This page shows what was measured, who it was measured in, and what that does not settle.
What Magnesium does in the body
SUPREP Bowel Prep Kit is indicated for cleansing of the colon as a preparation for colonoscopy in adult and pediatric patients 12 years of age and older.
From the FDA-approved label: DIANEAL peritoneal dialysis solutions are a pharmacologically inactive, hypertonic peritoneal dialysis solution containing dextrose, a monosaccharide, as the primary osmotic agent. An osmotic gradient must be created between the peritoneal membrane and the dialysis solution in order for ultrafiltration to occur. The hypertonic concentration of glucose in DIANEAL solutions exert an osmotic pressure across the peritoneal membrane resulting in transcapillary ultrafiltration. Like other peritoneal dialysis solutions, DIANEAL solutions contain electrolytes to facilitate the correction of electrolyte abnormalities.
Why people take it. SUPREP Bowel Prep Kit is indicated for cleansing of the colon as a preparation for colonoscopy in adult and pediatric patients 12 years of age and older.
What happened in people
RNAWiki has not yet published a reviewed conclusion for this use.
§ A fixed RNAWiki sentence
Where this came from
Wording RNAWiki always uses, not a finding about this substance.
No reviewed claim names a result for any goal on this record.
No source is stored against this line.
The limit that matters most
Not recorded.
Where it acts
Not recorded.
Kind of result
No result is published, so no kind of result applies yet
Supervision
Not usually supervised: sold as a supplement or food ingredient where recorded. That is a legal category, not a safety judgement.
What the registries record it as
The substance registry classes this as chemical.
FDA substance registry · I38ZP9992A · read 2026-08-29
The supplement label database classes it as mineral, under the name Calcium.
The use the label states, quoted from it. No plain-language version of this sentence has been written.
The use the label states, quoted from it. It is written for a clinician, not for a reader without medical training.
No statement of the main limit is recorded.
The four opening statements run to 146 words.
Words this page uses
Four words worth knowing first
Chosen from what this page shows, with each one explained before the word it depends on.
Biomarker
A biomarker is a number from a test that stands in for something about health.
A picture of it, and where the picture fails
A biomarker is like a fuel gauge.
Where that stops being true. A gauge is wired to the tank. Many biomarkers are only loosely tied to health.
What people get wrong. A better number is read as a better life. Several medicines improved a number and helped nobody.
A measurable indicator used as a substitute for a clinical outcome of interest.
Placebo
A placebo is a dummy treatment given so the real one can be compared with it.
A picture of it, and where the picture fails
A placebo is like a blank control in an experiment.
Where that stops being true. A blank does nothing. People given a placebo often do get better.
What people get wrong. A placebo effect is read as imaginary. The improvement is measured and real.
An inactive intervention matched in appearance to the test intervention, used to control for non-specific effects.
Comparator
A comparator is whatever the treatment was measured against.
A picture of it, and where the picture fails
It is like the other runner in a race.
Where that stops being true. A race has one winner. A study can show both arms improved.
What people get wrong. Results are read without asking what the other group got. Beating nothing is not beating a treatment.
The control condition against which the experimental intervention is assessed.
What happened in people◇Read from sources, not yet reviewed
What happened in people
Each card is one study: the exact question it asked, who was in it, and whether it showed what it set out to show.
Perinatal mortality
✗ The study did not show it
Who was studied
NCT01994304
How many people
200000
Study design
Not applicable
Compared against
Not recorded for this study
Kind of result
Living longer, or avoiding a major event
What was found
Result not recorded on this page
Repeated elsewhere
Unreplicated
What this does not prove. A study that did not show an effect does not show that no effect exists anywhere.
The limits of this study, and where it came from
Main limit. No limitation is recorded for this study.
How far it carries. This study is recorded from the curated record, not from the registry match.
Form and route. Oral
Interval reported. Not recorded in this summary
Written into the record, not signed off as a reviewed claim.
openFDA NDC Directory · a recorded source, not a stored snapshot
openFDA SPL label · a recorded source, not a stored snapshot
NIH Dietary Supplement Label Database · a recorded source, not a stored snapshot
PubChem PUG-REST · a recorded source, not a stored snapshot
Maternal or Perinatal death or morbidity
✗ The study did not show it
Who was studied
NCT01911494
How many people
87500
Study design
Not applicable
Compared against
Not recorded for this study
Kind of result
Living longer, or avoiding a major event
What was found
Result not recorded on this page
Repeated elsewhere
Unreplicated
What this does not prove. A study that did not show an effect does not show that no effect exists anywhere.
The limits of this study, and where it came from
Main limit. No limitation is recorded for this study.
How far it carries. This study is recorded from the curated record, not from the registry match.
Form and route. Oral
Interval reported. Not recorded in this summary
Written into the record, not signed off as a reviewed claim.
openFDA NDC Directory · a recorded source, not a stored snapshot
openFDA SPL label · a recorded source, not a stored snapshot
NIH Dietary Supplement Label Database · a recorded source, not a stored snapshot
PubChem PUG-REST · a recorded source, not a stored snapshot
A composite of all-cause mortality or major cardiovascular-related hospitalizations
✗ The study did not show it
Who was studied
NCT04079582
How many people
25000
Study design
Not applicable
Compared against
Not recorded for this study
Kind of result
Living longer, or avoiding a major event
What was found
Result not recorded on this page
Repeated elsewhere
Unreplicated
What this does not prove. A study that did not show an effect does not show that no effect exists anywhere.
The limits of this study, and where it came from
Main limit. No limitation is recorded for this study.
How far it carries. This study is recorded from the curated record, not from the registry match.
Form and route. Oral
Interval reported. Not recorded in this summary
Written into the record, not signed off as a reviewed claim.
openFDA NDC Directory · a recorded source, not a stored snapshot
openFDA SPL label · a recorded source, not a stored snapshot
NIH Dietary Supplement Label Database · a recorded source, not a stored snapshot
PubChem PUG-REST · a recorded source, not a stored snapshot
Total Number of Participants Randomized Within Each Appendix
✗ The study did not show it
Who was studied
NCT04885530
How many people
10956
Study design
Phase 3
Compared against
Not recorded for this study
Kind of result
A number that stands in for health
What was found
Result not recorded on this page
Repeated elsewhere
Unreplicated
What this does not prove. A study that did not show an effect does not show that no effect exists anywhere.
The limits of this study, and where it came from
Main limit. No limitation is recorded for this study.
How far it carries. This study is recorded from the curated record, not from the registry match.
Form and route. Oral
Interval reported. Not recorded in this summary
Written into the record, not signed off as a reviewed claim.
openFDA NDC Directory · a recorded source, not a stored snapshot
openFDA SPL label · a recorded source, not a stored snapshot
NIH Dietary Supplement Label Database · a recorded source, not a stored snapshot
PubChem PUG-REST · a recorded source, not a stored snapshot
Occurrence of severe COVID-19 disease among individuals vaccinated with AZD1222,
✗ The study did not show it
Who was studied
NCT05715944
How many people
10888
Study design
Phase 3
Compared against
Not recorded for this study
Kind of result
A number that stands in for health
What was found
Result not recorded on this page
Repeated elsewhere
Unreplicated
What this does not prove. A study that did not show an effect does not show that no effect exists anywhere.
The limits of this study, and where it came from
Main limit. No limitation is recorded for this study.
How far it carries. This study is recorded from the curated record, not from the registry match.
Form and route. Oral
Interval reported. Not recorded in this summary
Written into the record, not signed off as a reviewed claim.
openFDA NDC Directory · a recorded source, not a stored snapshot
openFDA SPL label · a recorded source, not a stored snapshot
NIH Dietary Supplement Label Database · a recorded source, not a stored snapshot
PubChem PUG-REST · a recorded source, not a stored snapshot
Proportion of participants with Major Adverse Kidney Events within 30 days (MAKE30)
✗ The study did not show it
Who was studied
NCT04102371
How many people
9041
Study design
Phase 3
Compared against
Not recorded for this study
Kind of result
A number that stands in for health
What was found
Result not recorded on this page
Repeated elsewhere
Unreplicated
What this does not prove. A study that did not show an effect does not show that no effect exists anywhere.
The limits of this study, and where it came from
Main limit. No limitation is recorded for this study.
How far it carries. This study is recorded from the curated record, not from the registry match.
Form and route. Oral
Interval reported. Not recorded in this summary
Written into the record, not signed off as a reviewed claim.
openFDA NDC Directory · a recorded source, not a stored snapshot
openFDA SPL label · a recorded source, not a stored snapshot
NIH Dietary Supplement Label Database · a recorded source, not a stored snapshot
PubChem PUG-REST · a recorded source, not a stored snapshot
What we know
RNAWiki holds 6 written-up human studies for this substance, each with the question it asked.
How we know it
Each card names the study, the number of people and what the study set out to measure.
What this does not prove
These summaries were written by a person and have not been signed off as reviewed claims.
Why it matters
A study that failed is as informative as one that worked, and both are here.
What we still do not know
No reviewed claim exists, so no exact population, effect size or interval is published yet.
What is missing or unclear◇Read from sources, not yet reviewed
Were people like you studied?
RNAWiki cannot tell whether a study fits you. It can show who was in it, and where the result stops carrying.
Who was studied
People similar to this profile were included.
Temporarily relieves occasional sleeplessness, dry and hard stools, and menstrual cramps. Label footnote: Claims based on traditional homeopathic practice, not accepted medical evidence. Not FDA evaluated. This product is not intended to diagnose, treat, cure, or prevent any disease.
Who is missing from the studies
Which groups were under-represented in the studies has not been recorded for this substance. Pregnancy, breastfeeding, children, older adults, and people with liver or kidney conditions are commonly excluded from trials; nothing here says whether they were.
What the label states about particular groups
On pediatric, the label states: “The safety and effectiveness of SUPREP Bowel Prep Kit in pediatric patients less than 12 years of age have not been established.”
US prescribing information · 50f23abd-6a66-44cb-960e-d43c16a5ae5f · read 2026-08-30
On older people, the label states: “Of the 375 patients who received SUPREP Bowel Prep Kit in clinical trials, 94 (25%) were 65 years of age or older, and 25 (7%) were 75 years of age or older.”
US prescribing information · 50f23abd-6a66-44cb-960e-d43c16a5ae5f · read 2026-08-30
On people who are pregnant, the label states: “Risk Summary There are no available data on SUPREP Bowel Prep Kit use in pregnant women to evaluate for a drug-associated risk of major birth defects, miscarriage, or adverse maternal or fetal outcomes.”
US prescribing information · 50f23abd-6a66-44cb-960e-d43c16a5ae5f · read 2026-08-30
On people who are breastfeeding, the label states: “Risk Summary There are no data available data on the presence of SUPREP Bowel Prep Kit in human or animal milk, the effects on the breastfed child, or the effects on milk production.”
US prescribing information · 50f23abd-6a66-44cb-960e-d43c16a5ae5f · read 2026-08-30
On people with reduced kidney function, the label states: “Use SUPREP Bowel Prep Kit with caution in patients with renal impairment or patients taking concomitant medications that may affect renal function.”
US prescribing information · 50f23abd-6a66-44cb-960e-d43c16a5ae5f · read 2026-08-30
Where the result stopped carrying
This is a scope explorer, not a diagnosis engine.
It shows who was studied so you can see whether people similar to you were included.
RNAWiki cannot tell whether a study fits you. It can show who was in it.
What it would be like to take◇Read from sources, not yet reviewed
Why it might seem to do nothing
A real effect and a noticed effect are different things. These are the recorded reasons the two come apart.
It was studied in different people
The people in the studies were not much like the reader.
On this record: Which groups were under-represented in the studies has not been recorded for this substance. Pregnancy, breastfeeding, children, older adults, and people with liver or kidney conditions are commonly excluded from trials; nothing here says whether they were.
The evidence may simply be wrong
Small early studies often do not hold up.
On this record: RNAWiki has not yet published a reviewed conclusion for this use.
Other reasons RNAWiki checked and found nothing for (11)
It was studied for a different goal
The studies measured something else entirely. Nothing in this record points to this reason.
A different form was studied
The studied form is not the form on the shelf. Nothing in this record points to this reason.
There was nothing to correct
Where a level is already normal, topping it up may change nothing. Nothing in this record points to this reason.
Something else had to happen too
In the studies it was paired with training, a diet or another treatment. Nothing in this record points to this reason.
The change is too small to feel
A real change can still sit below what a person notices. Nothing in this record points to this reason.
Day-to-day swing hides it
Sleep, food, stress and time of day move most numbers more than this would. Nothing in this record points to this reason.
Not enough time yet
The studies ran longer than the person has waited. Nothing in this record points to this reason.
It was not taken as studied
Missed days change the result, and studies count them. Nothing in this record points to this reason.
Something else changed at the same time
Two changes at once cannot be told apart afterwards. Nothing in this record points to this reason.
The product may not be what it says
Contents of a sold product are not always what the label states. Nothing in this record points to this reason.
No recorded reason
RNAWiki has nothing stored that would explain it. Nothing in this record points to this reason.
None of these is a reason to take more. Taking more is not a step this page ever suggests.
What it would be like to take◇Read from sources, not yet reviewed
What taking it involves
The recorded facts about getting hold of it and using it. Nothing here is a suggestion about what you should do.
How it is supplied
Varies by country
❝ Quoted from a source
Where this came from
Copied from a source RNAWiki stored, with the source named.
Read from the recorded approval status.
No source is stored against this line.
Form and route
Oral
✎ Source-linked record
Where this came from
A person wrote this into the record with the study named beside it. No reviewer has signed it off.
The form and route recorded on this substance.
No source is stored against this line.
Who oversees it
Not usually supervised: sold as a supplement or food ingredient where recorded. That is a legal category, not a safety judgement.
❝ Quoted from a source
Where this came from
Copied from a source RNAWiki stored, with the source named.
The identity record classes it as a supplement ingredient; no medicines register records an approval.
No source is stored against this line.
What is in the pack
Sold as liquid, capsule, gelatin coated, pellet, powder, given by the oral, topical, sublingual route.
✎ Source-linked record
Where this came from
A person wrote this into the record with the study named beside it. No reviewer has signed it off.
Recorded notes on how this is sold and what that means for what is in the pack.
No source is stored against this line.
Where it is registered
Regulatory records are listed in the technical disclosure at the foot of this page.
# Counted from records
Where this came from
A count of rows RNAWiki holds. It describes our records, not your body.
Register entries are stored per jurisdiction and shown with their dates.
No source is stored against this line.
Why people stop
Not recorded.
∅ Nothing recorded
Where this came from
RNAWiki holds nothing here and says so rather than guessing.
No record of why people stopped taking it is stored for this substance.
No source is stored against this line.
What it would be like to take∅Nothing found in the sources checked
What can go wrong
Sorted by where each line came from. A regulator's label and a report somebody sent in are not the same kind of fact.
∅Nothing found in the sources checked
No harm is recorded against this substance in the sources RNAWiki checked. Finding nothing is not the same as showing there is nothing.
The sources listed were searched and held nothing. That is not the same as nothing existing.
Over a long time. No completed tested study window is recorded, so long-term effects are not established by the registry record.
Groups the studies covered thinly. Which groups were under-represented in the studies has not been recorded for this substance. Pregnancy, breastfeeding, children, older adults, and people with liver or kidney conditions are commonly excluded from trials; nothing here says whether they were.
What is missing or unclear◇Read from sources, not yet reviewed
Does the exact form matter?
Evidence belongs to the exact thing that was tested. A different salt, a different mixture or a different preparation is a different question.
The form that was studied
Oral
✎ Source-linked record
Where this came from
A person wrote this into the record with the study named beside it. No reviewer has signed it off.
The form used in the studies cited on this page.
No source is stored against this line.
What is sold
Not recorded.
∅ Nothing recorded
Where this came from
RNAWiki holds nothing here and says so rather than guessing.
Nothing further is recorded about which forms are sold.
No source is stored against this line.
What is recorded as being sold
148 products list this as an active ingredient in the United States drug directory. 105 of them contain it and nothing else.
FDA National Drug Code directory · 71399-0053 · read 2026-08-29
They are sold as capsule, gelatin coated, crystal, granule, injection, solution, liquid and pellet, taken intravenous, oral, sublingual and topical.
FDA National Drug Code directory · 71399-0053 · read 2026-08-29
The regulator's established pharmacologic class for it is calculi dissolution agent [epc], increased large intestinal motility [pe] and inhibition large intestine fluid/electrolyte absorption [pe].
FDA National Drug Code directory · 71399-0053 · read 2026-08-29
196 published labels name it as an active ingredient. 153 of them describe this substance alone, which is where its own label text on this page comes from.
US prescribing information · 597caf33-5107-9dec-e063-6294a90a5fcd · read 2026-08-29
Those labels are classed as human otc drug and human prescription drug.
US prescribing information · 597caf33-5107-9dec-e063-6294a90a5fcd · read 2026-08-29
39884 marketed supplement labels list this ingredient, classed as mineral and other combinations.
Those labels carry all other, nutrient and structure/function claims. A claim of that kind is written by the manufacturer and is not assessed by any regulator, so its presence says nothing about whether it is true.
SUPREP Bowel Prep is oral at 3 DOSAGE FORMS AND STRENGTHS SUPREP Bowel Prep Kit (for adults) : Two bottles each containing 6 ounces of an oral solution of 17.5 grams sodium sulfate, 3.13 grams potassium sulfate, and 1.6 grams magnesium sulfate as a…, recorded as fda label in effect 2026-01-31 in the United States.
US prescribing information · 50f23abd-6a66-44cb-960e-d43c16a5ae5f · read 2026-08-30
Recorded price in US: 0.00637 USD per one millilitre, across 5 priced products whose strengths and pack forms differ, as of 2026-08-26, paid by retail pharmacies buying the product, as surveyed by the Centers for Medicare & Medicaid Services. It is not a list price, an insurance price, or what anyone pays at a counter..
Recorded source · 2026-08-26 · read 2026-08-28
Evidence carries across two names for one substance. It does not carry across a salt, a mirror form or a mixture.
What it would be like to take◇Read from sources, not yet reviewed
What you could measure
Watching one thing carefully can tell you whether it moved. It cannot tell you what moved it.
This is sold without a prescription, so a person can sensibly watch one thing and see whether it moves.
Pick one goal. One goal only. Two at once cannot be told apart afterwards.
Pick one thing to watch. No registered study lists a measure RNAWiki could read for this.
Measure before you start. Take the same measurement several times first. One reading is not a starting point.
Know the swing. Write down how much it moves on its own across a normal week.
Change one thing. Change nothing else at the same time, including training and sleep.
Give it the study length. No finished study window is recorded, so no length is suggested here.
Track whether you took it. Missed days are the most common reason a home test shows nothing.
Read the trend. Look at the line across weeks. A single reading tells you almost nothing.
What not to measure
Anything that swings more day to day than the change you are looking for.
A wearable estimate of sleep stages, which is an estimate and not a measurement.
Weight on one morning, which mostly records water.
A feeling you did not write down before starting.
When to stop
Stop if something new and unpleasant starts, and ask a pharmacist or doctor.
Stop if you cannot keep everything else steady, because the result will not mean anything.
Stop at the end of the window you set, and read the trend then.
Tracking can show whether something changed for you. It cannot show what caused it.
RNAWiki does not work out an amount for anyone.
What is missing or unclear◇Read from sources, not yet reviewed
What nobody knows yet
Open questions, each with why it is open and what would close it.
Missing populations
Which groups were under-represented in the studies has not been recorded.
Why it matters. Recorded by the evidence model as a gap on this record.
What would answer it
A study that measures it, and a reviewer to sign it off.
Last checked 2026-09-04. Searched: The sources listed in the receipts at the foot of this page.
Missing long-term data
No completed tested study window is recorded.
Why it matters. Recorded by the evidence model as a gap on this record.
What would answer it
A study that measures it, and a reviewer to sign it off.
Last checked 2026-09-04. Searched: The sources listed in the receipts at the foot of this page.
No reviewed conclusion
RNAWiki has not yet published a reviewed conclusion for this use.
Why it matters. Recorded by the evidence model as a gap on this record.
What would answer it
A study that measures it, and a reviewer to sign it off.
Last checked 2026-09-04. Searched: The sources listed in the receipts at the foot of this page.
Missing interaction studies
No interaction was found in the registers checked. Not finding one is not the same as showing there is none.
Why it matters. Recorded by the evidence model as a gap on this record.
What would answer it
A study that measures it, and a reviewer to sign it off.
Last checked 2026-09-04. Searched: The sources listed in the receipts at the foot of this page.
Formulation uncertainty
Several salts, forms or products of Magnesium are recorded. Results from one form may not transfer to another.
Why it matters. Recorded by the evidence model as a gap on this record.
What would answer it
A study that measures it, and a reviewer to sign it off.
Last checked 2026-09-04. Searched: The sources listed in the receipts at the foot of this page.
Mechanism not reviewed
No reviewed mechanism story exists for this substance.
Why it matters. Recorded by the evidence model as a gap on this record.
What would answer it
A study that measures it, and a reviewer to sign it off.
Last checked 2026-09-04. Searched: The sources listed in the receipts at the foot of this page.
What happened in people◇Read from sources, not yet reviewed
Check any of this yourself
Every line above traced back to the study it came from. This is the technical layer, and the vocabulary changes here.
How many documents were read
125 documents were read for this substance.
RNAWiki source record
6 of them state the same halfLife, and they agree.
RNAWiki source record
6 of them state the same tMax, and they agree.
RNAWiki source record
Where else this substance is registered
FDA substance identifier (UNII)
I38ZP9992A
Checks this page had to pass
✓ Passed
Identity resolved
no open identity hold
✓ Passed
No unresolved merge across substance families
no quarantine open
✓ Passed
Every public sentence names a source
The opening statement carries the origin: Quoted from a stored source.
✗ Not passed
Trial roles classified for highlighted evidence
No registered study is classified as testing this substance.
✓ Passed
No internal keys in reader text
enforced by the copy-contract test over the rendered page
✓ Passed
Safety mode resolved
The identity record classes it as a supplement ingredient; no medicines register records an approval.
✓ Passed
Canonical metadata present
slug and display name present
What is missing or unclear◇Read from sources, not yet reviewed
How this medicine reached us
Kept near the foot of the page. A historical event moves up only when it changes something about this substance today.
What the approval register records
46 approved applications cover products containing this substance. The earliest was NDA016822, approved 19710924 to B BRAUN.
This order is fixed in code and does not count clicks or time on the page.
What is not here
9 questions this page could not answer
These sections were prepared and left out because there was nothing to put in them. They are listed rather than hidden, so the gaps in this record are visible.
What was measured, goal by goal — found nothing in the sources checked.
How close this is to real life — found nothing in the sources checked.
The path through the body — found nothing in the sources checked.
Felt, measured, or meaningful — found nothing in the sources checked.
How long anything takes — found nothing in the sources checked.
What it may clash with — found nothing in the sources checked.
Other ways to the same goal — found nothing in the sources checked.
Claims that go past the evidence — found nothing in the sources checked.
What changed on this page — found nothing in the sources checked.
The record as stored
The full record, for auditing
Everything above is built from what is below. This layer keeps the technical vocabulary, record identifiers and every stored row, so a reader who wants to check the page can.
Recorded evidence blocks (10)
Q1
On the Magnesium label: indicated for what?
"Sodium sulfate, potassium sulfate, and magnesium sulfate oral solution is indicated for cleansing of the colon as a preparation for colonoscopy in adult patients. Pediatric use information is approved for Braintree Laboratories, Inc.'s SUPREP BOWEL PREP KIT (sodium sulfate, potassium sulfate, and magnesium sulfate)…": indications and usage on Magnesium's label. DailyMed label · 31d13799-0931-7735-e063-6294a90a6d02 · 2026-06-30
Q2
378 registered trials of Magnesium — at which phases?
Registered studies posting no result
346 of 378
378 registered studies of Magnesium: 130 na, 85 phase4, 81 phase3, 70 phase2, 28 phase1, 16 na or unstated, 5 early phase1. CLINICALTRIALS_SNAPSHOT · 2026-09-01
3483 with a PubMed record
Show the evidence
na
130
phase4
85
phase3
81
phase2
70
phase1
28
na or unstated
16
10 more recorded rows
early phase1
5
completed
209
unknown
77
not yet recruiting
27
recruiting
26
terminated
19
withdrawn
10
active not recruiting
8
enrolling by invitation
1
suspended
1
recorded 2026-09-01 · last checked 2026-09-04
Q3
26 of Magnesium's trials stopped: safety, futility/efficacy, accrual/recruitment, funding/business, other?
safety (2), futility/efficacy (1), accrual/recruitment (9), funding/business (2) and other (12): Magnesium's stop wording, clustered. CLINICALTRIALS_SNAPSHOT · 2026-09-01
"Funding completed"; 26 of 378 registered studies
Show the evidence
Trial
NCT00116623
terminated; "Funding completed"
NCT00306462
terminated; "No enrollment in past year, lack of interest"
NCT00463736
terminated; "enrollment proceeding too slowly"
NCT00998738
terminated; "lack of accrual"
NCT01074918
withdrawn; "none enrolled per PI"
NCT01261702
terminated; "not include patient anymore"
14 further recorded trials
NCT01333488
terminated; "Low accrual"
NCT01426165
terminated; "Issues with recruitment. PI decided to terminate study"
NCT01502761
terminated; "No safety issues. Low enrollment secondary to negative stroke studies 2013"
NCT01627353
terminated; "Funding withdrawn"
NCT01794247
terminated; "low recruitment rate"
NCT02453373
terminated; "The study has achieved its objectives of showing feasibility, safety, and trend for improved mRS. FDA and LRS agreed that this study should be terminated, and that a new, PIVOTAL trial should be started."
NCT02498496
withdrawn; "financing delays"
NCT02521753
terminated; "It was not possible to continue recruiting due to SARSCov2 pandemia. Results obtained at that time were already published"
NCT02523911
withdrawn; "investigator graduated and is not longer at this institution"
NCT02680626
terminated; "Pfannenstiel hysterectomies are now rarely performed so cannot recruit eligible patients"
NCT03206008
terminated; "hard to get an informed concent because of small number of indiaiton of surgery"
NCT03253224
terminated; "Because the principle investigator will participate a visiting scholar program for one year in other country, this study has been terminated."
NCT03439358
suspended; "Could not recruit patients"
NCT03749590
terminated; "The design of the MagPEP trial is no longer in compliance with the current state of science."
recorded 2026-09-01 · last checked 2026-09-04
Q4
Human studies of Magnesium used Magnesium 400Mg — over how long?
Human studies of Magnesium used "Magnesium 400Mg". ClinicalTrials.gov · 2026-09-01
20 recorded entries; human; infusion; also "Magnesium sulfate 50%", "Composition - Magnesium Lactate 470mg, Pyridoxine HCl 5mg", "50% magnesium sulphate"
Magnesium Sulfate Injection 50% Baxter. Number 5430
NCT03088852
Magnesium Citrate 100 MG
14 more recorded rows
humanNCT03208452
10% magnesium sulfate
humanNCT03344679
Magnesium Sulphate 500 mg
humanNCT03846284
Magnesium sulfate 50mg
humanNCT03846284
Magnesium sulfate 30 mg
humanNCT03879707
Magnesium 500Mg Oral Tablet
humanNCT04249804
Magnesium Sulfate 1000 MG
humanNCT04554862
magnesium 10%
humanNCT05164627
infusion; patients will receive Magnesium infusion (10 mg/kg/hr) from the start of the surgery till the end of it.
humanNCT05904808
Oral Magnesium citrate 600mg
humanNCT06376916
Magnesium Sulfate 2 G
humanNCT06376916
Magnesium Sulfate 2 gram/50ml 0.9% NaCl
humanNCT06376916
Magnesium Sulfate 4 G
humanNCT06376916
Magnesium Sulfate 4g/50ml 0.9% NaCl
humanNCT06516861
Magnesium Sulfate 20 MG/ML
recorded 2026-09-01 · last checked 2026-09-04
Q5
Magnesium's half-life is 17 hours — which schedules were studied?
17 hours, the half-life Magnesium's label states: "Absorption and Elimination After administration of sodium sulfate, potassium sulfate, and magnesium sulfate oral solution in six healthy subjects, the time at which serum sulfate reached its highest point (T max ) was approximately 17 hours after the first dose or approximately 5 hours after the second dose, and then…" DailyMed label · 31d13799-0931-7735-e063-6294a90a6d02 · 2026-06-30
tmax 17 hours.
Show the evidence
half lifepharmacokinetics
17 hours; Absorption and Elimination After administration of sodium sulfate, potassium sulfate, and magnesium sulfate oral solution in six healthy subjects, the time at which serum sulfate reached its highest point (T max ) was approximately 17 hours after the first dose or approximately 5 hours after the second dose, and then declined with a half-life of 8.5 hours.
tmaxpharmacokinetics
17 hours; Absorption and Elimination After administration of sodium sulfate, potassium sulfate, and magnesium sulfate oral solution in six healthy subjects, the time at which serum sulfate reached its highest point (T max ) was approximately 17 hours after the first dose or approximately 5 hours after the second dose, and then declined with a half-life of 8.5 hours.
recorded 2026-06-30 · last checked 2026-09-04
Q6
Which running trial of Magnesium could settle lifespan?
NCT03088852 measures compare mortality, reading out 2026-12.
1 open trial; n 330; "Magnesium Deficiency In Patients Hospitalized in Internal Medicine Wards"
Show the evidence
TrialNCT03088852
"Magnesium Deficiency In Patients Hospitalized in Internal Medicine Wards"; n 330; "compare mortality"; 2026-12
Q7
Which 160 trials of Magnesium posted no result?
Posted no result
160 of 160 completed trials
Registrations
NCT00004399, NCT00000610, NCT00040235, NCT00004730, NCT00120588 and NCT00325299, and 154 more
Completion dates
oldest 2000-08; newest 2024-06-15
Show the evidence
Trial
NCT00004399
2000-08
NCT00000610
2003-11
NCT00040235
2004-02
NCT00004730
2005-05
NCT00120588
2005-07
NCT00325299
2005-09
14 further recorded trials
NCT00029510
2006-06
NCT00553072
2006-08
NCT00346658
2006-09
NCT00014989
2007-06
NCT01136421
2007-06
NCT00405977
2008-08
NCT00994981
2008-10
NCT00704990
2009-12
NCT01032213
2010-10
NCT01205997
2011-01
NCT01332734
2011-01
NCT00994006
2011-03
NCT01153256
2011-03
NCT01360060
2011-03
Q8
At the median, Magnesium's trials enrolled 75 people — anything larger?
Median enrolment
75
Largest enrolment
87500
Registered trials counted
373
Q9
What do 1021 spontaneous reports say about Magnesium — and not say?
These are reports people sent to a regulator. They do not show the medicine caused the reaction. Nobody counted how many people took the medicine and reported nothing. The same event can be reported more than once, and many reports are incomplete. News coverage, lawsuits and new warnings change how often people report. A count is not a rate and not a risk.
Magnesium appears in spontaneous reports to regulators. Across the 10 most-reported reaction terms, 1021 reaction mentions were counted: premature baby 311; premature delivery 161; low birth weight baby 121; hypotension 103. FAERS via Open Targets · CHEMBL1201230 · 2026-06-24
Show the evidence
premature baby
311
premature delivery
161
low birth weight baby
121
hypotension
103
pulmonary oedema
85
macular degeneration
70
4 more recorded rows
hypermagnesaemia
55
hypocalcaemia
46
respiratory failure
36
oxygen saturation decreased
33
recorded 2026-06-24 · last checked 2026-09-04
Q10
Which 10 reactions does Magnesium's label not list?
ClinicalTrials.gov — US Government work · Open Targets 26.06 — CC0 · mixed register set; per-register licences in docs/specs/corpus-20k-sources.md · openFDA / DailyMed — US Government work
✗ required summary fields resolved: 4 required field(s) not terminal: Why people use it, Best-supported result, Biggest unanswered question, Human evidence
✓ public claims reviewed: 0 reviewed claim(s); drafts are never rendered
✓ source coverage passed: 6 source rows
✓ no critical contamination: no quarantine open
✓ canonical metadata passed: slug and display name present
✓ no raw internal fields: enforced by the copy-contract test over the rendered page
This is a record of evidence. It is not medical advice, and it does not say this substance suits you. Nothing here says any substance on RNAWiki is appropriate for a child.