This page shows what was measured, who it was measured in, and what that does not settle.
What Camphor Oil does in the body
Sore muscles and joints associated with strains and sprains backaches lumbago pain of tendons and/or ligaments arthritic or rheumatic pain
What happened in people
RNAWiki has not yet published a reviewed conclusion for this use.
§ A fixed RNAWiki sentence
Where this came from
Wording RNAWiki always uses, not a finding about this substance.
No reviewed claim names a result for any goal on this record.
No source is stored against this line.
The limit that matters most
Not recorded.
Where it acts
Not recorded.
Kind of result
No result is published, so no kind of result applies yet
Supervision
RNAWiki has not recorded a supervision or regulatory status for this substance.
What the registries record it as
The substance registry classes this as structurallydiverse.
FDA substance registry · 75IZZ8Y727 · read 2026-08-29
It is recorded as coming from CINNAMOMUM CAMPHORA WHOLE. The part recorded is bark.
FDA substance registry · 75IZZ8Y727 · read 2026-08-29
Where each sentence above came from
No plain explanation of what this changes is stored. The page opens with what it is taken for instead, and the recorded explanation follows below.
Shown as the opening line on this page.
No statement of the main limit is recorded.
The four opening statements run to 36 words.
Words this page uses
Four words worth knowing first
Chosen from what this page shows, with each one explained before the word it depends on.
Protein
A protein is a folded chain your body builds to do a specific job.
A picture of it, and where the picture fails
A protein is like a tool bent into one shape for one task.
Where that stops being true. A tool keeps its shape. A protein can change shape and stop working.
What people get wrong. Protein in food and a protein in the body are related but not the same thing.
A polymer of amino acids folded into a defined structure that determines its function.
Enzyme
An enzyme is a protein that speeds up one chemical change.
A picture of it, and where the picture fails
An enzyme is like a machine on a production line doing one cut.
Where that stops being true. A machine is switched on and off by a person. Enzymes are controlled by the cell.
What people get wrong. Enzymes are thought to be used up. They are not; they work again and again.
A catalytic protein that lowers the activation energy of a specific reaction.
Receptor
A receptor is a part of a cell that a signal fits into.
A picture of it, and where the picture fails
A receptor is like a lock waiting for one key.
Where that stops being true. A lock either opens or does not. A receptor can be half-triggered, or worn out.
What people get wrong. Fitting a receptor is read as causing a benefit. It causes a step, and nothing more.
A protein that binds a specific ligand and converts that binding into a cellular response.
Pathway
A pathway is a chain of steps inside a cell, each one setting off the next.
A picture of it, and where the picture fails
A pathway is like a row of dominoes.
Where that stops being true. Dominoes fall one way. Pathways loop back and can switch themselves off.
What people get wrong. Changing one step is read as changing the outcome. Other steps often absorb it.
An ordered series of molecular interactions producing a defined cellular change.
What happened in people◇Read from sources, not yet reviewed
What happened in people
Each card is one study: the exact question it asked, who was in it, and whether it showed what it set out to show.
Subjective assessment of cough and congestion symptoms
✗ The study did not show it
Who was studied
NCT00743990
How many people
143
Study design
Not applicable
Compared against
Not recorded for this study
Kind of result
A number that stands in for health
What was found
Result not recorded on this page
Repeated elsewhere
Unreplicated
What this does not prove. A study that did not show an effect does not show that no effect exists anywhere.
The limits of this study, and where it came from
Main limit. No limitation is recorded for this study.
How far it carries. This study is recorded from the curated record, not from the registry match.
Form and route. Topical
Interval reported. Not recorded in this summary
Written into the record, not signed off as a reviewed claim.
openFDA NDC Directory · a recorded source, not a stored snapshot
openFDA SPL label · a recorded source, not a stored snapshot
FDA label (openFDA SPL) · a recorded source, not a stored snapshot
Visual Analog Scale (VAS) for Evaluating Thirst Level
✗ The study did not show it
Who was studied
NCT04994262
How many people
118
Study design
Not applicable
Compared against
Not recorded for this study
Kind of result
A number that stands in for health
What was found
Result not recorded on this page
Repeated elsewhere
Unreplicated
What this does not prove. A study that did not show an effect does not show that no effect exists anywhere.
The limits of this study, and where it came from
Main limit. No limitation is recorded for this study.
How far it carries. This study is recorded from the curated record, not from the registry match.
Form and route. Topical
Interval reported. Not recorded in this summary
Written into the record, not signed off as a reviewed claim.
openFDA NDC Directory · a recorded source, not a stored snapshot
openFDA SPL label · a recorded source, not a stored snapshot
FDA label (openFDA SPL) · a recorded source, not a stored snapshot
The primary study endpoint was the benefits of Essential Oil in reducing symptoms (cough, sputum, fatigue).
✗ The study did not show it
Who was studied
NCT07518394
How many people
105
Study design
Phase 4
Compared against
Not recorded for this study
Kind of result
A number that stands in for health
What was found
Result not recorded on this page
Repeated elsewhere
Unreplicated
What this does not prove. A study that did not show an effect does not show that no effect exists anywhere.
The limits of this study, and where it came from
Main limit. No limitation is recorded for this study.
How far it carries. This study is recorded from the curated record, not from the registry match.
Form and route. Topical
Interval reported. Not recorded in this summary
Written into the record, not signed off as a reviewed claim.
openFDA NDC Directory · a recorded source, not a stored snapshot
openFDA SPL label · a recorded source, not a stored snapshot
FDA label (openFDA SPL) · a recorded source, not a stored snapshot
STROOP TEST
✗ The study did not show it
Who was studied
NCT07563114
How many people
63
Study design
Not applicable
Compared against
Not recorded for this study
Kind of result
A number that stands in for health
What was found
Result not recorded on this page
Repeated elsewhere
Unreplicated
What this does not prove. A study that did not show an effect does not show that no effect exists anywhere.
The limits of this study, and where it came from
Main limit. No limitation is recorded for this study.
How far it carries. This study is recorded from the curated record, not from the registry match.
Form and route. Topical
Interval reported. Not recorded in this summary
Written into the record, not signed off as a reviewed claim.
openFDA NDC Directory · a recorded source, not a stored snapshot
openFDA SPL label · a recorded source, not a stored snapshot
FDA label (openFDA SPL) · a recorded source, not a stored snapshot
Local Skin Perfusion
✗ The study did not show it
Who was studied
NCT03016221
How many people
21
Study design
Not applicable
Compared against
Not recorded for this study
Kind of result
A number that stands in for health
What was found
Result not recorded on this page
Repeated elsewhere
Unreplicated
What this does not prove. A study that did not show an effect does not show that no effect exists anywhere.
The limits of this study, and where it came from
Main limit. No limitation is recorded for this study.
How far it carries. This study is recorded from the curated record, not from the registry match.
Form and route. Topical
Interval reported. Not recorded in this summary
Written into the record, not signed off as a reviewed claim.
openFDA NDC Directory · a recorded source, not a stored snapshot
openFDA SPL label · a recorded source, not a stored snapshot
FDA label (openFDA SPL) · a recorded source, not a stored snapshot
Epigenetic factors influencing muscle metabolism
✗ The study did not show it
Who was studied
NCT04241497
How many people
10
Study design
Not applicable
Compared against
Not recorded for this study
Kind of result
A number that stands in for health
What was found
Result not recorded on this page
Repeated elsewhere
Unreplicated
What this does not prove. A study that did not show an effect does not show that no effect exists anywhere.
The limits of this study, and where it came from
Main limit. No limitation is recorded for this study.
How far it carries. This study is recorded from the curated record, not from the registry match.
Form and route. Topical
Interval reported. Not recorded in this summary
Written into the record, not signed off as a reviewed claim.
openFDA NDC Directory · a recorded source, not a stored snapshot
openFDA SPL label · a recorded source, not a stored snapshot
FDA label (openFDA SPL) · a recorded source, not a stored snapshot
What we know
RNAWiki holds 6 written-up human studies for this substance, each with the question it asked.
How we know it
Each card names the study, the number of people and what the study set out to measure.
What this does not prove
These summaries were written by a person and have not been signed off as reviewed claims.
Why it matters
A study that failed is as informative as one that worked, and both are here.
What we still do not know
No reviewed claim exists, so no exact population, effect size or interval is published yet.
What happened in people◇Read from sources, not yet reviewed
How close this is to real life
The top step is something a person would feel or care about. The bottom is a guess from software. Filled steps are where evidence exists for this substance.
□Living longer, or avoiding a major eventNo evidence recorded. Death, a heart attack, a stroke, a hospital stay.No registered study measures this.
□What a body can do day to dayNo evidence recorded. Walking, dressing, breathing, recovering.No registered study measures this.
□Measured performanceNo evidence recorded. How much was lifted, how far was run, how fast.No registered study measures this.
□Symptoms and quality of lifeNo evidence recorded. Pain, tiredness, mood, sleep, as the person rated it.No registered study measures this.
□A number that stands in for healthNo evidence recorded. Cholesterol, blood sugar, bone density. A stand-in, not the thing itself.No registered study measures this.
■A step measured inside a personEvidence recorded. Something measured in human tissue or human cells.A human record sits on the stored organism ladder.
■AnimalsEvidence recorded. Mice, rats, dogs. Useful for ideas, not proof about people.Stored records in C. elegans (roundworm), Mouse, Dog, Non-human primate. A result in animals says what to test next. It does not say what happens in people.
■Cells in a dishEvidence recorded. Cells or chemistry on a bench, far from a whole body.Stored mechanism abstracts describe steps measured in cells or tissue.
□A guess from softwareNo evidence recorded. Nobody measured it. RNAWiki never publishes one as a finding.RNAWiki stores no prediction for this record. Software can suggest a link. RNAWiki does not publish one as a finding.
Higher on these steps means closer to something a person would feel. It does not mean better done.
What is missing or unclear◇Read from sources, not yet reviewed
Were people like you studied?
RNAWiki cannot tell whether a study fits you. It can show who was in it, and where the result stops carrying.
Who was studied
People similar to this profile were included.
For the temporary relief of sore muscles and joints associated with strains and sprains backaches lumbago pain of tendons and/or ligaments arthritic or rheumatic pain
Who is missing from the studies
Which groups were under-represented in the studies has not been recorded for this substance. Pregnancy, breastfeeding, children, older adults, and people with liver or kidney conditions are commonly excluded from trials; nothing here says whether they were.
Where the result stopped carrying
This is a scope explorer, not a diagnosis engine.
It shows who was studied so you can see whether people similar to you were included.
RNAWiki cannot tell whether a study fits you. It can show who was in it.
What it would be like to take◇Read from sources, not yet reviewed
Why it might seem to do nothing
A real effect and a noticed effect are different things. These are the recorded reasons the two come apart.
It was studied for a different goal
The studies measured something else entirely.
On this record: Some registered studies measured things that match no goal on this page.
It was studied in different people
The people in the studies were not much like the reader.
On this record: Which groups were under-represented in the studies has not been recorded for this substance. Pregnancy, breastfeeding, children, older adults, and people with liver or kidney conditions are commonly excluded from trials; nothing here says whether they were.
The evidence may simply be wrong
Small early studies often do not hold up.
On this record: RNAWiki has not yet published a reviewed conclusion for this use.
Other reasons RNAWiki checked and found nothing for (10)
A different form was studied
The studied form is not the form on the shelf. Nothing in this record points to this reason.
There was nothing to correct
Where a level is already normal, topping it up may change nothing. Nothing in this record points to this reason.
Something else had to happen too
In the studies it was paired with training, a diet or another treatment. Nothing in this record points to this reason.
The change is too small to feel
A real change can still sit below what a person notices. Nothing in this record points to this reason.
Day-to-day swing hides it
Sleep, food, stress and time of day move most numbers more than this would. Nothing in this record points to this reason.
Not enough time yet
The studies ran longer than the person has waited. Nothing in this record points to this reason.
It was not taken as studied
Missed days change the result, and studies count them. Nothing in this record points to this reason.
Something else changed at the same time
Two changes at once cannot be told apart afterwards. Nothing in this record points to this reason.
The product may not be what it says
Contents of a sold product are not always what the label states. Nothing in this record points to this reason.
No recorded reason
RNAWiki has nothing stored that would explain it. Nothing in this record points to this reason.
None of these is a reason to take more. Taking more is not a step this page ever suggests.
What it would be like to take◇Read from sources, not yet reviewed
What taking it involves
The recorded facts about getting hold of it and using it. Nothing here is a suggestion about what you should do.
How it is supplied
Prescription only
❝ Quoted from a source
Where this came from
Copied from a source RNAWiki stored, with the source named.
Read from the recorded approval status.
No source is stored against this line.
Form and route
Topical
✎ Source-linked record
Where this came from
A person wrote this into the record with the study named beside it. No reviewer has signed it off.
The form and route recorded on this substance.
No source is stored against this line.
Who oversees it
RNAWiki has not recorded a supervision or regulatory status for this substance.
❝ Quoted from a source
Where this came from
Copied from a source RNAWiki stored, with the source named.
No register row and no identity class settled the question.
No source is stored against this line.
What is in the pack
Sold as cream, solution, gel, liquid, given by the topical route.
✎ Source-linked record
Where this came from
A person wrote this into the record with the study named beside it. No reviewer has signed it off.
Recorded notes on how this is sold and what that means for what is in the pack.
No source is stored against this line.
Where it is registered
Regulatory records are listed in the technical disclosure at the foot of this page.
# Counted from records
Where this came from
A count of rows RNAWiki holds. It describes our records, not your body.
Register entries are stored per jurisdiction and shown with their dates.
No source is stored against this line.
Why people stop
Not recorded.
∅ Nothing recorded
Where this came from
RNAWiki holds nothing here and says so rather than guessing.
No record of why people stopped taking it is stored for this substance.
No source is stored against this line.
What it would be like to take∅Nothing found in the sources checked
What can go wrong
Sorted by where each line came from. A regulator's label and a report somebody sent in are not the same kind of fact.
∅Nothing found in the sources checked
No harm is recorded against this substance in the sources RNAWiki checked. Finding nothing is not the same as showing there is nothing.
The sources listed were searched and held nothing. That is not the same as nothing existing.
Over a long time. No completed tested study window is recorded, so long-term effects are not established by the registry record.
Groups the studies covered thinly. Which groups were under-represented in the studies has not been recorded for this substance. Pregnancy, breastfeeding, children, older adults, and people with liver or kidney conditions are commonly excluded from trials; nothing here says whether they were.
What is missing or unclear◇Read from sources, not yet reviewed
Does the exact form matter?
Evidence belongs to the exact thing that was tested. A different salt, a different mixture or a different preparation is a different question.
The form that was studied
Topical
✎ Source-linked record
Where this came from
A person wrote this into the record with the study named beside it. No reviewer has signed it off.
The form used in the studies cited on this page.
No source is stored against this line.
What is sold
Not recorded.
∅ Nothing recorded
Where this came from
RNAWiki holds nothing here and says so rather than guessing.
Nothing further is recorded about which forms are sold.
No source is stored against this line.
What is recorded as being sold
7 products list this as an active ingredient in the United States drug directory. None of them contains it on its own, so nothing on this page can separate it from what it is combined with.
FDA National Drug Code directory · 72793-200 · read 2026-08-29
They are sold as cream, gel, liquid, oil and solution, taken topical.
FDA National Drug Code directory · 72793-200 · read 2026-08-29
7 published labels name it as an active ingredient. None of them describes this substance alone, so no label text on this page can be attributed to it rather than to a combination.
US prescribing information · 12652c98-e2a8-21fc-e063-6394a90a94cb · read 2026-08-29
Those labels are classed as human otc drug.
US prescribing information · 12652c98-e2a8-21fc-e063-6394a90a94cb · read 2026-08-29
8958 marketed supplement labels list this ingredient, classed as botanical, fat/fatty acid and other combinations.
Those labels carry all other, nutrient and structure/function claims. A claim of that kind is written by the manufacturer and is not assessed by any regulator, so its presence says nothing about whether it is true.
This order is fixed in code and does not count clicks or time on the page.
What is not here
8 questions this page could not answer
These sections were prepared and left out because there was nothing to put in them. They are listed rather than hidden, so the gaps in this record are visible.
What was measured, goal by goal — found nothing in the sources checked.
The path through the body — found nothing in the sources checked.
Felt, measured, or meaningful — found nothing in the sources checked.
How long anything takes — found nothing in the sources checked.
What it may clash with — found nothing in the sources checked.
Other ways to the same goal — found nothing in the sources checked.
Claims that go past the evidence — found nothing in the sources checked.
What changed on this page — found nothing in the sources checked.
The record as stored
The full record, for auditing
Everything above is built from what is below. This layer keeps the technical vocabulary, record identifiers and every stored row, so a reader who wants to check the page can.
Recorded evidence blocks (11)
Q1
What did Camphor Oil's largest trial (180 people) and its longest (5.9 years) measure?
180 people in Camphor Oil's largest registered study, 5.9 years in its longest registered window, measuring Occurrence of Adverse Events. ClinicalTrials.gov · 2026-09-01
6 na, 2 na or unstated, 1 early phase1; NCT02148731; 2015-12. Last human test completed 2022, NCT06400134.
Interpretation These counts include studies where Camphor Oil was a comparison treatment, a background treatment or an exposure in an observational study, and the longest window may be a planned end date. Trial roles have not yet been classified for this record.
Show the evidence
na
6
na or unstated
2
early phase1
1
Last recorded human testNCT06400134
2022-09-30
recorded 2026-09-01 · last checked 2026-09-04
Q2
From C. elegans to human: where has Camphor Oil shown lifespan?
"The study was terminated after the enrollment of 19 participants due to difficulties in recruitment (an enrollment of 25 participants was originally planned). No safety concerns were raised and no adverse events occurred."; 1 of 9 registered studies
Show the evidence
TrialNCT06173063
terminated; "The study was terminated after the enrollment of 19 participants due to difficulties in recruitment (an enrollment of 25 participants was originally planned). No safety concerns were raised and no adverse events occurred."
recorded 2026-09-01 · last checked 2026-09-04
Q4
Did Camphor Oil move GrimAge, and by how much?
GrimAge: "Data from 6 336 participants from the Irish Longitudinal Study on Ageing (TILDA), the Health and Retirement Study of the United States (HRS) and the Northern Ireland Cohort for the Longitudinal Study of Ageing (NICOLA) are used to investigate the association of accelerated epigenetic age based on 3 clocks (PhenoAge,…" Europe PMC · epigenetic clock search · 2026-02-25
6 recorded sentences; 2025, 2022, 2026; biomarker
Show the evidence
GrimAgePMID 40091605
2025; "Data from 6 336 participants from the Irish Longitudinal Study on Ageing (TILDA), the Health and Retirement Study of the United States (HRS) and the Northern Ireland Cohort for the Longitudinal Study of Ageing (NICOLA) are used to investigate the association of accelerated epigenetic age based on 3 clocks (PhenoAge, GrimAge, and DunedinPACE) with 4 health outcomes (mobility, grip strength,…"
HorvathPMID 36566336
2022; "Diagonal reference modelling and ordinary least square regression techniques were applied to explore social mobility and four measures of age acceleration (first-generation: 'Horvath', 'Hannum' and second-generation: 'Phenoage', DunedinPoAm) in n = 3140 participants of the UK Household Longitudinal Study."
HannumPMID 36566336
2022; "Social mobility was associated with AA measured with Hannum only such that compared to no mobility, upward mobility was associated with greater age independently of origin and destination SEP."
PhenoAge
PMID 36566336
2022; "Compared to continuously advantaged groups, downward mobility was associated with positive Phenoage (1.06y [- 0.03, 2.14]) and DunedinPoAm assessed AA (0.96y [0.24, 1.68])."
PMID 36566336
2022; "For these two measures, upward mobility was associated with negative AA (Phenoage, - 0.65y [- 1.30, - 0.002]; DunedinPoAm, - 0.96y [- 1.47, - 0.46]) compared to continually disadvantaged groups."
epigenetic agePMID 41898792
2026; "This review synthesizes current integrative approaches combining genomic analyses, stable isotope investigations, epigenetic age estimation, proteomic sex determination, and complementary histological techniques to infer sex, ancestry, kinship, age, diet, mobility, and geographic origin."
recorded 2026-02-25 · last checked 2026-09-04
Q5
More Camphor Oil was worse in human: at what point?
U-shaped in human: "Therefore, we devised a fusion surgery and spondylolysis repair combination using a U-shaped rod that preserved L5-S mobility and L4-5 stability." Europe PMC · dose-response search · 2026-08-10
5 recorded sentences naming Camphor Oil; U-shaped, dose-response
Show the evidence
U-shaped
PMID 41971906
"Therefore, we devised a fusion surgery and spondylolysis repair combination using a U-shaped rod that preserved L5-S mobility and L4-5 stability."
"The results show that: (1) traditional masonry follows a characteristic pattern in which large stones form the primary structure while smaller stones provide infill and geometric adjustment; (2) wall irregularity exhibits a pronounced U-shaped distribution along the gradient from mountain resource zones to the historical center, with relatively regular masonry at both ends and a fragmented…"
dose-response
PMID 42580253
"To examine the non-linear dose-response effects of different exercise modalities on handgrip strength and functional mobility in middle-aged and older adults with sarcopenia, and whether modality-dose combinations produce outcome-specific functional responses."
PMID 42580253
"Bayesian model-based network meta-analysis was performed in R to model non-linear dose-response relationships for handgrip strength and functional mobility and compare modality-specific effects across dose ranges."
PMID 42315599
"This study utilizes Bayesian network dose-response meta-analysis (MBNMA) to assess the effects of total exercise dose on balance, stability, motor skills, functional mobility, and coordination in children and adolescents with Down syndrome."
recorded 2026-08-10 · last checked 2026-09-04
Q6
Could one person measure Camphor Oil's effect on occurrence of adverse events?
Occurrence of adverse events: measured in Camphor Oil's trials.
Interpretation occurrence of adverse events is the recorded endpoint.
Show the evidence
biomarkers
occurrence of adverse events; 2026-09-01
loneliness; 2026-09-01
human trials at or under30
2
Not recorded for this substance
a recorded half-life
smallest human trial
15; NCT04851730; NA; the smallest recorded human enrolment at or below 30; the registry states no direction of its result; UNKNOWN
Q7
Which of Camphor Oil's 2 ongoing trials reports first?
Timing of exercises; Upper limb function test; latest 2026-06-30
Show the evidence
Trial
NCT06792617
"Exercise Rehabilitation in Patients With Severe Cardiopulmonary Dysfunction on Extracorporeal Life Support"; n 40; "Timing of exercises"; 2025-12
NCT07520032
"Effectiveness of Extra-corporeal Shockwave Diathermy in the Management of Upper Limb Function Patients With Stroke."; n 50; "Upper limb function test"; 2026-06-30
recorded 2026-09-01 · last checked 2026-09-04
Q8
Which 3 trials of Camphor Oil posted no result?
Posted no result
3 of 3 completed trials
Registrations
NCT02148731, NCT02716480 and NCT06400134
Completion dates
oldest 2015-12; newest 2022-09-30
Show the evidence
Trial
NCT02148731
2015-12
NCT02716480
2018-08
NCT06400134
2022-09-30
Q9
At the median, Camphor Oil's trials enrolled 50 people — anything larger?
Median enrolment
50
Largest enrolment
180
Registered trials counted
9
Q10
Was Camphor Oil studied with exercise?
exercise is named in Camphor Oil's label sentences: "In this type 1 hybrid randomized controlled trial, 459 adults with mobility disabilities were randomized to one of three groups: M2M (exercise videos), M2Mplus (exercise videos plus social networking and optional coaching), or attention control (health articles)." openfda-label+europepmc · 2026-05-28
1 recorded statement; exercise
Show the evidence
exercise
In this type 1 hybrid randomized controlled trial, 459 adults with mobility disabilities were randomized to one of three groups: M2M (exercise videos), M2Mplus (exercise videos plus social networking and optional coaching), or attention control (health articles).
recorded 2026-05-28 · last checked 2026-09-04
Q11
What is recorded about Camphor Oil and AMPK?
"In vivo, tricin extended lifespan, enhanced stress resistance, and improved mobility in <i>C. elegans</i> through <i>aak-2</i>/<i>AMPK</i>-mediated autophagy." — where Camphor Oil and AMPK appear together. Europe PMC · pathway abstract search · 2026-06-03
"In vivo, tricin extended lifespan, enhanced stress resistance, and improved mobility in <i>C. elegans</i> through <i>aak-2</i>/<i>AMPK</i>-mediated autophagy."
autophagyPMID 40243450
"In vivo, tricin extended lifespan, enhanced stress resistance, and improved mobility in <i>C. elegans</i> through <i>aak-2</i>/<i>AMPK</i>-mediated autophagy."
mTORPMID 42047332
"Exploring the intricate molecular interplay between natural products and autophagy in limiting infections may provide valuable insights that could inform the development of innovative host-directed antimicrobial treatments based on autophagy regulation.<b>Abbreviations:</b> 3-MA: 3-methyladenine; AM: alveolar macrophages; AMP: antimicrobial peptides; AMPK: 5' adenosine monophosphate-activated…"
AMPKPMID 42047332
"Exploring the intricate molecular interplay between natural products and autophagy in limiting infections may provide valuable insights that could inform the development of innovative host-directed antimicrobial treatments based on autophagy regulation.<b>Abbreviations:</b> 3-MA: 3-methyladenine; AM: alveolar macrophages; AMP: antimicrobial peptides; AMPK: 5' adenosine monophosphate-activated…"
sirtuinPMID 42047332
"Exploring the intricate molecular interplay between natural products and autophagy in limiting infections may provide valuable insights that could inform the development of innovative host-directed antimicrobial treatments based on autophagy regulation.<b>Abbreviations:</b> 3-MA: 3-methyladenine; AM: alveolar macrophages; AMP: antimicrobial peptides; AMPK: 5' adenosine monophosphate-activated…"
autophagyPMID 42047332
"Exploring the intricate molecular interplay between natural products and autophagy in limiting infections may provide valuable insights that could inform the development of innovative host-directed antimicrobial treatments based on autophagy regulation.<b>Abbreviations:</b> 3-MA: 3-methyladenine; AM: alveolar macrophages; AMP: antimicrobial peptides; AMPK: 5' adenosine monophosphate-activated…"
sirtuin
PMID 41217228
"This study examines the protective effects of trans-chalcone, a natural flavonoid, on MIR-induced myocardial damage via the Sirtuin 1 (SIRT1)-High Mobility Group Box 1 (HMGB1)-inflammasome-pyroptosis axis."
PMID 40695395
"Yeast one-hybrid and electrophoretic mobility shift assay confirmed SIRT1 binds Chlamys farreri FOXL2 via two sequences (SIF1: +28-+35; SIF2: +53-+60)."
autophagyPMID 41408474
"Gas enhanced C. elegans mobility while suppressing age-related lipofuscin deposition.Additionally, Gas lowered ROS levels and elevated antioxidant enzyme activity in C. elegans.Mechanistic studies revealed that Gas’s anti-aging effects rely on transcription factors (DAF-16, SKN-1, HSF-1) and bolster stress resistance via HSPs activation and autophagy induction."
mTORPMID 42233622
"This study suggests that WNT2B may serve as a promising therapeutic target for CD and autophagy-associated fibrotic disorders.<b>Abbreviations</b>: 3-MA: 3-methyladenine; AAV: adeno-associated virus; ACTA2: actin alpha 2, smooth muscle; ARPC2: actin related protein 2/3 complex subunit 2; ATG: autophagy related; CCN3: cellular communication network factor 3; CD: Crohn disease; CK666:…"
recorded 2026-06-03 · last checked 2026-09-04
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