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Mycophenolate Mofetil

  • Prescription medicine
  • Prescription only
  • Identity checked
  • Sources last checked 2026-09-04

This page shows what was measured, who it was measured in, and what that does not settle.

What Mycophenolate Mofetil does in the body

Organ rejection

From the FDA-approved label: Mycophenolate mofetil has been demonstrated in experimental animal models to prolong the survival of allogeneic transplants (kidney, heart, liver, intestine, limb, small bowel, pancreatic islets, and bone marrow). Mycophenolate mofetil has also been shown to reverse ongoing acute rejection in the canine renal and rat cardiac allograft models. Mycophenolate mofetil also inhibited proliferative arteriopathy in experimental models of aortic and cardiac allografts in rats, as well as in primate cardiac xenografts. Mycophenolate mofetil was used alone or in combination with other immunosuppressive agents in these studies.

What happened in people

RNAWiki has not yet published a reviewed conclusion for this use.

A fixed RNAWiki sentence

Where this came from

Wording RNAWiki always uses, not a finding about this substance.

No reviewed claim names a result for any goal on this record.

No source is stored against this line.

The limit that matters most

Not recorded.

Where it acts
Not recorded.
Kind of result
No result is published, so no kind of result applies yet
Supervision
Professional supervision is normally required. A regulator classifies this substance in a way that restricts how it is supplied.

What the registries record it as

  • Its recorded molecular formula is C23H31NO7, weighing 433.50.

    US prescribing information · ce06afcb-4e6c-4b78-8bad-9909c8fffa52 · read 2026-08-30

Where each sentence above came from

No recorded sentence describes the change this makes in a way that stands on its own. The page opens with what it is taken for instead, and the recorded explanation follows below.

Shown as the opening line on this page.

No statement of the main limit is recorded.

The four opening statements run to 105 words.

Words this page uses

Four words worth knowing first

Chosen from what this page shows, with each one explained before the word it depends on.

Biomarker

A biomarker is a number from a test that stands in for something about health.

A picture of it, and where the picture fails

A biomarker is like a fuel gauge.

Where that stops being true. A gauge is wired to the tank. Many biomarkers are only loosely tied to health.

What people get wrong. A better number is read as a better life. Several medicines improved a number and helped nobody.

A measurable indicator used as a substitute for a clinical outcome of interest.

Placebo

A placebo is a dummy treatment given so the real one can be compared with it.

A picture of it, and where the picture fails

A placebo is like a blank control in an experiment.

Where that stops being true. A blank does nothing. People given a placebo often do get better.

What people get wrong. A placebo effect is read as imaginary. The improvement is measured and real.

An inactive intervention matched in appearance to the test intervention, used to control for non-specific effects.

Comparator

A comparator is whatever the treatment was measured against.

A picture of it, and where the picture fails

It is like the other runner in a race.

Where that stops being true. A race has one winner. A study can show both arms improved.

What people get wrong. Results are read without asking what the other group got. Beating nothing is not beating a treatment.

The control condition against which the experimental intervention is assessed.

What happened in peopleRead from sources, not yet reviewed

What happened in people

Each card is one study: the exact question it asked, who was in it, and whether it showed what it set out to show.

Overall survival

The study did not show it

Who was studied
NCT02416388
How many people
3100
Study design
Phase 2/Phase 3
Compared against
Not recorded for this study
Kind of result
Living longer, or avoiding a major event
What was found
Result not recorded on this page
Repeated elsewhere
Unreplicated

What this does not prove. A study that did not show an effect does not show that no effect exists anywhere.

The limits of this study, and where it came from

Main limit. No limitation is recorded for this study.

How far it carries. This study is recorded from the curated record, not from the registry match.

Form and route. Oral

Interval reported. Not recorded in this summary

Written into the record, not signed off as a reviewed claim.

  • openFDA Drugs@FDA · a recorded source, not a stored snapshot
  • openFDA NDC Directory · a recorded source, not a stored snapshot
  • openFDA SPL label · a recorded source, not a stored snapshot
  • PubChem PUG-REST · a recorded source, not a stored snapshot

Measurement of inflammatory cytokines (interleukin (IL) 1 beta, IL-1RA, IL-6, IL-18, tumor necrosis factor (TNF) alpha, CXCL9 and CXCL10) on serum of patients

The study did not show it

Who was studied
NCT05670301
How many people
2500
Study design
Not applicable
Compared against
Not recorded for this study
Kind of result
A number that stands in for health
What was found
Result not recorded on this page
Repeated elsewhere
Unreplicated

What this does not prove. A study that did not show an effect does not show that no effect exists anywhere.

The limits of this study, and where it came from

Main limit. No limitation is recorded for this study.

How far it carries. This study is recorded from the curated record, not from the registry match.

Form and route. Oral

Interval reported. Not recorded in this summary

Written into the record, not signed off as a reviewed claim.

  • openFDA Drugs@FDA · a recorded source, not a stored snapshot
  • openFDA NDC Directory · a recorded source, not a stored snapshot
  • openFDA SPL label · a recorded source, not a stored snapshot
  • PubChem PUG-REST · a recorded source, not a stored snapshot

Incidence of Failure on the Composite of Treated Biopsy-proven Acute Rejection (tBPAR) or Estimated Glomerular Filtration Rate (eGFR) < 50 mL/Min/1.73m2.

The study did not show it

Who was studied
NCT01950819
How many people
2037
Study design
Phase 4
Compared against
Not recorded for this study
Kind of result
A number that stands in for health
What was found
Result not recorded on this page
Repeated elsewhere
Unreplicated

What this does not prove. A study that did not show an effect does not show that no effect exists anywhere.

The limits of this study, and where it came from

Main limit. No limitation is recorded for this study.

How far it carries. This study is recorded from the curated record, not from the registry match.

Form and route. Oral

Interval reported. Not recorded in this summary

Written into the record, not signed off as a reviewed claim.

  • openFDA Drugs@FDA · a recorded source, not a stored snapshot
  • openFDA NDC Directory · a recorded source, not a stored snapshot
  • openFDA SPL label · a recorded source, not a stored snapshot
  • PubChem PUG-REST · a recorded source, not a stored snapshot

Subproject A: Disease safety (flare) in ARD patients immunized with RZV in comparison to non-vaccinated ARD patients (placebo group)

The study did not show it

Who was studied
NCT05879419
How many people
2005
Study design
Phase 4
Compared against
Not recorded for this study
Kind of result
A number that stands in for health
What was found
Result not recorded on this page
Repeated elsewhere
Unreplicated

What this does not prove. A study that did not show an effect does not show that no effect exists anywhere.

The limits of this study, and where it came from

Main limit. No limitation is recorded for this study.

How far it carries. This study is recorded from the curated record, not from the registry match.

Form and route. Oral

Interval reported. Not recorded in this summary

Written into the record, not signed off as a reviewed claim.

  • openFDA Drugs@FDA · a recorded source, not a stored snapshot
  • openFDA NDC Directory · a recorded source, not a stored snapshot
  • openFDA SPL label · a recorded source, not a stored snapshot
  • PubChem PUG-REST · a recorded source, not a stored snapshot

GFR calculated from the serum creatinine with the Cockcroft-Gault formula at 12 months posttransplantation

The study did not show it

Who was studied
NCT00231764
How many people
1760
Study design
Phase 4
Compared against
Not recorded for this study
Kind of result
A number that stands in for health
What was found
Result not recorded on this page
Repeated elsewhere
Unreplicated

What this does not prove. A study that did not show an effect does not show that no effect exists anywhere.

The limits of this study, and where it came from

Main limit. No limitation is recorded for this study.

How far it carries. This study is recorded from the curated record, not from the registry match.

Form and route. Oral

Interval reported. Not recorded in this summary

Written into the record, not signed off as a reviewed claim.

  • openFDA Drugs@FDA · a recorded source, not a stored snapshot
  • openFDA NDC Directory · a recorded source, not a stored snapshot
  • openFDA SPL label · a recorded source, not a stored snapshot
  • PubChem PUG-REST · a recorded source, not a stored snapshot

Efficacy failure rate

The study did not show it

Who was studied
NCT00717470
How many people
1252
Study design
Phase 4
Compared against
Not recorded for this study
Kind of result
A number that stands in for health
What was found
Result not recorded on this page
Repeated elsewhere
Unreplicated

What this does not prove. A study that did not show an effect does not show that no effect exists anywhere.

The limits of this study, and where it came from

Main limit. No limitation is recorded for this study.

How far it carries. This study is recorded from the curated record, not from the registry match.

Form and route. Oral

Interval reported. Not recorded in this summary

Written into the record, not signed off as a reviewed claim.

  • openFDA Drugs@FDA · a recorded source, not a stored snapshot
  • openFDA NDC Directory · a recorded source, not a stored snapshot
  • openFDA SPL label · a recorded source, not a stored snapshot
  • PubChem PUG-REST · a recorded source, not a stored snapshot
What we know
RNAWiki holds 6 written-up human studies for this substance, each with the question it asked.
How we know it
Each card names the study, the number of people and what the study set out to measure.
What this does not prove
These summaries were written by a person and have not been signed off as reviewed claims.
Why it matters
A study that failed is as informative as one that worked, and both are here.
What we still do not know
No reviewed claim exists, so no exact population, effect size or interval is published yet.

What is missing or unclearRead from sources, not yet reviewed

Were people like you studied?

RNAWiki cannot tell whether a study fits you. It can show who was in it, and where the result stops carrying.

Who was studied

People similar to this profile were included.

  • Mycophenolate mofetil for oral suspension is indicated for the prophylaxis of organ rejection, in adult and pediatric recipients 3 months of age and older of allogeneic kidney [see Clinical Studies (14.1) ], heart [see Clinical Studies (14.2) ] or liver transplants [see Clinical Studies (14.3) ], in combination with other immunosuppressants.

Who is missing from the studies

  • Which groups were under-represented in the studies has not been recorded for this substance. Pregnancy, breastfeeding, children, older adults, and people with liver or kidney conditions are commonly excluded from trials; nothing here says whether they were.

What the label states about particular groups

  • On pediatric, the label states: “Safety and effectiveness have been established in pediatric patients 3 months and older for the prophylaxis of organ rejection of allogenic kidney, heart or liver transplants.”

    US prescribing information · ce06afcb-4e6c-4b78-8bad-9909c8fffa52 · read 2026-08-30

  • On older people, the label states: “Clinical studies of mycophenolate mofetil did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects.”

    US prescribing information · ce06afcb-4e6c-4b78-8bad-9909c8fffa52 · read 2026-08-30

  • On people who are pregnant, the label states: “Exposure Registry There is a pregnancy exposure registry that monitors pregnancy outcomes in women exposed to mycophenolate during pregnancy and those becoming pregnant within 6 weeks of discontinuing mycophenolate mofetil treatment.”

    US prescribing information · ce06afcb-4e6c-4b78-8bad-9909c8fffa52 · read 2026-08-30

  • On people who are breastfeeding, the label states: “Risk Summary There are no data on the presence of mycophenolate in human milk, or the effects on milk production.”

    US prescribing information · ce06afcb-4e6c-4b78-8bad-9909c8fffa52 · read 2026-08-30

Where the result stopped carrying

  • This is a scope explorer, not a diagnosis engine.
  • It shows who was studied so you can see whether people similar to you were included.

RNAWiki cannot tell whether a study fits you. It can show who was in it.

What it would be like to takeRead from sources, not yet reviewed

Why it might seem to do nothing

A real effect and a noticed effect are different things. These are the recorded reasons the two come apart.

It was studied in different people

The people in the studies were not much like the reader.

On this record: Which groups were under-represented in the studies has not been recorded for this substance. Pregnancy, breastfeeding, children, older adults, and people with liver or kidney conditions are commonly excluded from trials; nothing here says whether they were.

The evidence may simply be wrong

Small early studies often do not hold up.

On this record: RNAWiki has not yet published a reviewed conclusion for this use.

Other reasons RNAWiki checked and found nothing for (11)
It was studied for a different goal
The studies measured something else entirely. Nothing in this record points to this reason.
A different form was studied
The studied form is not the form on the shelf. Nothing in this record points to this reason.
There was nothing to correct
Where a level is already normal, topping it up may change nothing. Nothing in this record points to this reason.
Something else had to happen too
In the studies it was paired with training, a diet or another treatment. Nothing in this record points to this reason.
The change is too small to feel
A real change can still sit below what a person notices. Nothing in this record points to this reason.
Day-to-day swing hides it
Sleep, food, stress and time of day move most numbers more than this would. Nothing in this record points to this reason.
Not enough time yet
The studies ran longer than the person has waited. Nothing in this record points to this reason.
It was not taken as studied
Missed days change the result, and studies count them. Nothing in this record points to this reason.
Something else changed at the same time
Two changes at once cannot be told apart afterwards. Nothing in this record points to this reason.
The product may not be what it says
Contents of a sold product are not always what the label states. Nothing in this record points to this reason.
No recorded reason
RNAWiki has nothing stored that would explain it. Nothing in this record points to this reason.

None of these is a reason to take more. Taking more is not a step this page ever suggests.

What it would be like to takeRead from sources, not yet reviewed

What taking it involves

The recorded facts about getting hold of it and using it. Nothing here is a suggestion about what you should do.

How it is supplied

Prescription only

Quoted from a source

Where this came from

Copied from a source RNAWiki stored, with the source named.

Read from the recorded approval status.

No source is stored against this line.

Form and route

Oral

Source-linked record

Where this came from

A person wrote this into the record with the study named beside it. No reviewer has signed it off.

The form and route recorded on this substance.

No source is stored against this line.

Who oversees it

Professional supervision is normally required. A regulator classifies this substance in a way that restricts how it is supplied.

Quoted from a source

Where this came from

Copied from a source RNAWiki stored, with the source named.

Suppression classes recorded: S1, S3, S6.

No source is stored against this line.

What is in the pack

Sold as capsule, tablet, injectable, for suspension, given by the oral, injection, intravenous route.

Source-linked record

Where this came from

A person wrote this into the record with the study named beside it. No reviewer has signed it off.

Recorded notes on how this is sold and what that means for what is in the pack.

No source is stored against this line.

Where it is registered

Regulatory records are listed in the technical disclosure at the foot of this page.

Counted from records

Where this came from

A count of rows RNAWiki holds. It describes our records, not your body.

Register entries are stored per jurisdiction and shown with their dates.

No source is stored against this line.

Why people stop

Not recorded.

Nothing recorded

Where this came from

RNAWiki holds nothing here and says so rather than guessing.

No record of why people stopped taking it is stored for this substance.

No source is stored against this line.

What it would be like to takeNothing found in the sources checked

What can go wrong

Sorted by where each line came from. A regulator's label and a report somebody sent in are not the same kind of fact.

Nothing found in the sources checked

No harm is recorded against this substance in the sources RNAWiki checked. Finding nothing is not the same as showing there is nothing.

The sources listed were searched and held nothing. That is not the same as nothing existing.

Over a long time. No completed tested study window is recorded, so long-term effects are not established by the registry record.

Groups the studies covered thinly. Which groups were under-represented in the studies has not been recorded for this substance. Pregnancy, breastfeeding, children, older adults, and people with liver or kidney conditions are commonly excluded from trials; nothing here says whether they were.

What is missing or unclearRead from sources, not yet reviewed

Does the exact form matter?

Evidence belongs to the exact thing that was tested. A different salt, a different mixture or a different preparation is a different question.

The form that was studied

Oral

Source-linked record

Where this came from

A person wrote this into the record with the study named beside it. No reviewer has signed it off.

The form used in the studies cited on this page.

No source is stored against this line.

What is sold

Not recorded.

Nothing recorded

Where this came from

RNAWiki holds nothing here and says so rather than guessing.

Nothing further is recorded about which forms are sold.

No source is stored against this line.

What is recorded as being sold

  • 83 products list this as an active ingredient in the United States drug directory. 83 of them contain it and nothing else.

    FDA National Drug Code directory · 14593-876 · read 2026-08-29

  • They are sold as capsule, injection, injection, powder, lyophilized, for solution, powder, powder, for suspension and suspension, taken intravenous and oral.

    FDA National Drug Code directory · 14593-876 · read 2026-08-29

  • The regulator's established pharmacologic class for it is antimetabolite immunosuppressant [epc].

    FDA National Drug Code directory · 14593-876 · read 2026-08-29

  • 48 published labels name it as an active ingredient. 48 of them describe this substance alone, which is where its own label text on this page comes from.

    US prescribing information · ce06afcb-4e6c-4b78-8bad-9909c8fffa52 · read 2026-08-29

  • Those labels are classed as human prescription drug.

    US prescribing information · ce06afcb-4e6c-4b78-8bad-9909c8fffa52 · read 2026-08-29

  • Mycophenolate mofetil is oral at 3 DOSAGE FORMS AND STRENGTHS Mycophenolate mofetil for tablets are available in the following dosage form and strength: Tablets 500 mg mycophenolate mofetil, pinkish brown colored, capsule shaped, film coated tablet wit…, recorded as fda label in effect 2023-10-01 in the United States.

    US prescribing information · ce06afcb-4e6c-4b78-8bad-9909c8fffa52 · read 2026-08-30

Evidence carries across two names for one substance. It does not carry across a salt, a mirror form or a mixture.

What it would be like to takeRead from sources, not yet reviewed

What you could measure

This one is decided with a clinician, so this section holds questions to ask rather than a plan to run.

Self-experiment planning is not offered for a prescription or clinician-supervised medicine. The questions below are for a clinician or pharmacist.

Questions worth asking

  • Which of the trials of Mycophenolate Mofetil studied people like me?
  • What was measured, and for how long?
  • Was the result a laboratory value or a health outcome?
  • What would we watch for, and when would we stop?

Tracking can show whether something changed for you. It cannot show what caused it.

RNAWiki records evidence. It does not say whether this substance is right for you.

What is missing or unclearRead from sources, not yet reviewed

What nobody knows yet

Open questions, each with why it is open and what would close it.

Missing populations

Which groups were under-represented in the studies has not been recorded.

Why it matters. Recorded by the evidence model as a gap on this record.

What would answer it

A study that measures it, and a reviewer to sign it off.

Last checked 2026-09-04. Searched: The sources listed in the receipts at the foot of this page.

Missing long-term data

No completed tested study window is recorded.

Why it matters. Recorded by the evidence model as a gap on this record.

What would answer it

A study that measures it, and a reviewer to sign it off.

Last checked 2026-09-04. Searched: The sources listed in the receipts at the foot of this page.

No reviewed conclusion

RNAWiki has not yet published a reviewed conclusion for this use.

Why it matters. Recorded by the evidence model as a gap on this record.

What would answer it

A study that measures it, and a reviewer to sign it off.

Last checked 2026-09-04. Searched: The sources listed in the receipts at the foot of this page.

Missing interaction studies

No interaction was found in the registers checked. Not finding one is not the same as showing there is none.

Why it matters. Recorded by the evidence model as a gap on this record.

What would answer it

A study that measures it, and a reviewer to sign it off.

Last checked 2026-09-04. Searched: The sources listed in the receipts at the foot of this page.

Formulation uncertainty

Several salts, forms or products of Mycophenolate Mofetil are recorded. Results from one form may not transfer to another.

Why it matters. Recorded by the evidence model as a gap on this record.

What would answer it

A study that measures it, and a reviewer to sign it off.

Last checked 2026-09-04. Searched: The sources listed in the receipts at the foot of this page.

Mechanism not reviewed

No reviewed mechanism story exists for this substance.

Why it matters. Recorded by the evidence model as a gap on this record.

What would answer it

A study that measures it, and a reviewer to sign it off.

Last checked 2026-09-04. Searched: The sources listed in the receipts at the foot of this page.

What happened in peopleRead from sources, not yet reviewed

Check any of this yourself

Every line above traced back to the study it came from. This is the technical layer, and the vocabulary changes here.

How many documents were read

  • 48 documents were read for this substance.

    RNAWiki source record

  • 47 of them state the same bioavailability, and they agree.

    RNAWiki source record

Where else this substance is registered

FDA substance identifier (UNII)
9242ECW6R0
RxNorm concept
200060

Checks this page had to pass

  • Passed

    Identity resolved

    no open identity hold

  • Passed

    No unresolved merge across substance families

    no quarantine open

  • Passed

    Every public sentence names a source

    The opening statement carries the origin: Written into the record, not signed off.

  • Not passed

    Trial roles classified for highlighted evidence

    No registered study is classified as testing this substance.

  • Passed

    No internal keys in reader text

    enforced by the copy-contract test over the rendered page

  • Passed

    Safety mode resolved

    Suppression classes recorded: S1, S3, S6.

  • Passed

    Canonical metadata present

    slug and display name present

What is missing or unclearRead from sources, not yet reviewed

How this medicine reached us

Kept near the foot of the page. A historical event moves up only when it changes something about this substance today.

  1. Withdrawn in United States, 2019, for "Presence of Particulate Matter; glass fragment observed in one vial of reconstituted product" (openFDA drug enforcement Class I recall)

What the approval register records

  • 56 approved applications cover products containing this substance. The earliest was NDA050722, approved 19950503 to ROCHE PALO.

    Drugs@FDA application register · NDA050722 · read 2026-08-29

  • Marketing status on the register: discontinued, none (tentative approval) and prescription.

    Drugs@FDA application register · NDA050722 · read 2026-08-29

  • The earliest marketing start date recorded for a listed product is 19950503.

    FDA National Drug Code directory · 14593-876 · read 2026-08-29

What is missing or unclearRead from sources, not yet reviewed

What to learn next

Ordered by what would most change how you read this page, starting with what is easiest to misunderstand.

This order is fixed in code and does not count clicks or time on the page.

What is not here

9 questions this page could not answer

These sections were prepared and left out because there was nothing to put in them. They are listed rather than hidden, so the gaps in this record are visible.

  • What was measured, goal by goal — found nothing in the sources checked.
  • How close this is to real life — found nothing in the sources checked.
  • The path through the body — found nothing in the sources checked.
  • Felt, measured, or meaningful — found nothing in the sources checked.
  • How long anything takes — found nothing in the sources checked.
  • What it may clash with — found nothing in the sources checked.
  • Other ways to the same goal — found nothing in the sources checked.
  • Claims that go past the evidence — found nothing in the sources checked.
  • What changed on this page — found nothing in the sources checked.

The record as stored

The full record, for auditing

Everything above is built from what is below. This layer keeps the technical vocabulary, record identifiers and every stored row, so a reader who wants to check the page can.

Recorded evidence blocks (9)

On the Mycophenolate Mofetil label: indicated for what?


"1 INDICATIONS & USAGE Mycophenolate mofetil (MMF) is indicated for the prophylaxis of organ rejection, in adult and pediatric recipients 3 months of age and older of allogeneic kidney [see Clinical Studies ( 14.1 )], heart [see Clinical Studies ( 14.2 )] or liver transplants [see Clinical Studies ( 14.3 )] , in…": indications and usage on Mycophenolate Mofetil's label. DailyMed label · fbbe6521-0e21-5372-e053-6394a90ae5e4 · 2026-08-25

738 registered trials of Mycophenolate Mofetil — at which phases?


Registered studies posting no result
440 of 738

738 registered studies of Mycophenolate Mofetil: 359 phase2, 123 phase1, 123 phase4, 110 phase3, 53 na, 28 na or unstated, 9 early phase1. CLINICALTRIALS_SNAPSHOT · 2026-09-01

1660 with a PubMed record

Show the evidence
  • phase2
    359
  • phase1
    123
  • phase4
    123
  • phase3
    110
  • na
    53
  • na or unstated
    28
11 more recorded rows
  • early phase1
    9
  • completed
    418
  • terminated
    108
  • unknown
    67
  • recruiting
    60
  • withdrawn
    34
  • active not recruiting
    33
  • not yet recruiting
    13
  • enrolling by invitation
    2
  • no longer available
    2
  • suspended
    1

recorded 2026-09-01 · last checked 2026-09-04

126 of Mycophenolate Mofetil's trials stopped: safety, futility/efficacy, accrual/recruitment, funding/business, sponsor decision unspecified, other?


safety (13), futility/efficacy (8), accrual/recruitment (56), funding/business (17), sponsor decision unspecified (2) and other (30): Mycophenolate Mofetil's stop wording, clustered. CLINICALTRIALS_SNAPSHOT · 2026-09-01

"Poor accrual and difficulty with multicenter logistics"; 126 of 738 registered studies

Show the evidence

Trial

  • NCT00041288
    terminated; "Poor accrual and difficulty with multicenter logistics"
  • NCT00053014
    terminated; "Poor accrual"
  • NCT00057954
    terminated; "Slow accrual"
  • NCT00085449
    withdrawn; "Funding cut, no patients enrolled"
  • NCT00089141
    terminated; "Low probability of positive outcome"
  • NCT00119366
    terminated; "Funding ended before target accrual was reached; participants are no longer being examined or receiving intervention."
14 further recorded trials
  • NCT00133172
    terminated; "Varience of supply chain from that required by protocol"
  • NCT00151632
    terminated; "insufficient enrollment"
  • NCT00166712
    terminated; "Study stopped due to lack of efficacy \& funding."
  • NCT00203281
    withdrawn; "funding withdrawn"
  • NCT00217152
    terminated; "Roche decided to prematurely terminate study."
  • NCT00230035
    withdrawn; "Recommended by DSMB due to lack of accrual"
  • NCT00243009
    terminated; "Due to a lack of a referal base, study was terminated."
  • NCT00255684
    terminated; "low accrual"
  • NCT00282412
    terminated; "No participant enrolled for three years. No plan to continue study."
  • NCT00290628
    terminated; "Replaced with another study"
  • NCT00303719
    terminated; "IRB Study Closure"
  • NCT00311311
    terminated; "See termination reason in detailed description."
  • NCT00318474
    terminated; "DSMB recommended stopping the trial because of lack of effect."
  • NCT00354172
    terminated; "Competing study was started."

recorded 2026-09-01 · last checked 2026-09-04

Human studies of Mycophenolate Mofetil used Mycophenolate Mofetil 250mg — over how long?


studies of Mycophenolate Mofetil used the recorded amount. ClinicalTrials.gov · 2026-09-01

4 recorded entries; human; also "Mycophenolate Mofetil 250mg", "Mycophenolate Mofetil Capsule 250 mg", "Mycophenolate Mofetil 500mg"

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human

  • NCT00899847
    Mycophenolate Mofetil 250mg
  • NCT01080417
    Mycophenolate Mofetil Capsule 250 mg
  • NCT01842269
    Mycophenolate Mofetil 500mg
  • NCT06068179
    Mycophenolate Mofetil, Oral, 250 Mg

recorded 2026-09-01 · last checked 2026-09-04

Which running trial of Mycophenolate Mofetil could settle lifespan?


NCT06789315 measures To compare the efficacy of MMF versus steroid therapy in improving short-term (28 day) survival outcomes in patients with alcoholic hepatitis, reading out 2026-01-31.

28 open trials; n 60; "Randomized Controlled Trial of Mycophenolate Mofetil Versus Steroid Therapy in Alcoholic Hepatitis"

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Trial

  • NCT06789315
    "Randomized Controlled Trial of Mycophenolate Mofetil Versus Steroid Therapy in Alcoholic Hepatitis"; n 60; "To compare the efficacy of MMF versus steroid therapy in improving short-term (28 day) survival outcomes in patients with alcoholic hepatitis"; 2026-01-31
  • NCT04547049
    "A Study Comparing Haploidentical Hematopoietic Stem Cell Transplantations (HSCTs) From Young Non-first-degree and Older First-degree Donors in Hematological Malignancies"; n 232; "Overall survival (OS)"; 2026-04-01
  • NCT05622318
    "De-escalated Cyclophosphamide (PTCy) and Ruxolitinib for Graft-versus-Host Disease (GVHD) Prophylaxis"; n 56; "The number of subjects who experience GVHD-free survival."; 2026-09
  • NCT04187105
    "BMT-06: Study of Intensity Modulated Total Marrow Irradiation (IM-TMI)"; n 27; "Rate of 1 year Graft-Versus-Host Disease (GVHD) free, relapse free survival (GRFS) survival"; 2026-12
  • NCT04904588
    "HLA-Mismatched Unrelated Donor Hematopoietic Cell Transplantation With Post-Transplantation Cyclophosphamide"; n 300; "Overall Survival"; 2026-12
  • NCT04644016
    "Cord Blood Transplant in Children and Young Adults With Blood Cancers and Non-malignant Disorders"; n 31; "Treatment related mortality at 1 year after myeloablative cord transplant"; 2026-12-20
14 further recorded trials
  • NCT06001385
    "HLA-Mismatched Unrelated Donor Peripheral Blood Stem Cell Transplantation With Reduced Dose Post Transplantation Cyclophosphamide GvHD Prophylaxis"; n 313; "Infection Free Survival"; 2026-12-30
  • NCT05736419
    "A Study of Immune Suppression Treatment for People With Sickle Cell Disease or β-Thalassemia Who Are Going to Receive an Allogeneic Hematopoietic Cell Transplantation (HCT)"; n 24; "Number of participants with treatment related mortality/TRM or primary graft failure"; 2027-02-09
  • NCT02081755
    "Safety and Efficacy of Everolimus Treatment in Liver Transplantation for Liver Cancer"; n 336; "Disease free survival (DFS) defined as the time from randomization to the time of tumor recurrence or death, whichever occurs first."; 2027-03
  • NCT05303727
    "Allogeneic Hematopoietic Stem Cell Transplantation for 4/M Neuroblastoma"; n 64; "overall survival(OS) at 3 year"; 2027-08
  • NCT04888741
    "Methods of T Cell Depletion Trial (MoTD)"; n 400; "GVHD-free, relapse-free survival"; 2027-08-23
  • NCT02558452
    "European Transplant Registry of Senior Renal Transplant Recipients on Advagraf"; n 1000; "Patient survival"; 2028-01
  • NCT02782546
    "Cytokine Induced Memory-like NK Cell Adoptive Therapy After Haploidentical Donor Hematopoietic Cell Transplantation"; n 60; "Kaplan-Meier Estimate of Leukemia-free Survival Rate (LFS)"; 2028-02-13
  • NCT05088356
    "Reduced Intensity Allogeneic HCT in Advanced Hematologic Malignancies w/T-Cell Depleted Graft"; n 66; "Determine the GVHD-free relapse-free survival (GRFS) post-HCT ( Arm-A)"; 2028-05
  • NCT00882895
    "Tandem Stem Cell Transplantation for Non-Hodgkin's Lymphoma"; n 18; "Determine the event free survival"; 2028-06-01
  • NCT07634536
    "Automated Total Marrow and Lymphoid Irradiation for Allogeneic Hematopoietic Cell Transplant"; n 30; "Non-Relapse Mortality (NRM)"; 2028-08
  • NCT02861417
    "Busulfan, Fludarabine Phosphate, and Post-Transplant Cyclophosphamide in Treating Patients With Blood Cancer Undergoing Donor Stem Cell Transplant"; n 204; "Non-relapse mortality rate"; 2028-08-31
  • NCT06680661
    "ABBA CORD: dCBT w/ Abatacept for aGVHD Prophylaxis"; n 20; "Severe aGVHD free survival"; 2028-10-31
  • NCT07359859
    "A Study of Ruxolitinib for Preventing Graft-Versus-Host Disease in People With a Hematologic Malignancy Who Will Receive a Stem Cell Transplant"; n 40; "assess cGVHD-free survival"; 2029-01
  • NCT07566377
    "Cord Blood Transplantation in Children and Young Adults With Blood Cancer"; n 71; "Disease-free Survival (DFS)"; 2030-04-28

Which 177 trials of Mycophenolate Mofetil posted no result?


Posted no result
177 of 177 completed trials
Registrations
NCT00006350, NCT00005935, NCT00003196, NCT00003572, NCT00008151 and NCT00149929, and 171 more
Completion dates
oldest 2001-11; newest 2024-08-19
Show the evidence

Trial

  • NCT00006350
    2001-11
  • NCT00005935
    2002-03
  • NCT00003196
    2002-04
  • NCT00003572
    2002-04
  • NCT00008151
    2002-07
  • NCT00149929
    2003-04
14 further recorded trials
  • NCT00006233
    2003-12
  • NCT00149864
    2003-12
  • NCT00693524
    2004-03
  • NCT00001764
    2004-06
  • NCT00004567
    2004-06
  • NCT00027547
    2004-07
  • NCT00693381
    2004-08
  • NCT00027820
    2004-09-05
  • NCT00187915
    2004-12
  • NCT00261820
    2005-01
  • NCT00005941
    2005-06
  • NCT00812123
    2005-07
  • NCT00893542
    2005-11
  • NCT00893919
    2005-11

At the median, Mycophenolate Mofetil's trials enrolled 45.5 people — anything larger?


Median enrolment
45.5
Largest enrolment
2000
Registered trials counted
728

What do 9912 spontaneous reports say about Mycophenolate Mofetil — and not say?


These are reports people sent to a regulator. They do not show the medicine caused the reaction. Nobody counted how many people took the medicine and reported nothing. The same event can be reported more than once, and many reports are incomplete. News coverage, lawsuits and new warnings change how often people report. A count is not a rate and not a risk.

Mycophenolate Mofetil appears in spontaneous reports to regulators. Across the 10 most-reported reaction terms, 9912 reaction mentions were counted: transplant rejection 1766; cytomegalovirus infection 1746; leukopenia 983; renal impairment 873. FAERS via Open Targets · CHEMBL1200955 · 2026-06-24

Show the evidence
  • transplant rejection
    1766
  • cytomegalovirus infection
    1746
  • leukopenia
    983
  • renal impairment
    873
  • covid-19
    852
  • post transplant lymphoproliferative disorder
    816
4 more recorded rows
  • treatment failure
    797
  • kidney transplant rejection
    726
  • polyomavirus-associated nephropathy
    714
  • transplant dysfunction
    639

recorded 2026-06-24 · last checked 2026-09-04

Which 10 reactions does Mycophenolate Mofetil's label not list?


covid-19, cytomegalovirus infection and kidney transplant rejection and 7 more reported for Mycophenolate Mofetil, absent from its label. FAERS via Open Targets · CHEMBL1200955 · 2026-06-24

2 label terms; 10 reported and unlisted; fbbe6521-0e21-5372-e053-6394a90ae5e4

Show the evidence
  • covid-19
    count not stated
  • cytomegalovirus infection
    count not stated
  • kidney transplant rejection
    count not stated
  • leukopenia
    count not stated
  • polyomavirus-associated nephropathy
    count not stated
  • post transplant lymphoproliferative disorder
    count not stated
4 more recorded rows
  • renal impairment
    count not stated
  • transplant dysfunction
    count not stated
  • transplant rejection
    count not stated
  • treatment failure
    count not stated

recorded 2026-06-24 · last checked 2026-09-04

Where it is registered

Where it’s registered

Withdrawn in United States, 2019, for "Presence of Particulate Matter; glass fragment observed in one vial of reconstituted product" (openFDA drug enforcement Class I recall)

Identifiers, relations and other names

The exact record

ChEMBL id
CHEMBL1200955
PubChem CID
6441022
CAS number
116680-01-4
RxCUI
237112
InChIKey
RTGDFNSFWBGLEC-SYZQJQIISA-N
Also called
MYCOPHENOLATE MOFETIL HYDROCHLORIDE, Myclausen, Mycophenolic acid 2-(4-morpholinyl)ethyl ester, Mycophenylate mofetil, Myhibbin, ec-mps, mmf, mpa, mpm, my-rept, mycophenolate, mycophenolatmofetile
Salt form
Cellcept hydrochloride, Mycophenolate mofetil hcl, mycophenolate sodium, Mycophenolate Mofetil Hydrochloride / Cellcept / Myhibbin
Development code
RS-61443-190, NSC-724229, NSC-758905, RS-61443
Trade name
Arzip, Cellcept, Mycophenolate mofetil teva, Myfenax
Sources (7)

Sources

1 more source

ChEMBL 37 — CC BY-SA 3.0 Unported · ClinicalTrials.gov — US Government work · Open Targets 26.06 — CC0 · mixed register set; per-register licences in docs/specs/corpus-20k-sources.md · openFDA / DailyMed — US Government work · openFDA enforcement — US Government work

How these records are assembled · Which registers were checked

Index-quality checks
  • identity passed: no open identity hold
  • required summary fields resolved: 4 required field(s) not terminal: Why people use it, Best-supported result, Biggest unanswered question, Human evidence
  • public claims reviewed: 0 reviewed claim(s); drafts are never rendered
  • source coverage passed: 7 source rows
  • no critical contamination: no quarantine open
  • canonical metadata passed: slug and display name present
  • no raw internal fields: enforced by the copy-contract test over the rendered page

This is a record of evidence. It is not medical advice, and it does not say this substance suits you. Nothing here says any substance on RNAWiki is appropriate for a child.