The use the label states, quoted from it. No plain-language version of this sentence has been written.
The use the label states, quoted from it. It is written for a clinician, not for a reader without medical training.
No statement of the main limit is recorded.
The four opening statements run to 25 words.
Words this page uses
Four words worth knowing first
Chosen from what this page shows, with each one explained before the word it depends on.
Formulation
A formulation is the exact made-up form a substance comes in.
A picture of it, and where the picture fails
It is like the difference between a whole bean and instant coffee.
Where that stops being true. Coffee tastes different. A formulation can change how much reaches the blood.
What people get wrong. Two products with the same name are assumed to behave the same. They often do not.
The specific composition and physical form of a product, including salt, excipients and release profile.
What happened in people◇Read from sources, not yet reviewed
What happened in people
Each card is one study: the exact question it asked, who was in it, and whether it showed what it set out to show.
Total Number of Participants Randomized Within Each Appendix
✗ The study did not show it
Who was studied
NCT04885530
How many people
10956
Study design
Phase 3
Compared against
Not recorded for this study
Kind of result
A number that stands in for health
What was found
Result not recorded on this page
Repeated elsewhere
Unreplicated
What this does not prove. A study that did not show an effect does not show that no effect exists anywhere.
The limits of this study, and where it came from
Main limit. No limitation is recorded for this study.
How far it carries. This study is recorded from the curated record, not from the registry match.
Form and route.
Interval reported. Not recorded in this summary
Written into the record, not signed off as a reviewed claim.
openFDA Drugs@FDA · a recorded source, not a stored snapshot
openFDA NDC Directory · a recorded source, not a stored snapshot
openFDA SPL label · a recorded source, not a stored snapshot
NIH Dietary Supplement Label Database · a recorded source, not a stored snapshot
Number of HF hospitalizations and/or CV mortality in heart failure patients.
✗ The study did not show it
Who was studied
NCT07543562
How many people
4326
Study design
Phase 3
Compared against
Not recorded for this study
Kind of result
Living longer, or avoiding a major event
What was found
Result not recorded on this page
Repeated elsewhere
Unreplicated
What this does not prove. A study that did not show an effect does not show that no effect exists anywhere.
The limits of this study, and where it came from
Main limit. No limitation is recorded for this study.
How far it carries. This study is recorded from the curated record, not from the registry match.
Form and route.
Interval reported. Not recorded in this summary
Written into the record, not signed off as a reviewed claim.
openFDA Drugs@FDA · a recorded source, not a stored snapshot
openFDA NDC Directory · a recorded source, not a stored snapshot
openFDA SPL label · a recorded source, not a stored snapshot
NIH Dietary Supplement Label Database · a recorded source, not a stored snapshot
Time to Sustained Recovery in Days
✗ The study did not show it
Who was studied
NCT06042855
How many people
3214
Study design
Phase 3
Compared against
Not recorded for this study
Kind of result
A number that stands in for health
What was found
Result not recorded on this page
Repeated elsewhere
Unreplicated
What this does not prove. A study that did not show an effect does not show that no effect exists anywhere.
The limits of this study, and where it came from
Main limit. No limitation is recorded for this study.
How far it carries. This study is recorded from the curated record, not from the registry match.
Form and route.
Interval reported. Not recorded in this summary
Written into the record, not signed off as a reviewed claim.
openFDA Drugs@FDA · a recorded source, not a stored snapshot
openFDA NDC Directory · a recorded source, not a stored snapshot
openFDA SPL label · a recorded source, not a stored snapshot
NIH Dietary Supplement Label Database · a recorded source, not a stored snapshot
Number of Responders and Non-responders Based on the Chronic Obstructive Pulmonary Disease Assessment Test (CAT) at Week 24 and Number of Participants With Imputed CAT Score at Week 24
✗ The study did not show it
Who was studied
NCT03467425
How many people
3109
Study design
Phase 4
Compared against
Not recorded for this study
Kind of result
A number that stands in for health
What was found
Result not recorded on this page
Repeated elsewhere
Unreplicated
What this does not prove. A study that did not show an effect does not show that no effect exists anywhere.
The limits of this study, and where it came from
Main limit. No limitation is recorded for this study.
How far it carries. This study is recorded from the curated record, not from the registry match.
Form and route.
Interval reported. Not recorded in this summary
Written into the record, not signed off as a reviewed claim.
openFDA Drugs@FDA · a recorded source, not a stored snapshot
openFDA NDC Directory · a recorded source, not a stored snapshot
openFDA SPL label · a recorded source, not a stored snapshot
NIH Dietary Supplement Label Database · a recorded source, not a stored snapshot
Change From Baseline in Trough Forced Expiratory Volume in One Second (FEV1) at Week 24
✗ The study did not show it
Who was studied
NCT03034915
How many people
2696
Study design
Phase 4
Compared against
Not recorded for this study
Kind of result
A number that stands in for health
What was found
Result not recorded on this page
Repeated elsewhere
Unreplicated
What this does not prove. A study that did not show an effect does not show that no effect exists anywhere.
The limits of this study, and where it came from
Main limit. No limitation is recorded for this study.
How far it carries. This study is recorded from the curated record, not from the registry match.
Form and route.
Interval reported. Not recorded in this summary
Written into the record, not signed off as a reviewed claim.
openFDA Drugs@FDA · a recorded source, not a stored snapshot
openFDA NDC Directory · a recorded source, not a stored snapshot
openFDA SPL label · a recorded source, not a stored snapshot
NIH Dietary Supplement Label Database · a recorded source, not a stored snapshot
Change From Baseline in Trough Forced Expiratory Volume in One Second (FEV1) at Week 24
✗ The study did not show it
Who was studied
NCT02345161
How many people
1811
Study design
Phase 3
Compared against
Not recorded for this study
Kind of result
A number that stands in for health
What was found
Result not recorded on this page
Repeated elsewhere
Unreplicated
What this does not prove. A study that did not show an effect does not show that no effect exists anywhere.
The limits of this study, and where it came from
Main limit. No limitation is recorded for this study.
How far it carries. This study is recorded from the curated record, not from the registry match.
Form and route.
Interval reported. Not recorded in this summary
Written into the record, not signed off as a reviewed claim.
openFDA Drugs@FDA · a recorded source, not a stored snapshot
openFDA NDC Directory · a recorded source, not a stored snapshot
openFDA SPL label · a recorded source, not a stored snapshot
NIH Dietary Supplement Label Database · a recorded source, not a stored snapshot
What we know
RNAWiki holds 6 written-up human studies for this substance, each with the question it asked.
How we know it
Each card names the study, the number of people and what the study set out to measure.
What this does not prove
These summaries were written by a person and have not been signed off as reviewed claims.
Why it matters
A study that failed is as informative as one that worked, and both are here.
What we still do not know
No reviewed claim exists, so no exact population, effect size or interval is published yet.
What is missing or unclear◇Read from sources, not yet reviewed
Were people like you studied?
RNAWiki cannot tell whether a study fits you. It can show who was in it, and where the result stops carrying.
Who was studied
People similar to this profile were included.
Temporarily relieves occasional sleeplessness, dry and hard stools, and menstrual cramps. Label footnote: Claims based on traditional homeopathic practice, not accepted medical evidence. Not FDA evaluated. This product is not intended to diagnose, treat, cure, or prevent any disease.
Who is missing from the studies
Which groups were under-represented in the studies has not been recorded for this substance. Pregnancy, breastfeeding, children, older adults, and people with liver or kidney conditions are commonly excluded from trials; nothing here says whether they were.
Where the result stopped carrying
This is a scope explorer, not a diagnosis engine.
It shows who was studied so you can see whether people similar to you were included.
RNAWiki cannot tell whether a study fits you. It can show who was in it.
What it would be like to take◇Read from sources, not yet reviewed
Why it might seem to do nothing
A real effect and a noticed effect are different things. These are the recorded reasons the two come apart.
It was studied in different people
The people in the studies were not much like the reader.
On this record: Which groups were under-represented in the studies has not been recorded for this substance. Pregnancy, breastfeeding, children, older adults, and people with liver or kidney conditions are commonly excluded from trials; nothing here says whether they were.
A different form was studied
The studied form is not the form on the shelf.
On this record: This record is linked to 1 related forms. Evidence does not carry across all of them.
The evidence may simply be wrong
Small early studies often do not hold up.
On this record: RNAWiki has not yet published a reviewed conclusion for this use.
Other reasons RNAWiki checked and found nothing for (10)
It was studied for a different goal
The studies measured something else entirely. Nothing in this record points to this reason.
There was nothing to correct
Where a level is already normal, topping it up may change nothing. Nothing in this record points to this reason.
Something else had to happen too
In the studies it was paired with training, a diet or another treatment. Nothing in this record points to this reason.
The change is too small to feel
A real change can still sit below what a person notices. Nothing in this record points to this reason.
Day-to-day swing hides it
Sleep, food, stress and time of day move most numbers more than this would. Nothing in this record points to this reason.
Not enough time yet
The studies ran longer than the person has waited. Nothing in this record points to this reason.
It was not taken as studied
Missed days change the result, and studies count them. Nothing in this record points to this reason.
Something else changed at the same time
Two changes at once cannot be told apart afterwards. Nothing in this record points to this reason.
The product may not be what it says
Contents of a sold product are not always what the label states. Nothing in this record points to this reason.
No recorded reason
RNAWiki has nothing stored that would explain it. Nothing in this record points to this reason.
None of these is a reason to take more. Taking more is not a step this page ever suggests.
What it would be like to take◇Read from sources, not yet reviewed
What taking it involves
The recorded facts about getting hold of it and using it. Nothing here is a suggestion about what you should do.
How it is supplied
Prescription only
❝ Quoted from a source
Where this came from
Copied from a source RNAWiki stored, with the source named.
Read from the recorded approval status.
No source is stored against this line.
Form and route
Not recorded.
∅ Nothing recorded
Where this came from
RNAWiki holds nothing here and says so rather than guessing.
No form or route is recorded.
No source is stored against this line.
Who oversees it
Not usually supervised: sold as a supplement or food ingredient where recorded. That is a legal category, not a safety judgement.
❝ Quoted from a source
Where this came from
Copied from a source RNAWiki stored, with the source named.
The identity record classes it as a supplement ingredient; no medicines register records an approval.
No source is stored against this line.
What is in the pack
Not recorded.
∅ Nothing recorded
Where this came from
RNAWiki holds nothing here and says so rather than guessing.
Nothing is recorded about product quality.
No source is stored against this line.
Where it is registered
Regulatory records are listed in the technical disclosure at the foot of this page.
# Counted from records
Where this came from
A count of rows RNAWiki holds. It describes our records, not your body.
Register entries are stored per jurisdiction and shown with their dates.
No source is stored against this line.
Why people stop
Not recorded.
∅ Nothing recorded
Where this came from
RNAWiki holds nothing here and says so rather than guessing.
No record of why people stopped taking it is stored for this substance.
No source is stored against this line.
What it would be like to take∅Nothing found in the sources checked
What can go wrong
Sorted by where each line came from. A regulator's label and a report somebody sent in are not the same kind of fact.
∅Nothing found in the sources checked
No harm is recorded against this substance in the sources RNAWiki checked. Finding nothing is not the same as showing there is nothing.
The sources listed were searched and held nothing. That is not the same as nothing existing.
Over a long time. No completed tested study window is recorded, so long-term effects are not established by the registry record.
Groups the studies covered thinly. Which groups were under-represented in the studies has not been recorded for this substance. Pregnancy, breastfeeding, children, older adults, and people with liver or kidney conditions are commonly excluded from trials; nothing here says whether they were.
What is missing or unclear◇Read from sources, not yet reviewed
Does the exact form matter?
Evidence belongs to the exact thing that was tested. A different salt, a different mixture or a different preparation is a different question.
The form that was studied
Not recorded.
∅ Nothing recorded
Where this came from
RNAWiki holds nothing here and says so rather than guessing.
The exact form studied is not recorded.
No source is stored against this line.
What is sold
Not recorded.
∅ Nothing recorded
Where this came from
RNAWiki holds nothing here and says so rather than guessing.
Nothing further is recorded about which forms are sold.
No source is stored against this line.
What is recorded as being sold
38873 marketed supplement labels list this ingredient, classed as mineral, other combinations and other.
Those labels carry all other, nutrient and structure/function claims. A claim of that kind is written by the manufacturer and is not assessed by any regulator, so its presence says nothing about whether it is true.
This order is fixed in code and does not count clicks or time on the page.
What is not here
10 questions this page could not answer
These sections were prepared and left out because there was nothing to put in them. They are listed rather than hidden, so the gaps in this record are visible.
What was measured, goal by goal — found nothing in the sources checked.
How close this is to real life — found nothing in the sources checked.
The path through the body — found nothing in the sources checked.
Felt, measured, or meaningful — found nothing in the sources checked.
How long anything takes — found nothing in the sources checked.
What it may clash with — found nothing in the sources checked.
Other ways to the same goal — found nothing in the sources checked.
Claims that go past the evidence — found nothing in the sources checked.
How this medicine reached us — found nothing in the sources checked.
What changed on this page — found nothing in the sources checked.
The record as stored
The full record, for auditing
Everything above is built from what is below. This layer keeps the technical vocabulary, record identifiers and every stored row, so a reader who wants to check the page can.
Recorded evidence blocks (8)
Q1
On the Magnesium Stearate label: indicated for what?
"Sodium sulfate, potassium sulfate, and magnesium sulfate oral solution is indicated for cleansing of the colon as a preparation for colonoscopy in adult patients. Pediatric use information is approved for Braintree Laboratories, Inc.'s SUPREP BOWEL PREP KIT (sodium sulfate, potassium sulfate, and magnesium sulfate)…": indications and usage on Magnesium Stearate's label. DailyMed label · 31d13799-0931-7735-e063-6294a90a6d02 · 2026-06-30
Q2
388 registered trials of Magnesium Stearate — at which phases?
Registered studies posting no result
355 of 388
388 registered studies of Magnesium Stearate: 133 na, 87 phase4, 82 phase3, 71 phase2, 32 phase1, 16 na or unstated, 5 early phase1. CLINICALTRIALS_SNAPSHOT · 2026-09-01
safety (2), futility/efficacy (1), accrual/recruitment (9), funding/business (3) and other (12): Magnesium Stearate's stop wording, clustered. CLINICALTRIALS_SNAPSHOT · 2026-09-01
"Funding completed"; 27 of 388 registered studies
Show the evidence
Trial
NCT00116623
terminated; "Funding completed"
NCT00306462
terminated; "No enrollment in past year, lack of interest"
NCT00463736
terminated; "enrollment proceeding too slowly"
NCT00998738
terminated; "lack of accrual"
NCT01074918
withdrawn; "none enrolled per PI"
NCT01261702
terminated; "not include patient anymore"
14 further recorded trials
NCT01333488
terminated; "Low accrual"
NCT01426165
terminated; "Issues with recruitment. PI decided to terminate study"
NCT01502761
terminated; "No safety issues. Low enrollment secondary to negative stroke studies 2013"
NCT01627353
terminated; "Funding withdrawn"
NCT01794247
terminated; "low recruitment rate"
NCT02453373
terminated; "The study has achieved its objectives of showing feasibility, safety, and trend for improved mRS. FDA and LRS agreed that this study should be terminated, and that a new, PIVOTAL trial should be started."
NCT02498496
withdrawn; "financing delays"
NCT02521753
terminated; "It was not possible to continue recruiting due to SARSCov2 pandemia. Results obtained at that time were already published"
NCT02523911
withdrawn; "investigator graduated and is not longer at this institution"
NCT02680626
terminated; "Pfannenstiel hysterectomies are now rarely performed so cannot recruit eligible patients"
NCT03206008
terminated; "hard to get an informed concent because of small number of indiaiton of surgery"
NCT03253224
terminated; "Because the principle investigator will participate a visiting scholar program for one year in other country, this study has been terminated."
NCT03439358
suspended; "Could not recruit patients"
NCT03749590
terminated; "The design of the MagPEP trial is no longer in compliance with the current state of science."
recorded 2026-09-01 · last checked 2026-09-04
Q4
Human studies of Magnesium Stearate used Magnesium 400Mg — over how long?
Human studies of Magnesium Stearate used "Magnesium 400Mg". ClinicalTrials.gov · 2026-09-01
20 recorded entries; human; infusion; also "Magnesium sulfate 50%", "Composition - Magnesium Lactate 470mg, Pyridoxine HCl 5mg", "50% magnesium sulphate"
Magnesium Sulfate Injection 50% Baxter. Number 5430
NCT03088852
Magnesium Citrate 100 MG
14 more recorded rows
humanNCT03208452
10% magnesium sulfate
humanNCT03344679
Magnesium Sulphate 500 mg
humanNCT03781895
Magnesium Stearate (3mg)
humanNCT03846284
Magnesium sulfate 50mg
humanNCT03846284
Magnesium sulfate 30 mg
humanNCT03879707
Magnesium 500Mg Oral Tablet
humanNCT04249804
Magnesium Sulfate 1000 MG
humanNCT04554862
magnesium 10%
humanNCT05164627
infusion; patients will receive Magnesium infusion (10 mg/kg/hr) from the start of the surgery till the end of it.
humanNCT05904808
Oral Magnesium citrate 600mg
humanNCT06376916
Magnesium Sulfate 2 G
humanNCT06376916
Magnesium Sulfate 2 gram/50ml 0.9% NaCl
humanNCT06376916
Magnesium Sulfate 4 G
humanNCT06376916
Magnesium Sulfate 4g/50ml 0.9% NaCl
recorded 2026-09-01 · last checked 2026-09-04
Q5
Magnesium Stearate's half-life is 17 hours — which schedules were studied?
17 hours, the half-life Magnesium Stearate's label states: "Absorption and Elimination After administration of sodium sulfate, potassium sulfate, and magnesium sulfate oral solution in six healthy subjects, the time at which serum sulfate reached its highest point (T max ) was approximately 17 hours after the first dose or approximately 5 hours after the second dose, and then…" DailyMed label · 31d13799-0931-7735-e063-6294a90a6d02 · 2026-06-30
tmax 17 hours.
Show the evidence
half lifepharmacokinetics
17 hours; Absorption and Elimination After administration of sodium sulfate, potassium sulfate, and magnesium sulfate oral solution in six healthy subjects, the time at which serum sulfate reached its highest point (T max ) was approximately 17 hours after the first dose or approximately 5 hours after the second dose, and then declined with a half-life of 8.5 hours.
tmaxpharmacokinetics
17 hours; Absorption and Elimination After administration of sodium sulfate, potassium sulfate, and magnesium sulfate oral solution in six healthy subjects, the time at which serum sulfate reached its highest point (T max ) was approximately 17 hours after the first dose or approximately 5 hours after the second dose, and then declined with a half-life of 8.5 hours.
recorded 2026-06-30 · last checked 2026-09-04
Q6
Which running trial of Magnesium Stearate could settle lifespan?
NCT03088852 measures compare mortality, reading out 2026-12.
1 open trial; n 330; "Magnesium Deficiency In Patients Hospitalized in Internal Medicine Wards"
Show the evidence
TrialNCT03088852
"Magnesium Deficiency In Patients Hospitalized in Internal Medicine Wards"; n 330; "compare mortality"; 2026-12
Q7
Which 167 trials of Magnesium Stearate posted no result?
Posted no result
167 of 167 completed trials
Registrations
NCT00004399, NCT00000610, NCT00040235, NCT00004730, NCT00120588 and NCT00325299, and 161 more
Completion dates
oldest 2000-08; newest 2024-06-15
Show the evidence
Trial
NCT00004399
2000-08
NCT00000610
2003-11
NCT00040235
2004-02
NCT00004730
2005-05
NCT00120588
2005-07
NCT00325299
2005-09
14 further recorded trials
NCT00029510
2006-06
NCT00553072
2006-08
NCT00346658
2006-09
NCT00014989
2007-06
NCT01136421
2007-06
NCT00603499
2007-11
NCT00405977
2008-08
NCT00994981
2008-10
NCT00702910
2008-10-04
NCT00704990
2009-12
NCT00933868
2010-07
NCT01032213
2010-10
NCT01205997
2011-01
NCT01332734
2011-01
Q8
At the median, Magnesium Stearate's trials enrolled 74 people — anything larger?
Median enrolment
74
Largest enrolment
87500
Registered trials counted
383
Where it is registeredIdentifiers, relations and other names
ClinicalTrials.gov — US Government work · mixed register set; per-register licences in docs/specs/corpus-20k-sources.md · openFDA / DailyMed — US Government work
✗ required summary fields resolved: 4 required field(s) not terminal: Why people use it, Best-supported result, Biggest unanswered question, Human evidence
✓ public claims reviewed: 0 reviewed claim(s); drafts are never rendered
✓ source coverage passed: 5 source rows
✓ no critical contamination: no quarantine open
✓ canonical metadata passed: slug and display name present
✓ no raw internal fields: enforced by the copy-contract test over the rendered page
This is a record of evidence. It is not medical advice, and it does not say this substance suits you. Nothing here says any substance on RNAWiki is appropriate for a child.