outcome. Other steps often absorb it.

An ordered series of molecular interactions producing a defined cellular change.

What happened in peopleRead from sources, not yet reviewed

What happened in people

Each card is one study: the exact question it asked, who was in it, and whether it showed what it set out to show.

Time to a composite endpoint of cardiovascular death or non-fatal major cardiovascular event

The study did not show it

Who was studied
NCT03573089
How many people
3600
Study design
Not applicable
Compared against
Not recorded for this study
Kind of result
Living longer, or avoiding a major event
What was found
Result not recorded on this page
Repeated elsewhere
Unreplicated

What this does not prove. A study that did not show an effect does not show that no effect exists anywhere.

The limits of this study, and where it came from

Main limit. No limitation is recorded for this study.

How far it carries. This study is recorded from the curated record, not from the registry match.

Form and route.

Interval reported. Not recorded in this summary

Written into the record, not signed off as a reviewed claim.

  • openFDA NDC Directory · a recorded source, not a stored snapshot
  • openFDA Drugs@FDA · a recorded source, not a stored snapshot
  • Europe PMC · a recorded source, not a stored snapshot
  • ClinicalTrials.gov · a recorded source, not a stored snapshot

Progression-free Survival (PFS) Rate at 3 Years

The study did not show it

Who was studied
NCT02048813
How many people
529
Study design
Phase 3
Compared against
Not recorded for this study
Kind of result
Living longer, or avoiding a major event
What was found
Result not recorded on this page
Repeated elsewhere
Unreplicated

What this does not prove. A study that did not show an effect does not show that no effect exists anywhere.

The limits of this study, and where it came from

Main limit. No limitation is recorded for this study.

How far it carries. This study is recorded from the curated record, not from the registry match.

Form and route.

Interval reported. Not recorded in this summary

Written into the record, not signed off as a reviewed claim.

  • openFDA NDC Directory · a recorded source, not a stored snapshot
  • openFDA Drugs@FDA · a recorded source, not a stored snapshot
  • Europe PMC · a recorded source, not a stored snapshot
  • ClinicalTrials.gov · a recorded source, not a stored snapshot

The hardness of cavity on tooth by probing

The study did not show it

Who was studied
NCT03423797
How many people
408
Study design
Phase 3
Compared against
Not recorded for this study
Kind of result
A number that stands in for health
What was found
Result not recorded on this page
Repeated elsewhere
Unreplicated

What this does not prove. A study that did not show an effect does not show that no effect exists anywhere.

The limits of this study, and where it came from

Main limit. No limitation is recorded for this study.

How far it carries. This study is recorded from the curated record, not from the registry match.

Form and route.

Interval reported. Not recorded in this summary

Written into the record, not signed off as a reviewed claim.

  • openFDA NDC Directory · a recorded source, not a stored snapshot
  • openFDA Drugs@FDA · a recorded source, not a stored snapshot
  • Europe PMC · a recorded source, not a stored snapshot
  • ClinicalTrials.gov · a recorded source, not a stored snapshot

Progression Free Survival (PFS): Intent-to-Treat (ITT) Population By Interactive Web Recognition System (IWRS)

The study did not show it

Who was studied
NCT02007512
How many people
247
Study design
Phase 2
Compared against
Not recorded for this study
Kind of result
Living longer, or avoiding a major event
What was found
Result not recorded on this page
Repeated elsewhere
Unreplicated

What this does not prove. A study that did not show an effect does not show that no effect exists anywhere.

The limits of this study, and where it came from

Main limit. No limitation is recorded for this study.

How far it carries. This study is recorded from the curated record, not from the registry match.

Form and route.

Interval reported. Not recorded in this summary

Written into the record, not signed off as a reviewed claim.

  • openFDA NDC Directory · a recorded source, not a stored snapshot
  • openFDA Drugs@FDA · a recorded source, not a stored snapshot
  • Europe PMC · a recorded source, not a stored snapshot
  • ClinicalTrials.gov · a recorded source, not a stored snapshot

Dose-limiting Toxicities (Phase I)

The study did not show it

Who was studied
NCT02713386
How many people
147
Study design
Phase 1/Phase 2
Compared against
Not recorded for this study
Kind of result
A number that stands in for health
What was found
Result not recorded on this page
Repeated elsewhere
Unreplicated

What this does not prove. A study that did not show an effect does not show that no effect exists anywhere.

The limits of this study, and where it came from

Main limit. No limitation is recorded for this study.

How far it carries. This study is recorded from the curated record, not from the registry match.

Form and route.

Interval reported. Not recorded in this summary

Written into the record, not signed off as a reviewed claim.

  • openFDA NDC Directory · a recorded source, not a stored snapshot
  • openFDA Drugs@FDA · a recorded source, not a stored snapshot
  • Europe PMC · a recorded source, not a stored snapshot
  • ClinicalTrials.gov · a recorded source, not a stored snapshot

Percentage of Participants Maintaining Mean Hemoglobin Levels Within the Target Range During the Last 4 Weeks of the Treatment Period (Weeks 8 to 12)

The study did not show it

Who was studied
NCT00737464
How many people
132
Study design
Phase 4
Compared against
Not recorded for this study
Kind of result
A number that stands in for health
What was found
Result not recorded on this page
Repeated elsewhere
Unreplicated

What this does not prove. A study that did not show an effect does not show that no effect exists anywhere.

The limits of this study, and where it came from

Main limit. No limitation is recorded for this study.

How far it carries. This study is recorded from the curated record, not from the registry match.

Form and route.

Interval reported. Not recorded in this summary

Written into the record, not signed off as a reviewed claim.

  • openFDA NDC Directory · a recorded source, not a stored snapshot
  • openFDA Drugs@FDA · a recorded source, not a stored snapshot
  • Europe PMC · a recorded source, not a stored snapshot
  • ClinicalTrials.gov · a recorded source, not a stored snapshot
What we know
RNAWiki holds 6 written-up human studies for this substance, each with the question it asked.
How we know it
Each card names the study, the number of people and what the study set out to measure.
What this does not prove
These summaries were written by a person and have not been signed off as reviewed claims.
Why it matters
A study that failed is as informative as one that worked, and both are here.
What we still do not know
No reviewed claim exists, so no exact population, effect size or interval is published yet.

What happened in peopleRead from sources, not yet reviewed

How close this is to real life

The top step is something a person would feel or care about. The bottom is a guess from software. Filled steps are where evidence exists for this substance.

  1. Living longer, or avoiding a major event No evidence recorded. Death, a heart attack, a stroke, a hospital stay.0 registered measures of this kind. 3 written-up studies measured this and did not show a benefit.
  2. What a body can do day to day No evidence recorded. Walking, dressing, breathing, recovering.No registered study measures this.
  3. Measured performance No evidence recorded. How much was lifted, how far was run, how fast.No registered study measures this.
  4. Symptoms and quality of life No evidence recorded. Pain, tiredness, mood, sleep, as the person rated it.No registered study measures this.
  5. A number that stands in for health No evidence recorded. Cholesterol, blood sugar, bone density. A stand-in, not the thing itself.No registered study measures this.
  6. A step measured inside a person Evidence recorded. Something measured in human tissue or human cells.A human record sits on the stored organism ladder.
  7. Animals Evidence recorded. Mice, rats, dogs. Useful for ideas, not proof about people.Stored records in Yeast, C. elegans (roundworm), Drosophila (fruit fly), Mouse, Rat, Dog. A result in animals says what to test next. It does not say what happens in people.
  8. Cells in a dish Evidence recorded. Cells or chemistry on a bench, far from a whole body.Stored mechanism abstracts describe steps measured in cells or tissue.
  9. A guess from software No evidence recorded. Nobody measured it. RNAWiki never publishes one as a finding.RNAWiki stores no prediction for this record. Software can suggest a link. RNAWiki does not publish one as a finding.

Higher on these steps means closer to something a person would feel. It does not mean better done.

What is missing or unclearRead from sources, not yet reviewed

Were people like you studied?

RNAWiki cannot tell whether a study fits you. It can show who was in it, and where the result stops carrying.

Who was studied

No description of who was studied is recorded.

Who is missing from the studies

  • Which groups were under-represented in the studies has not been recorded for this substance. Pregnancy, breastfeeding, children, older adults, and people with liver or kidney conditions are commonly excluded from trials; nothing here says whether they were.

Where the result stopped carrying

  • This is a scope explorer, not a diagnosis engine.
  • It shows who was studied so you can see whether people similar to you were included.

RNAWiki cannot tell whether a study fits you. It can show who was in it.

What it would be like to takeRead from sources, not yet reviewed

Why it might seem to do nothing

A real effect and a noticed effect are different things. These are the recorded reasons the two come apart.

It was studied in different people

The people in the studies were not much like the reader.

On this record: Which groups were under-represented in the studies has not been recorded for this substance. Pregnancy, breastfeeding, children, older adults, and people with liver or kidney conditions are commonly excluded from trials; nothing here says whether they were.

The evidence may simply be wrong

Small early studies often do not hold up.

On this record: RNAWiki has not yet published a reviewed conclusion for this use.

Other reasons RNAWiki checked and found nothing for (11)
It was studied for a different goal
The studies measured something else entirely. Nothing in this record points to this reason.
A different form was studied
The studied form is not the form on the shelf. Nothing in this record points to this reason.
There was nothing to correct
Where a level is already normal, topping it up may change nothing. Nothing in this record points to this reason.
Something else had to happen too
In the studies it was paired with training, a diet or another treatment. Nothing in this record points to this reason.
The change is too small to feel
A real change can still sit below what a person notices. Nothing in this record points to this reason.
Day-to-day swing hides it
Sleep, food, stress and time of day move most numbers more than this would. Nothing in this record points to this reason.
Not enough time yet
The studies ran longer than the person has waited. Nothing in this record points to this reason.
It was not taken as studied
Missed days change the result, and studies count them. Nothing in this record points to this reason.
Something else changed at the same time
Two changes at once cannot be told apart afterwards. Nothing in this record points to this reason.
The product may not be what it says
Contents of a sold product are not always what the label states. Nothing in this record points to this reason.
No recorded reason
RNAWiki has nothing stored that would explain it. Nothing in this record points to this reason.

None of these is a reason to take more. Taking more is not a step this page ever suggests.

What it would be like to takeRead from sources, not yet reviewed

What taking it involves

The recorded facts about getting hold of it and using it. Nothing here is a suggestion about what you should do.

How it is supplied

Varies by country

Quoted from a source

Where this came from

Copied from a source RNAWiki stored, with the source named.

Read from the recorded approval status.

No source is stored against this line.

Form and route

Not recorded.

Nothing recorded

Where this came from

RNAWiki holds nothing here and says so rather than guessing.

No form or route is recorded.

No source is stored against this line.

Who oversees it

Not usually supervised: sold as a supplement or food ingredient where recorded. That is a legal category, not a safety judgement.

Quoted from a source

Where this came from

Copied from a source RNAWiki stored, with the source named.

The identity record classes it as a supplement ingredient; no medicines register records an approval.

No source is stored against this line.

What is in the pack

Not recorded.

Nothing recorded

Where this came from

RNAWiki holds nothing here and says so rather than guessing.

Nothing is recorded about product quality.

No source is stored against this line.

Where it is registered

Regulatory records are listed in the technical disclosure at the foot of this page.

Counted from records

Where this came from

A count of rows RNAWiki holds. It describes our records, not your body.

Register entries are stored per jurisdiction and shown with their dates.

No source is stored against this line.

Why people stop

Not recorded.

Nothing recorded

Where this came from

RNAWiki holds nothing here and says so rather than guessing.

No record of why people stopped taking it is stored for this substance.

No source is stored against this line.

What it would be like to takeNothing found in the sources checked

What can go wrong

Sorted by where each line came from. A regulator's label and a report somebody sent in are not the same kind of fact.

Nothing found in the sources checked

No harm is recorded against this substance in the sources RNAWiki checked. Finding nothing is not the same as showing there is nothing.

The sources listed were searched and held nothing. That is not the same as nothing existing.

Over a long time. No completed tested study window is recorded, so long-term effects are not established by the registry record.

Groups the studies covered thinly. Which groups were under-represented in the studies has not been recorded for this substance. Pregnancy, breastfeeding, children, older adults, and people with liver or kidney conditions are commonly excluded from trials; nothing here says whether they were.

What is missing or unclearRead from sources, not yet reviewed

Does the exact form matter?

Evidence belongs to the exact thing that was tested. A different salt, a different mixture or a different preparation is a different question.

The form that was studied

Not recorded.

Nothing recorded

Where this came from

RNAWiki holds nothing here and says so rather than guessing.

The exact form studied is not recorded.

No source is stored against this line.

What is sold

Not recorded.

Nothing recorded

Where this came from

RNAWiki holds nothing here and says so rather than guessing.

Nothing further is recorded about which forms are sold.

No source is stored against this line.

What is recorded as being sold

  • 146 published labels name it as an active ingredient. 37 of them describe this substance alone, which is where its own label text on this page comes from.

    US prescribing information · 1583cf73-c22c-0fa8-e054-00144ff8d46c · read 2026-08-29

  • Those labels are classed as human otc drug.

    US prescribing information · 1583cf73-c22c-0fa8-e054-00144ff8d46c · read 2026-08-29

Evidence carries across two names for one substance. It does not carry across a salt, a mirror form or a mixture.

What it would be like to takeRead from sources, not yet reviewed

What you could measure

Watching one thing carefully can tell you whether it moved. It cannot tell you what moved it.

This is sold without a prescription, so a person can sensibly watch one thing and see whether it moves.

  1. Pick one goal. One goal only. Two at once cannot be told apart afterwards.

  2. Pick one thing to watch. No registered study lists a measure RNAWiki could read for this.

  3. Measure before you start. Take the same measurement several times first. One reading is not a starting point.

  4. Know the swing. Write down how much it moves on its own across a normal week.

  5. Change one thing. Change nothing else at the same time, including training and sleep.

  6. Give it the study length. No finished study window is recorded, so no length is suggested here.

  7. Track whether you took it. Missed days are the most common reason a home test shows nothing.

  8. Read the trend. Look at the line across weeks. A single reading tells you almost nothing.

What not to measure

  • Anything that swings more day to day than the change you are looking for.
  • A wearable estimate of sleep stages, which is an estimate and not a measurement.
  • Weight on one morning, which mostly records water.
  • A feeling you did not write down before starting.

When to stop

  • Stop if something new and unpleasant starts, and ask a pharmacist or doctor.
  • Stop if you cannot keep everything else steady, because the result will not mean anything.
  • Stop at the end of the window you set, and read the trend then.

Tracking can show whether something changed for you. It cannot show what caused it.

RNAWiki does not work out an amount for anyone.

What is missing or unclearRead from sources, not yet reviewed

What nobody knows yet

Open questions, each with why it is open and what would close it.

How much did people take in the studies?

The sources RNAWiki checked hold nothing for this field.

Why it matters. A result belongs to an amount. Without the amount the result floats free.

What would answer it

A stored source that records it, and a reviewer to sign it off.

Last checked 2026-09-04. Searched: The sources listed in the receipts at the foot of this page.

How fast does the body clear it?

The sources RNAWiki checked hold nothing for this field.

Why it matters. Without this, nothing on this page can say how long anything lasts.

What would answer it

A stored source that records it, and a reviewer to sign it off.

Last checked 2026-09-04. Searched: The sources listed in the receipts at the foot of this page.

Missing populations

Which groups were under-represented in the studies has not been recorded.

Why it matters. Recorded by the evidence model as a gap on this record.

What would answer it

A study that measures it, and a reviewer to sign it off.

Last checked 2026-09-04. Searched: The sources listed in the receipts at the foot of this page.

Missing long-term data

No completed tested study window is recorded.

Why it matters. Recorded by the evidence model as a gap on this record.

What would answer it

A study that measures it, and a reviewer to sign it off.

Last checked 2026-09-04. Searched: The sources listed in the receipts at the foot of this page.

No reviewed conclusion

RNAWiki has not yet published a reviewed conclusion for this use.

Why it matters. Recorded by the evidence model as a gap on this record.

What would answer it

A study that measures it, and a reviewer to sign it off.

Last checked 2026-09-04. Searched: The sources listed in the receipts at the foot of this page.

Missing interaction studies

No interaction was found in the registers checked. Not finding one is not the same as showing there is none.

Why it matters. Recorded by the evidence model as a gap on this record.

What would answer it

A study that measures it, and a reviewer to sign it off.

Last checked 2026-09-04. Searched: The sources listed in the receipts at the foot of this page.

Formulation uncertainty

Several salts, forms or products of Silver Phosphate are recorded. Results from one form may not transfer to another.

Why it matters. Recorded by the evidence model as a gap on this record.

What would answer it

A study that measures it, and a reviewer to sign it off.

Last checked 2026-09-04. Searched: The sources listed in the receipts at the foot of this page.

Mechanism not reviewed

No reviewed mechanism story exists for this substance.

Why it matters. Recorded by the evidence model as a gap on this record.

What would answer it

A study that measures it, and a reviewer to sign it off.

Last checked 2026-09-04. Searched: The sources listed in the receipts at the foot of this page.

What happened in peopleRead from sources, not yet reviewed

Check any of this yourself

Every line above traced back to the study it came from. This is the technical layer, and the vocabulary changes here.

Where else this substance is registered

FDA substance identifier (UNII)
ZL6T4Y1XP8
CAS registry number
7784-09-0
PubChem compound
159913
RxNorm concept
1665220
European Chemicals Agency number
232-049-0

Checks this page had to pass

  • Passed

    Identity resolved

    no open identity hold

  • Passed

    No unresolved merge across substance families

    no quarantine open

  • Passed

    Every public sentence names a source

    The opening statement carries the origin: Quoted from a stored source.

  • Not passed

    Trial roles classified for highlighted evidence

    No registered study is classified as testing this substance.

  • Passed

    No internal keys in reader text

    enforced by the copy-contract test over the rendered page

  • Passed

    Safety mode resolved

    The identity record classes it as a supplement ingredient; no medicines register records an approval.

  • Passed

    Canonical metadata present

    slug and display name present

What is missing or unclearRead from sources, not yet reviewed

What to learn next

Ordered by what would most change how you read this page, starting with what is easiest to misunderstand.

This order is fixed in code and does not count clicks or time on the page.

What is not here

9 questions this page could not answer

These sections were prepared and left out because there was nothing to put in them. They are listed rather than hidden, so the gaps in this record are visible.

  • What was measured, goal by goal — found nothing in the sources checked.
  • The path through the body — found nothing in the sources checked.
  • Felt, measured, or meaningful — found nothing in the sources checked.
  • How long anything takes — found nothing in the sources checked.
  • What it may clash with — found nothing in the sources checked.
  • Other ways to the same goal — found nothing in the sources checked.
  • Claims that go past the evidence — found nothing in the sources checked.
  • How this medicine reached us — found nothing in the sources checked.
  • What changed on this page — found nothing in the sources checked.

The record as stored

The full record, for auditing

Everything above is built from what is below. This layer keeps the technical vocabulary, record identifiers and every stored row, so a reader who wants to check the page can.

Recorded evidence blocks (8)

What did Silver Phosphate's largest trial (3000 people) and its longest (5 months) measure?


3000 people in Silver Phosphate's largest registered study, 5 months in its longest registered window, measuring The Dutch version of the Questionnaire for the assessment of emotion regulation in children and adolescents (FEEL-KJ). ClinicalTrials.gov · 2026-09-01

1 na; NCT04608578; 2021-03-15; no ageing endpoint recorded. Last human test completed 2021, NCT04608578.

Interpretation These counts include studies where Silver Phosphate was a comparison treatment, a background treatment or an exposure in an observational study, and the longest window may be a planned end date. Trial roles have not yet been classified for this record.

Show the evidence
  • na
    1
  • Last recorded human test NCT04608578
    2021-03-15

recorded 2026-09-01 · last checked 2026-09-04

From yeast to human: where has Silver Phosphate shown lifespan?


C. elegans: lifespan, Drosophila: biomarker, yeast: biomarker, mouse: mechanism-only, rat: lifespan, dog: mechanism-only and human: mechanism-only (1): the rungs where Silver Phosphate has a recorded finding. Europe PMC and ClinicalTrials.gov · organism ladder · 2026-09-01

Interpretation The Dutch version of the Questionnaire for the assessment of emotion regulation in children and adolescents (FEEL-KJ) — the recorded outcome words.

Yeast biomarkerC. elegans lifespanDrosophila biomarkerMouse mechanism-onlyRat lifespanDog mechanism-onlyNon-human primate Human mechanism-only
Show the evidence
  • C. elegans
    lifespan
  • Drosophila
    biomarker
  • yeast
    biomarker
  • mouse
    mechanism-only
  • rat
    lifespan
  • dog
    mechanism-only
1 more recorded row
  • human NCT04608578
    mechanism-only; The Dutch version of the Questionnaire for the assessment of emotion regulation in children and adolescents (FEEL-KJ); 1

recorded 2026-09-01 · last checked 2026-09-04

Did Silver Phosphate move DunedinPACE, and by how much?


DunedinPACE: "This prespecified ancillary study evaluated the 2-year effect of a daily MVM (Centrum Silver) and cocoa extract (500 mg cocoa flavanols per day, including 80 mg (-)-epicatechin) on five DNA methylation measures of biological aging (PCHannum, PCHorvath, PCPhenoAge, PCGrimAge and DunedinPACE) among 958 participants (482…" Europe PMC · epigenetic clock search · 2026-03-09

1 recorded sentence; 2026; biomarker

Show the evidence
  • DunedinPACE PMID 41803341
    2026; "This prespecified ancillary study evaluated the 2-year effect of a daily MVM (Centrum Silver) and cocoa extract (500 mg cocoa flavanols per day, including 80 mg (-)-epicatechin) on five DNA methylation measures of biological aging (PCHannum, PCHorvath, PCPhenoAge, PCGrimAge and DunedinPACE) among 958 participants (482 women and 476 men) in the COcoa Supplement and Multivitamin Outcomes Study…"

recorded 2026-03-09 · last checked 2026-09-04

More Silver Phosphate was worse in human: at what point?


Hormetic in human: "In this study, we investigated whether green-synthesized silver nanoparticles (AgNPs) induce hormetic-like, dose-dependent responses in sage (Salvia officinalis L.), integrating germination performance, morphophysiological traits, and secondary metabolite profiling." Europe PMC · dose-response search · 2026-08-01

5 recorded sentences naming Silver Phosphate; hormetic, U-shaped, biphasic

Show the evidence
  • hormetic PMID 42120587
    "In this study, we investigated whether green-synthesized silver nanoparticles (AgNPs) induce hormetic-like, dose-dependent responses in sage (Salvia officinalis L.), integrating germination performance, morphophysiological traits, and secondary metabolite profiling."
  • U-shaped PMID 42554351
    "Together with three half-sandwich rhodium building blocks (B1-B3) of varying conjugation sizes, L1 was assembled via coordination-driven self-assembly and silver-ion bridging to afford one U-shaped and two S-shaped double-metallacycles in high yields."
  • hormetic PMID 40952583
    "This hormetic response exhibited by microalgae upon exposure to silver ions indicates a nonlinear coupling between ionic stress and cellular growth."

biphasic

  • PMID 42231718
    "Comparison with silver ions (Ag<sup>+</sup>) controls indicates that the observed biphasic effects are largely attributable to dissolved Ag<sup>+</sup>."
  • PMID 41632915
    "At high silver concentrations, the coexistence of amorphous nanoclusters and Ag<sub>3</sub>PO<sub>4</sub> is expected to form a biphasic release system that enables both immediate and sustained silver ion release."

recorded 2026-08-01 · last checked 2026-09-04

Which one trial of Silver Phosphate posted no result?


Posted no result
1 of 1 completed trials
Registrations
NCT04608578
Completion dates
oldest 2021-03-15
Show the evidence
  • Trial NCT04608578
    2021-03-15

At the median, Silver Phosphate's trials enrolled 3000 people — anything larger?


Median enrolment
3000
Largest enrolment
3000
Registered trials counted
1

Was Silver Phosphate studied with exercise?


exercise is named in Silver Phosphate's label sentences: "A 70-min silver yoga exercise program was implemented three times per week for 6 months as the intervention for the participants in the experimental group." openfda-label+europepmc · 2008-10-22

1 recorded statement; exercise

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  • exercise
    A 70-min silver yoga exercise program was implemented three times per week for 6 months as the intervention for the participants in the experimental group.

recorded 2008-10-22 · last checked 2026-09-04

What is recorded about Silver Phosphate and autophagy?


"These findings demonstrate that silver(I) and gold(I) NHC complexes induce ROS-dependent autophagic cell death in this kind of cancer cells." — where Silver Phosphate and autophagy appear together. Europe PMC · pathway abstract search · 2026-04-02

autophagy, AMPK; PMID 41896699, 42022757, 40385058, 37517725

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  • autophagy PMID 41896699
    "These findings demonstrate that silver(I) and gold(I) NHC complexes induce ROS-dependent autophagic cell death in this kind of cancer cells."
  • AMPK PMID 42022757
    "Stable cell lines overexpressing AMPK-TurboID were successfully established, and interacting proteins were identified through biotin labeling, silver staining and mass spectrometry analysis."

autophagy

  • PMID 40385058
    "Warm silver needle acupuncture and MTrP intervention effectively alleviate CPP by modulating neutrophil autophagy and inflammatory factors, and their combination yields enhanced therapeutic benefits for women with CPP."
  • PMID 37517725
    "Furthermore, analysis of autophagy inhibition by 3-Methyladenine indicated that the promotion of EMT by silver loading was related to the increased autophagy flux."

recorded 2026-04-02 · last checked 2026-09-04

Where it is registered
Identifiers, relations and other names

The exact record

PubChem CID
159913
CAS number
7784-09-0
RxCUI
1665220
InChIKey
FJOLTQXXWSRAIX-UHFFFAOYSA-K
Trade name
Argentum Phosphoricum
Also called
ARGENTUM PHOSPHORICUM [HPUS], PHOSPHORIC ACID, SILVER(1+) SALT (1:3), SILVER ORTHOPHOSPHATE (AG3PO4), SILVER PHOSPHATE [MI]
Sources (9)

Sources

  • ClinicalTrials.gov ClinicalTrials.gov API v2 snapshot 2026-09-01T09:00:05 ·
  • this record's own fields 2,3,5 ·
  • Europe PMC dose-response search ·
  • Europe PMC epigenetic clock search ·
  • Europe PMC pathway abstract search ·
  • Europe PMC search ·
3 more sources

ClinicalTrials.gov — US Government work · Europe PMC — metadata only, under the recorded legal gate · derived from this page's own recorded fields; no external licence · mixed register set; per-register licences in docs/specs/corpus-20k-sources.md · openFDA / DailyMed — US Government work

How these records are assembled · Which registers were checked

Index-quality checks
  • identity passed: no open identity hold
  • required summary fields resolved: 3 required field(s) not terminal: Best-supported result, Biggest unanswered question, Human evidence
  • public claims reviewed: 0 reviewed claim(s); drafts are never rendered
  • source coverage passed: 9 source rows
  • no critical contamination: no quarantine open
  • canonical metadata passed: slug and display name present
  • no raw internal fields: enforced by the copy-contract test over the rendered page

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