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Chlorhexidine

  • Prescription medicine
  • Withdrawn
  • Identity checked
  • Sources last checked 2026-09-04

This page shows what was measured, who it was measured in, and what that does not settle.

What Chlorhexidine does in the body

The clinical significance of chlorhexidine gluconate oral rinse's antimicrobial activities is not clear.

From the FDA-approved label: Chlorhexidine gluconate oral rinse provides antimicrobial activity during oral rinsing. Microbiological sampling of plaque has shown a general reduction of counts of certain assayed bacteria, both aerobic and anaerobic, ranging from 54-97% through six months use. Use of chlorhexidine gluconate oral rinse in a six month clinical study did not result in any significant changes in bacterial resistance, overgrowth of potentially opportunistic organisms or other adverse changes in the oral microbial ecosystem.

Why people take it. Gingivitis as characterized by redness and swelling of the gingivae, including gingival bleeding upon probing

What happened in people

RNAWiki has not yet published a reviewed conclusion for this use.

A fixed RNAWiki sentence

Where this came from

Wording RNAWiki always uses, not a finding about this substance.

No reviewed claim names a result for any goal on this record.

No source is stored against this line.

The limit that matters most

Not recorded.

Where it acts
Not recorded.
Kind of result
No result is published, so no kind of result applies yet
Supervision
Professional supervision is normally required. A regulator classifies this substance in a way that restricts how it is supplied.

What the registries record it as

  • The substance registry classes this as chemical.

    FDA substance registry · R4KO0DY52L · read 2026-08-29

  • Its recorded molecular formula is C22H30Cl2N10•2C6H12.

    US prescribing information · 0253513c-148c-4be7-a6d5-5528f40806fa · read 2026-09-12

Where each sentence above came from

A person wrote this explanation into the record, with the studies named in the path below.

The recorded use, written for a reader without medical training. Not signed off.

No statement of the main limit is recorded.

The four opening statements run to 115 words.

Words this page uses

Four words worth knowing first

Chosen from what this page shows, with each one explained before the word it depends on.

Biomarker

A biomarker is a number from a test that stands in for something about health.

A picture of it, and where the picture fails

A biomarker is like a fuel gauge.

Where that stops being true. A gauge is wired to the tank. Many biomarkers are only loosely tied to health.

What people get wrong. A better number is read as a better life. Several medicines improved a number and helped nobody.

A measurable indicator used as a substitute for a clinical outcome of interest.

Placebo

A placebo is a dummy treatment given so the real one can be compared with it.

A picture of it, and where the picture fails

A placebo is like a blank control in an experiment.

Where that stops being true. A blank does nothing. People given a placebo often do get better.

What people get wrong. A placebo effect is read as imaginary. The improvement is measured and real.

An inactive intervention matched in appearance to the test intervention, used to control for non-specific effects.

Comparator

A comparator is whatever the treatment was measured against.

A picture of it, and where the picture fails

It is like the other runner in a race.

Where that stops being true. A race has one winner. A study can show both arms improved.

What people get wrong. Results are read without asking what the other group got. Beating nothing is not beating a treatment.

The control condition against which the experimental intervention is assessed.

What happened in peopleRead from sources, not yet reviewed

What happened in people

Each card is one study: the exact question it asked, who was in it, and whether it showed what it set out to show.

Number of Participants With ICU-attributable Staphylococcus Aureus Clinical Cultures

The study did not show it

Who was studied
NCT03140423
How many people
353323
Study design
Phase 4
Compared against
Not recorded for this study
Kind of result
A number that stands in for health
What was found
Result not recorded on this page
Repeated elsewhere
Unreplicated

What this does not prove. A study that did not show an effect does not show that no effect exists anywhere.

The limits of this study, and where it came from

Main limit. No limitation is recorded for this study.

How far it carries. This study is recorded from the curated record, not from the registry match.

Form and route. Topical

Interval reported. Not recorded in this summary

Written into the record, not signed off as a reviewed claim.

  • openFDA Drugs@FDA · a recorded source, not a stored snapshot
  • openFDA NDC Directory · a recorded source, not a stored snapshot
  • openFDA SPL label · a recorded source, not a stored snapshot
  • PubChem PUG-REST · a recorded source, not a stored snapshot

All-cause Neonatal Mortality

The study did not show it

Who was studied
NCT01241318
How many people
77535
Study design
Phase 2/Phase 3
Compared against
Not recorded for this study
Kind of result
Living longer, or avoiding a major event
What was found
Result not recorded on this page
Repeated elsewhere
Unreplicated

What this does not prove. A study that did not show an effect does not show that no effect exists anywhere.

The limits of this study, and where it came from

Main limit. No limitation is recorded for this study.

How far it carries. This study is recorded from the curated record, not from the registry match.

Form and route. Topical

Interval reported. Not recorded in this summary

Written into the record, not signed off as a reviewed claim.

  • openFDA Drugs@FDA · a recorded source, not a stored snapshot
  • openFDA NDC Directory · a recorded source, not a stored snapshot
  • openFDA SPL label · a recorded source, not a stored snapshot
  • PubChem PUG-REST · a recorded source, not a stored snapshot

Main Outcome: Patients With Nosocomial MRSA Clinical Cultures

The study did not show it

Who was studied
NCT00980980
How many people
74256
Study design
Not applicable
Compared against
Not recorded for this study
Kind of result
A number that stands in for health
What was found
Result not recorded on this page
Repeated elsewhere
Unreplicated

What this does not prove. A study that did not show an effect does not show that no effect exists anywhere.

The limits of this study, and where it came from

Main limit. No limitation is recorded for this study.

How far it carries. This study is recorded from the curated record, not from the registry match.

Form and route. Topical

Interval reported. Not recorded in this summary

Written into the record, not signed off as a reviewed claim.

  • openFDA Drugs@FDA · a recorded source, not a stored snapshot
  • openFDA NDC Directory · a recorded source, not a stored snapshot
  • openFDA SPL label · a recorded source, not a stored snapshot
  • PubChem PUG-REST · a recorded source, not a stored snapshot

Neonatal Mortality

The study did not show it

Who was studied
NCT01528852
How many people
36911
Study design
Phase 3
Compared against
Not recorded for this study
Kind of result
Living longer, or avoiding a major event
What was found
Result not recorded on this page
Repeated elsewhere
Unreplicated

What this does not prove. A study that did not show an effect does not show that no effect exists anywhere.

The limits of this study, and where it came from

Main limit. No limitation is recorded for this study.

How far it carries. This study is recorded from the curated record, not from the registry match.

Form and route. Topical

Interval reported. Not recorded in this summary

Written into the record, not signed off as a reviewed claim.

  • openFDA Drugs@FDA · a recorded source, not a stored snapshot
  • openFDA NDC Directory · a recorded source, not a stored snapshot
  • openFDA SPL label · a recorded source, not a stored snapshot
  • PubChem PUG-REST · a recorded source, not a stored snapshot

Incidence of catheter-related urinary tract infection

The study did not show it

Who was studied
NCT05712434
How many people
30994
Study design
Not applicable
Compared against
Not recorded for this study
Kind of result
A number that stands in for health
What was found
Result not recorded on this page
Repeated elsewhere
Unreplicated

What this does not prove. A study that did not show an effect does not show that no effect exists anywhere.

The limits of this study, and where it came from

Main limit. No limitation is recorded for this study.

How far it carries. This study is recorded from the curated record, not from the registry match.

Form and route. Topical

Interval reported. Not recorded in this summary

Written into the record, not signed off as a reviewed claim.

  • openFDA Drugs@FDA · a recorded source, not a stored snapshot
  • openFDA NDC Directory · a recorded source, not a stored snapshot
  • openFDA SPL label · a recorded source, not a stored snapshot
  • PubChem PUG-REST · a recorded source, not a stored snapshot

Incidence of Skin and Soft Tissue Infection (SSTI)

The study did not show it

Who was studied
NCT01105767
How many people
30209
Study design
Not applicable
Compared against
Not recorded for this study
Kind of result
A number that stands in for health
What was found
Result not recorded on this page
Repeated elsewhere
Unreplicated

What this does not prove. A study that did not show an effect does not show that no effect exists anywhere.

The limits of this study, and where it came from

Main limit. No limitation is recorded for this study.

How far it carries. This study is recorded from the curated record, not from the registry match.

Form and route. Topical

Interval reported. Not recorded in this summary

Written into the record, not signed off as a reviewed claim.

  • openFDA Drugs@FDA · a recorded source, not a stored snapshot
  • openFDA NDC Directory · a recorded source, not a stored snapshot
  • openFDA SPL label · a recorded source, not a stored snapshot
  • PubChem PUG-REST · a recorded source, not a stored snapshot
What we know
RNAWiki holds 6 written-up human studies for this substance, each with the question it asked.
How we know it
Each card names the study, the number of people and what the study set out to measure.
What this does not prove
These summaries were written by a person and have not been signed off as reviewed claims.
Why it matters
A study that failed is as informative as one that worked, and both are here.
What we still do not know
No reviewed claim exists, so no exact population, effect size or interval is published yet.

What is missing or unclearRead from sources, not yet reviewed

Were people like you studied?

RNAWiki cannot tell whether a study fits you. It can show who was in it, and where the result stops carrying.

Who was studied

People similar to this profile were included.

  • Chlorhexidine gluconate oral rinse, 0.12% is indicated for use between dental visits as part of a professional program for the treatment of gingivitis as characterized by redness and swelling of the gingivae, including gingival bleeding upon probing. Chlorhexidine gluconate oral rinse, 0.12% has not been tested among patients with acute necrotizing ulcerative gingivitis (ANUG).

Who is missing from the studies

  • Which groups were under-represented in the studies has not been recorded for this substance. Pregnancy, breastfeeding, children, older adults, and people with liver or kidney conditions are commonly excluded from trials; nothing here says whether they were.

Where the result stopped carrying

  • This is a scope explorer, not a diagnosis engine.
  • It shows who was studied so you can see whether people similar to you were included.

RNAWiki cannot tell whether a study fits you. It can show who was in it.

What it would be like to takeRead from sources, not yet reviewed

Why it might seem to do nothing

A real effect and a noticed effect are different things. These are the recorded reasons the two come apart.

It was studied in different people

The people in the studies were not much like the reader.

On this record: Which groups were under-represented in the studies has not been recorded for this substance. Pregnancy, breastfeeding, children, older adults, and people with liver or kidney conditions are commonly excluded from trials; nothing here says whether they were.

The evidence may simply be wrong

Small early studies often do not hold up.

On this record: RNAWiki has not yet published a reviewed conclusion for this use.

Other reasons RNAWiki checked and found nothing for (11)
It was studied for a different goal
The studies measured something else entirely. Nothing in this record points to this reason.
A different form was studied
The studied form is not the form on the shelf. Nothing in this record points to this reason.
There was nothing to correct
Where a level is already normal, topping it up may change nothing. Nothing in this record points to this reason.
Something else had to happen too
In the studies it was paired with training, a diet or another treatment. Nothing in this record points to this reason.
The change is too small to feel
A real change can still sit below what a person notices. Nothing in this record points to this reason.
Day-to-day swing hides it
Sleep, food, stress and time of day move most numbers more than this would. Nothing in this record points to this reason.
Not enough time yet
The studies ran longer than the person has waited. Nothing in this record points to this reason.
It was not taken as studied
Missed days change the result, and studies count them. Nothing in this record points to this reason.
Something else changed at the same time
Two changes at once cannot be told apart afterwards. Nothing in this record points to this reason.
The product may not be what it says
Contents of a sold product are not always what the label states. Nothing in this record points to this reason.
No recorded reason
RNAWiki has nothing stored that would explain it. Nothing in this record points to this reason.

None of these is a reason to take more. Taking more is not a step this page ever suggests.

What it would be like to takeRead from sources, not yet reviewed

What taking it involves

The recorded facts about getting hold of it and using it. Nothing here is a suggestion about what you should do.

How it is supplied

Withdrawn

Quoted from a source

Where this came from

Copied from a source RNAWiki stored, with the source named.

Read from the recorded approval status.

No source is stored against this line.

Form and route

Topical

Source-linked record

Where this came from

A person wrote this into the record with the study named beside it. No reviewer has signed it off.

The form and route recorded on this substance.

No source is stored against this line.

Who oversees it

Professional supervision is normally required. A regulator classifies this substance in a way that restricts how it is supplied.

Quoted from a source

Where this came from

Copied from a source RNAWiki stored, with the source named.

Suppression classes recorded: S8.

No source is stored against this line.

What is in the pack

Sold as cloth, solution, sponge, swab, given by the topical, dental, buccal route.

Source-linked record

Where this came from

A person wrote this into the record with the study named beside it. No reviewer has signed it off.

Recorded notes on how this is sold and what that means for what is in the pack.

No source is stored against this line.

Where it is registered

Regulatory records are listed in the technical disclosure at the foot of this page.

Counted from records

Where this came from

A count of rows RNAWiki holds. It describes our records, not your body.

Register entries are stored per jurisdiction and shown with their dates.

No source is stored against this line.

Why people stop

Not recorded.

Nothing recorded

Where this came from

RNAWiki holds nothing here and says so rather than guessing.

No record of why people stopped taking it is stored for this substance.

No source is stored against this line.

What it would be like to takeNothing found in the sources checked

What can go wrong

Sorted by where each line came from. A regulator's label and a report somebody sent in are not the same kind of fact.

Nothing found in the sources checked

No harm is recorded against this substance in the sources RNAWiki checked. Finding nothing is not the same as showing there is nothing.

The sources listed were searched and held nothing. That is not the same as nothing existing.

Over a long time. No completed tested study window is recorded, so long-term effects are not established by the registry record.

Groups the studies covered thinly. Which groups were under-represented in the studies has not been recorded for this substance. Pregnancy, breastfeeding, children, older adults, and people with liver or kidney conditions are commonly excluded from trials; nothing here says whether they were.

What is missing or unclearRead from sources, not yet reviewed

Does the exact form matter?

Evidence belongs to the exact thing that was tested. A different salt, a different mixture or a different preparation is a different question.

The form that was studied

Topical

Source-linked record

Where this came from

A person wrote this into the record with the study named beside it. No reviewer has signed it off.

The form used in the studies cited on this page.

No source is stored against this line.

What is sold

Not recorded.

Nothing recorded

Where this came from

RNAWiki holds nothing here and says so rather than guessing.

Nothing further is recorded about which forms are sold.

No source is stored against this line.

What is recorded as being sold

  • 15 products list this as an active ingredient in the United States drug directory. 11 of them contain it and nothing else.

    FDA National Drug Code directory · 84449-004 · read 2026-08-29

  • They are sold as gel, liquid, ointment, patch, powder and solution, taken oral and topical.

    FDA National Drug Code directory · 84449-004 · read 2026-08-29

  • The regulator's established pharmacologic class for it is decreased cell wall integrity [pe].

    FDA National Drug Code directory · 84449-004 · read 2026-08-29

  • 5 published labels name it as an active ingredient. 1 of them describe this substance alone, which is where its own label text on this page comes from.

    US prescribing information · 1eaf21d0-492b-8764-e063-6394a90a6188 · read 2026-08-29

  • Those labels are classed as human otc drug.

    US prescribing information · 1eaf21d0-492b-8764-e063-6394a90a6188 · read 2026-08-29

  • DASH Chlorhexidine Gluconate 0.12% Oral Rinse is oral at Chlorhexidine Gluconate Oral Rinse USP 0.12% is supplied as a blue liquid in the following sizes: Overbagged with 5 x 15 mL amber plastic unit-dose cups in each bag, NDC 55154-1980-5 WARNING: This Unit Dose package is n…, recorded as fda label in effect 2026-04-16 in the United States.

    US prescribing information · 0253513c-148c-4be7-a6d5-5528f40806fa · read 2026-09-12

  • Recorded price in US: 0.00716–0.04109 USD per one millilitre, across 7 priced products whose strengths and pack forms differ, as of 2026-08-26, paid by retail pharmacies buying the product, as surveyed by the Centers for Medicare & Medicaid Services. It is not a list price, an insurance price, or what anyone pays at a counter..

    Recorded source · 2026-08-26 · read 2026-08-28

Evidence carries across two names for one substance. It does not carry across a salt, a mirror form or a mixture.

What it would be like to takeRead from sources, not yet reviewed

What you could measure

This one is decided with a clinician, so this section holds questions to ask rather than a plan to run.

Self-experiment planning is not offered for a prescription or clinician-supervised medicine, withdrawn medicine. The questions below are for a clinician or pharmacist.

Questions worth asking

  • Which of the trials of Chlorhexidine studied people like me?
  • What was measured, and for how long?
  • Was the result a laboratory value or a health outcome?
  • What would we watch for, and when would we stop?

Tracking can show whether something changed for you. It cannot show what caused it.

RNAWiki records evidence. It does not say whether this substance is right for you.

What is missing or unclearRead from sources, not yet reviewed

What nobody knows yet

Open questions, each with why it is open and what would close it.

Missing populations

Which groups were under-represented in the studies has not been recorded.

Why it matters. Recorded by the evidence model as a gap on this record.

What would answer it

A study that measures it, and a reviewer to sign it off.

Last checked 2026-09-04. Searched: The sources listed in the receipts at the foot of this page.

Missing long-term data

No completed tested study window is recorded.

Why it matters. Recorded by the evidence model as a gap on this record.

What would answer it

A study that measures it, and a reviewer to sign it off.

Last checked 2026-09-04. Searched: The sources listed in the receipts at the foot of this page.

No reviewed conclusion

RNAWiki has not yet published a reviewed conclusion for this use.

Why it matters. Recorded by the evidence model as a gap on this record.

What would answer it

A study that measures it, and a reviewer to sign it off.

Last checked 2026-09-04. Searched: The sources listed in the receipts at the foot of this page.

Missing interaction studies

No interaction was found in the registers checked. Not finding one is not the same as showing there is none.

Why it matters. Recorded by the evidence model as a gap on this record.

What would answer it

A study that measures it, and a reviewer to sign it off.

Last checked 2026-09-04. Searched: The sources listed in the receipts at the foot of this page.

Formulation uncertainty

Several salts, forms or products of Chlorhexidine are recorded. Results from one form may not transfer to another.

Why it matters. Recorded by the evidence model as a gap on this record.

What would answer it

A study that measures it, and a reviewer to sign it off.

Last checked 2026-09-04. Searched: The sources listed in the receipts at the foot of this page.

Mechanism not reviewed

No reviewed mechanism story exists for this substance.

Why it matters. Recorded by the evidence model as a gap on this record.

What would answer it

A study that measures it, and a reviewer to sign it off.

Last checked 2026-09-04. Searched: The sources listed in the receipts at the foot of this page.

What happened in peopleRead from sources, not yet reviewed

Check any of this yourself

Every line above traced back to the study it came from. This is the technical layer, and the vocabulary changes here.

Where else this substance is registered

FDA substance identifier (UNII)
R4KO0DY52L
CAS registry number
55-56-1
PubChem compound
2713
ChEMBL
CHEMBL790
ChEBI
3614
WHO international nonproprietary name list entry
500
RxNorm concept
2358
EMA substance identifier
100000081581
European Chemicals Agency number
200-238-7
DrugBank
DB00878

Checks this page had to pass

  • Passed

    Identity resolved

    no open identity hold

  • Passed

    No unresolved merge across substance families

    no quarantine open

  • Passed

    Every public sentence names a source

    The opening statement carries the origin: Written into the record, not signed off.

  • Not passed

    Trial roles classified for highlighted evidence

    No registered study is classified as testing this substance.

  • Passed

    No internal keys in reader text

    enforced by the copy-contract test over the rendered page

  • Passed

    Safety mode resolved

    Suppression classes recorded: S8.

  • Passed

    Canonical metadata present

    slug and display name present

What is missing or unclearRead from sources, not yet reviewed

How this medicine reached us

Kept near the foot of the page. A historical event moves up only when it changes something about this substance today.

  1. Withdrawn; no reason is published (ChEMBL)

What the approval register records

  • The earliest marketing start date recorded for a listed product is 19850101.

    FDA National Drug Code directory · 84449-004 · read 2026-08-29

What is missing or unclearRead from sources, not yet reviewed

What to learn next

Ordered by what would most change how you read this page, starting with what is easiest to misunderstand.

This order is fixed in code and does not count clicks or time on the page.

What is not here

9 questions this page could not answer

These sections were prepared and left out because there was nothing to put in them. They are listed rather than hidden, so the gaps in this record are visible.

  • What was measured, goal by goal — found nothing in the sources checked.
  • How close this is to real life — found nothing in the sources checked.
  • The path through the body — found nothing in the sources checked.
  • Felt, measured, or meaningful — found nothing in the sources checked.
  • How long anything takes — found nothing in the sources checked.
  • What it may clash with — found nothing in the sources checked.
  • Other ways to the same goal — found nothing in the sources checked.
  • Claims that go past the evidence — found nothing in the sources checked.
  • What changed on this page — found nothing in the sources checked.

The record as stored

The full record, for auditing

Everything above is built from what is below. This layer keeps the technical vocabulary, record identifiers and every stored row, so a reader who wants to check the page can.

Recorded evidence blocks (7)

On the Chlorhexidine label: indicated for what?


"Chlorhexidine Gluconate Oral Rinse is indicated for use between dental visits as part of a professional program for the treatment of gingivitis as characterized by redness and swelling of the gingivae, including gingival bleeding upon probing. Chlorhexidine gluconate has not been tested among patients with acute…": indications and usage on Chlorhexidine's label. DailyMed label · acc9ac8e-6f1c-4fcb-880d-dcc03d411ed3 · 2026-07-29

280 registered trials of Chlorhexidine — at which phases?


Registered studies posting no result
209 of 280

280 registered studies of Chlorhexidine: 108 na, 57 phase4, 53 phase3, 47 phase2, 21 phase1, 5 na or unstated, 3 early phase1. CLINICALTRIALS_SNAPSHOT · 2026-09-01

2371 with a PubMed record

Show the evidence
  • na
    108
  • phase4
    57
  • phase3
    53
  • phase2
    47
  • phase1
    21
  • na or unstated
    5
9 more recorded rows
  • early phase1
    3
  • completed
    200
  • unknown
    45
  • terminated
    12
  • recruiting
    11
  • active not recruiting
    5
  • not yet recruiting
    3
  • enrolling by invitation
    2
  • withdrawn
    2

recorded 2026-09-01 · last checked 2026-09-04

14 of Chlorhexidine's trials stopped: safety, futility/efficacy, accrual/recruitment, funding/business, sponsor decision unspecified, other?


safety (1), futility/efficacy (2), accrual/recruitment (3), funding/business (2), sponsor decision unspecified (1) and other (5): Chlorhexidine's stop wording, clustered. CLINICALTRIALS_SNAPSHOT · 2026-09-01

"Study was stopped following interim analysis."; 14 of 280 registered studies

Show the evidence

Trial

  • NCT00528008
    terminated; "Study was stopped following interim analysis."
  • NCT01030666
    terminated; "shelf life of investigational drug ran out before 90 patients could be included"
  • NCT01968356
    terminated; "Study discontinued due to data quality issues."
  • NCT02027324
    withdrawn; "Another study with similar methods was recently published"
  • NCT02221232
    terminated; "To assess product performance (test and reference products), move into further testing."
  • NCT02598778
    terminated; "Study discontinued early due to time constraints and lack of selectivity in agar used in the identification of the target (Streptococcus mutans). Only 12 participants out of a planned 40 were enrolled."
8 further recorded trials
  • NCT03173053
    terminated; "Results interim-analysis"
  • NCT03412734
    terminated; "The institutional review board recommended the study stop enrollment prior to achieving its initial sample size for patient safety."
  • NCT03489512
    withdrawn; "Administrative issues"
  • NCT03854370
    terminated; "COVID impact on recruitment; challenges with enrollment"
  • NCT03859908
    terminated; "Difficulties for recruitment due to COVID-19 pandemia and expiration of the material"
  • NCT04225065
    terminated; "PI does not wish to proceed with study."
  • NCT04748783
    terminated; "Funding withdrawn"
  • NCT06590675
    terminated; "Funding Withdrawn"

recorded 2026-09-01 · last checked 2026-09-04

Human studies of Chlorhexidine used 3.15% chlorhexidine as daily antiseptic on needleless access port — over how long?


studies of Chlorhexidine used the recorded amount. ClinicalTrials.gov · 2026-09-01

20 recorded entries; human; also "3.15% chlorhexidine as daily antiseptic on needleless access port", "Chlorhexidine gluconate 2% w/v and 70% v/v isopropyl alcohol", "4% Chlorhexidine liquid soap"

Show the evidence

human

  • NCT00516360
    3.15% chlorhexidine as daily antiseptic on needleless access port
  • NCT00636480
    Chlorhexidine gluconate 2% w/v and 70% v/v isopropyl alcohol
  • NCT00731783
    4% Chlorhexidine liquid soap
  • NCT00739583
    Chloraprep® (CHG 2% w/v and IPA 70% v/v; Enturia Inc., Leawood, KS, USA)
  • NCT00779246
    Sage 2% Chlorhexidine gluconate cloth
  • NCT01030666
    0.12% chlorhexidine gluconate solution
14 more recorded rows
  • human NCT01030666
    1% chlorhexidine gluconate gel (if necessary)
  • human NCT01036412
    1% Chlorhexidine Gluconate Gel
  • human NCT01079663
    Chlorhexidine 2.5 mg
  • human NCT01115049
    Curasept® ADS 0.20%, Curaden Healthcare
  • human NCT01233050
    2% Chlorhexidine Gluconate/70% Isopropyl Alcohol
  • human NCT01241318
    Chlorhexidine gluconate (4%)
  • human NCT01321125
    2% chlorhexidine gluconate in 70% isopropyl alcohol (ChloraPrep ®, Enturia, Texas, USA )
  • human NCT01495117
    5% CHLORHEXIDINE GLUCONATE SOLUTION (SUNGKWANG PHARM)
  • human NCT01580943
    0,2% CHX non-alcohol base (Corsodyl® Care)
  • human NCT01594827
    4% chlorhexidine gluconate liquid skin cleanser
  • human NCT01844141
    70% alcohol - 0.5% clorhexidine
  • human NCT01857804
    chlorhexidine gluconate 0,2%
  • human NCT01886001
    Chlorhexidine Gluconate 2% w/v;70% Isopropyl Alcohol
  • human NCT01919593
    2% chlorhexidine gluconate in 70% alcohol

recorded 2026-09-01 · last checked 2026-09-04

Which 119 trials of Chlorhexidine posted no result?


Posted no result
119 of 119 completed trials
Registrations
NCT00198679, NCT00066950, NCT00612469, NCT00006075, NCT00610324 and NCT00765167, and 113 more
Completion dates
oldest 2005-03; newest 2024-08-05
Show the evidence

Trial

  • NCT00198679
    2005-03
  • NCT00066950
    2005-08
  • NCT00612469
    2006-10
  • NCT00006075
    2007-08
  • NCT00610324
    2007-12
  • NCT00765167
    2007-12
14 further recorded trials
  • NCT01213550
    2007-12
  • NCT00223002
    2008-01
  • NCT00692484
    2008-02
  • NCT00636480
    2008-03
  • NCT00248300
    2008-08
  • NCT00597688
    2009-04
  • NCT00908817
    2009-05
  • NCT00972803
    2009-05
  • NCT00785200
    2010-02
  • NCT01115049
    2010-03
  • NCT02062047
    2010-04
  • NCT01040286
    2010-06
  • NCT01105195
    2010-11
  • NCT02446158
    2011-05

At the median, Chlorhexidine's trials enrolled 75 people — anything larger?


Median enrolment
75
Largest enrolment
77535
Registered trials counted
277

Where do the label and the trials disagree about Chlorhexidine?


"withdrawn" against "approved": withdrawal status vs register status for Chlorhexidine.

REGISTER_SET, Drugs@FDA; 1 recorded pair

Show the evidence
  • REGISTER_SET CHEMBL790
    withdrawn; 2026-09-04
  • Drugs@FDA NDA019793
    approved; 2026-08-28
Where it is registered

Where it’s registered

Withdrawn; no reason is published (ChEMBL)

Identifiers, relations and other names

The exact record

ChEMBL id
CHEMBL2106050
PubChem CID
9919060
CAS number
77146-42-0
RxCUI
20791
InChIKey
GHXZTYHSJHQHIJ-UHFFFAOYSA-N
Trade name
Gppe wsh, Acriflex, Aerocide 1, Bacticlens, Bioscrub, Brian care, Cepton, Cetriclens, Cetriclens fte, Chg scrub, Chloraprep, Chlorhex glucon
Also called
CHLORHEXIDINE PHOSPHANILATE, CHLORHEXIDINE GLUCONATE, Chlohexidine gluconate, Chlorhexidine d-digluconate, Chlorhexidine digluconate
Development code
BMY-30120, CHP, WP-973, NSC-753971
Sources (6)

Sources

ClinicalTrials.gov — US Government work · mixed register set; per-register licences in docs/specs/corpus-20k-sources.md · openFDA / DailyMed — US Government work

How these records are assembled · Which registers were checked

Index-quality checks
  • identity passed: no open identity hold
  • required summary fields resolved: 4 required field(s) not terminal: Why people use it, Best-supported result, Biggest unanswered question, Human evidence
  • public claims reviewed: 0 reviewed claim(s); drafts are never rendered
  • source coverage passed: 6 source rows
  • no critical contamination: no quarantine open
  • canonical metadata passed: slug and display name present
  • no raw internal fields: enforced by the copy-contract test over the rendered page

This is a record of evidence. It is not medical advice, and it does not say this substance suits you. Nothing here says any substance on RNAWiki is appropriate for a child.