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Fludeoxyglucose F-18

  • Prescription medicine
  • Given by a clinician
  • Identity checked
  • Sources last checked 2026-09-04

This page shows what was measured, who it was measured in, and what that does not settle.

What Fludeoxyglucose F-18 does in the body

Positron emission tomography (PET) imaging in the following settings

From the FDA-approved label: Fludeoxyglucose F 18 is a glucose analog that concentrates in cells that rely upon glucose as an energy source, or in cells whose dependence on glucose increases under pathophysiological conditions. Fludeoxyglucose F 18 is transported through the cell membrane by facilitative glucose transporter proteins and is phosphorylated within the cell to [ 18 F] FDG-6-phosphate by the enzyme hexokinase. Once phosphorylated it cannot exit until it is dephosphorylated by glucose-6-phosphatase.

What happened in people

RNAWiki has not yet published a reviewed conclusion for this use.

A fixed RNAWiki sentence

Where this came from

Wording RNAWiki always uses, not a finding about this substance.

No reviewed claim names a result for any goal on this record.

No source is stored against this line.

The limit that matters most

Not recorded.

Where it acts
Not recorded.
Kind of result
No result is published, so no kind of result applies yet
Supervision
Professional supervision is normally required. A regulator classifies this substance in a way that restricts how it is supplied.

What the registries record it as

  • The substance registry classes this as chemical.

    FDA substance registry · 0Z5B2CJX4D · read 2026-08-29

  • Its recorded molecular formula is C6H11, weighing 181.26.

    US prescribing information · 6b7b71c9-f10c-4ace-8166-ea242d8e628d · read 2026-08-30

Where each sentence above came from

No recorded sentence describes the change this makes in a way that stands on its own. The page opens with what it is taken for instead, and the recorded explanation follows below.

Shown as the opening line on this page.

No statement of the main limit is recorded.

The four opening statements run to 95 words.

Words this page uses

Four words worth knowing first

Chosen from what this page shows, with each one explained before the word it depends on.

Biomarker

A biomarker is a number from a test that stands in for something about health.

A picture of it, and where the picture fails

A biomarker is like a fuel gauge.

Where that stops being true. A gauge is wired to the tank. Many biomarkers are only loosely tied to health.

What people get wrong. A better number is read as a better life. Several medicines improved a number and helped nobody.

A measurable indicator used as a substitute for a clinical outcome of interest.

Placebo

A placebo is a dummy treatment given so the real one can be compared with it.

A picture of it, and where the picture fails

A placebo is like a blank control in an experiment.

Where that stops being true. A blank does nothing. People given a placebo often do get better.

What people get wrong. A placebo effect is read as imaginary. The improvement is measured and real.

An inactive intervention matched in appearance to the test intervention, used to control for non-specific effects.

Comparator

A comparator is whatever the treatment was measured against.

A picture of it, and where the picture fails

It is like the other runner in a race.

Where that stops being true. A race has one winner. A study can show both arms improved.

What people get wrong. Results are read without asking what the other group got. Beating nothing is not beating a treatment.

The control condition against which the experimental intervention is assessed.

What happened in peopleRead from sources, not yet reviewed

What happened in people

Each card is one study: the exact question it asked, who was in it, and whether it showed what it set out to show.

To demonstrate the safety of 18F-FDG synthesized from cyclotron produced radiofluoride in the Coincidence Technologies automated synthesis unit (ASU) in the Edmonton PET Centre facility

The study did not show it

Who was studied
NCT00123760
How many people
10838
Study design
Phase 2/Phase 3
Compared against
Not recorded for this study
Kind of result
A number that stands in for health
What was found
Result not recorded on this page
Repeated elsewhere
Unreplicated

What this does not prove. A study that did not show an effect does not show that no effect exists anywhere.

The limits of this study, and where it came from

Main limit. No limitation is recorded for this study.

How far it carries. This study is recorded from the curated record, not from the registry match.

Form and route. Intravenous

Interval reported. Not recorded in this summary

Written into the record, not signed off as a reviewed claim.

  • openFDA Drugs@FDA · a recorded source, not a stored snapshot
  • openFDA NDC Directory · a recorded source, not a stored snapshot
  • openFDA SPL label · a recorded source, not a stored snapshot
  • PubChem PUG-REST · a recorded source, not a stored snapshot

SUV

The study did not show it

Who was studied
NCT04416165
How many people
3000
Study design
Not applicable
Compared against
Not recorded for this study
Kind of result
A number that stands in for health
What was found
Result not recorded on this page
Repeated elsewhere
Unreplicated

What this does not prove. A study that did not show an effect does not show that no effect exists anywhere.

The limits of this study, and where it came from

Main limit. No limitation is recorded for this study.

How far it carries. This study is recorded from the curated record, not from the registry match.

Form and route. Intravenous

Interval reported. Not recorded in this summary

Written into the record, not signed off as a reviewed claim.

  • openFDA Drugs@FDA · a recorded source, not a stored snapshot
  • openFDA NDC Directory · a recorded source, not a stored snapshot
  • openFDA SPL label · a recorded source, not a stored snapshot
  • PubChem PUG-REST · a recorded source, not a stored snapshot

Change From Baseline on the 13-item Alzheimer's Disease Assessment Scale - Cognitive Subscale (ADAS-Cog13)

The study did not show it

Who was studied
NCT02245737
How many people
2218
Study design
Phase 2/Phase 3
Compared against
Not recorded for this study
Kind of result
A number that stands in for health
What was found
Result not recorded on this page
Repeated elsewhere
Unreplicated

What this does not prove. A study that did not show an effect does not show that no effect exists anywhere.

The limits of this study, and where it came from

Main limit. No limitation is recorded for this study.

How far it carries. This study is recorded from the curated record, not from the registry match.

Form and route. Intravenous

Interval reported. Not recorded in this summary

Written into the record, not signed off as a reviewed claim.

  • openFDA Drugs@FDA · a recorded source, not a stored snapshot
  • openFDA NDC Directory · a recorded source, not a stored snapshot
  • openFDA SPL label · a recorded source, not a stored snapshot
  • PubChem PUG-REST · a recorded source, not a stored snapshot

Event-free survival

The study did not show it

Who was studied
NCT00433459
How many people
2134
Study design
Phase 3
Compared against
Not recorded for this study
Kind of result
Living longer, or avoiding a major event
What was found
Result not recorded on this page
Repeated elsewhere
Unreplicated

What this does not prove. A study that did not show an effect does not show that no effect exists anywhere.

The limits of this study, and where it came from

Main limit. No limitation is recorded for this study.

How far it carries. This study is recorded from the curated record, not from the registry match.

Form and route. Intravenous

Interval reported. Not recorded in this summary

Written into the record, not signed off as a reviewed claim.

  • openFDA Drugs@FDA · a recorded source, not a stored snapshot
  • openFDA NDC Directory · a recorded source, not a stored snapshot
  • openFDA SPL label · a recorded source, not a stored snapshot
  • PubChem PUG-REST · a recorded source, not a stored snapshot

Progression-free survival

The study did not show it

Who was studied
NCT00433433
How many people
1952
Study design
Phase 3
Compared against
Not recorded for this study
Kind of result
Living longer, or avoiding a major event
What was found
Result not recorded on this page
Repeated elsewhere
Unreplicated

What this does not prove. A study that did not show an effect does not show that no effect exists anywhere.

The limits of this study, and where it came from

Main limit. No limitation is recorded for this study.

How far it carries. This study is recorded from the curated record, not from the registry match.

Form and route. Intravenous

Interval reported. Not recorded in this summary

Written into the record, not signed off as a reviewed claim.

  • openFDA Drugs@FDA · a recorded source, not a stored snapshot
  • openFDA NDC Directory · a recorded source, not a stored snapshot
  • openFDA SPL label · a recorded source, not a stored snapshot
  • PubChem PUG-REST · a recorded source, not a stored snapshot

Progression-free survival (PFS) in rapid early responder (RER) patients

The study did not show it

Who was studied
NCT05675410
How many people
1875
Study design
Phase 3
Compared against
Not recorded for this study
Kind of result
Living longer, or avoiding a major event
What was found
Result not recorded on this page
Repeated elsewhere
Unreplicated

What this does not prove. A study that did not show an effect does not show that no effect exists anywhere.

The limits of this study, and where it came from

Main limit. No limitation is recorded for this study.

How far it carries. This study is recorded from the curated record, not from the registry match.

Form and route. Intravenous

Interval reported. Not recorded in this summary

Written into the record, not signed off as a reviewed claim.

  • openFDA Drugs@FDA · a recorded source, not a stored snapshot
  • openFDA NDC Directory · a recorded source, not a stored snapshot
  • openFDA SPL label · a recorded source, not a stored snapshot
  • PubChem PUG-REST · a recorded source, not a stored snapshot
What we know
RNAWiki holds 6 written-up human studies for this substance, each with the question it asked.
How we know it
Each card names the study, the number of people and what the study set out to measure.
What this does not prove
These summaries were written by a person and have not been signed off as reviewed claims.
Why it matters
A study that failed is as informative as one that worked, and both are here.
What we still do not know
No reviewed claim exists, so no exact population, effect size or interval is published yet.

What is missing or unclearRead from sources, not yet reviewed

Were people like you studied?

RNAWiki cannot tell whether a study fits you. It can show who was in it, and where the result stops carrying.

Who was studied

People similar to this profile were included.

  • Fludeoxyglucose F18 Injection is indicated for positron emission tomography (PET) imaging in the following settings: Fludeoxyglucose F18 Injection is indicated for positron emission tomography (PET) imaging in the following settings: Oncology: For assessment of abnormal glucose metabolism to assist in the evaluation of malignancy in patients with known or suspected abnormalities found by other testing modalities, or…

Who is missing from the studies

  • Which groups were under-represented in the studies has not been recorded for this substance. Pregnancy, breastfeeding, children, older adults, and people with liver or kidney conditions are commonly excluded from trials; nothing here says whether they were.

What the label states about particular groups

  • On pediatric, the label states: “In the oncology or cardiology settings, the safety and effectiveness of Fludeoxyglucose F 18 Injection have not been established in pediatric patients.”

    US prescribing information · 6b7b71c9-f10c-4ace-8166-ea242d8e628d · read 2026-08-30

  • On people who are pregnant, the label states: “Risk Summary Data from published case series and case reports describe Fludeoxyglucose F 18 Injection crossing the placenta with uptake by the fetus (see Data).”

    US prescribing information · 6b7b71c9-f10c-4ace-8166-ea242d8e628d · read 2026-08-30

  • On people who are breastfeeding, the label states: “Risk Summary A published case report and case series show the presence of Fludeoxyglucose F 18 Injection in human milk following administration.”

    US prescribing information · 6b7b71c9-f10c-4ace-8166-ea242d8e628d · read 2026-08-30

Where the result stopped carrying

  • This is a scope explorer, not a diagnosis engine.
  • It shows who was studied so you can see whether people similar to you were included.

RNAWiki cannot tell whether a study fits you. It can show who was in it.

What it would be like to takeRead from sources, not yet reviewed

Why it might seem to do nothing

A real effect and a noticed effect are different things. These are the recorded reasons the two come apart.

It was studied in different people

The people in the studies were not much like the reader.

On this record: Which groups were under-represented in the studies has not been recorded for this substance. Pregnancy, breastfeeding, children, older adults, and people with liver or kidney conditions are commonly excluded from trials; nothing here says whether they were.

The evidence may simply be wrong

Small early studies often do not hold up.

On this record: RNAWiki has not yet published a reviewed conclusion for this use.

Other reasons RNAWiki checked and found nothing for (11)
It was studied for a different goal
The studies measured something else entirely. Nothing in this record points to this reason.
A different form was studied
The studied form is not the form on the shelf. Nothing in this record points to this reason.
There was nothing to correct
Where a level is already normal, topping it up may change nothing. Nothing in this record points to this reason.
Something else had to happen too
In the studies it was paired with training, a diet or another treatment. Nothing in this record points to this reason.
The change is too small to feel
A real change can still sit below what a person notices. Nothing in this record points to this reason.
Day-to-day swing hides it
Sleep, food, stress and time of day move most numbers more than this would. Nothing in this record points to this reason.
Not enough time yet
The studies ran longer than the person has waited. Nothing in this record points to this reason.
It was not taken as studied
Missed days change the result, and studies count them. Nothing in this record points to this reason.
Something else changed at the same time
Two changes at once cannot be told apart afterwards. Nothing in this record points to this reason.
The product may not be what it says
Contents of a sold product are not always what the label states. Nothing in this record points to this reason.
No recorded reason
RNAWiki has nothing stored that would explain it. Nothing in this record points to this reason.

None of these is a reason to take more. Taking more is not a step this page ever suggests.

What it would be like to takeRead from sources, not yet reviewed

What taking it involves

The recorded facts about getting hold of it and using it. Nothing here is a suggestion about what you should do.

How it is supplied

Given by a clinician

Quoted from a source

Where this came from

Copied from a source RNAWiki stored, with the source named.

Read from the recorded approval status.

No source is stored against this line.

Form and route

Intravenous

Source-linked record

Where this came from

A person wrote this into the record with the study named beside it. No reviewer has signed it off.

The form and route recorded on this substance.

No source is stored against this line.

Who oversees it

Professional supervision is normally required. A regulator classifies this substance in a way that restricts how it is supplied.

Quoted from a source

Where this came from

Copied from a source RNAWiki stored, with the source named.

Suppression classes recorded: S7.

No source is stored against this line.

What is in the pack

Sold as injectable, injection, injection, solution, given by the intravenous, injection route.

Source-linked record

Where this came from

A person wrote this into the record with the study named beside it. No reviewer has signed it off.

Recorded notes on how this is sold and what that means for what is in the pack.

No source is stored against this line.

Where it is registered

Regulatory records are listed in the technical disclosure at the foot of this page.

Counted from records

Where this came from

A count of rows RNAWiki holds. It describes our records, not your body.

Register entries are stored per jurisdiction and shown with their dates.

No source is stored against this line.

Why people stop

Not recorded.

Nothing recorded

Where this came from

RNAWiki holds nothing here and says so rather than guessing.

No record of why people stopped taking it is stored for this substance.

No source is stored against this line.

What it would be like to takeNothing found in the sources checked

What can go wrong

Sorted by where each line came from. A regulator's label and a report somebody sent in are not the same kind of fact.

Nothing found in the sources checked

No harm is recorded against this substance in the sources RNAWiki checked. Finding nothing is not the same as showing there is nothing.

The sources listed were searched and held nothing. That is not the same as nothing existing.

Over a long time. No completed tested study window is recorded, so long-term effects are not established by the registry record.

Groups the studies covered thinly. Which groups were under-represented in the studies has not been recorded for this substance. Pregnancy, breastfeeding, children, older adults, and people with liver or kidney conditions are commonly excluded from trials; nothing here says whether they were.

What is missing or unclearRead from sources, not yet reviewed

Does the exact form matter?

Evidence belongs to the exact thing that was tested. A different salt, a different mixture or a different preparation is a different question.

The form that was studied

Intravenous

Source-linked record

Where this came from

A person wrote this into the record with the study named beside it. No reviewer has signed it off.

The form used in the studies cited on this page.

No source is stored against this line.

What is sold

Not recorded.

Nothing recorded

Where this came from

RNAWiki holds nothing here and says so rather than guessing.

Nothing further is recorded about which forms are sold.

No source is stored against this line.

What is recorded as being sold

  • 26 products list this as an active ingredient in the United States drug directory. 26 of them contain it and nothing else.

    FDA National Drug Code directory · 24417-001 · read 2026-08-29

  • They are sold as injection and injection, solution, taken intravenous.

    FDA National Drug Code directory · 24417-001 · read 2026-08-29

  • The regulator's established pharmacologic class for it is radioactive diagnostic agent [epc] and radiopharmaceutical activity [moa].

    FDA National Drug Code directory · 24417-001 · read 2026-08-29

  • 26 published labels name it as an active ingredient. 26 of them describe this substance alone, which is where its own label text on this page comes from.

    US prescribing information · 6b7b71c9-f10c-4ace-8166-ea242d8e628d · read 2026-08-29

  • Those labels are classed as human prescription drug.

    US prescribing information · 6b7b71c9-f10c-4ace-8166-ea242d8e628d · read 2026-08-29

  • FLUDEOXYGLUCOSE F-18 is intravenous at 3 DOSAGE FORMS AND STRENGTHS Multiple-dose glass vial containing 0.74 - 11.1GBq (20 - 300 mCi/mL) of Fludeoxyglucose F 18 Injection and 4.5 mg of sodium chloride in Phosphate buffer (25 - 30 mL volume) for intravenous a…, recorded as fda label in effect 2021-11-03 in the United States.

    US prescribing information · 6b7b71c9-f10c-4ace-8166-ea242d8e628d · read 2026-08-30

Evidence carries across two names for one substance. It does not carry across a salt, a mirror form or a mixture.

What it would be like to takeRead from sources, not yet reviewed

What you could measure

This one is decided with a clinician, so this section holds questions to ask rather than a plan to run.

Self-experiment planning is not offered for a prescription or clinician-supervised medicine. The questions below are for a clinician or pharmacist.

Questions worth asking

  • Which of the trials of Fludeoxyglucose F-18 studied people like me?
  • What was measured, and for how long?
  • Was the result a laboratory value or a health outcome?
  • What would we watch for, and when would we stop?

Tracking can show whether something changed for you. It cannot show what caused it.

RNAWiki records evidence. It does not say whether this substance is right for you.

What is missing or unclearRead from sources, not yet reviewed

What nobody knows yet

Open questions, each with why it is open and what would close it.

How much did people take in the studies?

The sources RNAWiki checked hold nothing for this field.

Why it matters. A result belongs to an amount. Without the amount the result floats free.

What would answer it

A stored source that records it, and a reviewer to sign it off.

Last checked 2026-09-04. Searched: The sources listed in the receipts at the foot of this page.

Missing populations

Which groups were under-represented in the studies has not been recorded.

Why it matters. Recorded by the evidence model as a gap on this record.

What would answer it

A study that measures it, and a reviewer to sign it off.

Last checked 2026-09-04. Searched: The sources listed in the receipts at the foot of this page.

Missing long-term data

No completed tested study window is recorded.

Why it matters. Recorded by the evidence model as a gap on this record.

What would answer it

A study that measures it, and a reviewer to sign it off.

Last checked 2026-09-04. Searched: The sources listed in the receipts at the foot of this page.

No reviewed conclusion

RNAWiki has not yet published a reviewed conclusion for this use.

Why it matters. Recorded by the evidence model as a gap on this record.

What would answer it

A study that measures it, and a reviewer to sign it off.

Last checked 2026-09-04. Searched: The sources listed in the receipts at the foot of this page.

Missing interaction studies

No interaction was found in the registers checked. Not finding one is not the same as showing there is none.

Why it matters. Recorded by the evidence model as a gap on this record.

What would answer it

A study that measures it, and a reviewer to sign it off.

Last checked 2026-09-04. Searched: The sources listed in the receipts at the foot of this page.

Formulation uncertainty

Several salts, forms or products of Fludeoxyglucose F-18 are recorded. Results from one form may not transfer to another.

Why it matters. Recorded by the evidence model as a gap on this record.

What would answer it

A study that measures it, and a reviewer to sign it off.

Last checked 2026-09-04. Searched: The sources listed in the receipts at the foot of this page.

Mechanism not reviewed

No reviewed mechanism story exists for this substance.

Why it matters. Recorded by the evidence model as a gap on this record.

What would answer it

A study that measures it, and a reviewer to sign it off.

Last checked 2026-09-04. Searched: The sources listed in the receipts at the foot of this page.

What happened in peopleRead from sources, not yet reviewed

Check any of this yourself

Every line above traced back to the study it came from. This is the technical layer, and the vocabulary changes here.

Where else this substance is registered

FDA substance identifier (UNII)
0Z5B2CJX4D

Checks this page had to pass

  • Passed

    Identity resolved

    no open identity hold

  • Passed

    No unresolved merge across substance families

    no quarantine open

  • Passed

    Every public sentence names a source

    The opening statement carries the origin: Written into the record, not signed off.

  • Not passed

    Trial roles classified for highlighted evidence

    No registered study is classified as testing this substance.

  • Passed

    No internal keys in reader text

    enforced by the copy-contract test over the rendered page

  • Passed

    Safety mode resolved

    Suppression classes recorded: S7.

  • Passed

    Canonical metadata present

    slug and display name present

What is missing or unclearRead from sources, not yet reviewed

How this medicine reached us

Kept near the foot of the page. A historical event moves up only when it changes something about this substance today.

What the approval register records

  • 44 approved applications cover products containing this substance. The earliest was NDA020306, approved 19940819 to DOWNSTATE CLINCL.

    Drugs@FDA application register · NDA020306 · read 2026-08-29

  • Marketing status on the register: discontinued and prescription.

    Drugs@FDA application register · NDA020306 · read 2026-08-29

  • The earliest marketing start date recorded for a listed product is 20050819.

    FDA National Drug Code directory · 24417-001 · read 2026-08-29

What is missing or unclearRead from sources, not yet reviewed

What to learn next

Ordered by what would most change how you read this page, starting with what is easiest to misunderstand.

This order is fixed in code and does not count clicks or time on the page.

What is not here

9 questions this page could not answer

These sections were prepared and left out because there was nothing to put in them. They are listed rather than hidden, so the gaps in this record are visible.

  • What was measured, goal by goal — found nothing in the sources checked.
  • How close this is to real life — found nothing in the sources checked.
  • The path through the body — found nothing in the sources checked.
  • Felt, measured, or meaningful — found nothing in the sources checked.
  • How long anything takes — found nothing in the sources checked.
  • What it may clash with — found nothing in the sources checked.
  • Other ways to the same goal — found nothing in the sources checked.
  • Claims that go past the evidence — found nothing in the sources checked.
  • What changed on this page — found nothing in the sources checked.

The record as stored

The full record, for auditing

Everything above is built from what is below. This layer keeps the technical vocabulary, record identifiers and every stored row, so a reader who wants to check the page can.

Recorded evidence blocks (7)

On the Fludeoxyglucose F-18 label: indicated for what?


"Fludeoxyglucose F 18 Injection USP is indicated for positron emission tomography (PET) imaging in the following settings: Fludeoxyglucose F 18 Injection USP is indicated for positron emission tomography (PET) imaging in the following settings: Oncology: For assessment of abnormal glucose metabolism to assist in the…": indications and usage on Fludeoxyglucose F-18's label. DailyMed label · 09ae2a6d-673a-423a-ba45-3c543061b103 · 2026-07-09

170 registered trials of Fludeoxyglucose F-18 — at which phases?


Registered studies posting no result
120 of 170

170 registered studies of Fludeoxyglucose F-18: 67 phase2, 41 na, 39 phase1, 15 na or unstated, 11 phase3, 9 early phase1, 2 phase4. CLINICALTRIALS_SNAPSHOT · 2026-09-01

13 with a PubMed record

Show the evidence
  • phase2
    67
  • na
    41
  • phase1
    39
  • na or unstated
    15
  • phase3
    11
  • early phase1
    9
9 more recorded rows
  • phase4
    2
  • completed
    78
  • recruiting
    27
  • terminated
    27
  • active not recruiting
    18
  • withdrawn
    8
  • unknown
    7
  • not yet recruiting
    4
  • suspended
    1

recorded 2026-09-01 · last checked 2026-09-04

32 of Fludeoxyglucose F-18's trials stopped: safety, futility/efficacy, accrual/recruitment, funding/business, sponsor decision unspecified, other?


safety (1), futility/efficacy (2), accrual/recruitment (15), funding/business (5), sponsor decision unspecified (2) and other (7): Fludeoxyglucose F-18's stop wording, clustered. CLINICALTRIALS_SNAPSHOT · 2026-09-01

"Principal investigator left the institution."; 32 of 170 registered studies

Show the evidence

Trial

  • NCT00019604
    terminated; "Principal investigator left the institution."
  • NCT00060008
    terminated; "Study was closed early due to poor accrual."
  • NCT00110006
    withdrawn; "No accrual"
  • NCT00253461
    terminated; "Drugs unavailable:unable to make radioactive topotecan"
  • NCT00424138
    terminated; "Recruitment obstacles; data to be combined with other resources for analysis"
  • NCT00794339
    terminated; "transfer of funding"
14 further recorded trials
  • NCT00852644
    terminated; "poor accrual"
  • NCT00953459
    terminated; "poorly recruiting"
  • NCT00958321
    terminated; "Low levels of recruitment"
  • NCT00978874
    terminated; "The PI is no longer with our institution"
  • NCT01169350
    terminated; "funding source ended earlier than anticipated"
  • NCT01283178
    terminated; "The study was terminated. The data analysis was futile with only 3 accruals. PI opted to terminate with IRB and withdraw FDA IND."
  • NCT01314677
    withdrawn; "No subjects have been accrued to this trial. The PI will no longer be at COH and requests a study withdrawal/closure."
  • NCT01494012
    terminated; "low accrual"
  • NCT01789892
    withdrawn; "no patient accrual"
  • NCT01931709
    terminated; "Terminated due to end of funding"
  • NCT02059889
    withdrawn; "slow accrual"
  • NCT02070406
    terminated; "low accrual"
  • NCT02112162
    terminated; "Loss of funding"
  • NCT02149173
    terminated; "Terminated due to low accrual"

recorded 2026-09-01 · last checked 2026-09-04

Fludeoxyglucose F-18's half-life is 0.2 to 0.3 minutes — which schedules were studied?


0.2 to 0.3 minutes, the half-life Fludeoxyglucose F-18's label states: "The effective half-life ranges of the three phases were 0.2 to 0.3 minutes, 10 to 13 minutes with a mean and standard deviation (STD) of 12 ±(1) min, and 80 to 95 minutes with a mean and STD of 88 (±) 4 min." DailyMed label · 09ae2a6d-673a-423a-ba45-3c543061b103 · 2026-07-09

Show the evidence
  • half life pharmacokinetics
    0.2 to 0.3 minutes; The effective half-life ranges of the three phases were 0.2 to 0.3 minutes, 10 to 13 minutes with a mean and standard deviation (STD) of 12 ±(1) min, and 80 to 95 minutes with a mean and STD of 88 (±) 4 min.
  • metabolism pharmacokinetics
    Metabolism : Fludeoxyglucose F 18 is transported into cells and phosphorylated to [F 18]-FDG-6-phosphate at a rate proportional to the rate of glucose utilization within that tissue.

recorded 2026-07-09 · last checked 2026-09-04

Which running trial of Fludeoxyglucose F-18 could settle lifespan?


NCT05886036 measures Progression-free survival (PFS) time, reading out 2026-10-31.

12 open trials; n 70; "Comparing the Effectiveness of the Immunotherapy Agents Rituximab or Mosunetuzumab in Patients With Nodular Lymphocyte-Predominant Hodgkin Lymphoma, NORM Trial"

Show the evidence

Trial

  • NCT05886036
    "Comparing the Effectiveness of the Immunotherapy Agents Rituximab or Mosunetuzumab in Patients With Nodular Lymphocyte-Predominant Hodgkin Lymphoma, NORM Trial"; n 70; "Progression-free survival (PFS) time"; 2026-10-31
  • NCT03952585
    "De-intensified Radiation Therapy With Chemotherapy (Cisplatin) or Immunotherapy (Nivolumab) in Treating Patients With Early-Stage, HPV-Positive, Non-Smoking Associated Oropharyngeal Cancer"; n 384; "Progression-free Survival (PFS) (Phase II) (Percentage of Participants Alive Without Progression)"; 2026-12-11
  • NCT03811015
    "Testing Immunotherapy Versus Observation in Patients With HPV Throat Cancer"; n 636; "Overall survival (OS)"; 2027-01-01
  • NCT04214262
    "Testing the Addition of the Drug Atezolizumab to the Usual Radiation Treatment for Patients With Early Non-small Cell Lung Cancer"; n 415; "Overall survival"; 2027-06-09
  • NCT04665739
    "Testing Lutetium Lu 177 Dotatate in Patients With Somatostatin Receptor Positive Advanced Bronchial Neuroendocrine Tumors"; n 70; "Median progression-free survival (PFS)"; 2027-07-01
  • NCT06820957
    "Testing a New Combination of Anti-cancer Drugs in Patients Newly Diagnosed With Ewing Sarcoma Who Have Cancer That Has Spread to Other Parts of the Body"; n 2; "Time to event-free survival (EFS) post-Consolidation I (C1)"; 2027-08-19
6 further recorded trials
  • NCT04316117
    "Using FDG-PET/CT to Assess Response of Bone-Dominant Metastatic Breast Cancer, FEATURE Study"; n 138; "Performance of fludeoxyglucose F-18 (FDG)-positron emission tomography (PET)/computed tomography (CT) response criteria as a binary predictor of progression-free survival (PFS)"; 2027-08-31
  • NCT04293562
    "A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations"; n 1186; "Event-free survival (EFS)"; 2029-06-30
  • NCT05675410
    "A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab"; n 1875; "Progression-free survival (PFS) in rapid early responder (RER) patients"; 2031-04-28
  • NCT07293247
    "A Study of Targeted Post-Surgery Radiation Therapy for Non-Small Cell Lung Cancer With Remaining Lymph Node Cancer After Treatment"; n 164; "Disease-free survival (DFS)"; 2032-03-01
  • NCT07605416
    "Testing an Experimental Approach to Treat Patients With Plasma Cell Leukemia, The QUANTUM Trial"; n 74; "Overall survival (OS)"; 2032-11-06
  • NCT05976763
    "Testing Continuous Versus Intermittent Treatment With the Study Drug Zanubrutinib for Older Patients With Previously Untreated Mantle Cell Lymphoma"; n 421; "Progression-free survival (PFS) 1 (Arm A)"; 2038-08-31

Which 38 trials of Fludeoxyglucose F-18 posted no result?


Posted no result
38 of 38 completed trials
Registrations
NCT00003429, NCT00004138, NCT00001325, NCT00045045, NCT00238368 and NCT00316901, and 32 more
Completion dates
oldest 2002-10; newest 2024-06-20
Show the evidence

Trial

  • NCT00003429
    2002-10
  • NCT00004138
    2002-12
  • NCT00001325
    2004-06
  • NCT00045045
    2007-07
  • NCT00238368
    2007-09-17
  • NCT00316901
    2007-12
14 further recorded trials
  • NCT00109785
    2008-12
  • NCT00004867
    2009-01
  • NCT00039286
    2009-02
  • NCT00498953
    2009-03
  • NCT01561014
    2009-03
  • NCT00684346
    2010-04
  • NCT00550628
    2011-09
  • NCT00450567
    2012-07
  • NCT01031875
    2012-08
  • NCT01017133
    2012-09
  • NCT00433459
    2013-01
  • NCT01172041
    2013-06
  • NCT01467219
    2014-03
  • NCT00662506
    2014-04

At the median, Fludeoxyglucose F-18's trials enrolled 29 people — anything larger?


Median enrolment
29
Largest enrolment
2134
Registered trials counted
167
Where it is registered
Identifiers, relations and other names

The exact record

ChEMBL id
CHEMBL1808698
PubChem CID
68614
CAS number
63503-12-8
RxCUI
1362737
InChIKey
AOYNUTHNTBLRMT-MXWOLSILSA-N
Also called
CHEMBL1808698, (18F)-FDG, (18F)-FLUORODEOXYGLUCOSE, (18F)FLUORO-2-DEOXYGLUCOSE, 18-F FDG, 18F-FDG, 18F-FLUORODEOXYGLUCOSE, 2-DEOXY-2-(18F)FLUORO-D-GLUCOSE, 2-DEOXY-2-FLUORO-D-GLUCOSE, F-18, FDG F-18
Trade name
Fludeoxyglucose F18
Development code
18-FDG
Sources (4)

Sources

ClinicalTrials.gov — US Government work · mixed register set; per-register licences in docs/specs/corpus-20k-sources.md · openFDA / DailyMed — US Government work

How these records are assembled · Which registers were checked

Index-quality checks
  • identity passed: no open identity hold
  • required summary fields resolved: 4 required field(s) not terminal: Why people use it, Best-supported result, Biggest unanswered question, Human evidence
  • public claims reviewed: 0 reviewed claim(s); drafts are never rendered
  • source coverage passed: 4 source rows
  • no critical contamination: no quarantine open
  • canonical metadata passed: slug and display name present
  • no raw internal fields: enforced by the copy-contract test over the rendered page

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